Records Keeping and Financial Performance in Local Government: A Case Study of Rubanda District Local Government. by Birungi, Edinah

“…Records management policy should be put in place to enhance records management activities within the Local Government. This can be done by policy makers so that record cycle operates on a normal scale and there is Need to have standards in place to identify best practices. …”
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Study of Acid-Base Indicator Property of the Selected Natural Food Colour Source Juice Beetroot (Beta Vulgaris), Tomato (Solanum Lycopersicon) And Carrot (Dacus Carota). by Akorabirungi, Hillary

“…A study has been done to investigate the indicator activity of aqueous extract of beetroot , carrot and tomato pigments and compared with that of already existing synthetic indicators. …”
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Records Keeping and Financial Performance in Local Government: A Case Study of Rubanda District Local Government. by Birungi, Edinah

“…Records management policy should be put in place to enhance records management activities within the Local Government. This can be done by policymakers so that the record cycle operates on a normal scale and there is a need to have standards in place to identify best practices. …”
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Child Abuse and Intention to Dropout Among Secondary School Students in Rubanda District. by Ninsiima, Patience

“…Gender-specific services and active community involvement were found critical in creating a safer learning environment. …”
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Factors Affecting the Teaching and Learning of English Language in Primary Schools in Kitumba Sub-County Kabale District. by Owomugisha, Justine

“…Provide resources and training for parents to support English learning activities at home.…”
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The Effects of Genocide on Tourism Industry in Bugesera District in Rwanda. by Egide, Mudaheranwa

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Transcriptome analysis of ovarian cancer uncovers association between tumor-related inflammation/immunity and patient outcome by Jingfang Wang, Wenrui Zhu, Xia Li, Yuanyuan Wu, Wenhui Ma, Yangzhou Wang, Weihong Zhao, Fang Wei, Wenhao Wang

“…Further analysis revealed that the high-risk group had a higher abundance of M2-type macrophage infiltration, more active anti-tumor immune response, higher tumor stemness score, potentially worse prognosis, and lower response rates to multiple chemotherapy drugs and immune checkpoint inhibitors.ConclusionThese findings provide new perspectives and potential targets for immunotherapy and prognostic evaluation of ovarian cancer and offer new strategies and directions for clinical treatment and patient management. …”
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CEERS: Increasing Scatter along the Star-forming Main Sequence Indicates Early Galaxies Form in Bursts by Justin W. Cole, Casey Papovich, Steven L. Finkelstein, Micaela B. Bagley, Mark Dickinson, Kartheik G. Iyer, L. Y. Aaron Yung, Laure Ciesla, Ricardo O. Amorín, Pablo Arrabal Haro, Rachana Bhatawdekar, Antonello Calabrò, Nikko J. Cleri, Alexander de la Vega, Avishai Dekel, Ryan Endsley, Eric Gawiser, Mauro Giavalisco, Nimish P. Hathi, Michaela Hirschmann, Benne W. Holwerda, Jeyhan S. Kartaltepe, Anton M. Koekemoer, Ray A. Lucas, Sara Mascia, Bahram Mobasher, Pablo G. Pérez-González, Giulia Rodighiero, Kaila Ronayne, Sandro Tacchella, Benjamin J. Weiner, Stephen M. Wilkins

“…These results can be explained if galaxies at higher redshift experience an increase in star formation variability and form primarily in short, active periods, followed by a lull in star formation (i.e., “napping” phases). …”
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Archaea methanogens are associated with cognitive performance through the shaping of gut microbiota, butyrate and histidine metabolism by Andrea Fumagalli, Anna Castells-Nobau, Dakshat Trivedi, Josep Garre-Olmo, Josep Puig, Rafel Ramos, Lluís Ramió-Torrentà, Vicente Pérez-Brocal, Andrés Moya, Jonathan Swann, Elena Martin-Garcia, Rafael Maldonado, José Manuel Fernández-Real, Jordi Mayneris-Perxachs

