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50181
Analogs of Precambrian microbial communities formed de novo in Caucasian mineral water aquifers
Published 2025-01-01“…Among the YMWB strata, the Upper Jurassic aquifer, supersaturated with CO2, influenced by magmatic activity, and highly enriched with thermophilic autotrophic hydrogenotrophic acetogens, turned out to be the first described modern ecosystem based on the primary production by a process predicted to support the Last Universal Common Ancestor (LUCA). …”
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50182
Occupational skin diseases among bricklayers and brick masons in a resource poor setting, Southwest Nigeria: prevalence and correlates – a case–control study
Published 2025-01-01“…Objectives Cement and most other materials used by bricklayers and brick masons for construction purposes could heighten the risk for occupational skin diseases (OSDs) which mostly include occupational contact dermatitis (OCD) and others. The activities of the bricklayers or brick masons are essentially manual as they work as artisans involving mixing sands and gravels with cement and water for building and block moulding, respectively. …”
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50183
Prenatal vitamin utilization and its determinants among pregnant women in south Gondar zone: multicenter cross-sectional study
Published 2025-01-01“…Developing and implementing targeted educational programs to increase awareness about the importance and benefits of prenatal vitamins and encouraging women to take an active role in their healthcare decisions is recommended to improve the utilization of prenatal vitamins.…”
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50184
Evaluation of the Therapeutic Effect of Traditional Chinese Medicine on Osteoarthritis: A Systematic Review and Meta-Analysis
Published 2020-01-01“…In addition, the experimental group was also superior to the control group in terms of the indicators of joint activity function, inflammatory factor content, and various indicators affecting bone metabolism. …”
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50185
From fear to food: predation risk shapes deer behaviour, their resources and forest vegetation
Published 2025-01-01“…In these populations deer had a remarkable tolerance to human presence (short flight initiation and travel distances when disturbed), a willingness to consume foreign bait or to investigate baited traps, and a propensity to be active at daytime. Where deer faced long-term hunting and natural predators, understories were denser and more diverse and resembled those of forests never exposed to deer. …”
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50186
Titanium nanotubes modulate immunophenotyping and cytokine secretion of T cells via IL-17A: a bioinformatic analysis and experimental validation
Published 2025-01-01“…ObjectWe aim to explore the immunomodulatory properties of T cells on different titanium nanotubes and the key immunological factors involved in this process.MethodsTranscriptome data from GEO database of healthy people and healthy implants were used to analyze cell infiltration and factor distribution of adaptive immune using bioinformatics tools. T cells from activated rat were cultured on titanium nanotubes that were prepared by anodization with different diameters (P-0, NT15-30 nm, NT40-100 nm, NT70-200 nm). …”
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50187
Effectiveness of the Chronic Care Model in Type 2 Diabetes Management in a Community Health Service Center in China: A Group Randomized Experimental Study
Published 2019-01-01“…Health behaviors such as drinking habit (OR=0.07, 95% CI: 0.01, 0.75), physical activity (OR=2.92, 95% CI: 1.18, 7.25), and diet habit (OR=4.30, 95% CI: 1.49, 12.43) were improved. …”
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50188
mRNA-LNP vaccines combined with tPA signal sequence elicit strong protective immunity against Klebsiella pneumoniae
Published 2025-01-01“…In the present study, we aim to construct a new mRNA vaccine encoding YidR or combining with a tissue plasminogen activator signal sequence for preventing K. pneumoniae infection. …”
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50189
Functionality of endothelial cells differentiated from porcine epiblast stem cells, bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells
Published 2024-12-01“…Cells differentiated from these stem cells were isolated using CD-31 positive (+) magnetic-activated cell sorting (MACS) and then proliferated in M199 medium. …”
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50190
Multi-omics dissection of metabolic dysregulation associated with immune recovery in people living with HIV-1
Published 2025-01-01“…In TNs, metabolomic analysis revealed increased levels of 3-hydroxyoctanoic acid, 3-oxododecanoic acid, 5-hydroxy-L-tryptophan, 5-hydroxyindoleacetic acid, L-kynurenine, oleoylcarnitine, and pseudouridine that were positively correlated with CD8 T cell activation and inflammation-related markers, and decreased levels of phosphorylcholine, ribothymidine, and thymine that were negatively correlated. …”
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50191
Comparison of Therapeutic Effects of Different Rehabilitation Methods on Patients Undergoing Total Knee Arthroplasty: A Network Meta‐Analysis of Randomized Controlled Trials
Published 2025-02-01“…And we have summarized nine rehabilitation intervention measures: conventional physical therapy (CPT), cryotherapy, thermal therapy (TT), acupuncture, hydrotherapy, neuromuscular training (NT), electrotherapy, continuous passive motion (CPM), continuous active motion (CAM). And use the range of motion (ROM), visual analog scale (VAS), Western Ontario and McMaster Universities osteoarthritis index (WOMAC) as the outcome measure to evaluate the effectiveness of various interventions. …”
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50192
Effectiveness of using implementation frameworks to facilitate the implementation of a stroke management guideline in the traditional Chinese medicine hospitals in China: protocol...
