Current Status of Human Adipose–Derived Stem Cells: Differentiation into Hepatocyte-Like Cells by Feras Al Battah, Joery De Kock, Tamara Vanhaecke, Vera Rogiers

“…The hASCs are multipotent MSCs that reside in adipose tissue, with the ability to self-renew and differentiate into multiple cell lineages. …”
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Adipose-Derived Stem Cells Exosomes Improve Fat Graft Survival by Promoting Prolipogenetic Abilities through Wnt/β-Catenin Pathway by Kexin Chen, Jiachao Xiong, Sha Xu, Minliang Wu, Chunyu Xue, Minjuan Wu, Chuan Lv, Yuchong Wang

“…Autologous fat grafting has been widely used in plastic surgery in recent years, but the unstable retention of fat graft has always been a key clinical problem. Adipose tissue has poor tolerant to ischemia, so the transplanted adipose tissue needs to rebuild blood supply at an early stage in order to survive stably. …”
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A Potential Linking between Vitamin D and Adipose Metabolic Disorders by Zhiguo Miao, Shan Wang, Yimin Wang, Liping Guo, Jinzhou Zhang, Yang Liu, Qiyuan Yang

“…Besides its role in calcium homeostasis and energy metabolism, vitamin D is also involved in the regulation of development and process of metabolic disorders. Adipose tissue is a major storage depot of vitamin D. …”
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Epicardial Fat: Physiological, Pathological, and Therapeutic Implications by Juan Salazar, Eliana Luzardo, José Carlos Mejías, Joselyn Rojas, Antonio Ferreira, José Ramón Rivas-Ríos, Valmore Bermúdez

“…Epicardial fat is closely related to blood supply vessels, both anatomically and functionally, which is why any change in this adipose tissue’s behavior is considered a potential risk factor for cardiovascular disease development. …”
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Unilocular adipocyte and lipid tracer for immunofluorescent images by Elizabeth K. Johnston, Tal Dassau, Nickia A. Muraskin, Rosalyn D. Abbott

“…Abstract Adipose tissue is a highly dynamic endocrine organ that serves as the body’s primary energy reservoir through the storage and mobilization of lipids. …”
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Improvement of the Survival of Human Autologous Fat Transplantation by Adipose-Derived Stem-Cells-Assisted Lipotransfer Combined with bFGF by Aimei Jiang, Ming Li, Wenjing Duan, Yilong Dong, Yanmei Wang

“…Adipose-derived stem cells (ASCs) transplanted along with autologous adipose tissue may improve fat graft survival; however, the efficacy of ASCs has been diluted by low vascularization. …”
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The Use of Adipose-Derived Mesenchymal Stem Cells in the Treatment of Claw Lesions in Cows by Nataly Kostyuk, Andrei Prytychenka

“…The mesenchymal stem cells-based therapy may be used for wound healing in cow hooves. Keywords: Adipose tissue, claws and hooves, dairy cow, mesenchymal stem cells, wound healing. …”
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Adipocytokines in Atherothrombosis: Focus on Platelets and Vascular Smooth Muscle Cells by Giovanni Anfossi, Isabella Russo, Gabriella Doronzo, Alice Pomero, Mariella Trovati

“…The increased vascular risk is related also to peculiar dysfunction in the endocrine activity of adipose tissue responsible of vascular impairment (including endothelial dysfunction), prothrombotic tendency, and low-grade chronic inflammation. …”
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Effect of gonadectomy and estradiol on the expression of insulin signaling cascade genes in female and male mice by T. V. Iakovleva, N. E. Kostina, E. N. Makarova, N. M. Bazhan

“…Also, estradiol seems to regulate the transport of glucose in adipose tissue regardless of animal sex: in females and males, an increase in the blood estradiol level was associated with a decrease in the expression of the Slc2a4 gene in adipose tissue. …”
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Adipocyte-specific Steap4 deficiency reduced thermogenesis and energy expenditure in mice by Han Wang, Lizi Zhang, Xing Chen, Lingzi Hong, Junjie Zhao, Wen Qian, Lam Khue Pham, Belinda Willard, Xiaoxia Li, Katarzyna Bulek, Xiao Li

“…Summary: Six-transmembrane protein of prostate 4 (Steap4), highly expressed in adipose tissue, is associated with metabolic homeostasis. …”
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Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice by Yan Yang, Wenting Zhang, Xiaohui Wu, Jing Wu, Chengjun Sun, Feihong Luo, Zhou Pei

