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49961
Comparative evaluation of antifungal susceptibility testing methods of invasive Candida species and detection of FKS genes mutations in caspofungin intermediate and resistant isola...
Published 2025-01-01“…Conclusions ATB FUNGUS 3 demonstrated acceptable performance for AFST, however, azole activity against Candida spp. should be interpreted carefully. …”
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49962
Mathematical modelling-based blockchain with attention deep learning model for cybersecurity in IoT-consumer electronics
Published 2025-02-01“…Prepared with sophisticated sensors and onboard processing abilities, these drones autonomously examine aerial imagery to identify and classify possible risks like suspicious activities, unauthorized personnel, or vehicles. DL approaches allow drones to learn complex patterns and anomalies in real-time, enabling quick response and proactive security procedures. …”
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49963
The relevance of a multidomain geriatric assessment in older patients with heart failure
Published 2020-06-01“…The following geriatric domains were assessed: physical function, nutrition, polypharmacy, cognition, and dependency in activities of daily living. Logistic regression analyses adjusted for age, sex, diabetes and kidney function assessed 3 month risk of adverse health outcomes (emergency department visits, hospital admissions, and/or death) according to HF severity, physical frailty, and number of affected domains. …”
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49964
Inflammatory Indices and MAFLD Prevalence in Hypertensive Patients: A Large-Scale Cross-Sectional Analysis from China
Published 2025-02-01“…Di Shen,1,* Xintian Cai,2,* Junli Hu,2 Shuaiwei Song,1 Qing Zhu,2 Huimin Ma,2 Yingying Zhang,2 Rui Ma,2 Pan Zhou,2 Wenbo Yang,2 Jing Hong,2 Delian Zhang,2 Nanfang Li2 1Graduate School, Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region, Hypertension Research Laboratory, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, Urumqi, Xinjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Nanfang Li, Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region “Hypertension Research Laboratory”, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, No. 91 Tianchi Road, Urumuqi, Xinjiang, 830001, People’s Republic of China, Tel +86 8564818, Email lnanfang2016@sina.comObjective: Hypertension development and progression are largely influenced by inflammation, which plays a critical role by activating the immune system and causing damage to the vascular endothelium. …”
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49965
RETRACTED: Long non‐coding RNA Sox2OT promotes coronary microembolization‐induced myocardial injury by mediating pyroptosis
Published 2022-06-01“…Results Rat CME disrupted the cardiac functions and induced inflammatory responses and oxidative stress, and activated the nuclear factor‐kappa B (NF‐κB) pathway and pyroptosis (all P < 0.05). …”
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49966
Evaluating the Efficacy of a Serious Game to Deliver Health Education About Invasive Meningococcal Disease: Clustered Randomized Controlled Equivalence Trial
Published 2025-02-01“…The findings were compared with changes in an active control (comparison) group who received an in-class educational presentation about IMD transmission and protection. …”
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49967
Identification of a novel disulfidptosis-related gene signature in osteoarthritis using bioinformatics analysis and experimental validation
Published 2025-01-01“…ZNF484 and NDUFS1 were found to be significantly overexpressed in subtype 1, while the infiltration abundance of activated mast cells was markedly elevated in subtype 2. …”
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49968
Polish Historiography of Polish - Lithuanian Union of 20th Century
Published 1998-12-01“…There were no big debates on the reasons for the Lublin union: growing political activity of the Lithuanian nobility and its attempts to have equal rights with the Polish nobility, war between Lithuania and Moscow, and hope for the Polish nobility to realize old state rights, i.e., "executional attempt," and finally, the dominance and attractiveness of Polish culture. …”
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49969
TIGIT inhibitor M6223 as monotherapy or in combination with bintrafusp alfa in patients with advanced solid tumors: a first-in-human, phase 1, dose-escalation trial
