Both CYP2C19 and PON1 Q192R Genotypes Influence Platelet Response to Clopidogrel by Thrombelastography in Patients with Acute Coronary Syndrome by Wenxing Peng, Xiujin Shi, Xiaoyu Xu, Yang Lin

“…The objective of this study is to explore the relationships of the effects of CYP2C19 and PON1 Q192R polymorphism on the activity of clopidogrel and the risk of high platelet responsiveness (HPR) by thrombelastography in patients with acute coronary syndrome (ACS). …”
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A <i>SMALL AUXIN UP-REGULATED RNA</i> Gene Isolated from Watermelon (<i>ClSAUR1</i>) Positively Modulates the Chilling Stress Response in Tobacco via Multiple Signaling Pathways by Duo Wang, Gangli Ma, Jia Shen, Xinyang Xu, Weisong Shou, Zhengying Xuan, Yanjun He

“…Furthermore, the overexpressed lines showed reduced reactive oxygen species (ROS) accumulation and increased antioxidant enzyme activity. The qRT-PCR results further indicated that the expression levels of genes associated with abscisic acid (ABA), antioxidant enzymes, and CBF–COR cold-responsive pathways were upregulated in the transgenic tobacco lines. …”
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Comparative analysis of deep learning models for crack detection in buildings by S. Siva Rama Krishnan, M. K. Nalla Karuppan, Adil O. Khadidos, Alaa O. Khadidos, Shitharth Selvarajan, Saarthak Tandon, Balamurugan Balusamy

“…The various parameters such as Batch size, Pooling, Activation functions Learning-rate, Kernel-Size, Normalization, and Optimizers are used for the evaluation of the model. …”
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Decoding oral cancer: insights from miRNA expression profiles and their regulatory targets by Xin Wang, Xin Wang, Shuang Zhang, Shuang Zhang, Shuyi Wang, Tao Cao, Tao Cao, Hong Fan, Hong Fan

“…Functional annotation and pathway enrichment analyses highlighted significant involvement of DEmiRs and their target genes in cell cycle-related processes, including enrichment in the nucleus, transcription factor activity, regulation of nucleosides, nucleotide and nucleic acids, cell growth and/or maintenance, mitotic cell cycle, mitotic M-M/G1 phases an DNA replication. …”
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The latest diagnostic methods for esophageal and gastric examinations. High-resolution manometry is now available in Ukraine by Yu.M. Stepanov, N.V. Prolom, S.O. Tarabarov

“…To date, there are several advanced methods for diagno­sing esophageal and gastric disorders that are actively used in clinical practice, among which high-resolution (HR) manometry stands out. …”
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Prevalence and Associated Factors of Overweight and Obesity among Primary School Children Aged 7–17 Years in Urban Mbarara, Uganda by Benedict Twinomugisha, Abdon Marius Birungi

“….: 3.4–20.0), leisure time activities (O.R.: 0.4, 95% C.I.: 0.2–0.7), frequency of consuming vegetables and fruits (O.R.: 2.8, 95% C.I.: 1.4–5.5), and the type of school attended (O.R.: 0.2, 95% C.I.: 0.1–0.4). …”
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Effectiveness of dynamic neuromuscular stabilization training on strength, endurance, and flexibility in adults with intellectual disabilities, a randomized controlled trial by Hamed Babagoltabar-Samakoush, Behnoosh Aminikhah, Saeid Bahiraei

“…Participants in the intervention group engaged in the DNS training program for 8 weeks, with 3 sessions per week, while the control group maintained their usual activities. The analysis of the outcome measures revealed significant time, group, and time-group interaction effects. …”
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The microbial mechanism of maize residue decomposition under different temperature and moisture regimes in a Solonchak by Fan Huang, Wan Zhang, Lihua Xue, Bahar Razavi, Kazem Zamanian, Xiaoning Zhao

“…Abstract Soil salinization becomes serious under climate change and human activities. Although the residue decomposition contributes lots to soil carbon storage and fertility, the decomposition process and microbial mechanisms on saline-alkali soils are still vague facing climate change. …”
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Managing Friends and Foes: Sanctioning Mutualists in Mixed‐Infection Nodules Trades off With Defense Against Antagonists by Camille E. Wendlandt, Saumik Basu, Angeliqua P. Montoya, Paige Roberts, Justin D. Stewart, Allison B. Coffin, David W. Crowder, E. Toby Kiers, Stephanie S. Porter

“…However, these outcomes may be difficult to achieve simultaneously, since plant defenses activated in response to antagonists can compromise mutualism function, and plant resources allocated to defense may trade off with resources allocated to managing mutualists. …”
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Emotion dysregulation in adolescents is normalized by ADHD pharmacological treatment by Krisztina Kondi, Mária Takács, Evelyn Kovács-Posta, Claudia Szajli, Tünde Sebők-Welker, János M. Réthelyi, Nóra Bunford

