uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease by Yu Shen, Kaiyan Jiang, Dandan Tan, Min Zhu, Yusen Qiu, Pencheng Huang, Wenquan Zou, Jianwen Deng, Zhaoxia Wang, Ying Xiong, Daojun Hong

“…Additionally, the therapeutic potential of NF-κB activators was evaluated in a Drosophila model with a CGG expansion knock-in. …”
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INTERNATIONAL AND NATIONAL LEGAL MECHANISMS OF JUDICIAL LIABILITY IN THE CONDITIONS OF ECONOMIC GLOBALISATION OF MODERN SOCIETY by Konul Akhundova

“…Within the framework of the national legal systems of the countries under consideration, the features of holding judges accountable in relation to their professional activities and for offences committed outside them are determined, which mediate the implementation of the content of the immunity and immunity of such officials. …”
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Hydrogen-oxygen mixture inhalation as an adjunctive treatment to home-based exercise in older patients with knee osteoarthritis: an open-label, blinded-endpoint, randomized control... by Chenhui Wang, Mengwei Yan, Yuru Li, Lei Han, Hongqian Wang, Shufeng Jia, Xingchen Liu, Yang Liu, Fan Wu, Baoguo Wang

“…No significant differences were observed between both groups at week 12 in CST, TUG, SF-36 scores, EARS scores, or the incidence of adverse events.ConclusionAlthough clinical significance was not achieved, H2-O2 inhalation alleviated KOA symptoms and enhanced functional activity in elderly patients undergoing the HBE program during the initial 2 weeks. …”
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Formulating a Blue Ocean Strategy in the Banking Services Industry: Enhancing Customer Satisfaction through Improved Demand Fulfillment and Presenting an Optimal Pattern by Manuchehr Ghanbari, Ali Sabzali Yameqani, Yousef Rabbani, Kobra Sabzali Yamaqani

“…Maintaining physical banking communications alongside virtual communications and limiting the scope of bank activity on specific fields are the least important actions related to customer needs. …”
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A Zinc Polyphenolic Compound Increases Maize Resistance Against Infection by <i>Bipolaris maydis</i> by Luis Felipe Lata-Tenesaca, Marcos José Barbosa Oliveira, Aline Vieira Barros, Leandro Castro Silva, João Américo Wordell Filho, Fabrício Ávila Rodrigues

“…For infected and IR-stimulus-sprayed plants, the glucose, fructose, sucrose, and starch concentrations were significantly higher compared to inoculated plants from the control treatment. The activity levels of superoxide dismutase, ascorbate peroxidase, catalase, and glutathione reductase were significantly higher for the IR-stimulus-sprayed plants compared to plants from the control treatment. …”
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Performance of zero water discharge (ZWD) system with nitrifying bacteria Bacillus megaterium and microalgae Chaetoceros calcitrans components in super intensive pacific white shri... by Rahim Rahim, Gede Suantika, Harish Muhammad

“…This study consisted of four steps, (1) activation and cultivation of nitrifying bacteria, microalgae C. calcitrans and B. megaterium; (2) acclimatization of Pacific white shrimp PL10 with 30 g/L of salinity and decreasing salinity at 2–3 g/L/day; (3) conditioning of ZWD system; (4) white shrimp rearing in 400 L of tank for ten weeks. …”
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The palmitoyl-CoA ligase Fum16 is part of a Fusarium verticillioides fumonisin subcluster involved in self-protection by Fabio Gherlone, Katarina Jojić, Ying Huang, Sandra Hoefgen, Vito Valiante, Slavica Janevska

“…These findings enhance our understanding of mycotoxin self-protection mechanisms and could inform strategies for predicting biological activity of unknown secondary metabolites, managing mycotoxin contamination, and developing resistant crop cultivars.…”
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Outcome and Management of Sepsis at RozhHalat Emergency Hospital in Erbil –Kurdistan region of Iraq by Samir Qader Ahmad, Shakawan Muhamad Ismaeel, Dara Ahmed Mohammed Ahmed Mohammed, Halgurd Fathulla Ahmed

