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Generalized cue reactivity in rat dopamine neurons after opioids
Published 2025-01-01“…These results challenge the prevailing hypothesis of cue reactivity, warranting revised models of dopaminergic function in opioid addiction, and provide insights into the neurobiology of cue reactivity with potential implications for relapse prevention.…”
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542
Role of Hypothalamus in Acupuncture’s Effects
Published 2025-01-01“…Acupuncture, a traditional oriental medicine, can affect brain regions, such as the hypothalamus, anterior cingulate, posterior cingulate, and hippocampus, and produces specific therapeutic effects, such as pain relief, suppression of hypertension, and alleviation of drug addiction. Among the brain regions, the hypothalamus, a small yet critical region in the brain, plays a pivotal role in maintaining homeostasis by regulating a wide array of physiological processes, including stress responses, energy balance, and pain modulation. …”
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543
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La Costituzione siciliana del 1812
Published 2017-01-01“…The Constitution provider for separation of powers but the English Constitutionl mo - del couldn’t be put into practice because it was based on royal assent, (the King can do no wrong) and this interna corporis whic would be led to the impeachment as being a political responsibility not a juridical responsibility. There was the addiction of feudalism but all feudal possession were transformed in Habeas corpus. …”
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545
Pain management for the neurosurgical patient in spinal procedures: overview of historic and new modalities
Published 2024-05-01“…The potent pain-relieving properties of opioids come at a steep price. Their addictive nature and side effects raise critical concerns in managing pain after surgical spine procedures. …”
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546
Community mental health funding, stakeholder engagement and outcomes: a realist synthesis
Published 2023-02-01Get full text
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547
Low-tech serious games in higher education: bridging the digital divide and enhancing student thinking and performance
Published 2025-01-01“…However, such digital-focused approaches risk widening the digital divide and may lead to digital addiction. Additionally, games rooted in behaviorism may not meaningfully improve student performance. …”
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548
Impact of the Aversive Effects of Drugs on Their Use and Abuse
Published 2022-01-01“…A recent model of the addiction cycle (as proposed by Koob and his colleagues) illustrates how drug-taking patterns transition from impulsive (acute use) to compulsive (chronic use) as a function of various neuroadaptations leading to the downregulation of DA systems, upregulation of stress systems, and the dysregulation of the prefrontal/orbitofrontal cortex. …”
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549
Development and achievement of aspirations among unaccompanied refugee minors
Published 2025-12-01Get full text
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550
Sociodemographic characteristics and vaping motives as potential correlates of early vaping initiation
Published 2025-01-01“…Reducing EVI is particularly important, as vaping often begins at an early age, and early intervention is vital to prevent early initiation and subsequent addiction.…”
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551
The Effects of the COVID-19 on Our Daily Lives in Bangladesh
Published 2022-02-01“…The most frightening thing was that the addiction to the virtual world had increased dramatically. …”
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552
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„Nowe” problemy wychowawcze w dobie „nowych” mediów
Published 2012-12-01“…The computer network addicts and leaves sometimes dramatic marks in their lives. …”
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554
Analysis of College Students’ Public Opinion Based on Machine Learning and Evolutionary Algorithm
Published 2019-01-01“…The recent information explosion may have many negative impacts on college students, such as distraction from learning and addiction to meaningless and fake news. To avoid these phenomena, it is necessary to verify the students’ state of mind and give them appropriate guidance. …”
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555
Distinct cortico-striatal compartments drive competition between adaptive and automatized behavior.
Published 2023-01-01“…In this study, we investigate the cortico-striatal circuitry involved in learning and the role of this circuitry in the emergence of inflexible behaviors such as those observed in addiction. Specifically, we develop a computational model of cortico-striatal interactions that performs concurrent goal-directed and habit learning. …”
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556
Ultrasound Radiogenomics-based Prediction Models for Gene Mutation Status in Breast Cancer
Published 2025-03-01Get full text
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557
Cognitive deficits persisting in patients with alcohol dependence syndrome after detoxification
Published 2024-12-01“…Materials and Methods: The study included randomly selected, consenting, non-delirious patients of alcohol dependence syndrome (ADS) without dementia, admitted in the de-addiction ward. Cognition was assessed by Mini Mental State Examination (MMSE) of the Diagnostic Interview for Genetic Studies at admission and after 7 days of detoxification. …”
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558
Is there a risk of esketamine misuse in clinical practice?
Published 2025-01-01“…Despite initial concerns, long-term clinical studies have not documented instances of abuse, misuse, addiction or withdrawal, and the same was found in case reports or subsamples of high-risk populations with comorbidities such as substance use disorder or alcohol use disorder. …”
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Health profile assessment of school children of Jodhpur District of Rajasthan
Published 2025-01-01“…The objectives of this study were to assess the health profile including general physical examination, anthropometric measurements, morbidity pattern and addiction among school-going children of Jodhpur. Material and Methods: A school-based observational cross-sectional study was carried out among the nearby schools pertaining to our urban and rural health centres associated with the Department of Community Medicine and Family Medicine, AIIMS Jodhpur. …”
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Abuse potential of fentanyl and fentanyl analogues
Published 2024-11-01“…Conclusions: By educating patients and physicians, making rescue kits easily accessible, developing vaccines to prevent opioid addiction, and perhaps even creating new tamper-resistant fentanyl formulations, it may be possible to prevent fentanyl misuse, therapeutic errors, and the repercussions that follow.…”
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