“…First- and second-line ADHD pharmacotherapy is effective at ameliorating core symptoms and improving cognitive functioning and accumulating evidence indicates primairly in children and adults, active ADHD pharmacotherapy has beneficial effects on emotional symptoms. …”
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Parent-of-origin effects on nuclear chromatin organization and behavior in a Drosophila model for Williams–Beuren Syndrome by A. V. Medvedeva, E. V. Tokmatcheva, A. N. Kaminskaya, S. A. Vasileva, E. A. Nikitina, A. V. Zhuravlev, G. A. Zakharov, O. G. Zatsepina, E. V. Savvateeva-Popova

“…Our data indicate that the agnts3 locus is capable of trans-regulating gene activity via POEs on the chromatin nuclear organization, thereby affecting behavior.…”
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Effect of galectin-3 and brain natriuretic peptide levels on echocardiographic parameters of left heart chamber following coronary artery bypass grafting by Yulia A. Styazhkina, Irina F. Grishina, Nina B. Poletaeva, Tatyana F. Peretolchina, Olga V. Nikolaenko

“…A comparative analysis of diastolic function in both study groups showed an impaired active relaxation and increased LV myocardial stiffness, which were higher in patients with a prolonged recovery period. …”
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Key bacterial vaginosis-associated bacteria influence each other's growth in biofilms in rich media and media simulating vaginal tract secretions by Lúcia G.V. Sousa, Christina A. Muzny, Nuno Cerca

“…Interestingly, we found that P. bivia growth in NYCIII was influenced by the cell-free supernatant (CFS) of F. vaginae and by the CFS of G. vaginalis in mGTS. This antimicrobial activity appears to happen due to the acidification of the media. …”
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Retrospective trend analysis of biocides in suspended particulate matter of major German rivers by Georg Dierkes, Susanne Schmidt, Christiane Meier, Korinna Ziegler, Jan Koschorreck, Arne Wick

“…Abstract Background Due to their intrinsic biological activity biocides can pose an unintended threat to various aquatic organisms. …”
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Miniaturization and characterization of patient derived hepatocellular carcinoma tumor organoid cultures for cancer drug discovery applications by David A. Close, Paul A. Johnston

“…HCC PDTO's stained with antibodies to signaling pathway proteins and their phosphorylation status allowed comparisons of relative expression levels and inference of pathway activation. Images of HCC PDTO's exposed to ellipticine showed that drugs penetrate Matrigel hydrogels and accumulate in organoid cells. 9-day 384-well HCC organoid cultures exhibited robust and reproducible growth signals suitable for cancer drug testing. …”
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Assessment of Knowledge, Attitude, and Practices toward Knee Pain and Its Various Treatment Modalities among Patients by Akhil Bhalla, Sidharth Verma, Sanjog Ramrao Mekewar, Sasmit Dipak Lotliker, Aanchal Sharma, Oshin Agrawal, Maitri Shah, Hritik Madan, Dhriti Sood

“…Conclusion: The study reveals substantial knee pain prevalence among adults, primarily attributed to osteoarthritis, with a significant impact on daily activities and quality of life. Despite a high reliance on medical practitioners for information, there are abundant misconceptions regarding the condition and significant delays in seeking treatment. …”
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Mapping integral cell-type-specific interferon-induced gene regulatory networks (GRNs) involved in systemic lupus erythematosus using systems and computational analysis by Blessy Kiruba, Akshayata Naidu, Vino Sundararajan, Sajitha Lulu S

“…Furthermore, we found MYB to be a crucial regulator that might activate T cells toward autoimmune responses in SLE. …”
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Sub-seasonal Patterns of PM10 and Black Carbon in a Coastal City: A Case Study of Salé, Morocco by Anas Otmani, Abdeslam Lachhab, Abdelfettah Benchrif, Mounia Tahri, Mohamed Azougagh, Mohammed El Bouch, El Mahjoub Chakir

“…Seasonal variations, wind patterns, and human activities affect air quality. Mitigating traffic emissions and promoting alternative energy sources can improve air quality in Salé. …”
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Removal of heavy metals in industrial wastewater using adsorption technology: Efficiency and influencing factors by Fernando García Ávila, Janneth Cabrera-Sumba, Sandra Valdez-Pilataxi, Jessica Villalta-Chungata, Lorgio Valdiviezo-Gonzales, Cecilia Alegria-Arnedo

“…Among the most efficient adsorbents are acacia cellulose lignin with 99.8% Cr, bentonite clay with 99% Cu, 96% Cd, and 99% Pb, modified sugarcane bagasse with 96.9% Cu, and activated carbon with 82.8% Cr at pH 3. The least efficient adsorbents are natural moss (54.5% Cr) and biochar from corn husks (20% Cr). …”
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Pain Reduction in Patellofemoral Knee Patients During 3-Month Intervention with Biomechanical and Sensorimotor Foot Orthoses: A Randomized Controlled Clinical Study by Steven Simon, Andreas Heine, Jonas Dully, Carlo Dindorf, Oliver Ludwig, Michael Fröhlich, Stephan Becker

“…<b>Background:</b> Patellofemoral pain (PFP) significantly affects patients’ daily activities and consequently reduces their quality of life. …”
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