Within- and between-day test–retest reliability of responses to rapid bilateral anterolateral magnetic phrenic nerve stimulation in healthy humans (ReStim) by Kyle G. P. J. M. Boyle, Andrea A. Beglinger, Heinrich Häusler, Anna Stahel, Esther I. Schwarz, Esther I. Schwarz, Christina M. Spengler, Christina M. Spengler

“…Rapid bilateral anterolateral magnetic phrenic nerve stimulation (rBAMPS) may attenuate both of the aforementioned issues by inducing diaphragm activation. However, in order for rBAMPS to become part of standard of care, the reliability of inspiratory responses to rBAMPS needs to be established.MethodsEighteen healthy participants (9F) underwent five blocks of 1-s rBAMPS at 25 Hz starting at 20% of maximal stimulator output with 10% increments. …”
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Micro-Credit Institutions’ Services and Sustainability of Micro, Small and Medium-Scale Enterprises During Covid-19 Pandemic in Kigezi Region, South Western Uganda. by Agaba, Moses, Kaaya, Siraj, Nafiu, Lukman Abiodun

“…Enterprise owners and managers were the units of inquiry due to their importance as custodians of information on all the activities taking place in their respective MSMEs (Rhodes, 2009). …”
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[^99mTc]Technetium and Rhenium Dithiocarbazate Complexes: Chemical Synthesis and Biological Assessment by André Gustavo de Araujo Fernandes, Alyne Eloise Lafratta, Carolina Portela Luz, Debora Levy, Daniele de Paula Faria, Carlos Alberto Buchpiguel, Ulrich Abram, Victor Marcelo Deflon, Fabio Luiz Navarro Marques

“…Background/Objectives: Dithiocarbazates (DTCs) and their metal complexes have been studied regarding their property as anticancer activities. In this work, using S-benzyl-5-hydroxy-3-methyl-5-phenyl-4,5-dihydro-1H-pirazol-1-carbodithionate (H₂bdtc), we prepared [ReO(bdtc)(Hbdtc)] and [[^99mTc]TcO(bdtc)(Hbdtc)] complexes for tumor uptake and animal biodistribution studies. …”
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Dihydroquercetin attenuated Prevotella copri-caused intestinal injury by modulating gut microbiota and bile acids in weaned piglets by Long Wang, Ruizhi Hu, Siqi Ma, Xizi Yang, Jiatai Gong, Hongkun Xiang, Mingkun Shi, Xupeng Yuan, Liang Chen, Hongfu Zhang, Bie Tan, Xi He, Jianhua He, Shusong Wu

“…Results showed that P. copri decreased significantly the average daily gain (ADG) (P < 0.001), which was recovered by supplementation of DHQ with decreased serum levels of malondialdehyde (MDA), interleukin (IL)-2 and IL-8 but increased total superoxide dismutase (T-SOD) activity and IL-10 in weaned piglets (P < 0.001). Moreover, DHQ increased the expression of tight junction proteins (claudin-2, occludin and tight junction protein zonula occludens protein-1 (ZO-1) and the mRNA expression of glutathione peroxidase 4 (GPX-4) in ileum (P < 0.001). …”
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Causally inferred evidence of the impact of green and blue spaces (GBS) on maternal and neonatal health: a systematic review and meta-analysis by Rukun K S Khalaf, Selin Akaraci, Faye D Baldwin, Rebecca S Geary, Ruwanthi Kolamunnage-Dona, Ruth F Hunter, Sarah E Rodgers

“…Extensive GBS research into health supports the theory that GBS promotes physical activity and has mental restorative and environmental mitigative properties. …”
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Phase 1, open-label, dose-escalation study on the safety, pharmacokinetics, and preliminary efficacy of intravenous Coxsackievirus A21 (V937), with or without pembrolizumab, in pat... by Christy Ralph, Sumati Gupta, Matthew Zibelman, Brendan D Curti, Kevin J Harrington, Steven J O'Day, Andrew G Hill, David C Campbell, Gavin M Wright, David E Gerber, Jonathan E Rosenberg, Jaime R Merchan, Charles M Rudin, Hardev S Pandha, Wallace L Akerley, Daphne Day, Timothy D Clay, Ross R Jennens, Yixin Ren, Emmett V Schmidt, Lisa Guttman

“…Background Oncolytic virus V937 showed activity and safety with intratumoral administration. …”
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Functional status, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio as prognostic factors of one-year survival rate in elderly patients with advanced-stage non-small... by Ratna Nurhayati, Aulia Rizka, Cleopas Martin Rumende, Noorwati Sutandyo, Arif Hanafi, Edy Rizal Wahyudi, Hamzah Shatri, Anna Mira Lubis, Em Yunir, Muhammad Firdaus, Yuniar Harris Prayitno, Nadira Nibras Taqiyya

