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49681
Jiawei Suanzaoren decoction for the treatment of perimenopausal insomnia: clinical observation and experimental study
Published 2025-01-01“…The results of network pharmacology indicate that in the main signaling pathways for treating insomnia, it is speculated that Jiawei Suanzaoren Tang can regulate the signaling pathway of neuroactive ligand receptor interactions by inhibiting the activation of related proteins, thereby improving sleep. …”
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49682
Spatial-Temporal Changes and Influencing Factors of Regional Technological Innovation Efficiency in China: A Three Entity Comparative Perspective
Published 2025-01-01“…The reason for the insignificant effect of enterprise-research institute collaborative innovation on research institutes' efficiency may be that both research institutes and firms consider technological application and development as the main goal of collaborative innovation, and collaborative innovation with firms crowds out the internal innovation resources of research institutes and inhibits their technological innovation activities. We contribute to the literature on regional innovation systems by comparing the differences in the technological innovation efficiency of the main innovation entities in the regional innovation systems of a transition economy. …”
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49683
PENGEMBANGAN MODUL SUHU DAN KALOR DENGAN PENDEKATAN SAINTIFIK UNTUK MELATIHKAN LITERASI SAINS PESERTA DIDIK DI SMA
Published 2022-01-01“…This is an expert validation sheet that contains material aspects, aspects of module characteristics, language aspects and media aspects, while the module characteristics are developed, there is a scientific approach to the concepts and independent activity sheets, there are theoretical questions, calculation questions and scientific literacy questions to practice the ability of students. …”
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49684
Effects of cold-pressed wheat germ oil and Bacillus subtilis on growth performance, digestibility, immune status, intestinal microbial enumeration, and gene expression of broilers...
Published 2025-02-01“…The CWB group also showed lower malondialdehyde and interleukin-6 levels, with higher superoxide dismutase activity, and increased levels of IgA, IgG, and interleukin-10. …”
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49685
Microplastics in beach sediments, seawater, and common fish in tourist destinations
Published 2024-10-01“…BACKGROUND AND OBJECTIVES: The global concern over microplastic pollution has been on the rise, primarily due to its detrimental effects on marine ecosystems and the potential health risks it poses to humans. Tourism activities are the main sources of plastic waste that deteriorates into microplastics. …”
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49686
Interaction of genetics risk score and fatty acids quality indices on healthy and unhealthy obesity phenotype
Published 2025-01-01“…Results We found significant interactions between GRS and N6/N3 in the adjusted model controlling for confounding factors (age, body mass index, energy, and physical activity) (β = 2.26, 95% CI: 0.008 to 4.52, P = 0.049). …”
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49687
The Effects of High Particulate Matter Levels on Platelet Recovery in Patients Receiving Prophylactic Platelet Transfusion
Published 2025-02-01“…Sasinee Hantrakool,1 Maitree Sriwichai,2 Banphot Shaengkhamnang,2 Nipapan Leetrakool,2 Piangrawee Niprapan,1 Sawaeng Kawichai,3 Teerachat Punnachet,1 Nonthakorn Hantrakun,1 Pokpong Piriyakhuntorn,1 Thanawat Rattanathammethee,1 Chatree Chai-Adisaksopha,1 Ekarat Rattarittamrong,1 Adisak Tantiworawit,1 Lalita Norasetthada,1 Somdet Srichairatanakool4 1Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 2Blood Bank Section, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 3Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; 4Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, ThailandCorrespondence: Chatree Chai-Adisaksopha, Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand, Tel +66 53 935488, Email chatree.chai@cmu.ac.thAim: Exposure to fine particulate matter, particularly PM2.5, has been associated with increased platelet activation and cardiovascular risks. However, its effect on platelet recovery after transfusion remains unclear.Purpose: This study aims to assess the influence of PM2.5 exposure on platelet recovery in patients with hematologic malignancies receiving prophylactic platelet transfusions.Patients and Methods: We conducted a cross-sectional study involving 66 patients with hematologic malignancies who developed chemotherapy-induced thrombocytopenia and received prophylactic platelet transfusions between January and December 2021. …”
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49688
Heavy metals contamination in geothermal medicinal plant extract; Chromolaena odorata Linn
Published 2023-10-01“…Cadmium was observed in almost all samples with a concentration range of 0.0219 ± 0.005–1.1472 ± 0.006 milligram per kilogram, which exceeded the maximum threshold (0.3 milligram per liter).CONCLUSION: Heavy metal contamination in the ethanolic extract of geothermal Chromolaena odorata leaves has been attributed to volcanic activities. Among the heavy metals of concern, cadmium was the only one with a concentration exceeding the safety limit. …”
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49689
Spectrum and trends of cancer among HIV patients in Southwestern Uganda.
