Predictive models for the implementation of targeted reproductive management in multiparous cows on automatic milking systems by Fergus P. Hannon, Martin J. Green, Luke O'Grady, Chris Hudson, Anneke Gouw, Laura V. Randall

“…In addition to this, auxiliary data sources, such as rumination and activity monitors, as well as historical cow-level data, are often readily available. …”
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Structured follow-up pathway to support people after transient ischaemic attack and minor stroke (SUPPORT TIA): protocol for a feasibility study and process evaluation by Grace M Turner, Melanie Calvert, Sue Jowett, Robbie Foy, Jonathan Mant, Sarah Tearne, Lou Atkins, Rachael Jones, Smitaa Patel, Phillip Collis

“…Care needs after TIA/minor stroke include information provision (diagnosis and stroke risk), stroke prevention (medication and lifestyle change) and holistic care (residual problems and return to work or usual activities). This protocol describes a feasibility study and process evaluation of an intervention to support people after TIA/minor stroke. …”
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Soil total carbon as a key factor affects soil biota attributes in plant mixtures over time: A meta-analysis by Huiling Zhang, Jinshan Cai, Xu Yang, Jing Huang, Xuan Zhou, Dima Chen

“…However, the potential mechanisms that regulate soil biota (microbes and fauna) attributes (biomass, activity, and abundance) to plant mixtures over experimental time are still unclear. …”
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DigiLoCS: A leap forward in predictive organ-on-chip simulations. by Manoja Rajalakshmi Aravindakshan, Chittaranjan Mandal, Alex Pothen, Stephan Schaller, Christian Maass

“…DigiLoCs enable differentiation between active biological processes (metabolism) and passive processes (permeability and partitioning) by incorporating detailed information on compound-specific characteristics and hardware-specific data. …”
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Study protocol for a Prospective Observational study of Safety Threats and Adverse events in Trauma (PrO-STAT): a pilot study at a level-1 trauma centre in Canada by Melissa McGowan, Charles Keown-Stoneman, Brodie Nolan, Teodor Grantcharov, Eliane M Shore, Anisa Nazir

“…All consecutive trauma team activations over 12 months will be included, with data collected using audio-visual recordings and physiological monitoring. …”
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Genetic Variability, Character Association, Path Coefficient, and Diversity Analysis of Rice (Oryza sativa L.) Genotypes Based on Agro-Morphological Traits by Shubh Pravat Singh Yadav, Sujan Bhandari, Netra Prasad Ghimire, Dipesh Kumar Mehata, Soni Kumari Majhi, Susmita Bhattarai, Samaz Shrestha, Bishnu Yadav, Pratima Chaudhary, Sangita Bhujel

“…Higher genetic advance as a percentage of the mean (GAM) and higher heritability (hb2) for each attribute indicated nonadditive gene activity and highlighted that selection would likely be successful. …”
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The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETA Receptor in Mouse Mesenteric Arteries by Xi Xie, Chen Chen, Cang-Bao Xu, Jie Lin, Lei Cao, Gen Chen, Jie Li

“…However, these effects were significantly inhibited by 3-MA. mmLDL activates autophagy via the Class III PI3K/Beclin-1 pathway and upregulates the ETA receptor via the downstream NF-κB pathway. …”
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Epigenome-wide association study of Chinese monozygotic twins identifies DNA methylation loci associated with estimated glomerular filtration rate by Xueting Qi, Jingjing Wang, Tong Wang, Weijing Wang, Dongfeng Zhang

“…Enrichment analysis revealed several important biological functions and pathways related to eGFR, including alpha-2A adrenergic receptor binding pathway and corticotropin-releasing hormone receptor activity pathway. GeneMANIA results showed that SYNGR3 was co-expressed with MLLT1 and had genetic interactions with AFF4 and EDIL3. …”
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The Effects of Self-Monitoring Using a Smartwatch and Smartphone App on Stress Awareness, Self-Efficacy, and Well-Being–Related Outcomes in Police Officers: Longitudinal Mixed Desi... by Herman Jaap de Vries, Roos Delahaij, Marianne van Zwieten, Helen Verhoef, Wim Kamphuis

“…Initially often seen as “activity trackers,” wearables have gradually expanded to also estimate sleep, stress, and physiological recovery. …”
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Condom use among women of reproductive age (18–49 years) in Puerto Rico during the 2016 Zika virus outbreak: secondary analysis of data from a cross-sectional, population-based, ce... by Carrie K Shapiro-Mendoza, Margaret Christine Snead, Karen T Chang, Ruby A Serrano Rodriguez, Connie Bish, Sascha R Ellington

“…We limited our analytical sample (n=1840) to women at risk for unintended pregnancy, defined as those who were sexually active with a man in the last 3 months and did not report menopause, hysterectomy, current pregnancy or desiring pregnancy.Outcome measures We estimated the weighted prevalence of any condom use among women at risk for unintended pregnancy. …”
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Interaction effect between overweight/obesity and alcohol consumption on hypertension risk in China: a longitudinal study by Xiaoqin Wang, Zhaozhao Hui, Jiaru Sun, Paul D Terry, Xiaohan Ren, Shuangyan Lei, Caihua Wang, Mingxu Wang

“…After adjusting for age, gender, education level, marital status, physical activity, diabetes and smoking, high body mass index (BMI) and light drinking (OR=5.07, 95% CI 3.06 to 8.41), high waist circumference (WC) and light drinking (OR=4.81, 95% CI 2.92 to 7.91), high waist hip ratio and light drinking (OR=2.85, 95% CI 1.84 to 4.42) were the highest risk of all participants in the three combinations. …”
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Chitosan oligosaccharide alleviates DON-induced liver injury via suppressing ferroptosis in mice by Mengjie Liu, Zhenlin Li, Jie Li, Guorong Yan, Chaoqi Liu, Qingqiang Yin, Yeqiang Liu, Xiaoxiang Xu

