When is “convenient time” for residents?: a trial of Resident Study Log as asynchronous learning tool for residents by Tadayuki Hashimoto, Shoko Ariyoshi, Taira Ariyoshi, Ryosuke Horitani, Mohammad Adrian Hasdianda, Kanapa Kornsawad, Shunsuke Kosugi, Makoto Kikukawa, Tomio Suzuki

“…Participants reported an average satisfaction score of 5.3 out of 6.0 (6-point Likert scale, where 1 indicated ‘not satisfied at all’ and 6 indicated ‘very satisfied’), while the perceived burden averaged 4.0 out of 6.0 (6-point Likert scale, where 1 indicated ‘not burdensome at all’ and 6 indicated ‘very burdensome’). Notably, posting activity peaked at around 23:00, with 17.4% of posts created between midnight and 5:00.Conclusion The Resident Study Log was a simple, low-cost tool, with high satisfaction levels among residents. …”
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Strategies to mitigate the impact of the COVID-19 pandemic on child and youth well-being: a scoping review protocol by Jeanna Parsons Leigh, Henry T Stelfox, Perri R Tutelman, Diane L Lorenzetti, Melanie C Anglin, Kirsten M Fiest, Stephana Julia Moss, Emily A FitzGerald, Stacie Smith, Micaela Harley, Kathryn Birnie, Sara J Mizen

“…Wide-ranging negative effects (eg, social isolation, lack of physical activity) of the COVID-19 pandemic on children and youth are well established. …”
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RIPK2-Mediated Autophagy and Negatively Regulated ROS-NLRP3 Inflammasome Signaling in GMCs Stimulated with High Glucose by Chenlin Gao, Jiao Chen, Fang Fan, Yang Long, Shi Tang, Chunxia Jiang, Jiying Wang, Youhua Xu, Yong Xu

“…Conclusions. Autophagy was activated by high glucose at short time periods but was inhibited in the long term, demonstrating a dual role for high glucose in autophagy of GMCs. …”
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Current Status, Challenges, and Perspectives in the Conservation of Native Honeybees and Beekeeping in Cambodia by Eric Guerin, Chhouk Chheang, Chainarong Sinpoo, Korrawat Attasopa, Nuttapol Noirungsee, Huoqing Zheng, Tial C. Ling, Patcharin Phokasem, Terd Disayathanoowat

“…The four honeybee species native to Cambodia—<i>Apis dorsata</i>, <i>Apis cerana</i>, <i>Apis florea</i>, <i>and Apis andreniformis</i>—play a vital role in ecosystem health and agricultural productivity through their pollination activities. Beekeeping in Cambodia has primarily developed around the introduced species <i>Apis mellifera</i>. …”
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The role of oxidized non-coding RNAs of the epigenome in the development of human diseases (literature review) by S.S. Ostrovska, Ye.N. Dychko, T.Ye. Shumna, G.I. Titov, O.S. Trushenko, P.G. Gerasymchuk, I.Y. Burega

“…The role of these RNAs in carcinogenesis is being actively studied. A large number of them are disrupted at various types of cancer and may play an im­portant role in the onset, metastasis, and therapeutic response of cancer. …”
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Imaging flow cytometry-based cellular screening elucidates pathophysiology in individuals with Variants of Uncertain Significance by Irena Josephina Johanna Muffels, Hans R. Waterham, Giuseppina D’Alessandro, Guido Zagnoli-Vieira, Michael Sacher, Dirk J. Lefeber, Celine Van der Vinne, Chaim M. Roifman, Koen L. I. Gassen, Holger Rehmann, Desiree Y. Van Haaften-Visser, Edward S. S. Nieuwenhuis, Stephen P. Jackson, Sabine A. Fuchs, Femke Wijk, Peter van Hasselt

“…Methods Six assays to evaluate autophagic-, lysosomal-, Golgi- health, mitochondrial function, ER stress, and NF-κβ activity were developed in fibroblasts. Assay sensitivity was verified with compounds (N = 5) and positive control patients (N = 6). …”
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Assessing alcohol industry penetration and government safeguards: the International Alcohol Control Study by Sarah Callinan, Gopalkrishna Gururaj, Shiwei Liu, Sally Casswell, Thomas Karlsson, Jintana Jankhotkaew, Surasak Chaiyasong, Pranil Man Singh Pradhan, Gillian Shorter, Timothy Naimi, Ingeborg Rossow, Keitseope Nthomang, June Yue Yan Leung, Mindaugas Štelemėkas, Mom Kong, Khem Karki, Steve Randerson, Lathika Athauda, Arvind Banavaram, Orfhlaith Campbell, Song Dearak, Emeka W Dumbili, Laura Romero-García, Romtawan Kalapat, Norman Danilo Maldonado Vargas, Juan Felipe Gonzalez-Mejía, Opeyemi Oladunni, Kwame Owino, Juan Camilo Herrera Palacio, Phasith Phatchana, Vanlounny Sibounheuang, Dao The Son, Kate Vallance, Wim van Dalen, Ashley Wettlaufer, Arianne Zamora

