Evaluation of high-value bioproducts production by marine endophytic fungus Arthrinium sp. FAKSA 10 under solid state fermentation using agro-industrial wastes by Mohammad J. Alsarraf, Fuad Ameen, Abdullah Alfalih, Zirak Sajjad

“…This optimization increased enzyme yields and enhanced antiviral and antioxidant activities. The optimal conditions for solid-state fermentation were a 10 d incubation, 1 mm particle size, 60% initial moisture, 28 °C temperature, and 2 × 107 CFU/mL inoculum size. …”
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Agreement Between Provider-Completed and Patient-Completed Preoperative Frailty Screening Using the Clinical Risk Analysis Index: Cross-Sectional Questionnaire Study by Mehraneh Khalighi, Amy C Thomas, Karl J Brown, Katherine C Ritchey

“…Agreement was the lowest between provider-completed and patient-completed screening questions regarding memory and activities of daily living. ConclusionsRAI-C had moderate agreement when completed by providers versus the participants themselves, with more than a third of patient-completed screens resulting in a higher frailty classification. …”
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Problem-solving ability and future time perspective among the Chinese nursing interns: The mediating role of future work self. by Zhangyi Wang, Yue Zhu, Xiaoping Zhan, Tingrui Wang, Xiaochun Tang, Liping Li, Tao Su, Huifang Zhou, Li Liu, Lamei Chen, Xiaoli Pang, Jiaofeng Peng, Yan Wang, Li Yang

“…It is suggested that nursing managers and educators should actively implement career management and planning programs. …”
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Pengembangan Media Pembelajaran berbasis Website Berdasarkan Gaya Belajar dan Prinsip Universal Design of Learning (UDL) untuk Mata Pelajaran Desain Grafis Percetakan di SMK Negeri... by Yafie Arbian Cipto, Admaja Dwi Herlambang, Faizatul Amalia

“…Therefore, to support teaching and learning activities and to make it easier for students to understand the material presented, a website-based learning media was developed based on the learning styles of students at SMK Negeri 12 Malang in the subject of Printing Graphic Design. …”
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Therapeutic potential of brentuximab vedotin in breast cancer and lymphoma via targeted apoptosis and gene regulation by Abeer Ezzat, Mohga Shafiek, Shimaa Shawki, Shaimaa Abdel-Ghany, Mahmoud Nazih, Hussein Sabit

“…U-937 cells exhibited the most substantial reduction, highlighting Brentuximab’s potent activity against hematologic malignancies. Wound healing assays further revealed that Brentuximab significantly impaired the migration and healing capacity of cancer cells compared to untreated controls. …”
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ITALIANO E DIALETTO: ESPERIENZE DIDATTICHE PER UN CURRICOLO VERTICALE INTEGRATO IN PROSPETTIVA ECOLINGUISTICA by Rosalia La Perna, Antonio Serradifalco

“…At secondary level, the students’ multilingual resources on Italian and the local variety allowed the discovery of the onomastic local repertoire and the creation of glossaries; the contrastive analysis activated metalinguistic processes and improved skills in dealing with different registers. …”
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Prevalence, Treatment, and Unmet Needs of Migraine in the Middle East: A Systematic Review by Taoufik Alsaadi, AbuBakar Al Madani, Mohammed Alhatou, Mona Nada, Abdulrazaq Albilali, Ahmed Al-Qassabi, Hegab Mohamed, Haytham Mohamed, Rowan El Masry, Ghaidaa Ahmed Saifuddin, Suhail Abdullah AlRukn

“…Abstract Introduction Migraine is a debilitating neurological disorder characterized by recurrent throbbing, moderate-to-severe headaches that disrupt daily chores, leisure, and social activities of patients, impacting their overall quality of life (QoL). …”
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S100A8-CAMKK2-AMPK axis confers the protective effects of mild hypothermia against cerebral ischemia-reperfusion injury in rats by Dandan Zhang, Yuting Dai, Xiaoyan Xu, Fuguo Ma, Mingshan Wang, Weiwei Qin

“…Mechanistically, MH down-regulated S100A8 expression, enhancing mitochondrial function via activation of the CAMKK2/AMPK signaling pathway. Moreover, with MH treatment, the administration of CAMKK2 and AMPK inhibitors STO-609 and Dorsomorphin significantly increased oxidative stress, mitochondrial damage, and cell apoptosis, thereby diminishing MH’s neuroprotective effect against cerebral IR injury. …”
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Achieving Medication‐Free Remission in Patients With Juvenile Dermatomyositis by Ilaria Maccora, Hermine I. Brunner, Amy Cassedy, Mekibib Altaye, Megan Quinlan‐Waters, Daniel J. Lovell, Alexei Grom, Sheila T. Angeles‐Han

“…MFR was more common in those who were younger at JDM diagnosis (median 5 vs 8 years, P = 0.008), had early resolution of disease activity (median 11 vs 18 months, P < 0.001), and presented with Gottron papules (χ2 = 5.25; P = 0.022) and elevated lactate dehydrogenase (χ2 = 4.82, P = 0.028). …”
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Dietary Histidine Supplementation Maintained Amino Acid Homeostasis and Reduced Hepatic Lipid Accumulation of Juvenile Largemouth Bass, Micropterus Salmoides by Hualiang Liang, Gangchun Xu, Pao Xu, Jian Zhu, Songlin Li, Mingchun Ren

