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48521
Exploring the capacity of microorganism treatment for fermentation and glycosidic aroma bioconversion from rose oil distillation wastewater
Published 2024-12-01“…The process of water-steam distillation is commonly used to extract rose oil, with an extraction efficiency of ~ 0.03–0.05% for active components. However, a significant amount of waste is generated during this process, with a large portion of the distillate being composed of water. …”
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48522
The features of Tat protein of human immunodeficiency virus type 1 (Retroviridae: <i>Lentivirus: Lentivirus humimdef1</i>) non-A6 variants, characteristic for the Russian Federatio...
Published 2024-12-01“…Tat protein is a trans-activator of HIV-1 genome transcription, with additional functions including the ability to induce the chronic inflammatory process. …”
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48523
Investigating the triple-frequency ultrasound-assisted fermented rice lees: Impact on physicochemical, structural, morphological, and metabolic properties
Published 2025-01-01“…The amino acid’s profile of RL was significantly increased as LAB degraded the RL proteins, and the function of TFUT facilitates bacterial activity. Moreover, SEM observation provides convincing evidence that TFUT improves and speeds up the breakdown of proteins’ structures, resulting in irregular and dense structures. …”
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48524
The modern options of chronic hepatitis C antiviral therapy with daclatasvir: results of named patient program
Published 2018-08-01“…No significant elevation of alanine transaminase and aspartate aminotransferase activity, or bilirubin level were detected. Conclusions. …”
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48525
Discovery of the microbiota-gut-brain axis mechanisms of acupuncture for amnestic mild cognitive impairment based on multi-omics analyses: A pilot study
Published 2025-03-01“…Conclusions: Our data imply that acupuncture ameliorates overall cognitive function, along with changes in brain activity, gut microbiota, and serum metabolites, providing preliminary evidence of the mechanisms acting through the MGB axis underlying the effects of acupuncture on aMCI.…”
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48526
Variability and Source Characterization of Regional PM of Two Urban Areas Dominated by Biomass Burning and Anthropogenic Emission
Published 2022-04-01“…For Boracay, the mixed contributions of BB and vehicular activities influenced the formation of PM. Overall, the reanalysis of satellite data captured the long-term variability and origins of surface PM in two vital urban regions in the Philippines. …”
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48527
Effects of Long-Term Serum Starvation on Autophagy, Metabolism, and Differentiation of Porcine Skeletal Muscle Satellite Cells
Published 2024-12-01“…The expression of proteins associated with myogenic and adipogenic differentiation (MHC, MyoD1, peroxisome proliferator-activated receptor <i>γ</i>, and lipoprotein lipase) as well as lipid content were also determined to investigate the effects of long-term serum starvation on SMSC differentiation. …”
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48528
Hei-Gu-Teng Zhuifenghuoluo Granule Modulates IL-12 Signal Pathway to Inhibit the Inflammatory Response in Rheumatoid Arthritis
Published 2018-01-01“…Furthermore, HGT effectively inhibited the activation of IL-12R and STAT4 on IL-12 signaling pathway. …”
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48529
3D nanocomposites of β-TCP-H3BO3-Cu with improved mechanical and biological performances for bone regeneration applications
Published 2025-01-01“…Abstract Recently, 3-D porous architecture of the composites play a key role in cell proliferation, bone regeneration, and anticancer activities. The osteoinductive and osteoconductive properties of β-TCP allow for the complete repair of numerous bone defects. …”
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48530
Data-driven machine learning approaches for simultaneous prediction of peak particle velocity and frequency induced by rock blasting in mining
Published 2025-01-01“…The vibrations generated by rock blasting are a serious and hazardous outcome of these activities, causing harmful effects on the surrounding environment as well as the nearby residents. …”
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48531
Targeting of the HER2/HER3 signaling axis overcomes ligand‐mediated resistance to trastuzumab in HER2‐positive breast cancer
Published 2019-03-01“…SKBR3‐HRG and BT474‐HRG cells lost sensitivity to trastuzumab, which was accompanied by Akt activation. Unexpectedly, trastuzumab in combination with pertuzumab or patritumab also showed limited efficacy toward these cells. …”
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48532
Deficiency of the mitochondrial transporter SLC25A47 minimally impacts hepatic lipid metabolism in fasted and diet-induced obese mice
Published 2025-02-01“…Objective: The peroxisome proliferator-activated receptor-alpha (PPARα) plays a central role in lipid metabolism in the liver by stimulating the expression of hundreds of genes. …”
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48533
Understanding the mechanisms of hypoxia-induced tissue damage in fish: The role of GasderminEa/b in Larimichthys crocea
Published 2025-01-01“…Taken together, these findings demonstrate that hypoxia stress could activate LcGSDMEa/b and induce pyroptosis in the liver of large yellow croakers, thereby contributing to tissue damage. …”
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48534
The Equator Project Research School and Mentoring Network: Evaluated Interventions to Improve Equity in Geoscience Research
Published 2024-12-01“…The work led to the development of recommendations for creating successful interventions for improving participation and retention in research, as well as templates for future, related EDI activities.…”
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48535
Production of subtilisin proteases in bacteria and yeast
Published 2021-03-01“…., thermal stability, general resistance to detergents and specif ic resistance to various oxidants, high activity in various temperature ranges, independence from metal ions, and stability in the absence of calcium. …”
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48536
Advances in Radiation Protection in Oral and Dental Radiology: Pragmatic Approaches and Recent Innovations
Published 2025-01-01“…These innovative materials can prove invaluable for everyday use, offering enhanced protection during extended periods of physical activity. The review findings suggest that samples with nanostructures are more efficient at reducing X-ray energy. …”
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48537
Exploring the impact of genetic factors and fatty acid quality on visceral and overall Fat levels in overweight and obese women: a genetic risk score study
Published 2025-01-01“…We have employed standard methods to measure biochemical factors, anthropometrics, and physical activity levels. Finally, the GRS was created by combining three SNPs [CAV-1 (rs3807992), Cry-1 (rs2287161), and MC4R (rs17782313)]. …”
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48538
Efficacy and safety of edoxaban in patients with chronic thromboembolic pulmonary hypertension: protocol for a multicentre, randomised, warfarin-controlled, parallel group trial -...
Published 2022-07-01“…Warfarin, a vitamin K antagonist, is commonly used for anticoagulation in CTEPH based on historical experience and evidence. The anticoagulant activity of warfarin is affected by food and drug interactions, requiring regular monitoring of prothrombin time. …”
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48539
Portulaca oleracea L. (purslane) extract ameliorates intestinal inflammation in diet-induced obese mice by inhibiting the TLR4/NF-κB signaling pathway
Published 2025-01-01“…(purslane) is a dietary plant and a botanical drug with antioxidant, antidiabetic, and anti-inflammatory activities. However, the effects of purslane against intestinal-inflammation-associated obesity are yet to be studied. …”
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48540
Psychometric properties of the Arabic emotional and behavioral reaction to intrusions questionnaire among sample of Arabic speaking adults
Published 2025-02-01“…Abstract Background Intrusive “thoughts” represent undesirable cognitive activity that can cause distress, and occurs in individuals with and without psychological disorders. …”
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