“…Medical records were collected, comprising complete blood count prior to chemotherapy or radiotherapy, assessment of functional status through the Barthel Index for Activities of Daily Living (ADL), and 1-year survival post-diagnosis. …”
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CAM/TMA-DPH as a promising alternative to SYTO9/PI for cell viability assessment in bacterial biofilms by Tinatini Tchatchiashvili, Tinatini Tchatchiashvili, Mateusz Jundzill, Mateusz Jundzill, Mike Marquet, Kamran A. Mirza, Kamran A. Mirza, Mathias W. Pletz, Mathias W. Pletz, Oliwia Makarewicz, Oliwia Makarewicz, Lara Thieme, Lara Thieme

“…To address this limitation, we investigated an alternative staining method employing calcein acetoxymethyl (CAM) to detect viable cells based on esterase activity, and 1-(4-trimethylammoniumphenyl)-6-phenyl-1,3,5-hexatriene p-toluenesulfonate (TMA-DPH) to assess the remaining biofilm population.MethodsBiofilms of Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, and Enterococcus faecium were matured and exposed to varying concentrations of antibiotics or sterile medium. …”
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Wu-Mei-Wan enhances brown adipose tissue function and white adipose browning in obese mice via upregulation of HSF1 by Shen Chen, Kexin Nie, Hongzhan Wang, Yang Gao, Xinyue Jiang, Hao Su, Zhi Wang, Yueheng Tang, Fuer Lu, Hui Dong, Jingbin Li

“…Brown adipose tissue (BAT) activity was evaluated using Positron Emission Tomography, and ultrastructural changes were examined via transmission electron microscopy. …”
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Core microbe Bifidobacterium in the hindgut of calves improves the growth phenotype of young hosts by regulating microbial functions and host metabolism by Yimin Zhuang, Duo Gao, Wen Jiang, Yiming Xu, Guanglei Liu, Guobin Hou, Tianyu Chen, Shangru Li, Siyuan Zhang, Shuai Liu, Jingjun Wang, Jianxin Xiao, Mengmeng Li, Wei Wang, Shengli Li, Zhijun Cao

“…Furthermore, pathways involved in carbohydrate degradation, glycolysis, and biosynthesis of propionate and proteins were active, while methane production was inhibited. In addition, the diversity and richness of hindgut resistome in cluster2 were lower than those in cluster1. …”
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Effect of straw retention and mineral fertilization on P speciation and P-transformation microorganisms in water- extractable colloids of a Vertisol by S. Bai, S. Bai, Y. Ge, D. Yao, Y. Wang, J. Tan, J. Tan, S. Zhang, Y. Peng, X. Jiang

“…In bulk soil, mineral fertilization led to increases in the levels of total P, available P, acid phosphatase (ACP), high-activity inorganic P fractions (Ca<span class="inline-formula">₂</span>-P, Ca<span class="inline-formula">₈</span>-P, Al-P, and Fe-P), and organic P (orthophosphate monoesters and orthophosphate diesters) but significantly decreased the abundances of P-cycling genes including P mineralization, P-starvation response regulation, and P uptake and transport by decreasing soil pH and increasing total P. …”
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Potential Mechanisms and Effects of Dai Bai Jie Ethanol Extract in Preventing Acute Alcoholic Liver Injury by Niantong Xia, Hongwei Xue, Yihang Li, Jia Liu, Yang Lou, Shuyang Li, Yutian Wang, Juan Lu, Xi Chen

“…DBJ-3 reduced malondialdehyde (MDA), reactive oxygen species (ROS), and inflammatory factors, such as tumor necrosis factor (TNF-α), interleukin-1β (IL-1β), and interleukin 6 (IL-6), while increasing superoxide dismutase (SOD) and glutathione S-transferase (GST) activities. Furthermore, DBJ-3 significantly increased alcohol dehydrogenase 1b (ADH1B) and aldehyde dehydrogenase 2 (ALDH2) expression at the gene and protein levels within alcohol metabolism pathways and reduced the nuclear factor kappa-B (NF-κB) gene and protein levels. …”
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Loop33 × 123 CAR-T targeting CD33 and CD123 against immune escape in acute myeloid leukemia by Haotian Ma, Zhifeng Yan, Runxia Gu, Yingxi Xu, Shaowei Qiu, Haiyan Xing, Kejing Tang, Zheng Tian, Qing Rao, Min Wang, Jianxiang Wang