“…Phenylacetate and linoleic acid metabolism also emerged in the Aging Imageomics cohort performing untargeted HPLC-ESI-MS/MS metabolic profiling, while a targeted bile acid profiling identified again isolithocholic acid as one of the most significant bile acid increased in the HMs. 3-Methylhistidine levels were also associated with intense physical activity in a second validation cohort (IRONMET-CGM, n = 116). …”
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Inflammatory adhesion mediates myocardial segmental necroptosis induced by mixed lineage kinase domain-like protein in acute myocardial infarction by Lijiang Wei, Naifu Wan, Wentong Zhu, Chenchen Liu, Zeyu Chen, Wuwei Rong, Lujun Zhang, Meifeng Xie, Yueqi Qin, Ting Sun, Qing Jing, Ankang Lyu

“…Although existing reports indicating that mixed lineage kinase domain-like protein (MLKL) is involved in macrophage necroptosis and inflammasome activation, the downstream mechanism of MLKL in necroptosis remain poorly characterized in AMI. …”
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SNORA37/CMTR1/ELAVL1 feedback loop drives gastric cancer progression via facilitating CD44 alternative splicing by Banghe Bao, Minxiu Tian, Xiaojing Wang, Chunhui Yang, Jiaying Qu, Shunchen Zhou, Yang Cheng, Qiangsong Tong, Liduan Zheng

“…Mechanistically, as an ELAV like RNA binding protein 1 (ELAVL1)-generated snoRNA, SNORA37 directly bound to cap methyltransferase 1 (CMTR1) to facilitate its interaction with ELAVL1, resulting in nuclear retention and activity of ELAVL1 in regulating alternative splicing of CD44. …”
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Indoor and Ambient Air Pollution in Chennai, India during COVID-19 Lockdown: An Affordable Sensors Study by Naveen Puttaswamy, V. Sreekanth, Ajay Pillarisetti, Adithi R. Upadhya, Sudhakar Saidam, Balachandar Veerappan, Krishnendu Mukhopadhyay, Sankar Sambandam, Ronak Sutaria, Kalpana Balakrishnan

“…Due to COVID-19 related lockdowns, some TAPHE-2 activities were delayed; however, continuous indoor and outdoor air quality data were collected in and around Chennai, India. …”
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Biologically targeted discovery-replication scan identifies G×G interaction in relation to risk of Barrett’s esophagus and esophageal adenocarcinoma by Li Yan, Qianchuan He, Shiv P. Verma, Xu Zhang, Ann-Sophie Giel, Carlo Maj, Kathryn Graz, Elnaz Naderi, Jianhong Chen, Mourad Wagdy Ali, Puya Gharahkhani, Xiang Shu, Kenneth Offit, Pari M. Shah, Hans Gerdes, Daniela Molena, Amitabh Srivastava, Stuart MacGregor, Claire Palles, René Thieme, Michael Vieth, Ines Gockel, Thomas L. Vaughan, Johannes Schumacher, Matthew F. Buas

“…Through in silico prioritization and experimental validation, we identified a nearby proxy variant (rs4841556) as a functional modulator of enhancer activity. Enhancer-gene mapping and eQTLs implicated BLK and FAM167A as targets. …”
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Global research landscape and emerging trends of non-coding RNAs in prostate cancer: a bibliometric analysis by Yu-Liang Zhou, Yu-Liang Zhou, Wen-Liang Yao, Wen-Liang Yao, Sheng-Hui Chen, Sheng-Hui Chen, Peng Wang, Peng Wang, Jing-Wen Fu, Jing-Wen Fu, Jia-Qin Zhao, Jia-Qin Zhao, Jia-Yi Zhang, Jia-Yi Zhang

“…Fudan University was identified as the most active institution in this field. Rajvir Dahiya was the most prolific and influential author. …”
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Adaptive mechanisms to hypoxia and hyperoxia in juvenile turbot, Scophthalmus maximus by Yi Chen, Yuntian Zhang, Rongwei Zhang, Hongsheng Deng, Xiangyu Meng, Kotoya Inaba, Tatsu Osato, Xiaoran Zhao, Xiaoran Zhao, Yuzhe Han, Yuzhe Han, Tongjun Ren, Tongjun Ren

