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47321
Development of a neural network for diagnosing the risk of depression according to the experimental data of the stop signal paradigm
Published 2023-01-01“…The stop-signal paradigm (SSP) is an experimental technique to assess a person’s ability to activate deliberate movements or inhibit movements that have become inadequate to external conditions. …”
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47322
Interventional factors influencing natural killer cell immunity in colorectal cancer: a systematic review
Published 2025-02-01“…Additionally, blood transfusion also resulted in decreased NK cell cytotoxicity and activity in CRC patients. Conclusion While surgical stress is one of the significant factor influencing NK cell cytotoxicity, this review indicates that perioperative intervention also contributes to decreased NK cell cytotoxicity. …”
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47323
Characterization of Probiotic Abilities of Lactobacilli Isolated from Iranian Koozeh Traditional Cheese
Published 2017-03-01“…L. plantarum MT.ZH293 exhibited the highest enzymatic activity of β-galactosidase and survival rate in a simulated stomach duodenum passage. …”
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47324
The response of soil microbial community to application of organic amendment to saline land
Published 2025-01-01“…At the same salinity levels, the mean bacterial activity (AUC) and the mean number of substrates were higher than in the soil without organic amendment according to analyses by means of Biolog ECO MicroPlate. …”
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47325
Analysis of serum levels and DNA methylation of fibroblast growth factor 21 using peripheral blood-derived genomes in patients with obesity
Published 2024-09-01“…We recently demonstrated that the FGF21 gene (Fgf21) underwent DNA demethylation in the mouse liver via peroxisome proliferator-activated receptor (PPAR) α during the fetal to lactation periods. …”
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47326
The responsiveness of surgical research to Māori in Aotearoa, New Zealand—a scoping reviewResearch in context
Published 2025-02-01“…Funding: This study was supported by a Health Research Council of New Zealand Health Delivery Research Activation Grant (21/860) and Māori Health Knowledge Translation Grant (25/234). …”
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47327
Exploring Liraglutide’s mechanism in reducing renal fibrosis: the Fsp1-CoQ10-NAD(P)H pathway
Published 2025-01-01“…Second, LIRA inhibited lipid peroxidation by up-regulating T-SOD, GSH-Px, and GSH activities as well as down-regulating the levels of 8-OHDG, MDA, LPO, 4-HNE, 12-Lox, and NOX4 in db/db mice. …”
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47328
Advantages of using T1-mapping in cardiac magnetic resonance imaging in patients with acromegaly
Published 2024-12-01“…The T1-mapping method, which is actively developing, can serve as a marker for early diffuse myocardial fibrosis and help determine the prognosis for patients with acromegalic cardiomyopathy.…”
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47329
NOD-like receptor family pyrin domain containing 3 (rs10754558) gene polymorphism in chronic spontaneous urticaria: A pilot case-control study
Published 2025-01-01“…Methods: Each study group included 62 participants; all were subjected to CSU severity evaluation by the urticaria activity score (UAS), autologous serum skin testing (ASST) and NLRP3 (rs10754558) genotyping. …”
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47330
Unveiling the role of melatonin‐related gene CSNK1D in osteoclastogenesis and its implications for osteoporosis treatment
Published 2025-02-01“…Abstract Osteoporosis (OP) is a prevalent bone disease characterized by reduced bone density and quality, increasing fragility and fracture risk. Osteoclast (OC) activity and circadian rhythm play a role in the pathogenesis of OP. …”
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47331
Effect of non-surgical periodontal therapy on salivary and gingival crevicular fluid concentration of visfatin in periodontal health and disease
Published 2024-07-01“…Conclusion: The results of this investigation suggest a direct correlation between salivary and gingival crevicular fluid visfatin concentration and periodontal tissue inflammation and disease activity.…”
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47332
Noninvasive Evaluation of Liver Function in Morbidly Obese Patients
Published 2019-01-01“…Liver biopsy specimens were obtained intraoperatively and classified according to the NAFLD Activity Score (NAS). NASH clinical score was additionally calculated from laboratory and clinical parameters. …”