“…Phenotype detection was evaluated on day 7 concerning activation, exhaustion, and subtype proportions. Coculture killing assays were conducted using various AML cell lines and primary AML cells. …”
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Impact of microwave processing on phytochemicals, antioxidant status, anti-nutritional factors and metabolite profile of maize flour by Alla Yaswanth Naveen Kumar, Alonkrita Chowdhury, Rajesh Kumar, Vivek Kumar Maurya, Subhasis Batabyal, Mayukh Ghosh

“…Total phenolics (947.95–1304.77 µg GAE/g) and flavonoids (482.73–916.82 µg QE/g) varied, with flavonol content increasing (6.59–43.35 µg CE/g) and soluble sugar content decreasing (6563.13–15,578.75 µg DE/g) compared to the control. Antioxidant activities, such as ABTS scavenging (360.45–638.92 µg GAE/g), total antioxidant capacity (1888.38–2250.54 µg AAE/g), and cupric-reducing capacity (1008.64–2004.09 µg AAE/g), showed treatment-specific variations. …”
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Balancing environmental impact: A sustainability index analysis of sorghum production for food and feed by A. Prabowo, R.N. Hayati, S. Minarsih, B. Haryanto, D.D. Ludfiani, A. Supriyo, S. Subiharta, E. Nurwahyuni, Y. Hindarwati, M.N. Setiapermas, S. Sudarto, S. Samijan, B. Utomo, E. Winarn, N.D. Suretno, W. Wibawa, S. Agustini, A. Prasetyo, F.R.P. Hantoro, W. Hariyanto, V.E. Aristya

“…These included land availability, the efficiency of water used, the prevention of natural resource exploitation, motivation level, minimal interference with primary agricultural activities, community acceptance, productivity, sales profit level, ease of sale and cultivation, tools availability, and technological sensitivity.CONCLUSION: Sustainability index of sorghum for food and feed was categorized as very sustainable with a value of 79.67. …”
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Spatiotemporal discrepancies and risk assessment of toxic heavy metals in surface water of Shitalakhya River around Narayanganj port in Bangladesh by Shahrina Sultana, Md. Sirajul Islam, Md. Humayun Kabir, Rima Sarker, Tanmoy Roy Tusher, Mir Md. Mozammal Hoque, Nowara Tamanna Meghla

“…The results confirmed the spatiotemporal discrepancies in toxic metal concentrations and associated ecological and human health risks, possibly resulting from the hydrological and anthropogenic interventions not only associated with port activities. Hence, urgent collective effort and proper monitoring are of utmost importance to safeguard the public health and this urban riverine ecosystem.…”
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Dose effects of iron on growth, antioxidant potential, intestinal morphology, and intestinal barrier in yellow-feathered broilers by J. Chen, K.W. Lei, S.Y. Li, D.P. Li, Y.L. Wang, X. Wang, X. Bai, Y.L. Huang

“…A quadratic response was found for jejunal diamine oxidase (DAO) activity (P = 0.011) as dietary Fe supplementation was increased. …”
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Impairment of myocardial perfusion correlates with heart failure severity in patients with non‐compaction cardiomyopathy by Andraz Cerar, Martina Jaklic, Sabina Frljak, Gregor Poglajen, Gregor Zemljic, Barbara Guzic Salobir, Maja Dolenc Novak, Monika Stalc, Rok Zbacnik, Mirta Kozelj

“…Conclusions The presence of myocardial ischemia in patients with NCM is associated with worse left ventricular function, dilation of the left ventricle, and more pronounced neurohumoral activation.…”
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Effects of prolonged NaHCO3 exposure on the serum immune function, antioxidant capacity, intestinal tight junctions, microbiota, mitochondria, and autophagy in crucian carp (Carass... by Jia Liu, Faye Zhang, Zihao Yan, Zhengyao Guo, Yuqian Lu, Baolan Yao, Yuehong Li, Wenfa Lv

“…The mitochondrial membrane potential and the activities of ATPase were significantly decreased, leading to mitochondria dysfunction. …”
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Revealing the biological features of the axolotl pancreas as a new research model by Hui Ma, Hui Ma, Hui Ma, Guangcong Peng, Yan Hu, Binbin Lu, Binbin Lu, Yiying Zheng, Yingxian Wu, Weimin Feng, Yu Shi, Xiangyu Pan, Li Song, Ina Stützer, Yanmei Liu, Jifeng Fei, Jifeng Fei, Jifeng Fei

“…Notably, the adult axolotl pancreas exhibits slower metabolic activity compared to mammals, as evidenced by the results of GTT and ITT. …”
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