“…There were multiple examples of government partnerships or agreements with the alcohol industry as corporate social responsibility activities, and government incentives for the industry in the early COVID-19 pandemic. …”
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Case report: Detecting giant cell arteritis in [68Ga]Ga-DOTA-Siglec-9-PET/CT by Simon M. Petzinna, Jim Küppers, Benedikt Schemmer, Anna L. Kernder, Anna L. Kernder, Claus-Jürgen Bauer, Leon von der Emde, Babak Salam, Jörg H. W. Distler, Anja Winklbauer, Markus Essler, Valentin S. Schäfer

“…ObjectivesThis study aimed to evaluate the diagnostic utility of [68Ga]Ga-DOTA-Siglec-9 positron emission tomography-computed tomography (PET/CT) in assessing disease activity in a patient experiencing a relapse of giant cell arteritis (GCA).Case presentationA 90-year-old male patient with GCA, diagnosed in 2018, was enrolled. …”
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A bibliometric analysis of exosomes in aging from 2007 to 2023 by Zenghui Niu, Meiyu Cui, Yingkun Fu, Lingfeng Zhou, Jiali Wang, Jiali Wang, Yan Lei, Xinrong Fan, Qiang Wang, Jing Yang

“…Both Kapogiannis D and Goetzl E were active authors in this field. Thery C, Valadi H, and Raposo G were the important promoters in this field. …”
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On the thinking of Traditional Chinese Medicine nursing talents cultivation based on the Traditional Chinese Medicine Nursing Inheritance Studio (基于中医护理传承工作站建设浅谈中医护理传承人才培养)... by ZHANG Xuejian (张雪键), TANG Ling (唐玲), ZHANG Dahua (张大华), ZHANG Jing (张敬), LIU Jing (刘静), CUI Yangfang (崔杨芳)

“…Combined with its own characteristics, the Third Affiliated Hospital of Beijing University of Chinese Medicine has carried out a series of TCM inheritance talents around the construction and innovation of Feng Yunhua Traditional Chinese Medicine Nursing Inheritance Studio, actively explored and summarized experience, and achieved good results. …”
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RADAR-AD: assessment of multiple remote monitoring technologies for early detection of Alzheimer’s disease by Manuel Lentzen, Srinivasan Vairavan, Marijn Muurling, Vasilis Alepopoulos, Alankar Atreya, Merce Boada, Casper de Boer, Pauline Conde, Jelena Curcic, Giovanni Frisoni, Samantha Galluzzi, Martha Therese Gjestsen, Mara Gkioka, Margarita Grammatikopoulou, Lucrezia Hausner, Chris Hinds, Ioulietta Lazarou, Alexandre de Mendonça, Spiros Nikolopoulos, Dorota Religa, Gaetano Scebba, Pieter Jelle Visser, Gayle Wittenberg, Vaibhav A. Narayan, Neva Coello, Anna-Katharine Brem, Dag Aarsland, Holger Fröhlich, on behalf of RADAR-AD

“…Results The ANCOVA results indicated significant differences between healthy and AD subjects regarding reduced physical activity, less REM sleep, altered gait patterns, and decreased cognitive functioning. …”
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Network pharmacology and multi-omics validation of the Jianpi-Yishen formula in the treatment of chronic kidney disease by Yuyan Li, Yueming Luo, Yilan Hu, Siting Li, Guandong Li, Wanyangchuan Zhang, Xiufen Gu, Jianting Wang, Shunmin Li, Hong Cheng

“…Additionally, network diagram demonstrated that 11 targets were associated with macrophage activity. In vivo studies indicated that the JPYS formula could reduce blood urea nitrogen and serum creatinine in adenine-induced CKD rats. …”
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Unraveling the link between agricultural patterns and dust storm occurrence in Mesopotamia by Hossein Hashemi, Abdulhakim M Abdi, Amir Naghibi, Pengxiang Zhao, Sara Brogaard, Ali Torabi Haghighi, Ali Mansourian

“…Severe drought events and human activities, particularly water and land management, have led to emerging dust sources in the last few decades. …”
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Aberrant Expression of miR-362 Promotes Lung Cancer Metastasis through Downregulation of Sema3A by Dan Luo, Zheng Zhang, Zhao Zhang, Jia-Yue Li, Jian Cui, Wen-Pu Shi, Xi-Wen Dong, Lin Yuan, Peng Lin, Zhi-Nan Chen, Hui-Jie Bian, Zi-Ling Wang