“…Systemic overexpression of GDF5 in adipose tissue in vivo significantly reduced HFD-induced NAFLD liver damage in mice. …”
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Myristoylated Eepd1 Enhances Lipolysis and Thermogenesis through PKA Activation to Combat Obesity by Suzhen Chen, Yanping Wang, Qian Zhou, Qiqi Qian, Quanxin Jiang, Chuchu Liu, Yan Liu, Peihui Zhou, Jie Xiong, Yao Zhang, Ning Wang, Yang Emma Li, Limin Yin, Hongyuan Yang, Junli Liu

“…Here, we explore the role of Eepd1, a DNA repair enzyme, in regulating adipose tissue function and obesity onset. Eepd1 is primarily expressed in adipose tissue, where its downregulation or deletion accelerates obesity development. …”
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The Polycystic Ovary Syndrome and the Metabolic Syndrome: A Possible Chronobiotic-Cytoprotective Adjuvant Therapy by Eduardo Spinedi, Daniel P. Cardinali

“…Dysfunctional white adipose tissue has been identified as a major contributing factor for insulin resistance in polycystic ovary syndrome. …”
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Cross-Talk between PPARγ and Insulin Signaling and Modulation of Insulin Sensitivity by Anna Leonardini, Luigi Laviola, Sebastio Perrini, Annalisa Natalicchio, Francesco Giorgino

“…PPARγ activation in type 2 diabetic patients results in a marked improvement in insulin and glucose parameters, resulting from an improvement of whole-body insulin sensitivity. Adipose tissue is the major mediator of PPARγ action on insulin sensitivity. …”
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Calorie Restriction with a High-Fat Diet Effectively Attenuated Inflammatory Response and Oxidative Stress-Related Markers in Obese Tissues of the High Diet Fed Rats by Seungae Park, Na-Young Park, Giuseppe Valacchi, Yunsook Lim

“…Obesity characterized by increased mass of adipose tissue leads to systemic inflammation. Calorie restriction (CR) improves parameters associated with immune response and antioxidant defense. …”
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Extensive Sclerosing Mesenteritis of the Rectosigmoid Colon Associated with Erosive Colitis by C. Nobili, L. Degrate, R. Caprotti, C. Franciosi, B. E. Leone, F. Romano, M. Dinelli, Fr. Uggeri

“…Sclerosing mesenteritis is a rare, idiopatic, usually benign, inflammatory process of the mesenteric adipose tissue. The most common site of involvement is the small bowel mesentery. …”
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Adipose-Derived Stem Cells Are an Efficient Treatment for Fistula-in-ano of Japanese Rabbit by Xiao Qin, Peng Wang, Yongming Huang, Yansen Li, Min Chao, Wei Wang

“…Fistula-in-ano (FIA, anal fistula) treatment remains a surgical challenge for coloproctologists. Adipose tissue-derived stem cells (ADSCs) are a new frontier in the treatment of FIA. …”
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Mitochondria in White, Brown, and Beige Adipocytes by Miroslava Cedikova, Michaela Kripnerová, Jana Dvorakova, Pavel Pitule, Martina Grundmanova, Vaclav Babuska, Dana Mullerova, Jitka Kuncova

“…Mitochondria play a key role in energy metabolism in many tissues, including cardiac and skeletal muscle, brain, liver, and adipose tissue. Three types of adipose depots can be identified in mammals, commonly classified according to their colour appearance: the white (WAT), the brown (BAT), and the beige/brite/brown-like (bAT) adipose tissues. …”
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Circulating Levels of Inflammatory Markers in Intrauterine Growth Restriction by Theodora Boutsikou, George Mastorakos, Marialena Kyriakakou, Alexandra Margeli, Demetrios Hassiakos, Ioannis Papassotiriou, Christina Kanaka-Gantenbein, Ariadne Malamitsi-Puchner

“…We conclude that the lack of difference in hs-CRP, PAI-1 and S100B levels, between IUGR and AGA fetuses/neonates—despite the lower birth weight, reflecting reduced fat mass in the former—might indicate more intense adipose tissue and nervous system inflammation in IUGRs. …”
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Lupeol Attenuates Palmitate-Induced Hypertrophy in 3T3-L1 Adipocytes by Vaithinathan Selvaraju, Shivani R. Babu, Robert L. Judd, Thangiah Geetha

“…Obesity is characterized by the enlargement of adipose tissue due to an increased calorie intake exceeding the body’s energy expenditure. …”
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