“…In general, histidine supplementation promoted protein synthesis and lipid decomposition and reduced lipid synthesis by activating the TOR, AAR, PPARα, and PPARγ signaling pathways, which provided a new perspective to solve the fatty liver problem of largemouth bass by nutritional means.…”
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Quantifying uncertainty in anthropogenic causes of injury and mortality for an endangered baleen whale by Daniel W. Linden, Jeffrey A. Hostetler, Richard M. Pace III, Lance P. Garrison, Amy R. Knowlton, Véronique Lesage, Rob Williams, Michael C. Runge

“…Abstract Understanding the causes of mortality for a declining species is essential for developing effective conservation and management strategies, particularly when anthropogenic activities are the primary threat. Using a competing hazards framework allows for robust estimation of the cause‐specific variation in risk that may exist across multiple dimensions, such as time and individual. …”
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Synovial sarcoma. Evaluation of Prognosis with Emphasis on the Study of DNA Ploidy and Proliferation (PCNA and Ki-67) Markers by José M. Lopes, Einar Hannisdal, Bodil Bjerkehagen, Øyvind S. Bruland, Håvard E. Danielsen, Erik O. Pettersend, Manuel Sobrinho-Simões, Jahn M. Nesland

“…We investigated the relationship between (flow and image) DNA cytometry, proliferation activity, clinicopathologic parameters, and relapse-free and overall survival of the patients. …”
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Microscopic Analysis of Temperature Effects on Surface Colonization and Biofilm Morphology of <i>Salmonella enterica</i> by Zachariah Vice, You Zhou, Sapna Chitlapilly Dass, Rong Wang

“…These results demonstrate that the environmental temperature significantly contributes to <i>S. enterica</i> biofilm formation as the higher temperatures encourage bacterial active proliferation and biofilm maturation leading to the development of well-pronounced structures, while the lower temperature may promote cell attachment but, meanwhile, limit the EPS biosynthesis and biofilm maturation. …”
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Factors influencing reselection of village doctors in rural-oriented tuition-waived medical education program in Shanghai, China: a cross-sectional study by Jing Gao, Juhua Zhang, Chenlei Shi, Aiqin Fan, Peng Zhang

“…BackgroundIn order to actively cultivate a new generation of village doctors (NGVDs) who possess a high level of education, provide high-quality healthcare services, Shanghai Municipal Health Bureau, together with the Municipal Education Commission, Municipal Finance Bureau, and Municipal Agriculture Commission initiated Rural-oriented Tuition-waived Medical Education (RTME) in 2006. …”
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MATHEMATICAL RATIONALE FOR CREATING AN APPLICATION FOR CONDUCTING RANDOM MEETINGS «COFFEE BREAK» by Vadym Ziuziun, Daniil Osoka

“…These interactions help raise awareness about the activities in other departments and foster informal and professional connections. …”
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Interpretation of Recent Unrest Events (Bradyseism) at Campi Flegrei, Napoli (Italy): Comparison of Models Based on Cyclical Hydrothermal Events versus Shallow Magmatic Intrusive E... by A. Lima, R. J. Bodnar, B. De Vivo, F. J. Spera, H. E. Belkin

“…CF bradyseism events are driven by cyclical magmatic-hydrothermal activity. Bradyseism events are characterized by cyclical, constant invariant signals repeating over time, such as area deformation along with a spatially well-defined seismogenic volume. …”
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Haemophagocytic lymphohistiocytosis in patients treated with immune checkpoint inhibitors: analysis of WHO global database of individual case safety reports by Alessandro Ceschi, Roberta Noseda, Raffaela Bertoli, Laura Müller

“…Background Immune checkpoint inhibitor (ICI) use in clinical practice has unravelled a spectrum of immune-related adverse events (irAEs) due to immune system hyper-activation. ICI-related haemophagocytic lymphohistiocytosis (HLH) has been recently outlined in single case reports, raising a concern about the need of increasing our knowledge on this rare yet life threatening ICI haematological toxicity.Methods To determine ICI-related HLH clinical, haematological, and coagulation features, its timing and outcome, concurrent irAEs and concomitant infections, we performed a retrospective observational cross-sectional study and queried VigiBase, the WHO global database of suspected adverse drug reactions (ADRs), on September 30th, 2018. …”
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Genome-wide identification of CAMTA gene family in teak (Tectona grandis) and functional characterization of TgCAMTA1 and TgCAMTA3 in cold tolerance by Wenlong Zhou, Jian Du, Runjie Jiao, Xianbang Wang, Tiansong Fang, Guihua Huang

“…Abstract Background Calmodulin-binding transcription activator (CAMTA) proteins play significant roles in signal transduction, growth and development, as well as abiotic stress responses, in plants. …”
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Relationship between motivational climate, anxiety and average mark in pre-service physical education teachers: a cross-sectional study based on structural equation modelling appro... by Eduardo Melguizo-Ibáñez, Gabriel González-Valero, Georgian Badicu, Fatma Hilal Yagin, José Manuel Alonso-Vargas, Luca Paolo Ardigò, Pilar Puertas-Molero

“…Likewise, the branch of study of the sample is related to university degrees in education sciences and physical activity and sport sciences. The Beck Anxiety Inventory (BAI), Perceived Motivational Climate in Sport-2 and an ad hoc socio-demographic questionnaire were used to collect the data. …”
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An eCIRP inhibitor attenuates fibrosis and ferroptosis in ischemia and reperfusion induced chronic kidney disease by Fangming Zhang, Zhijian Hu, Asha Jacob, Max Brenner, Ping Wang

“…Administration of C23 ameliorated renal fibrosis by decreasing the expression of active TGF-β1, α-SMA, collagen deposition, fibronectin and macrophage infiltration to the kidneys. …”
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