Association between population viral load surrogate indicator and HIV transmission potential: a prospective cohort study in Xinjiang, China by Qian He, Yongkang Ni, Yuefei Li, Xiaoyuan Hu, Xiaomin Hu, Zhen Ni, Changyu Zeng, Aizimaiti Aikebaier, Bixin Xu, Mingjian Ni

“…Abstract Background New indicators of potential human immunodeficiency virus (HIV) transmission are being actively explored. We aim to categorical testing of the viral load (VL) of persons living with HIV (PLWH) in order to explore new indicators to measure the intensity of the epidemic and the effectiveness of the response in the community. …”
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Complementary cognitive roles for D2-MSNs and D1-MSNs during interval timing by Robert A Bruce, Matthew Weber, Alexandra Bova, Rachael Volkman, Casey Jacobs, Kartik Sivakumar, Hannah Stutt, Youngcho Kim, Rodica Curtu, Kumar Narayanan

“…MSN recordings helped construct and constrain a four-parameter drift-diffusion computational model in which MSN ensemble activity represented the accumulation of temporal evidence. …”
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Development and Optimization of Nano-Hydroxyapatite Encapsulating Tocotrienol-Rich Fraction Formulation Using Response Surface Methodology by Anis Syauqina Mohd Zaffarin, Shiow-Fern Ng, Min Hwei Ng, Haniza Hassan, Ekram Alias

“…Recently, the nano-hydroxyapatite (nHA) has been investigated as a drug delivery vehicle for various drugs and active compounds owing to its excellent biocompatibility, biodegradability, and osteogenic properties. …”
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Genome sequence and metabolic analysis of Pseudomonas fragi unveil the meat spoilage and CO2-antibacterial mechanism under high-oxygen modified atmosphere packaging by Jun Yang, Yikun Xu, Yimin Zhang, Rongrong Liang, Lixian Zhu, Yanwei Mao, Xin Luo, Xiaoyin Yang

“…The TMAP declined above VOCs concentrations significantly (P < 0.05) by inhibiting P. fragi growth and regulating its metabolic activities. The metabolomic analysis further manifested that CO2 inhibited the P. fragi growth by decreasing cell membrane fluidity, disturbing energy metabolism, and inhibiting amino acid metabolism and nucleotide biosynthesis. …”
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The Number of Patients with Acute Myocardial Infarction Decreased and Door-to-Balloon Time Delayed in COVID-19 by Tianyi Ma, Yuli Huang, Wensheng Li, Jianghua Zhong, Hui Yang, Yilei Zhou, Meijun Li, Wenhao Zhong, Yue Cao, Shijuan Lu, Yunzhao Hu

“…At present, COVID-19 is sweeping the world, and all countries are actively responding. During the COVID-19 epidemic, the treatment of patients with acute myocardial infarction (AMI) may be affected. …”
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Mapping ground deformation in the northern Yangtze River estuary using improved MT-InSAR based on ICA and non-stationary analysis by Zhijie Zhang, Songbo Wu, Guoqiang Shi, Xiaoli Ding, Chaoying Zhao, Bochen Zhang, Liang Chen, Zhong Lu

“…The study results identified diverse ground deformation patterns in Nantong, with deformation rates ranging from −56.3 to 45.9 mm/year, attributed to groundwater extraction, urbanization activities, and land reclamation efforts. The study also highlights the significant coastal accretion and land reclamation processes in the study area, demonstrating the potential capability of the MT-InSAR technique in detecting coastal erosion detection and informing land reservation.…”
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Cell Type Specific Suppression of Hyper-Recombination by Human RAD18 Is Linked to Proliferating Cell Nuclear Antigen K164 Ubiquitination by Colette B. Rogers, Wendy Leung, Ryan M. Baxley, Rachel E. Kram, Liangjun Wang, Joseph P. Buytendorp, Khoi Le, David A. Largaespada, Eric A. Hendrickson, Anja-Katrin Bielinsky

