Paracetamol-induced hepatotoxicity in a malnourished patient: A case report by Sudhanshu Shukla, Tejashree Sridhar, Jayasheela Siddalingayya Hiremath, Sanathkumar B. Nyamagoud, Viswanatha Agadi Hiremath Swamy

“…However, excessive doses can lead to severe hepatotoxicity and acute liver failure. We present a case report that describes the unfortunate demise of a 48-year-old male patient with colon carcinoma who developed severe hepatotoxicity attributed to the administration of paracetamol following right radical hemicolectomy. …”
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Pathogenesis of Hepatic Encephalopathy by Irena Ciećko-Michalska, Małgorzata Szczepanek, Agnieszka Słowik, Tomasz Mach

“…Hepatic encephalopathy can be a serious complication of acute liver failure and chronic liver diseases, predominantly liver cirrhosis. …”
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Two Case Reports on Thalamic and Basal Ganglia Involvement in Children with Dengue Fever by Guwani Liyanage, Lihini Adhikari, Saraji Wijesekera, Maheshaka Wijayawardena, Suchithra Chandrasiri

“…Such unusual manifestations including acute liver failure and encephalopathy could be manifested even in the absence of significant plasma leakage. …”
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Successful Treatment of Crizotinib-Induced Fulminant Liver Failure: A Case Report and Review of Literature by Kyle Kreitman, Satheesh P. Nair, Jiten P. Kothadia

“…We report a case of a 46-year-old female with a history of metastatic lung cancer who presented with acute liver failure after being on crizotinib for two months. …”
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Bioartificial Liver Support by Vincent G Bain, Jose Luis Montero, Manuel de la Mata

“…The concept is attractive because, if it is effective, patients with acute liver failure may be supported until native liver regeneration occurs or, by optimizing their condition, until liver transplantation is possible. …”
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Autoimmune Hepatitis—Immunologically Triggered Liver Pathogenesis—Diagnostic and Therapeutic Strategies by Elisabeth Sucher, Robert Sucher, Tanja Gradistanac, Gerald Brandacher, Stefan Schneeberger, Thomas Berg

“…AIH responds favorably to steroids and pharmacologic immunosuppression, and liver transplantation is only necessary in cases with acute liver failure or end-stage liver cirrhosis. Recurrence or development of de novo AIH after transplantation is possible, and treatment is similar to standard AIH therapy. …”
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A Rare Case of Herpes Simplex Virus-2 Hepatitis with Negative Serology by Mohanad Soliman, Olalekan Akanbi, Ihab Almagdub, Kishore Karri, Pradeep Yarra, Saad Emhmed Ali, Hanine El Haddad

“…Herpes simplex virus-2 (HSV2) hepatitis represents a rare but serious complication of HSV2 infection that can progress to acute liver failure (ALF). We describe a case of a pregnant teenager who presented with four days of fever, headache, malaise, nausea, and vomiting. …”
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Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature by Rohini R. Vanga, Bikram Bal, Kevin W. Olden

“…We describe here the case of a 55-year-old woman who developed acute liver failure during the treatment of ADHD with Adderall. …”
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Herpes Simplex Virus-2 Hepatitis: A Case Report and Review of the Literature by Amna Ahmed, Alejandro Granillo, Ethan Burns, Kerri Glassner, Nishath Naseem, Christopher Force, Suzanne M. Crumley, Ashley Drews

“…Herpes simplex virus (HSV) is a rare cause of hepatitis in pregnancy and the chronically immunosuppressed, with a high propensity to progress to acute liver failure (ALF) and death. Patients typically present with a nonspecific clinical picture that often delays diagnosis and treatment, contributing to the high mortality rate. …”
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Postinfantile Giant Cell Hepatitis with Features of Acute Severe Autoimmune Hepatitis Probably Triggered by Diclofenac in a Patient with Primary Myelofibrosis by Pinelopi Arvaniti, Kalliopi Zachou, George K. Koukoulis, George N. Dalekos

“…The patient was started on corticosteroids but she did not respond and died 3 days later because of advanced acute liver failure. Postmortem liver biopsy showed typical PIGCH lesions. …”
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The Link between Hypersensitivity Syndrome Reaction Development and Human Herpes Virus-6 Reactivation by Joshua C. Pritchett, Radu M. Nanau, Manuela G. Neuman

