The trunk segmental motion complexity and balance performance in challenging seated perturbation among individuals with spinal cord injury by Mianjia Shan, Chenhao Li, Jiayi Sun, Haixia Xie, Yan Qi, Wenxin Niu, Ming Zhang

“…Methods A total of 17 individuals with SCI and 18 healthy controls participated in challenging sagittal-seated perturbations with hand protection. Upper arm activation was measured using surface electromyography for trial consistency. …”
Get full text

Evaluating Tech Neck: A Pilot Study Using a Self-Developed Questionnaire on Symptoms, Posture, and Preventive Measures by Brigitte Osser, Csongor Toth, Carmen Delia Nistor-Cseppento, Gyongyi Osser, Caius Calin Miuța, Iosif Ilia, Diana Carina Iovanovici, Cristina Aur, Laura Ioana Bondar

“…Increased symptom intensity was associated with reduced ability to perform daily activities (<i>p</i> < 0.001). Conclusions: The study highlights the significant role of ergonomic tools, posture awareness, and regular breaks in mitigating musculoskeletal symptoms. …”
Get full text

A multidisciplinary collaborative care model involving family members in the treatment of type 2 diabetes mellitus and associated diabetes distress in young and middle-aged patient... by Wang Yan-Ping, Peng Lu-Yao, Yuan Xian-Ming, Chen Ting-Ting, Li Lin, Deng Kai-Qin

“…We assessed and compared glycated hemoglobin (HbA1c) levels, Diabetes Distress Scale (DDS) scores, Summary of Diabetes Self-care Activities (SDSCA) scores, and body mass index (BMI) between the two groups be-fore the intervention and three months after. …”
Get full text

Diagnostic Challenges in Uncommon Firearm Injury Cases: A Multidisciplinary Approach by Andrea Vittorio Maria Failla, Gabriele Licciardello, Giuseppe Cocimano, Lucio Di Mauro, Mario Chisari, Francesco Sessa, Monica Salerno, Massimiliano Esposito

“…<b>Methods</b>: A retrospective analysis of autopsy reports from the Institute of Legal Medicine, University of Catania, covering 2019–2023, included 348 judicial inspections and 378 autopsies performed as part of the institute’s overall activities. Among these, seventeen cases of firearm deaths were identified, with three atypical cases selected for detailed analysis. …”
Get full text

Assessment of Impact of Meteorology and Precursor in Long-term Trends of PM and Ozone in a Tropical City by Christian Mark G. Salvador, Angeles D. Alindajao, Karen B. Burdeos, Mark Anthony M. Lavapiez, Jhon Robin Yee, Angel T. Bautista, Preciosa Corazon B. Pabroa, Rey Y. Capangpangan

“…The seven-year measurement also showcased the variability of the atmospheric pollutants during the COVID-19 pandemic of 2020, when O3 substantially increased due to reduced vehicle transport activities. Overall, our results provide insights to better comprehend the sources of the variability of O3 and PM on a long-term temporal scale, as well as implications on relevant environmental policies in controlling air pollutants in a tropical developing region.…”
Get full text

Health risk assessment and microplastic pollution in streams through accumulation and interaction by heavy metals by A.M. Sabilillah, F.R. Palupi, B.K. Adji, A.P. Nugroho

“…The pollution was related to human activities around the streams. The highest accumulation in fish was found in the digestive organs. …”
Get full text

Lifestyle Intervention Improves Heart Rate Recovery from Exercise in Adults with Type 2 Diabetes: Results from the Look AHEAD Study by Paul M. Ribisl, Sarah A. Gaussoin, Wei Lang, Judy Bahnson, Stephanie A. Connelly, Edward S. Horton, John M. Jakicic, Tina Killean, Dalane W. Kitzman, William C. Knowler, Kerry J. Stewart, Look AHEAD Research Group

Get full text

Structure-based identification of HNF4α agonists: Rosmarinic acid as a promising candidate for NAFLD treatment by Xi Chen, Xinqi Zhu, Gang Wu, Xiaobo Wang, Yu Zhang, Nan Jiang

“…Collectively, these findings suggest that rosmarinic acid is a promising HNF4α agonist which is more effective to activate the P1 isoform of HNF4α and holds potential as an effective treatment for NAFLD, providing a foundation for the development of novel lipid-lowering drugs with enhanced efficacy and reduced side effect. …”
Get full text

Computer-Aided Supporting Models of Customized Crack Propagation Sensors for Analysis and Prototyping by Paulina Kurnyta-Mazurek, Rafał Wrąbel, Artur Kurnyta

“…This approach allows for taking advantage of individual software environments, which allows for expanding the scope of analyses and using the developed models and applications in further research activities.…”
Get full text

Dietary addition of compound organic acids improves the growth performance, carcass trait, and body health of broilers by Fang Cai, Meiping Huang, Wei Liu, Xiaoling Wan, Kai Qiu, Xiao Xu

“…Over a 6-week period, various parameters were measured, including serum triglycerides, high-density lipoproteins, lysozyme, immunoglobulins (IgA, IgM), superoxide dismutase (SOD) activity, IL-2, TNF-α, and gene expressions related to lipid metabolism.ResultsOver a 6-week period, the acidifier decreased serum triglycerides and high-density lipoproteins while also enhancing growth performance. …”
Get full text

Neuregulin1 ameliorates metabolic dysfunction-associated fatty liver disease via the ERK/SIRT1 signaling pathways by Chengan Xu, Shouhao Wang, Di Meng, Mingshan Wang, Rong Yan, Yining Dai