Published 2025-01-01“…On completion, the findings will be shared with patients, healthcare providers and stakeholders through various dissemination activities, including workshops and presentations within relevant TCM and stroke management networks. …”
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50193
Probiotic Bacillus pumilus LV149 enhances gut repair, modulates microbiota, and alters transcriptome in DSS-induced colitis mice
Published 2025-01-01“…The effects were assessed through physiological parameters, intestinal barrier integrity, inflammation, gut microbiota composition, and transcriptomic changes.ResultsLV149 significantly improved pathological symptoms, including weight loss and disease activity index (DAI), and reduced colon shortening in a dose-dependent manner and inflammatory damage. …”
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50194
Combined application of chemical and organic fertilizers enhances soil organic carbon sequestration and crop productivity by improving carbon stability and management index in a ri...
Published 2025-01-01“…Conversely, it showed the lowest OC values in the labile fraction and active pool compared to CK, NPK, and 2NPK treatments. …”
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50195
Rigidez arterial e atividade física no lazer em agentes comunitárias de saúde: um estudo transversal
Published 2024-09-01“…A AFL foi avaliada pela versão longa do International Physical Activity Questionnaire e a RA foi mensurada pela Velocidade de Onda de Pulso carotídeo-femoral (VOPc-f ). …”
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50196
Factors associated with risk of sarcopenia in older adults
Published 2021-05-01“…Utilizaram-se como instrumento os questionários sociodemográficos, o International Physical Activity Questionnaire (IPAQ) e o SARC-f. A análise dos dados foi realizada pelo teste do qui-quadrado e pela regressão logística binária (p < 0,05). …”
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50197
Co-creating a person-centered creative engagement intervention for Parkinson's care
Published 2025-01-01“…Participants chose from multiple media and autonomously decided their creative activities. Guidance from the creative therapists was provided as needed to support individual engagement and guide reflection and learning processes. …”
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50198
Bacteria-specific modified nucleoside is released and elevated in urine of patients with bacterial infections
Published 2025-01-01“…Under normal culture conditions, bacteria did not actively release most modified nucleoside species, but robustly released nucleosides, including m2A, following addition of antibiotics or immune cells. …”
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50199
A European aerosol phenomenology – 9: Light absorption properties of carbonaceous aerosol particles across surface Europe
Published 2025-01-01“…Diel cycles of bAbs,BC peaked during morning and evening rush hours, whereas bAbs,BrC, %AbsBrC, AAE, and AAEBrC peaked at night when emissions from household activities accumulated. Decade-long trends analyses demonstrated a decrease in bAbs, due to reduction of BC emissions, while bAbs,BrC and AAE increased, suggesting a shift in CA composition, with a relative increase in BrC over BC. …”
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50200
Longitudinal immunogenicity cohort study of SARS-CoV-2 mRNA vaccines across individuals with different immunocompromising conditions: heterogeneity in the immune response and cruci...
Published 2025-03-01“…Interpretation: Our study highlights the heterogeneous immune response across individuals with different pathologies, the pivotal role of the first booster dose, the primary activation of Omicron-specific B cells elicited by updated variant-adapted vaccines and the persistence of low-responders despite multiple vaccine administrations. …”
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