Patient outcomes and health care resource utilization in acute pancreatitis-related central nervous system complications: insights from a national cohort study by Muhammad Shahzil, Ammad Javaid Chaudhary, Saad Javaid, Vishali Moond, Gokturk Tepe, Muhammad Saad Faisal, Muhammad Ali Khaqan, Anas Kutait

“…Objectives Central nervous system complications of acute pancreatitis (AP) can result in cerebral edema (CE). …”
Get full text

Serum amylase level measurement in acute abdominal pain by Taher Abdullah Hawramy, Dara Ahmed Mohammed, Botan H. Tahir

Subjects: “…Acute abdominal pain, Serum amylase, Diagnosis, Acute pancreatitis, Acute calculous cholecystitis, Sensitivity, Specificity.…”
Get full text

Disrupting of IGF2BP3-stabilized CLDN11 mRNA by TNF-α increases intestinal permeability in obesity-related severe acute pancreatitis by Lihui Lin, Yansong Lin, Xianwen Guo, Ruoyi Zhang, Xin Ling, Zewen Zhang, Rong Lin, Zhen Ding

Subjects: Get full text

Association between red blood cell distribution width-to-albumin ratio at admission and all-cause mortality in patients with acute pancreatitis based on the MIMIC-III database. by Qingsong Wu, Lianyi Liao, Qingjun Deng

“…<h4>Objective</h4>The association between red blood cell distribution width-to-albumin (RDW/ALB) ratio (RAR) and all-cause mortality in patients with acute pancreatitis has not been fully delineated. The purpose of this study was to investigate the impact of RAR at admission on 28-day all-cause mortality in patients with acute pancreatitis.…”
Get full text

Response to Comment by Dr. Kuang on Our Manuscript “Immediate Oral Refeeding in Patients With Mild and Moderate Acute Pancreatitis: A Multicenter, Randomized Controlled Trial (PADI trial)” by Elena Ramírez-Maldonado, MD, PhD, Sandra López Gordo, MD, PhD, Robert Memba, MD, PhD, Rosa Jorba, MD, PhD, on behalf of the Catalan Pancreatitis Collaborative Group, Laia Blanco, Sandra M. Bacca, Joaquim Balsells, Carme Boqué, Pablo Collera Ormazabal, Daniel Coronado Llanos, Ignasi Elizalde, Laia Estalella, Maria Teresa Fernández Planas, Lidia Florit Serra, Inmaculada Fonoll, Nil Gómez Vallvé, Sergio González, Maria Alejandra Guerrero Ortíz, Jiazhen Li, Erik Llàcer-Millán, Rui Pedro Major Branco, David Nicolas, Elizabeth Pando, Mihai-Calin Pavel, Jing Quiao, Marta Rodrigo-Rodrigo, Ariadna Sánchez, Teresa Soriano, Guillem Soy, Eva Vaquero, Pengyu Wu, Heng Xi, Wen Zhong

Get full text

Emodin protects against severe acute pancreatitis-associated acute lung injury by activating Nrf2/HO-1/GPX4 signal and inhibiting ferroptosis in vivo and in vitro by Gang Shen, Haiyun Wen, Huijuan Li, Xuetao Zhang, Bowen Lan, Xuanchi Dong, Peng Ge, Yalan Luo, Hailong Chen

“…Abstract Background Severe acute pancreatitis (SAP) has high morbidity, a complicated and dangerous course, and many complications, including severe pulmonary complications. …”
Get full text

Metabolic Risk Factors and Their Impact on Quality of Life in Patients with Pancreatic Cancer, Acute or Exacerbated Chronic Pancreatitis by I. N. Grigor’eva, O. V. Efimova, N. L. Tov, T. S. Suvorova, D. L. Nepomnyashchikh

Subjects: Get full text

Identification of a novel heterozygous GPD1 missense variant in a Chinese adult patient with recurrent HTG-AP consuming a high-fat diet and heavy smoking by Xiao-Yao Li, Bei-Yuan Zhang, Xin-Ran Liang, Yan-Yu Han, Min-Hua Cheng, Mei Wei, Ke Cao, Xian-Cheng Chen, Ming Chen, Jian-Feng Duan, Wen-Kui Yu

Subjects: “…Hypertriglyceridemia-induced acute pancreatitis…”
Get full text

FTO attenuates TNF-α-induced damage of proximal tubular epithelial cells in acute pancreatitis-induced acute kidney injury via targeting AQP3 in an N6-methyladenosine-dependent manner by Xinghui Li, Qi Liang, Lu Liu, Shujun Chen, Yong Li, Yu Pu

“…Background Acute kidney injury (AKI) is a frequent complication of severe acute pancreatitis (SAP). Previous investigations have revealed the involvement of FTO alpha-ketoglutarate-dependent dioxygenase (FTO) and aquaporin 3 (AQP3) in AKI. …”
Get full text

