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50561
Biodiversity Patterns of Rocky Coastal and Human-Made Structures in Gheshm Shorelines; Role of Slope and Tidal Levels Characteristics in Determining Patterns of Biodiversity
Published 2024-10-01“…Introduction: The coastal landscapes are constantly changing due to the increasing demand for structures aimed at economic, residential, and tourism activities. Human-made constructions such as breakwaters, piers, and seawalls have become characteristic features alongside shallow habitats in intertidal and subtidal zones. …”
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50562
Evaluation of Simulated Weightlessness Model of Hindlimb Unloading Miniature Pigs and Their Tissue Damage
Published 2024-10-01“…Additionally, western blotting was employed to detect the expression levels of skeletal muscle atrophy-related proteins, including muscle-specific RING finger protein 1 (MuRf-1) and muscle atrophy F-box (MAFbx, as known as Atrogin-1), while immunohistochemistry was used to detect the expression of glial fibrillary acidic protein (GFAP), an indicator of astrocyte activation in the brain, reflecting the pathophysiological functional changes across systems. …”
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50563
Characterization of a novel covS SNP identified in Australian group A Streptococcus isolates derived from the M1UK lineage
Published 2025-02-01“…The resulting CovSAla318Val mutation caused a significant upregulation of SLO resulting in increased inflammasome activation in human THP-1 macrophages, indicating an enhanced inflammatory potential. …”
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50564
L’aqueduc du Gier à Lyon : la complexité de la protection au titre des monuments historiques
Published 2023-12-01“…He then began to travel and draft reports about the country’s ancient buildings. This active approach led to the presentation in 1840 of the first list of ancient buildings requiring preservation. …”
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50565
GPR87 promotes invasion and migration through the RHO/ROCK pathway in non-small cell lung cancer
Published 2024-12-01“…In SK-MES-1 and A549 cells, GPR87 can activate the RHOA/ROCK1 signaling pathway, promote the expression of MMPs, and ultimately promote the invasion and migration of NSCLC.…”
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50566
Application of care bundles based on the concept of enhanced recovery after surgery in perioperative nursing of patients undergoing laparoscopic cholecystectomy (基于加速康复外科理念的集束化干预在腹...
Published 2024-05-01“…The time to first postoperative exhaustion, time to off-bed activities and hospital stays in the observation group were shorter than those in the control group (P<0. 05). …”
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50567
THE PUBLIC DEBT OF UKRAINE: A NEW DIMENSION OF DYNAMICS AND ARCHITECTURE OF THE MODEL FRAMEWORK OF THE MANAGEMENT SYSTEM
Published 2024-12-01“…In this context, it is assumed that one of the conditions for the successful implementation of the fiscal correction is the completion of the active phase of the war by the end of 2025 and the consideration of additional caveats regarding the maintenance of a high debt burden in the short, medium and probably the long term perspective due to significant budgetary costs for reconstruction of infrastructure, social protection and economic development. …”
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50568
The Benefits of Using a Small Caliber Ureteroscope in Evaluation and Management of Urethral Stricture
Published 2018-01-01“…If the urethral caliber is >4.5 Fr and particularly those who are sexually active, ventral inlay with buccal mucosal grafts (BMGs) is performed. …”
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50569
Progress of research on aviation kerosene preparation using bioethanol
Published 2025-03-01“…The catalyst, with its satisfactory water resistance, can retain its activity and selectivity for high-carbon alcohols even in the presence of water and effectively inhibit the interference of water molecules, thereby increasing the efficiency and stability of the catalytic reaction. …”
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50570
Clozapine for Treatment-Resistant Disruptive Behaviors in Youths With Autism Spectrum Disorder Aged 10-17 Years: Protocol for an Open-Label Trial
Published 2025-01-01“… BackgroundAutism Spectrum Disorder (ASD) is a complex neurodevelopmental condition emerging in early childhood, characterized by core features such as sociocommunicative deficits and repetitive, rigid behaviors, interests, and activities. In addition to these, disruptive behaviors (DB), including aggression, self-injury, and severe tantrums, are frequently observed in pediatric patients with ASD. …”
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50571
Divulgação de evidências científicas sobre Práticas Integrativas e Complementares em Saúde