Published 2025-02-01“…Additional objectives included pharmacokinetics, pharmacodynamics and clinical activity (NCT04457778).Results Two dose-limiting toxicities were observed: grade 3 adrenal insufficiency (Part 1A: M6223 900 mg every 2 weeks) and grade 3 anemia (Part 1B: M6223 300 mg, only BA related). …”
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49970
Mapping mycological ignorance – checklists and diversity patterns of fungi known for West Africa
Published 2020-07-01“…Recent opportunistic sampling activities in Benin showed that it is not difficult to find specimens representing new country records. …”
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49971
Improving machine learning predictions to estimate fishing effort using vessel's tracking data
Published 2025-03-01“…To effectively monitor SSF activities and their ecological impacts, it is required precise estimation of fishing effort using high-resolution spatio-temporal data. …”
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49972
The Prevalence of Depression Among Parkinson’s Disease Patients in Saudi Arabia: A Cross-Sectional Study
Published 2025-02-01“…Those unable to perform daily living activities or who faced stigma had a 16.5 times higher likelihood of anxiety symptoms [OR = 16.5, 95% CI (1.62– 168.48), p = 0.018]. …”
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49973
Integrating rapamycin with novel PI3K/Akt/mTOR inhibitor microRNAs on NOTCH1-driven T-cell acute lymphoblastic leukemia (T-ALL)
Published 2024-07-01“…Rapamycin is a potential therapeutic strategy for hematological malignancies due to its ability to suppress mTOR activity. Additionally, microRNAs (miRNAs) have emerged as key regulators in T-ALL pathophysiology and treatment. …”
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49974
Life cycle assessment of coconut plantation, copra, and charcoal production
Published 2023-10-01“…Normalization results showed that the category with enormous impacts on humans from coconut cultivation and copra processing activities had terrestrial ecotoxicity potential. The largest impact on charcoal production was on the human toxicity potential. …”
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49975
Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms
Published 2025-01-01“…Results: Cadmium (Cd) exposure caused anemia and hepatorenal damage, as evidenced by increased serum levels of urea, creatinine, uric acid, total bilirubin (including its direct and indirect fractions), and elevated activities of liver enzymes such as alanine transaminase (ALT), aspartate transaminase (AST), and alkaline phosphatase (ALP). …”
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49976
A relay race of ESCRT-III paralogs drives cell division in a hyperthermophilic archaeon
Published 2025-02-01“…Our data suggest that ESCRT-III plays an active role during the early stage of membrane constriction during cytokinesis, whereas ESCRT-III-1 and ESCRT-III-2 are indispensable for the “pre-late” and “late” stages of cytokinesis, respectively. …”
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49977
Designing and Modeling Digital Transformation in the Automotive Industry: Leveraging the Fourth Industrial Revolution
Published 2024-04-01“…To get familiar with the depth and scope of the content of the data, repeated and active reading of the data (searching for meanings and patterns) were done. …”
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49978
MODIFICATION OF STUDENT ASSESSMENT CRITERIA AS A CONDITION OF MOTIVATION INCREASING FOR PHYSICAL EDUCATION LESSONS
Published 2016-01-01“…However, there is an obvious tendency of interest decrease of school students to occupations by physical culture and their extremely low physical activity that is reflected on health of younger generation. …”
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49979
Health-Related Quality of Life in Patients with Friedreich Ataxia Using Mobility Assistive Technologies: Limited Fit of the EQ-5D-3L Mobility Dimension
Published 2024-12-01“…The mobility item correlated moderately with disease severity (r sp = 0.35) and the activities of daily living scale (r sp = 0.36) in wheelchair users. …”
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49980
Comparing Deep Learning models for mapping rice cultivation area in Bhutan using high-resolution satellite imagery
Published 2025-01-01“…To address these concerns related to food security, through various policies and implementation, the Bhutanese government is promoting several drought-resilient, high-yielding, and disease-resistant crop varieties to actively combat environmental challenges and support higher crop yields. …”
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