“…Moreover, COS significantly reduced liver reactive oxygen species (ROS) levels, malondialdehyde (MDA) content, and lactate dehydrogenase (LDH) release in DON-exposed mice, while restoring the activity of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and total antioxidant capacity (T-AOC). …”
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Gastrointestinal absorption and its regulation of hawthorn leaves flavonoids by Junwei Chow, Xiaolei Yang, Jiarong Hu, Qiuxia Yu, Yu Zhong, Xinyi Hu, Jingru Liang, Chenyang Zhu, Shiwei Yan, Longzhou Li, Haiyang Liu, Tiandian Wang, Zihan Wang, Long Gao, Guo Ma

“…In conclusion, flavonoids in HLF were absorbed via passive diffusion accompanied with active transport, intestinal microflora metabolism, bile secretion and intestinal efflux. …”
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Information technologies in the implementation of Language education in a non-linguistic University by Anna L. Morozova, Tat’yana A. Kostyukova, Dzhamilya Kh. Godina

“…The use of information provided on Internet resources can be effective in the implementation of language education, and the material posted on the sites can be selected taking into account the direction of training and adapted to a variety of innovative teaching methods and current needs of students. it is important now to focus on the search for a new didactics the didactics of mixed learning, the development of a new model of shifting emphasis: from focusing on your own content to public types of content; from reproductive methods of learning to active ones; from final assessment to formative; new formats of educational interaction horizontal /joint/mutual learning (peer-to-peer), etc. …”
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Integration of histone modification-based risk signature with drug sensitivity analysis reveals novel therapeutic strategies for lower-grade glioma by Jingyuan Wang, Shuai Yan

“…High-risk tumors showed activation of TGF-β and IL6-JAK-STAT3 signaling pathways, and distinct mutation profiles including TP53 (63% vs 28%), IDH1 (68% vs 85%), and ATRX (46% vs 20%) mutations. …”
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Bioinorganic Synthesis of Polyrhodanine Stabilized Fe3O4/Graphene Oxide in Microbial Supernatant Media for Anticancer and Antibacterial Applications by Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Navid Omidifar, Maryam Zarei, Sonia Bahrani, Khadije Yousefi, Wei-Hung Chiang, Aziz Babapoor

“…Considering the viability percent of cells in the PR/GO/Fe3O4 compound and comparing it with GO/Fe3O4, it can be understood that the toxic effects of polyrhodanine can diminish the metabolic activity of cells at higher concentrations (mostly more than 50 µg/mL), and PR/Fe3O4/Ko exhibited some promotive effects on cell growth, which enhanced the viability percent to more than 100%. …”
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In-Situ Electrospinning Dressings Loaded with Kaempferol for Reducing MMP9 to Promote Diabetic Ulcer Healing by Li J, Meng H, Guo W, Zhou L, Wu S, Gao G, Liu Q, You D, Qu W

“…Jianwen Li,1,2,* Hongqi Meng,3,* Wenlai Guo,3 Lubin Zhou,4 Siyu Wu,3 Guanghui Gao,4 Quanzhe Liu,3 Di You,5 Wenrui Qu2,3 1Gastroenteric Medicine and Digestive Endoscopy Center, the Second Hospital of Jilin University, Changchun, 130041, People’s Republic of China; 2Joint International Research Laboratory of Ageing Active Strategy and Bionic Health in Northeast Asia of Ministry of Education, Changchun, 130041, People’s Republic of China; 3Department of Hand Surgery, the Second Hospital of Jilin University, Changchun, 130041, People’s Republic of China; 4Polymeric and Soft Materials Laboratory, Advanced Institute of Materials Science, School of Chemical Engineering, Changchun University of Technology, Changchun, 130012, People’s Republic of China; 5Department of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, 130012, People’s Republic of China*These authors contributed equally to this workCorrespondence: Di You; Guanghui Gao, Email youdi1118@jlu.edu.cn; ghgao@ccut.edu.cnBackground: Diabetic foot ulcers (DFUs) are often associated with persistent inflammatory response, impaired macrophage polarization, and slow vascular regeneration. …”
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Midgut immune profiling and functional characterization of Aedes aegypti ABC transporter gene(s) using systemic and local bacterial challenges by Vikas Kumar, Shilpi Garg, Diksha Sisodia, Lalita Gupta, Sanjeev Kumar, Vishal Saxena

“…Interestingly, Toll and IMD immune pathways actively participated in the late hours of local bacterial challenges, suggesting that the route of infection influences these immune responses; however, the molecular mechanism behind these phenomena still needs to be explored. …”
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Forecast for the zone of viticulture in European Russia under climate change by L. Yu. Novikova, P. V. Ozerski

“…Davitaya in 1948, and they are still relevant. They are the sum of active temperatures above 10 °C (ΣT10 > 2500 °C), mean of absolute minimum temperatures (Tmin > –35 °C), length of the frost-free period (Lff < 150 days), and hydrothermal coefficient (0.5 < HTC < 2.5). …”
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Expert Consensus on Clinical Application of Lower Limb Rehabilitation Robots by ZHANG Lixin, BAI Dingqun, BAI Yulong, CHEN Wenhua, CHEN Yan, DU Qing, FAN Maohua, HE Hongchen, HUANG Liping, JIA Jie, LI Jianhua, LI Lei, PAN Yu, SU Min, WANG Hongtu, YIN Yong, ZHANG Bi

“…Studies have shown that lower limb rehabilitation robot assisted gait training (medium-level evidence) and joint activity training (low-level evidence) are beneficial for improving lower limb function, gross movement, and gait in children. …”
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