“…Drugs identified as causes of (i) idiosyncratic reactions, (ii) drug-induced hypersensitivity, drug-induced hepatotoxicity, acute liver failure, and Stevens-Johnson syndrome, and (iii) human herpes virus reactivation in PubMed since 1997 have been collected and discussed. …”
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Diphenhydramine as a Cause of Drug-Induced Liver Injury by Yunseok Namn, Yecheskel Schneider, Isabelle H. Cui, Arun Jesudian

“…Drug-induced liver injury (DILI) is the most common cause of acute liver failure in the Unites States and accounts for 10% of acute hepatitis cases. …”
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A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis—A Case Report with Literature Review by Olivia Allen, Ahmed Edhi, Adam Hafeez, Alexandra Halalau

“…Hepatitis A is a common viral infection with a benign course but in rare cases can progress to acute liver failure. It usually presents with abdominal pain, nausea, vomiting, diarrhea, jaundice, anorexia, or asymptomatically, but it can also present atypically with relapsing hepatitis and prolonged cholestasis. …”
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Management of Acute Wilsonian Hepatitis with Severe Hemolysis: A Successful Combination of Chelation and MARS Dialysis by Jeremy Hassoun, Nathalie Hammer, Giulia Magini, Belen Ponte, Marie Ongaro, Anne-Laure Rougemont, Nicolas Goossens, Jean-Louis Frossard, Laurent Spahr

“…Wilson’s disease is a rare hereditary disorder of copper metabolism leading to progressive accumulation of copper in several organs including the brain and the liver. Acute liver failure is a relatively rare hepatic manifestation of WD which may require urgent liver transplantation if medical treatment fails. …”
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The Case for Improved Interprofessional Care: Fatal Analgesic Overdose Secondary to Acute Dental Pain during Pregnancy by Sarah K. Y. Lee, Rocio B. Quinonez, Alice Chuang, Stephanie M. Munz, Darya Dabiri

“…This case report follows a 19-year-old pregnant female presenting with acute liver failure secondary to acetaminophen overdose for management of dental pain following extensive dental procedures. …”
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Kynurenic Acid Protects against Thioacetamide-Induced Liver Injury in Rats by Sebastian Marciniak, Artur Wnorowski, Katarzyna Smolińska, Beata Walczyna, Waldemar Turski, Tomasz Kocki, Piotr Paluszkiewicz, Jolanta Parada-Turska

“…Acute liver failure (ALF) is a life-threatening disorder of liver function. …”
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Thromboelastometry Identified Alteration of Clot Stabilization and Factor XIII Supplementation Need in a Patient with Decompensated Liver Disease Undergoing Liver Biopsy by Tomaz Crochemore, Felicio Aragão Savioli

“…We report the case of a previously healthy 38-year-old man, who presented to our emergency department with clinical signs of rapid progression of acute liver failure. The laboratory tests revealed platelets of 142x103/mm3, plasma fibrinogen concentration of 221 mg/dl, increased international nationalized ratio (INR 1.9), total bilirubin of 3.9mg/dl, direct bilirubin of 2.3mg/dl, ALT 751U/l, and AST 540U/l without acute bleeding. …”
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Analysis of poisoning with OTC drugs for suicidal purposes among children and adolescents in Poland in the period 2012 - 2023 by Maria Kubicka, Paulina Polańska, Marta Gruszka, Martyna Zakrocka

“…Paracetamol poisoning remains the leading cause of intentional overdoses, with severe cases potentially resulting in acute liver failure or death if untreated. Girls account for a disproportionate number of cases, and many adolescents who attempt suicide lack prior psychiatric diagnoses. …”
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Herpes Simplex Virus Hepatitis in an Immunocompetent Host Resembling Hepatic Pyogenic Abscesses by Carrie Down, Amit Mehta, Gayle Salama, Erika Hissong, Russell Rosenblatt, Michael Cantor, David Helfgott, Kristen Marks

“…Herpes simplex virus (HSV) hepatitis represents a rare complication of HSV infection, which can progress to acute liver failure and, in some cases, death. We describe an immunocompetent 67-year-old male who presented with one week of fever and abdominal pain. …”
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ABO-incompatible liver transplantation – exploring utilitarian solutions to restricted access and organ shortages: A single-centre experience from Johannesburg, South Africa by E U Wessels, J Loveland, H Maher, P Gaylard, B Bobat, A D Mahomed, D Parbhoo, M R Beretta, C Hajinicolaou, P Walabh, S Berkenfeld, D Demopoulos, S Rambarran, B Ströbele, F van der Schyff, J Fabian, L Brannigan

“…Liver transplantation is the definitive management for severe acute liver failure refractory to supportive management, and end- stage chronic liver failure. …”
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