“…miR-362 is a recently discovered member of the microRNA family, and it modulates a variety of physical activities and plays an important role in the occurrence and development of many tumors. …”
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Resting fMRI-guided TMS evokes subgenual anterior cingulate response in depression by Romain J. Duprat, Kristin A. Linn, Theodore D. Satterthwaite, Yvette I. Sheline, Ximo Liang, Gabriela Bagdon, Matthew W. Flounders, Heather Robinson, Michael Platt, Joseph Kable, Hannah Long, Morgan Scully, Joseph A. Deluisi, Michael Thase, Mario Cristancho, Julie Grier, Camille Blaine, Almaris Figueroa-González, Desmond J. Oathes

“…Results: Stimulations over cortical sites with high rsFC to the sgACC were effective in modulating activity in the sgACC in both healthy controls and depressed patients. …”
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Practice, Experiences, and Facilitators of Simulation-Based Training During One Year of Implementation in 30 Hospitals in Tanzania by Benjamin A. Kamala MD, PhD, Robert Moshiro MD, PhD, Florence S. Kalabamu MD, MMED, Torgeirsen Kjetil BScN, MSc, Godfrey Guga BSc, Beatrice Githiri BSc, Justine Samson BSc, Philimon Chavala BScN, Grace Qorro MD, MPH, Damas Kayera MD, MPH, Ivony Kamala BScN, MPH, Catherine Massay BScN, MSc, Paschal Mdoe MSc, PhD, Vickfarajaeli Daudi MD, MMED, Esto Mduma MSc, PhD, Shally Mwashemele MD, MPH, Felix Bundala MD, MSc, Hege Ersdal MD, PhD, Sara Rivenes Lafontan BScN, MPH, PhD

“…Qualitative data showed a high degree of motivation and participation among all stakeholders, and active use of hospital data, both clinical indicators and training data, was perceived as a success factor. …”
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Development of a Multi-Sensor Mobile Device for Urban Air Quality Monitoring at the Street Corner: The SMILE Project by Jonas Pellegrino, Hassen Aziza, Mathieu Guerin, Pascal Taranto, Wenceslas Rahajandraibe, Blaise Ravelo

“…The project aims to empower end users with the responsibility of carrying, activating, and monitoring their own sensor devices while utilizing specialized apps on their mobile phones.…”
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Adjunctive diagnostic tool for histopathological classification of congenital mesoblastic nephroma based in molecular genetic findings by Hiroshi Hamada, Kenichi Kohashi, Takeshi Iwasaki, Mikiko Hashisako, Yuko Hino, Masahiro Fukuhara, Amane Kamouchi, Naonori Kawakubo, Tatsuro Tajiri, Yoshinao Oda

“…Gene ontology analysis of the highly expressed genes in the EGFR-ITDs tumor group revealed enrichment related to the mitogen-activated protein kinase (MAPK) signaling pathway. p-Mek1/2 and p-Erk1/2 immunoreactivity was significantly increased in the EGFR-ITDs tumor group (p = 0.018 and p = 0.017, respectively). …”
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Staphylococcus aureus induces mitophagy via the HDAC11/IL10 pathway to sustain intracellular survival by Yaji Yang, Haotian Zhou, Feilong Li, Yanhao Zhang, Jianye Yang, Yidong Shen, Ning Hu, Quanming Zou, Leilei Qin, Hao Zeng, Wei Huang

“…Overexpression of HDAC11 and the use of the autophagy activator rapamycin further validated that the HDAC11/IL10 axis regulates mitophagy via the mTOR pathway, which is essential for supporting S. aureus intracellular survival. …”
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Distinct clinical outcomes based on multiple serum cytokine and chemokine profiles rather than autoantibody profiles and ultrasound findings in rheumatoid arthritis: a prospective... by Yukitaka Ueki, Tom W J Huizinga, René E M Toes, Shoichi Fukui, Tomoki Origuchi, Takahiro Maeda, Atsushi Kawakami, Tomohiro Koga, Naoki Matsuoka, Toshihiko Hidaka, Naoki Iwamoto, Mami Tamai, Shin-ya Kawashiri, Akitomo Okada, Ayako Nishino, Tamami Yoshitama, Takahisa Suzuki, Toshimasa Shimizu, Shimpei Morimoto, Tomomi Tsuru, Karin A J van Schie, Masahiro Ayano, Remi Sumiyoshi, Yushiro Endo, Tohru Michitsuji, Kaori Furukawa, Masataka Umeda, Nobutaka Eiraku, Hiroaki Hamada

“…The least absolute shrinkage and selection operator regression of 38 cytokines and chemokines for Clinical Disease Activity Index (CDAI) remission at 12 months resulted in the selection of MIP-1β. …”
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