“…One of these is gap-filling DNA synthesis at active replication forks and in post-replicative DNA. …”
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Enhanced energy storage performance in Ag(Nb,Ta)O3 films via interface engineering by Xiao Zhai, Jun Ouyang, Weijie Kuai, Yinxiu Xue, Kun Wang, Nengneng Luo, Hongbo Cheng, Hanfei Zhu, Chao Liu, Limei Zheng

“…Environmental-friendly AgNbO3 family have been actively studied for its large polarization and antiferroelectric nature, which greatly boost the electric energy storage performance. …”
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Combined use of zoophytophagous mirids for sustainable biological protection of greenhouse tomato crops by Kouassi A. J. Konan, Coline C. Jaworski, Lucie S. Monticelli, Mnqobi Zuma, Roger Boll, Marie-France N. Kouadio, Thibaud Martin, Benjamin Gard, Roselyne Souriau, Anne-Violette Lavoir, Nicolas Desneux

“…The manipulation of M. pygmaeus densities added to the presence of D. errans could provide a sustainable solution to control multiple pests simultaneously while reducing the damaging phytophagous activity of N. tenuis in tomato crops.…”
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The frequency of mutations in advanced thyroid cancer in Japan: a single-center study by Soji Toda, Hiroyuki Iwasaki, Yoichiro Okubo, Hiroyuki Hayashi, Mei Kadoya, Hiroyuki Takahashi, Tomoyuki Yokose, Yukihiko Hiroshima, Katsuhiko Masudo

“…In conclusion, 58.8% of ATC, 93.8% of PTC, and 42.9% of PDTC had genetic alterations linked to therapeutic agents. Active gene panel testing is required to increase treatment options.…”
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Enhancement of physicochemical and techno-functional properties of soy protein isolate amyloid fibrils by moderate ultrasonic pretreatment by Yunqi Ni, Tianyi Yan, Kai Fu, Congyi Xu, Liang Zhang, Donghong Liu, Wenjun Wang

“…Functionally, SPF with ultrasonic pretreatment had higher emulsifying activity than SPI and SPF0. Rheological analysis further confirmed SPF emulsions’ better mechanical strength over SPI emulsions. …”
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Effect of UV-C Postharvest Disinfection on the Quality of Fresh-Cut 'Tommy Atkins' Mango by Alba Mery Garzón-García, Saúl Ruiz-Cruz, Saúl Dussán-Sarria, José Igor Hleap-Zapata, Enrique Márquez-Ríos, Carmen Lizette Del-Toro-Sánchez, José Agustín Tapia-Hernández, Dalila Fernanda Canizales-Rodríguez, Víctor Manuel Ocaño-Higuera

“…The DPPH• scavenging activity of the UV-C treated mango was also higher (0.60 mM TE/g FW) compared to control (0.27 mM TE/g FW) at the end of storage. …”
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High Glucose Level Disturbs the Resveratrol-Evoked Curtailment of CX3CL1/CX3CR1 Signaling in Human Placental Circulation by Dariusz Szukiewicz, Michal Pyzlak, Grzegorz Szewczyk, Aleksandra Stangret, Seweryn Trojanowski, Michal Bachanek, Wojciech Braksator, Jaroslaw Wejman

“…Anti-inflammatory/antioxidant activities of resveratrol (3,5,4′-trihydroxy-trans-stilbene) are related to the modulation of chemokine CX3CL1 and its receptor, CX3CR1, signaling pathways. …”
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Exploring the paradigm shift towards sustainability: A systematic literature review on circular economy and eco-innovation by Ruchira R N Ghormare, Sana Fatima, Priya Grover, Nidhi Phutela, Vinay Kandpal, Ernesto D. R. Santibanez Gonzalez