“…In hematological indicators, there are ways to help adapt to hypoxia and hyperoxia, including increased red blood cell (RBC) and hemoglobin (HGB) counts; gas and ion balance; elevated blood urea nitrogen (BUN) and malondialdehyde (MDA); increased polyphenol oxidase (PPO) and lysozyme (LZM) activity. Although turbot have adaptive mechanisms to both hypoxia and hyperoxia, extended exposure to hypoxia detrimentally affects growth, whereas hyperoxia facilitates it. …”
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Extended-spectrum β-lactamase production and antimicrobial resistance among Enterobacteriaceae causing clinical infections in Africa: a systematic review and meta-analysis (2012–20... by Getahun Kahsay Abay, Mebrahtu Teweldemedhin Shfare, Teklay Gebrecherkos Teklu, Kibriti Mehari Kidane, Tsega Kahsay Gebremeskel, Atsebaha Gebrekidan Kahsay, Kebede Embaye Gezae, Saravanan Muthupandian, Tsehaye Asmelash Degene

“…This illustrates the necessity of actively monitoring antimicrobial resistance in Africa to develop interventions aimed at halting the spread of ESBL-PE.…”
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Current methods for detecting and assessing HIV-1 antibody resistance by Stanley Odidika, Stanley Odidika, Stanley Odidika, Martin Pirkl, Martin Pirkl, Thomas Lengauer, Thomas Lengauer, Thomas Lengauer, Philipp Schommers, Philipp Schommers, Philipp Schommers

“…Broadly neutralizing antibodies (bNAbs), which are highly active against HIV-1, represent a promising new approach and clinical trials have demonstrated the potential of bNAbs in the treatment and prevention of HIV-1 infection. …”
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Experimental Validation of Antiobesogenic and Osteoprotective Efficacy of Ginsenoside CK via Targeting Lipid and Atherosclerosis Pathways by Md. Niaj Morshed, Reshmi Akter, Imran Mahmud, Ah-Yeong Gwon, Jin Woo Jeang, Yeong-Geun Lee, Dae Won Park, Deok Chun Yang, Yeon Ju Kim, Se-Chan Kang

“…Additionally, CK treatment induced osteoblast development in MC3T3-E1 cells as shown by increased mineralization and calcium distribution, collagen content, alkaline phosphatase activity, and decreased inflammatory cytokines <i>TNFα</i>, and <i>IL-6</i> and increased the regulated expressions of osteogenic genes including <i>Runx2</i>, <i>ALP</i>, <i>BGLAP</i>, <i>OCN</i>, and <i>Col1a1</i>. …”
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Molecular-genetic pathways of hepatitis C virus regulation of the expression of cellular factors PREB and PLA2G4C, which play an important role in virus replication by E. L. Mishchenko, A. A. Makarova, E. A. Antropova, A. S. Venzel, T. V. Ivanisenko, P. S. Demenkov, V. A. Ivanisenko

“…Therapeutic approaches based on activity inhibition of viral non-structural proteins NS3, NS5A, and NS5B are undergoing clinical trials. …”
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Image-based robotic (ROSA® knee system) total knee arthroplasty with inverse kinematic alignment compared to conventional total knee arthroplasty by Henriëtte M. Eijking, Isobel M. Dorling, Emil H. van Haaren, Roel Hendrickx, Thijs Nijenhuis, Martijn G.M. Schotanus, Lee Bouwman, Jasper Most, Bert Boonen

“…Secondary outcomes include clinical metrics (leg alignment, implant and patient survival), surgical parameters (adverse events, surgery duration, blood loss, hospital stay length, medication use), patient-reported outcomes (symptoms, quality of life, pain), mobility and physical activity measurements, metabolic syndrome, cost-efficacy, and gait and continuous glucose monitoring. …”
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