“…Sepsis is a complex condition characterized by activation of inflammatory process and coagulation system in response to microbial insult. …”
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MATERIAL BANGUNAN RUMAH TINGGAL SEBAGAI KETAHANAN RESIKO COVID-19: STUDI KASUS RUMAH TINGGAL DI KECAMATAN MENGANTI, KABUPATEN GRESIK, JAWA TIMUR by Heristama Anugerah Putra, Brina Oktafiana

“…Moreover, PKKM status has been abolished and gives residents freedom to do their activities inside or outside the room. The main objective of this study is to investigate the impact of material selection on passive cooling in residential buildings in response to the risk of Covid-19. …”
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O-GlcNAcylation attenuates ischemia-reperfusion-induced pulmonary epithelial cell ferroptosis via the Nrf2/G6PDH pathway by Liuqing Yang, Hexiao Tang, Jin Wang, Dawei Xu, Rui Xuan, Songping Xie, Pengfei Xu, Xinyi Li

“…Furthermore, both the chromatin immunoprecipitation (ChIP) assay and the dual-luciferase reporter assay indicated that Nrf2 could bind with translation start site (TSS) of glucose-6-phosphate dehydrogenase (G6PDH) and promote its transcriptional activity. As an important rate-limiting enzyme in the pentose phosphate pathway (PPP), elevated G6PDH provided a mass of nicotinamide adenine dinucleotide phosphate (NADPH) to improve the redox state of glutathione (GSH) and eventually led to ferroptosis resistance. …”
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Crystalloid resuscitation is associated with decreased treatment delays and improved systolic blood pressures in a blood-constrained setting by Melissa Carvalho, Alain Chichom-Mefire, Catherine Juillard, S Ariane Christie, Rasheedat Oke, Thompson Kinge, Jean-Gustave Tsiagadigui, Mbiarikai A Mbianyor, Mark T Yost, Matt Driban, Fanny Nadia Dissak Delon, Richard Njock, Daniel Nkusu

“…Patients presenting with hemorrhagic shock (systolic blood pressure (SBP) &lt;100 mm Hg and active bleeding) were categorized as receiving CB, BL, or no resuscitation (NR). …”
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CEST imaging combined with 1H-MRS reveal the neuroprotective effects of riluzole by improving neurotransmitter imbalances in Alzheimer’s disease mice by Yuanyu Shen, Xiaolei Zhang, Siqi Liu, Lijing Xin, Wentao Xuan, Caiyu Zhuang, Yue Chen, Beibei Chen, Xinhui Zheng, Renhua Wu, Yan Lin

“…Immunohistochemistry and Nissl staining demonstrated that riluzole treatment reduced amyloid-beta (Aβ) deposition, tau hyperphosphorylation, GFAP-positive astrocyte activation, and prevented neuronal loss. Moreover, riluzole upregulated the expression of excitatory amino acid transporter 2 (EAAT2), glutamic acid decarboxylase 65/67 (GAD65/67), and glutamine synthetase (GS), suggesting enhanced neurotransmitter metabolism. …”
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The Policy and Governance Observatory as a Facilitator of Smart and Evidence-based Governance by Atiye Yousefi, Mahdi Abdolhamid

“…In order to address this issue, the present article has done a comprehensive review of the most well-known observatories active in the field of policy making and public and topical governance around the world.…”
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Development of an Alternative Protocol to Study Muscle Fatigue by Daniela A. Alambarrio, Benjamin K. Morris, R. Benjamin Davis, Emily B. Grabarczyk, Kari K. Turner, John M. Gonzalez