“…The results emphasized that the incorporation of eco-innovations can help in mitigating the environmental consequences of production and consumption activities. It also sheds light on notable instances of eco-innovations that have been developed for deployment in the circular economy. …”
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Phytomedicinal armamentarium: A review of inula racemosa-derived alantolactones and isoalantolactones in anticancer therapy by Joshi Gaurav Santoshrao, Smriti Jamwal, Rakesh Kumar, Ekta Bisht, Bisen Harsh Krishnakumar, Shreya Katoch, R.K. Asrani

“…Results: Studies indicate that alantolactone and isoalantolactone exhibit significant anti-cancer activities through various mechanisms. These include the induction of apoptosis, regulation of the cell cycle, inhibition of angiogenesis, and suppression of metastasis. …”
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Machine Learning Based Modeling of Thermospheric Mass Density by Qian Pan, Chao Xiong, Hermann Lühr, Artem Smirnov, Yuyang Huang, Chunyu Xu, Xu Yang, Yunliang Zhou, Yang Hu

“…Further tests have been made by checking the MBiLE model prediction deviations in relation to magnetic local time, day of year, solar flux level, and magnetic activities. No obvious dependences are found for these parameters. …”
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Natural Killer Cells from Malignant Pleural Effusion Are Endowed with a Decidual-Like Proangiogenic Polarization by Annalisa Bosi, Silvia Zanellato, Barbara Bassani, Adriana Albini, Alessandra Musco, Maria Cattoni, Matteo Desio, Elisa Nardecchia, Davide Giuseppe D’Urso, Andrea Imperatori, Lorenzo Dominioni, Douglas M. Noonan, Lorenzo Mortara, Antonino Bruno

“…Natural killer (NK) cells are crucial in tumor recognition and eradication, but their activity is impaired in cancer patients, becoming poorly cytotoxic. …”
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Modulation of the thiol redox proteome by sugarcane ash-derived silica nanoparticles: insights into chronic kidney disease of unknown etiology by Arthur D. Stem, Cole R. Michel, Peter S. Harris, Keegan L. Rogers, Matthew Gibb, Carlos A. Roncal-Jimenez, Richard Reisdorph, Richard J. Johnson, James R. Roede, Kristofer S. Fritz, Jared M. Brown

“…Results Pristine, 200 nm SiNPs induced minimal changes to energy metabolism and proteomic profiles in vitro while treatment with SAD SiNPs resulted in mitochondrial membrane hyperpolarization, inhibited mitochondrial respiration, increased reactive oxygen species generation, and redox proteomic trends suggesting activation of aryl hydrocarbon receptor (AHR) and other signaling pathways with known roles in mitochondrial inhibition and CKD progression. …”
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Does Differential Habitat Selection Facilitate Coexistence Between Badgers and Hedgehogs? by Katie A. Lee, Antonio Uzal, Louise K. Gentle, Philip J. Baker, Richard J. Delahay, Anthony Sévêque, Robert S. Davis, Richard W. Yarnell

“…Badger and hedgehog temporal activity showed no evidence of separation. Although these findings are consistent with hedgehogs avoiding badgers via a landscape of fear, they are also indicative of differential habitat use, highlighting the need for more holistic studies considering variation in habitat selection and food availability when investigating intraguild relationships. …”
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Unveiling the novel role of circadian rhythms in sepsis and septic shock: unexplored implications for chronotherapy by Stewart D. Ramsay, Stewart D. Ramsay, Stewart D. Ramsay, Marni A. Nenke, Marni A. Nenke, Emily J. Meyer, Emily J. Meyer, David J. Torpy, David J. Torpy, Richard L. Young, Richard L. Young, Richard L. Young, Richard L. Young

“…The normal inflammatory response to acute infection displays remarkable circadian rhythmicity in humans with increased inflammatory activity during the normal night or rest period. Severe bloodborne infections, exemplified in sepsis and the progression to septic shock, can not only disrupt the circadian rhythmicity of inflammatory processes but can be exacerbated by circadian misalignment. …”
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