Single-staged Surgical Correction of Kyphotic Deformity due to Dorsal Spinal Tuberculosis in Pediatric Patients: Outcome Analysis by Mageswaran Shanmugavelu, Makesh Ram Sriraghavan, Prabhu Aloy, Poornima Kumararaja, Sai Vinay Bharadwaj Namala

“…This typically happens during the active stage of the disease or, in some cases, even after the infection has healed. …”
Get full text

Pengaruh Metode Pembelajaran Problem Based Learning yang Diperkaya dengan ARCS Motivational Model terhadap Kualitas Manajemen Kelas dan Motivasi Belajar Siswa secara Online pada Ma... by Allisa Majid, Admaja Dwi Herlambang, Faizatul Amalia

“…The selection of methods and providing motivation for teaching and learning activities during the emergency transition or online learning needs to be considered by teachers in order to achieve learning objectives. …”
Get full text

Biopsy location and tumor-associated macrophages in predicting malignant glioma recurrence using an in-silico model by Pejman Shojaee, Edwin Weinholtz, Nadine S. Schaadt, Friedrich Feuerhake, Haralampos Hatzikirou

“…Additionally, we simulated results on macrophage density and proliferative activity, either in a specified part of the tumor, namely the tumor core or edge (“localized”), or unspecified (“non-localized”). …”
Get full text

Conections between platelets amino acids profile and known cardiometabolic risk factors in patients with coronary artery disease and atrial fibrillation by I.O. Melnychuk

“…The level of glycine in platelets is correlated with most cardiometabolic risk factors, such as: age (r=-0.305), BMI (r=-0.351), TC (r=-0.304), LDL (r=-0.348), ApoA1 (r=0.373 ), ApoB (r=-0.347), IL-6 (r=-0.315), TMAO (r=-0.654), TMA/TMAO ratio (r=0.688), prothrombin index (r=0.317), activated partial thromboplastin time (r=-0.365) and fibrinogen level (r=-0.396), p<0.05. …”
Get full text

The Effect Hydroquinone Extracted from Sonneratia caseolaris Fruit to Control Vibrio harveyi Artificial Infection on Tiger Shrimp, Penaeus monodon Fab. by . Arifuddin, . Sukenda, D. Dana

“…Hydroquinone showed antibacterial activity with MIC at 3000 ppm. Hydroquinone injected shrimp showed higher survival rate compared with control (100% vs 50%). …”
Get full text

Association of reported sleep disturbances with objectively assessed mild cognitive impairment among adults in the United States by Chan Shen, Hao Wang, Arthur Nguimatsa Djiotsop, R. Constance Wiener, Mona Pathak, Sophie Mitra, Patricia A Findley, Usha Sambamoorthi

“…Logistic regression models estimated unadjusted (Model 1) and adjusted associations accounting for sex, race/ethnicity, age, social determinants of health (Model 2), general health (Model 3), depression (Model 4), and pain and physical activity (Model 5). Results: The study cohort included 8877 participants aged ⩾50 years in 2018 (baseline) who were followed up in 2020. …”
Get full text

Integrated analyses uncover new features of atypical memory B cells and novel targets for intervention by Fuli Fan, Shubei Liu, Bin Wang, Xiaojian Song, Wei Wang

“…AMB was characterized by activated mTORC1 signaling and increased p-P38 level (P < 0.05). …”
Get full text

Transcriptome integration analysis revealed that miR-103-3p regulates goat myoblast proliferation by targeting FGF18 by Kunyu Li, Yize Song, Yekai Fan, Hui Zhang, Mingxing Chu, Yufang Liu

“…Bioinformatics analysis, complemented by dual luciferase activity assays revealed that chi-miR-103-3p specifically targets the 3’UTR of FGF18. …”
Get full text

ERK1/2 Inhibition Alleviates Diabetic Cardiomyopathy by Suppressing Fatty Acid Metabolism by Erin McLean, Caroline De Roo, Annabel Maag, Megan Coble, Jefferson Cano, Ruijie Liu

“…Mechanistically, ERK1/2 activation enhanced the expression of fatty acid metabolism genes PPARα, CPT1A, and FACS in the heart, which was reversed by U0126 treatment. …”
Get full text

Interplay of NF-κB and PPAR-γ transcription factors in patients with juvenile systemic lupus erythematosus by Ozgur Kasapcopur, Sezgin Sahin, Amra Adrovic, Kenan Barut, Sinem Durmus, Remise Gelisgen, Hafize Uzun

“…The aim of this study was to evaluate the potential of nuclear factor-kappa B (NF-κB) and peroxisome proliferator-activated receptor-gamma (PPAR-γ) as biomarkers for jSLE.Methods In this study, serum NF-κB and PPAR-γ levels were determined by immunoassay in 42 patients with jSLE. …”
Get full text

Evaluation of an Interdisciplinary Educational Program to Foster Learning Health Systems: Education Evaluation by Sathana Dushyanthen, Nadia Izzati Zamri, Wendy Chapman, Daniel Capurro, Kayley Lyons

“…Throughout the course, they collaborated in small, simulated learning communities (n=5 to 8), engaging in various activities and problem-solving exercises, contributing their unique perspectives and diverse expertise. …”
Get full text