“…The data indicated that EMS is a valuable tool for replicating ambulatory movement or physical activity, but super-contraction is not a means to accelerate postmortem muscle fatigue onset. …”
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Room temperature self-assembly and nonenzymatic electrochemical sensing performance of transition metal-embedded wheel-shaped tungstophosphates by Wen-Da Liu, Hao-Tian Zhu, Xue Zhang, Fang Su, Xiao-Jing Sang, Xiao-Lan Zhang, Lan-Cui Zhang

“…Compared with K28Li5[H7P8W48O184]·92H2O without 3d-TM and most reported POM electrode materials, the proposed 3d-TM-{P8W48} POMs exhibited higher stability and better activity during H2O2 detection. Composite films formed using 1–3 and chitosan (CS) on a glassy carbon electrode exhibited a high sensitivity (1.21 μA∙mmol∙L−1), low detection limit (0.02 mmol∙L−1), and rapid response time (2 s) for H2O2 detection. …”
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Relationships between paddock-level pasture mass and cow data derived from GPS and behavior-monitoring on-animal sensors in rotationally grazed dairy systems by S.J. Hendriks, M. Qasim, J.P. Edwards

“…Each cow was fitted with 5 devices that were commercially available in New Zealand and measured rumination, eating, grazing, and lying time, and activity. One device also determined cows' location, and these data were used to derive 3 additional behaviors: distance traveled, mean distance to herd mates, and proximity. …”
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Efficacy and Safety of Pramipexole Sustained Release versus Immediate Release Formulation for Nocturnal Symptoms in Chinese Patients with Advanced Parkinson’s Disease: A Pilot Stud... by Haiyan Zhou, Shuhua Li, Hongmei Yu, Shenggang Sun, Xinhua Wan, Xiaodong Zhu, Chun-Feng Liu, Ling Chen, Wei Xiang, Yaqing Sun, Haibo Chen, Shengdi Chen

“…SUSTAIN was an open-label, randomised, active-controlled parallel group exploratory pilot study (NCT03521635). …”
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Spatiotemporal variation in biomass abundance of different algal species in Lake Hulun using machine learning and Sentinel-3 images by Zhaojiang Yan, Chong Fang, Kaishan Song, Xiangyu Wang, Zhidan Wen, Yingxin Shang, Hui Tao, Yunfeng Lyu

“…Abstract Climate change and human activities affect the biomass of different algal and the succession of dominant species. …”
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Causes and determinants of infant mortality using verbal autopsy and social autopsy methods in a rural population of Odisha: a community-based matched case-control study by Amit Kumar Satapathy, Arvind Kumar Singh, Priyamadhaba Behera, Debkumar Pal, Abhisek Mishra

“…The cause of infant deaths should be assessed in both medical and social contexts.Objectives We aimed to determine the medical causes of infant mortality by verbal autopsy and its determinants in two rural blocks of the Khordha district of Odisha and assess the pathway of care and delay in seeking care for the illness preceding infant death using the three-delay model.Design We conducted this community-based matched case-control study to identify the medical causes of infant mortality using the verbal autopsy method along with the identification of delay and pathway of care related to infant deaths using a social autopsy method.Settings Two rural blocks of Odisha, India.Participants We enumerated 100 infant deaths by active surveillance and data triangulation from Accredited Social Health Activists, Auxiliary Nurse Midwives and block-level health information systems. …”
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Association between oxidative balance scores and peripheral artery disease in US adults: a cross-sectional study by Min Zhou, Min Zhou, Peng-Fei He, Peng-Fei He, Keren Zhang, Li-Juan Deng, Ning Wang, Gang Wang, Guang-Yao Yang, Shang Ju

“…BackgroundThe Oxidative Balance Score (OBS) quantifies the overall oxidative stress burden, with higher scores indicating greater antioxidant (relative to prooxidant) activity. This study aimed to examine the association between peripheral arterial disease (PAD) and OBS.Methods and materialsData from the National Health and Nutrition Examination Survey (NHANES, 1999–2004) were analyzed for participants with ankle-brachial index (ABI) measurements. …”
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