Early Changes in Blood Urea Nitrogen (BUN) Can Predict Mortality in Acute Pancreatitis: Comparative Study between BISAP Score, APACHE-II, and Other Laboratory Markers—A Prospective Observational Study by Elizabeth Pando, Piero Alberti, Rodrigo Mata, María José Gomez, Laura Vidal, Arturo Cirera, Cristina Dopazo, Laia Blanco, Concepción Gomez, Mireia Caralt, Joaquim Balsells, Ramón Charco

“…Changes in BUN have been proposed as a risk factor for complications in acute pancreatitis (AP). Our study aimed to compare changes in BUN versus the Bedside Index for Severity in Acute Pancreatitis (BISAP) score and the Acute Physiology and Chronic Health Evaluation-II score (APACHE-II), as well as other laboratory tests such as haematocrit and its variations over 24 h and C-reactive protein, in order to determine the most accurate test for predicting mortality and severity outcomes in AP. …”
Get full text

Association between red cell distribution width to albumin ratio and all-cause mortality in patients with acute pancreatitis admitted to the intensive care unit: a retrospective study based on the MIMIC-IV database by Xuan Chen, Yuchen Luo, Side Liu

Subjects: Get full text

Prediction Models of Severity in Acute Biliary Pancreatitis by Iulia Ratiu, Renata Bende, Camelia Nica, Oana Budii, Calin Burciu, Andreea Barbulescu, Tudor Moga, Bogdan Miutescu, Roxana Sirli, Mirela Danila, Alina Popescu, Felix Bende

“…<b>Background:</b> Acute pancreatitis is a common condition with a variable prognosis. …”
Get full text

Ultrasound diagnostics of traumatic pancreatitis at combined trauma by O. A. Alekseyechkina, E. Ya. Dubrov, D. A. Kosolapov, V. M. Abuchina

“…In patients with combined trauma and closed injury of the abdomen signs of acute pancreatitis emerged, as a rule, on the 1–7 day after the moment of trauma. …”
Get full text

Astaxanthin Inhibits Interleukin-6 Expression in Cerulein/Resistin-Stimulated Pancreatic Acinar Cells by Min Seung Kwak, Joo Weon Lim, Hyeyoung Kim

“…Obesity is a negative prognostic factor in acute pancreatitis. Obese patients with acute pancreatitis have a higher systemic inflammatory response rate. …”
Get full text

Moderate Hypertriglyceridemia Causing Recurrent Pancreatitis: A Case Report and the Literature Review by Vijay Gayam, Amrendra Kumar Mandal, Pavani Garlapati, Mazin Khalid, Arshpal Gill, Khalid Mowyad

“…Recurrent acute pancreatitis secondary to hypertriglyceridemia (HTG) with levels below 1000 mg/dL has been rarely reported in the literature. …”
Get full text

Severe Hypertriglyceridemia Induced Pancreatitis in Pregnancy by Natasha Gupta, Seema Ahmed, Lemuel Shaffer, Paula Cavens, Josef Blankstein

“…Acute pancreatitis caused by severe gestational hypertriglyceridemia is a rare complication of pregnancy. …”
Get full text

Metronidazole-Induced Pancreatitis: Is There Underrecognition? A Case Report and Systematic Review of the Literature by Ibrahim Youssef, Naba Saeed, Mohammad El Abdallah, Kara Huevelhorst, Kais Zakharia

“…Introduction. Acute pancreatitis (AP) is the most common cause of gastroenterological hospitalization in the USA, with a mortality ranging from 5 to 20%. …”
Get full text

Activated Protein C Does Not Alleviate the Course of Systemic Inflammation in the APCAP Trial by Lea Kyhälä, Panu Mentula, Leena Kylänpää, Eeva Moilanen, Pauli Puolakkainen, Ville Pettilä, Heikki Repo

“…The study aimed to determine the effect of the activated protein C on the course of systemic inflammation in the APCAP (activated protein C in acute pancreatitis) trial where we randomized 32 patients with severe acute pancreatitis to receive either recombinant activated protein C (drotrecogin alfa activated) (n=16) or placebo (n=16) for 96 hours. …”
Get full text

Pancreatitis with Electrocardiographic Changes Mimicking Acute Myocardial Infarction by Paul Khairy, Pierre Marsolais

“…A 64-year-old woman with mild acute pancreatitis presented with epigastric pain, nausea and vomiting while undergoing hemodialysis for chronic renal insufficiency. …”
Get full text

Pancreaticopleural Fistula Causing Massive Right Hydrothorax and Respiratory Failure by Esther Ern-Hwei Chan, Vishalkumar Girishchandra Shelat

“…Hydrothorax secondary to a pancreaticopleural fistula (PPF) is a rare complication of acute pancreatitis. In patients with a history of pancreatitis, diagnosis is made by detection of amylase in the pleural exudate. …”
Get full text