Comprehensive Analysis and Functional Characteristics of Differential Expression of N6-Methyladenosine Methylation Modification in the Whole Transcriptome of Rheumatoid Arthritis by Lei Wan, Jian Liu, Chuanbing Huang, Ziheng Zhu, Kun Wang, Guanghan Sun, Lei Zhu, Zhongxiang Hu

“…Differentially expressed m6A genes were correlated with macrophage activation involved in immune response, vascular endothelium, MAPK signaling pathway, PI3K − Akt signaling pathway, and other inflammatory processes. …”
Get full text

Optimization and calibration of 384-well kinetic Ca2+ mobilization assays for the human transient receptor potential cation channels TRPM8, TRPV1, and TRPA1 by David A. Close, V. Blair Journigan, Paul A. Johnston

“…The improved precision and accuracy of the TRP Ca2+ mobilization assays afforded by FOB ratio data processing enhances their utility for investigating structure activity relationships.…”
Get full text

Att bevisa målbildsuppsåt vid penningtvättsbrott – möjligheter och svårigheter by Jussi Karkkulainen

“…Moreover, the money launderer seldom indicates their willingness to handle only funds derived from criminal activities in an unequivocal way. Based on the analysis, target intent mainly arises in criminal cases where the offender has also been aware of the existence of the relevant circumstance. …”
Get full text

Clinical and Radiological Manifestations of Pulmonary Tuberculosis, Jazan Region, Saudi Arabia by Abuobaida Yassin, Heba M. Shalaby

“…Various risk factors were reported, including smoking, substance abuse, contact with active TB patients, diabetes mellitus, and a history of TB. …”
Get full text

Mechanism of Action of Decitabine in the Treatment of Acute Myeloid Leukemia by Regulating LINC00599 by Fan Du, Ting Jin, Li Wang

“…In comparison to mimic NC, the miR-135a-5p mimic group significantly decreased the relative fluorescence activity ratio of LINC00599 3′-UTR wild-type CCRF-CEM cells. …”
Get full text

Les quais nos 1, 12 et 13 du port romain de Saint-Lupien à Rezé/Ratiatum (Loire-Atlantique) by Xavier Favreau, Nicolas Ménez

“…This common architectural development testifies to a gradual retreat from the shoreline toward the north and suggests a desire, despite this, to maintain port activity and access to the river. This tiering of monumental port terraces, which developed, operated and was modified, only functioned for about a century. …”
Get full text

Age-stratified analysis of the BMI-kidney stone relationship: findings from a national cross-sectional study by Liuliu Zhou, Wei Gu, Yufeng Jiang, Haimin Zhang

“…Weighted logistic regression models were employed to adjust for multiple confounders, including sex, age, race/ethnicity, education level, smoking history, alcohol consumption, coronary heart disease, diabetes mellitus, hypertension, and physical activity. Interaction effects between BMI and key variables such as sex, race/ethnicity and other factors were also analyzed. …”
Get full text

A prospective, multi-site, cohort study to estimate incidence of infection and disease due to Lassa fever virus in West African countries (the Enable Lassa research programme)-Stud... by Suzanne Penfold, Ayola Akim Adegnika, Danny Asogun, Olufemi Ayodeji, Benedict N Azuogu, William A Fischer, Robert F Garry, Donald Samuel Grant, Christian Happi, Magassouba N'Faly, Adebola Olayinka, Robert Samuels, Jefferson Sibley, David A Wohl, Manfred Accrombessi, Ifedayo Adetifa, Giuditta Annibaldis, Anton Camacho, Chioma Dan-Nwafor, Akpénè Ruth Esperencia Deha, Jean DeMarco, Sophie Duraffour, Augustine Goba, Rebecca Grais, Stephan Günther, Énagnon Junior Juvénal Prince Honvou, Chikwe Ihekweazu, Christine Jacobsen, Lansana Kanneh, Mambu Momoh, Aminata Ndiaye, Robert Nsaibirni, Sylvanus Okogbenin, Chinwe Ochu, Ephraim Ogbaini, Énagnon Parsifal Marie Alexandre Logbo, John Demby Sandi, John S Schieffelin, Thomas Verstraeten, Nathalie J Vielle, Anges Yadouleton, Emmanuel Koffi Yovo, Enable Protocol authorship group

“…LF disease cohort participants will be contacted biweekly to identify acute febrile cases, from whom blood samples will be drawn to test for active LASV infection using RT-PCR. Symptom and treatment data will be abstracted from medical records of LF cases. …”
Get full text

Feasibility Aspects of Exploring Exercise-Induced Neuroplasticity in Parkinson’s Disease: A Pilot Randomized Controlled Trial by Hanna Johansson, Malin Freidle, Urban Ekman, Ellika Schalling, Breiffni Leavy, Per Svenningsson, Maria Hagströmer, Erika Franzén

“…The trial design was a parallel-group RCT pilot with a 1 : 1 allocation ratio to either HiBalance or an active control group (HiCommunication). Both groups received one-hour sessions twice weekly, plus home exercises weekly, for 10 weeks. …”
Get full text