Published 2025-02-01“…For this purpose, 212 summarized texts were posted, elaborated by the team, and based on scientific articles, in addition to dissemination of other content and activities relevant to this area. The PICS were carried out in person and online, contributing to the participation of different audiences in various places. …”
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50572
Depressive symptoms among the oldest-old in China: a study on rural-urban differences
Published 2024-12-01“…Conclusions The oldest-old (aged 80+) adults in rural areas had a higher prevalence of depressive symptoms than that in urban areas, mostly attributed to variations in income, marital status, physical activity, and health status. These findings can help government agencies design targeted and precise intervention strategies (e.g., health education, improving medical security, and providing sports venues and equipment) to improve mental health and lower the risk of depression among the oldest population.…”
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50573
Vertical gradients of neutral winds observed by ICON and estimated by the Horizontal Wind Model during the geomagnetic storm on August 26−28, 2021
Published 2025-01-01“…Both meridional and zonal winds during the active geomagnetic period observed by ICON show distinguishable vertical shear structures at different stages of the storm. …”
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50574
Transurethral Water Vapor Ablation: Potential for a Novel Prostate Cancer Management Strategy
Published 2025-02-01“…Currently, many men with low-risk disease are offered active surveillance, during which the prostate cancer is closely monitored for any changes, whereas men with intermediate or high-risk localized cancers are more often considered for surgical removal of the prostate or treatment with radiation. …”
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50575
Speciation of Potentially Carcinogenic Trace Nickel(II) Ion Levels in Human Saliva: A Sequential Metabolomics-Facilitated High-Field <sup>1</sup>H NMR Investigation
Published 2024-12-01“…<b>Introduction/Objectives:</b> Since the biological activities and toxicities of ‘foreign’ and/or excess levels of metal ions are predominantly determined by their precise molecular nature, here we have employed high-resolution <sup>1</sup>H NMR analysis to explore the ‘speciation’ of paramagnetic Ni(II) ions in human saliva, a potentially rich source of biomolecular Ni(II)-complexants/chelators. …”
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50576
NaHS alleviates neuropathic pain in mice by inhibiting IL-17-mediated dopamine (DA) neuron necroptosis in the VTA
Published 2025-01-01“…It has been revealed that inflammatory activation triggers necroptosis by stimulating mixed lineage kinase domain-like protein (MLKL), leading to progressive neuronal demise. …”
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50577
Preventing sensory and motor dysfunctions in children receiving neurotoxic chemotherapy: PrepAir study - an update
Published 2025-01-01“…In addition, numerous secondary endpoints such as postural control, strength of the lower limbs, CIPN-related pain, movement-related leisure activities, physical self-concept and quality of life are assessed. …”
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50578
N‐terminal pro brain natriuretic peptide reference values in community‐dwelling older adults
Published 2022-06-01“…Methods and results We analysed established NT‐proBNP predictors using quantile regression among 2459 participants of two‐independent population‐based cohorts located in Germany, the Activity and Function in the Elderly Study (ActiFE, n = 1450) and the Study of Health in Pomerania (SHIP‐TREND‐0, n = 1009). …”
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50579
Regulatory Role of rno-miR-30b-5p in IL-10 and Toll-like Receptor 4 Expressions of T Lymphocytes in Experimental Autoimmune Uveitis In Vitro
Published 2018-01-01“…In this study, the regulatory role of rno-miR-30b-5p in IL-10 and TLR4 gene expressions was validated using luciferase activity assay. Further, the inflammatory manifestation of the anterior segment and pathological examination of the eye were explored in experimental autoimmune uveitis (EAU) rats. …”
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50580
Utility of 131I-HLX58-Der for the Precision Treatment: Evaluation of a Preclinical Radio-Antibody-Drug-Conjugate Approach in Mouse Models
Published 2025-01-01“…In terms of cytotoxicity, 131I-HLX58-Der exhibited greater activity compared to HLX58-Der. 125I-HLX58 and 131I-HLX58-Der demonstrated similar biodistribution profiles in CLDN18.2-positive tumor models, achieving 5.72 ± 0.41%ID/g (48 h) and 5.83 ± 0.41%ID/g (72 h) in the tumor tissues postinjection, respectively. …”
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