Published 2025-01-01“…Participants with baseline CD4 cell count > 200 cells/μl were more than twice likely to be active in care. The Commonest ADC was Kaposi Sarcoma (KS) while the commonest NADC was Squamous cell carcinoma, Not otherwise specified. …”
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49690
Chondroitin Sulphate-Chitosan Based Nanogels Loaded with Naringenin-β-Cyclodextrin Complex as Potential Tool for the Treatment of Diabetic Retinopathy: A Formulation Study
Published 2025-01-01“…N3@NAR/β-CD capability to sustain in vitro NAR release, radical scavenging activity and in vitro biocompatibility were finally demonstrated.Conclusion: The physico-chemical properties of N3@NAR/β-CD were responsible for their cell uptake, suggesting their potential to target retinal endothelial cells. …”
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49691
The Influencers and the Adoption of New Products: Model for the Influencer Marketing
Published 2024-12-01“…Interestingly, the study noted that in some cases, followers transform from being mere recipients to active participants, taking on the role of influencers themselves. …”
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49692
The Role of Autophagy in Copper-Induced Apoptosis and Developmental Neurotoxicity in SH-SY5Y Cells
Published 2025-01-01“…Compared with the 120 μM Cu<sup>2+</sup> exposure group alone, autophagy activator rapamycin pretreatment increased expression of Wnt and β-catenin nuclear translocation, decreased expression of LC3BII/LC3BI and p62, as well as upregulated expression of Bcl2 and downregulated expressions of caspase 3 and PARP. …”
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49693
Phase I trial of hydroxychloroquine to enhance palbociclib and letrozole efficacy in ER+/HER2− breast cancer
Published 2025-01-01“…Previously, we demonstrated that low doses of palbociclib activate autophagy, reversing initial G1 cell cycle arrest, while high concentrations induce off-target senescence. …”
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49694
Pengembangan Aplikasi Sistem Penilaian Praktik Pengalaman Lapangan pada Fakultas Ilmu Komputer Universitas Brawijaya Berbasis Web
Published 2021-10-01“…However, during the FEP implementation process all activities are still carried out offline. This has the effect of limiting space and time for assessors, archiving of undermonitored assessment documents, and manipulation of assessments by students. …”
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49695
Evaluating Reaction Videos of Young People Watching Edutainment Media (MTV Shuga): Qualitative Observational Study
Published 2025-01-01“…To guide the analysis of the visual and audio data, we created a framework to examine the physical setting, group composition, social dynamics, coinciding activities, and viewers’ spoken and unspoken reactions to the show. …”
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49696
Sobre fogones y semáforos: Percepciones y analogías de dos geografías desencontradas. El caso del volcán Callaqui en la geografía ancestral pehuenche de Alto Biobío
Published 2024-08-01“…However, the Pehuenches, ancestral inhabitants of the volcano's area of influence, have lived with it in an intrinsic way for generations, and they have associated a large part of their economic, social and cultural activities with the volcano itself, giving it a protective sense from their own perceptions regarding the mountainous massif. …”
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49697
Bibliometric analysis and review of food waste management via sustainable approaches
Published 2024-10-01“…Key developments in the field include the optimization of microbial consortia for enhanced degradation and conversion efficiency, as well as the engineering of enzymes to improve specificity and activity. These advancements have led to significant improvements in the efficiency and feasibility of converting food waste into high-value products. …”
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49698
FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis
Published 2025-02-01“…It also reduced iron and MDA levels in lung tissue, increased GSH-Px activity, improved mitochondrial morphology, and enhanced the expression of GPX4 and SLC7A11, indicating its ferroptosis-inhibitory capacity. …”
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49699
Legal regime of property registration: civil-legal aspect
Published 2024-12-01“…The results of the research can be used in law-making activities to improve the current legislation in the field of registration of rights to real estate and in law enforcement when resolving disputes and implementing rights protection in the field of registration of rights to real estate.…”
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49700
UPAYA MENINGKATKAN MOTIVASI DAN HASIL BELAJAR SISWA DENGAN MODEL DISCOVERY LEARNING BERBANTUAN VIRTUAL LABORATORY
Published 2019-12-01“…Based in result of studied it was concluded that the application of Discovery Learning model assisted Virtual Laboratory can improve student learning activities, learning motivation of student and learning outcomes Keywords : Model Discovery Learning, Virtual Laboratory, Learning Motivation and Learning Outcomes …”
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