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47333
Modeling TEC Maps Over China Using Particle Swarm Optimization Neural Networks and Long‐Term Ground‐Based GPS, COSMIC, and Fengyun Data
Published 2023-04-01“…Furthermore, the new model well captures the diurnal evolution, seasonal variation, and variations in the ionospheric TEC under different solar activity levels. It also well captures the mid‐latitude summer nighttime anomaly over China, and the diurnal anomaly is more pronounced in the solar minimum year (2019) than in the solar maximum year (2015) in terms of the nighttime‐to‐noontime ratio and the range of months it lasts in a year.…”
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47334
Selected health characteristics are associated with urban Canadians’ acceptability of policies promoting healthier restaurant food environments
Published 2025-01-01“…Design: Links between health characteristics and complete agreement levels with selected policies were examined using data in the cross-sectional Targeting Healthy Eating and Physical Activity survey study, that is, a large pan-Canadian study on policy acceptability. …”
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47335
TRPV4 modulates inflammatory responses and apoptosis in enteric glial cells triggered by Clostridioides difficile toxins A and B
Published 2025-01-01“…Our results highlight TRPV4’s role in triggering EGC apoptosis via caspase 3 activation and inhibiting the reduction of Bcl-2, an anti-apoptotic protein in EGCs caused by C. difficile toxins. …”
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47336
Doxycycline-integrated silk fibroin hydrogel: preparation, characterizations, and antimicrobial assessment for biomedical applications
Published 2025-02-01“…Conclusions The findings suggest that SF-DH hydrogel showed sufficient mechanical strength, pore size, antimicrobial activity, and biocompatibility. Further in vivo and clinical tests are required to prove its efficacy in effective socket healing.…”
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47337
Increased TSPO alleviates neuropathic pain by preventing pyroptosis via the AMPK-PGC-1α pathway
Published 2025-01-01“…Our experimental findings showed that TSPO expression was upregulated during neuropathic pain, accompanied by mitochondrial dysfunction, specifically manifested as impaired mitochondrial biogenesis, disrupted mitochondrial dynamics (including insufficient expression of mitochondrial biogenesis and fusion-related proteins, as well as significantly increased expression of fission-related proteins), and activation of pyroptosis. Pharmacological upregulation of TSPO, but not its downregulation, effectively alleviated SNI-induced pain hypersensitivity, improving mitochondrial function and reducing pyroptosis. …”
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47338
JWST, ALMA, and Keck Spectroscopic Constraints on the UV Luminosity Functions at z ∼ 7–14: Clumpiness and Compactness of the Brightest Galaxies in the Early Universe
Published 2025-01-01“…We find that ∼70% of the bright galaxies at z ∼ 7 exhibit clumpy morphologies with multiple subcomponents, suggesting merger-induced starburst activity, which is consistent with SED fitting results showing bursty star formation histories. …”
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47339
RETRACTED ARTICLE: P16INK4a Deletion Ameliorated Renal Tubulointerstitial Injury in a Stress-induced Premature Senescence Model of Bmi-1 Deficiency
Published 2017-08-01“…Our results demonstrated that p16INK4a deletion largely rescued renal aging phenotypes caused by Bmi-1 deficiency, including impaired renal structure and function, decreased proliferation, increased apoptosis, senescence and SASP, DNA damage, NF-κB and TGF-β1/Smad signal activation, inflammatory cell infiltration, and tubulointerstitial fibrosis and tubular atrophy. …”
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47340
Internal Dosimetry in Patients Undergoing Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-[DOTA0-Tyr3] Octerotate: A Single-Center Experience
Published 2025-01-01“…The patients had a mean age of 53.5 ± 12 years (ranging from 36 to 70 years) and imaging data were collected at roughly 0 to 2 hours, 4 to 6 hours, 18 to 24 hours, and 36 to 48 hours after the injection of 6401± 628.4 MBq (range of 5500 MBq-7400 MBq) of 177Lu-[DOTA0-Tyr3] octerotate. Models of time-activity were established for different organs. Finally, using absorbed dose formulation and IDIAC-Dosage software, the mean absorbed dose in the organs was determined. …”
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