“…Conclusion NRG1 might play a protective role in the pathogenesis of MAFLD by activating the downstream ERK1/2 through ErbB2-ErbB3, which promotes the expression of SIRT1 and autophagy markers. …”
Get full text

Exploring Web-Based Support for Suicidal Ideation in the Scottish Population: Usability Study by Heather McClelland, Rory C O'Connor, Laura Gibson, Donald J MacIntyre

“…Lived experience and suicide prevention stakeholders in Scotland have identified a key gap in suicide prevention activities: the lack of 24-hour peer-driven web-based support for people who are suicidal. …”
Get full text

DEmiRNA-mRNA regulatory network reveals miR‐122-5p as a regulatory factor of arginine metabolism in necrotizing enterocolitis by Zhili Ding, Ting Guo, Qiang Tang, Yaqiang Hong, Zhibao Lv, Li Lu, Wenjun Zhuang

“…The DEmiRNA-mRNA regulatory network was constructed and the bioinformatics analysis was performed to identify the target mRNAs and potential roles of the DEmiRNAs. The miR-122-5p activation was explored in vitro in the human intestinal epithelial cell (FHs74Int) and rat intestinal epithelial cell (IEC-6). …”
Get full text

Salinity effect evaluation on the survival rate and hematology of snakeskin gourami juvenile Trichopodus pectoralis by Lies Setijaningsih

“…This study aimed to determine the optimal salinity and its effect on growth performance, survival rate, osmotic activity, and blood description of the snakeskin gourami Trichopodus pectoralis. …”
Get full text

Exploration of the Immune-Related Signatures and Immune Infiltration Analysis in Melanoma by Ai-lan Li, Yong-mei Zhu, Lai-qiang Gao, Shu-yue Wei, Ming-tao Wang, Qiang Ma, You-you Zheng, Jian-hua Li, Qing-feng Wang

“…The Wilcoxon rank-sum test was used to estimate immune infiltration density in the two groups, and results showed that the high-risk group exhibited a lower infiltration density, and the dominant immune cells included M0 macrophages (P=0.023) and activated mast cells (P=0.005).…”
Get full text

Development and validation of a nomogram to predict survival in septic patients with heart failure in the intensive care unit by Tong Tong, Yikun Guo, Qingqing Wang, Xiaoning Sun, Ziyi Sun, Yuhan Yang, Xiaoxiao Zhang, Kuiwu Yao

“…A nomogram model was developed to predict short-term survival probabilities, using 13 variables: age, pneumonia, endotracheal intubation, mechanical ventilation, potassium (K), anion gap (AG), lactate (Lac), activated partial thromboplastin time (APTT), white blood cell count (WBC), red cell distribution width (RDW), hemoglobin-to-red cell distribution width ratio (HRR), Sequential Organ Failure Assessment (SOFA) score, and Charlson Comorbidity Index (CCI). …”
Get full text

Impact of type 2 diabetes mellitus on low-grade inflammation in patients with ST-elevated myocardial infarction by M.V. Bielinskyi, N.M. Seredyuk, A.I. Vytryhovskiy, V.D. Koroliuk

“…These results suggest that the presence of T2DM may exacerbate the pro-inflammatory and pro-thrombotic state that is typically associated with STEMI, thereby emphasizing the critical need for early intervention to prevent or mitigate inflammation and platelet activation in this particular patient population. Type 2 diabetes mellitus patients with ST-segment elevation myocardial infarction show higher levels of inflammation markers and fibronectin, indicating greater low-grade inflammation. …”
Get full text

Incidence of alexithymia in worsening symptoms and quality of life of Systemic Lupus Erythematosus patients (SLE) by Fabio Rapisarda, Concetta Mezzatesta, Antonina Butticè, Alessandro Raffa, Stefano Boca

“…Results: Comparisons between the two groups revealed significant differences in the Systemic Lupus Erythematosus (SLE) patients, compared to the control group, about the difficulty in identifying feelings and distinguishing them from the bodily sensations accompanying emotional activation, the use of conversion as a defence mechanism and the production of positive symptoms.Moreover, in the same group, the difficulty in identifying emotions was correlated with quality of life, since those who have difficulty identifying emotions have a poorer quality of life.Further analysis regarding the construct of alexithymia, within the patient group alone, revealed a tendency towards somatisation and the use of immature defence mechanisms, including conversion, acting out, projection, dissociation and displacement, highlighting a tendency to act out and project emotional suffering.Furthermore, there appeared to be difficulty in sharing emotional distress with others, indicating a deep sense of insecurity and a need for approval, as well as an incidence in the perception of the state of illness leading to a decline in the quality of life. …”
Get full text

Application of deep learning models on single-cell RNA sequencing analysis uncovers novel markers of double negative T cells by Tian Xu, Qin Xu, Ran Lu, David N. Oakland, Song Li, Liwu Li, Christopher M. Reilly, Xin M. Luo

“…We classified DNT cells into two subgroups, naïve DNT (nDNT) cells differentiated by the expression of Ly6C and activated DNT (aDNT) cells differentiated by the expression of MHC-II. …”
Get full text

Experimental study of the piezoelectricity of Middle Pleistocene loess in the Weibei region, China by Yanlin JING, Jie LIU, Qingying LIU, Xiaoxiao DUAN, Na XIE, Dengke YANG

“…Furthermore, research based on the piezoelectricity of loess in loess regions, including soil moisture monitoring, seismic activity monitoring, and predominant period determination, holds great theoretical and practical significance. …”
Get full text