[18F]-(2S,4R)4-Fluoroglutamine PET Imaging of Glutamine Metabolism in Murine Models of Hepatocellular Carcinoma (HCC) by Youngho Seo, Miranda C. Craig, Stephanie T. Murphy, Jinjin Feng, Xin Chen, Mariia Yuneva

“…Quantitative in vivo [18F]-(2S,4R)4-fluoroglutamine ([18F]4-FGln or more simply [18F]FGln) metabolic kinetic parameters are compared with activity levels of glutamine metabolism in different types of hepatocellular carcinoma (HCC). …”
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Citizenship in Lithuanian Lexicographical Sources, Youth Worldview, and Media Texts by Marius Smetona

“…The state provides its citizens with rights and duties, and a citizen must be able to use and defend the rights and freedoms granted, as well as actively participate in public life with the ultimate goal of contributing to the well-being of Lithuania. …”
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Magnetoelectric Extracellular Vesicle Latency-Targeting (MELT) Nanotherapeutic for the Block-Lock-and-Kill HIV Eradication Strategy by Mickensone Andre, Nagesh Kolishetti, Adriana Yndart, Arti Vashist, Madhavan Nair, Andrea D. Raymond

“…GFP expression in HC69 at rest is low (GFP^Lo), and upon exposure to LTR, transcription-activating agents (i.e., TNF-α) are induced to be high expressing (GFP^Hi). …”
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Iron induces blood-brain barrier alteration contributing to cognitive impairment in β-thalassaemia mice by Parinda Jamrus, Nuttanan Pholngam, Benjaporn Kiatpakdee, Kittikun Viwatpinyo, Jim Vadolas, Sukonthar Ngampramuan, Saovaros Svasti, Pornthip Chaichompoo

“…While iron-loading had no effect on astrocytes, elevated Iba1 expression in microglia suggests microglia activation as a protective response. However, persistent iron overload may lead to chronic neuroinflammation, neurodegeneration, and cognitive decline. …”
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Spatiotemporal Dynamics of Drought and the Ecohydrological Response in Central Asia by Keting Feng, Yanping Cao, Erji Du, Zengguang Zhou, Yaonan Zhang

“…Due to the influences of climate change and human activities, the resources and environments of the “One Belt and One Road” initiative are facing severe challenges. …”
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USP8‐Dependent Family Tyrosine Kinase Promotes the Malignant Progression of Esophageal Squamous Cell Carcinoma by Upregulating Protein Tyrosine Kinase 2 Expression by Yuechang Wu, Dubiao Xian, Yunzhong Liu, Ding Huang, Qingfeng Liu, Shubo Yang

“…USP8 was shown to stabilize FYN protein expression through its deubiquitinating activity in ESCC cells. Overexpression of FYN reversed the effects of USP8 silencing on the malignant phenotypes of ESCC cells in vitro and in vivo. …”
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Concevoir et mettre en place un Système d’Alerte Précoce Intégré plus efficace dans les zones de montagnes : une étude de cas en Italie du Nord by Carolina García

“…Cependant, les personnes interrogées reconnaissent leur manque de préparation, et sont intéressées pour y remédier en participant activement aux efforts de réduction de risques de catastrophe. …”
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Bibliometric analysis of rhein in the treatment of tumors by Lan Jiang, Lan Jiang, Lan Jiang, Qian Huang, Zhongquan Shi, Yi Yang

“…BackgroundRhein is an anthraquinone compound with a variety of biological activities. It has inhibitory effects on liver cancer, breast cancer, lung cancer, oral cancer, gastric cancer, and other cancers. …”
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The sex differences in diseases progression and prognosis among persons with HIV and HBV coinfection by Rongrong Yang, Qianhui Chen, Fangzhou Jiao, Xingxia Yu, Yong Xiong

“…Among individuals with HIV and HBV coinfection, males had a worse therapeutic effect of HBV-active therapy and poorer prognosis than females.…”
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Validation of a Model Estimating the Budget Impact of Video Capsule Endoscopy for Surveillance of Crohn’s Disease in an Italian Center by Rhodri Saunders, Carlo Calabrese, Dania Gelli, Jason Davis, Rafael Torrejon Torres

“…Mucosal healing, a marker of reduced disease activity, is currently assessed in the colonic sections using ileocolonoscopy and magnetic resonance enteroscopy. …”
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Assessment of Health Risks in Wheat Crop Irrigated by Manka Canal, Dera Ghazi Khan, Pakistan by Muhammad Anwar ul Hassan, Sabiha Javied, Umair Riaz, Muneera A. Saleh, Khalid H. Alamer, Naila Siddique, Ambreen Aslam, Nabeela Noor, Qamar uz Zaman

“…Manka canal’s metal concentration rises from human activities’ garbage. Untreated water from the canal is used by farmers for local crop irrigation. …”
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Assessment of Acid Mining Drainage (AMD) Formation in the Ore Stock and Waste Dam Reservoir Areas: An example of Gümüşhane by Enver Akaryalı, Mehmet Ali Gücer, Selçuk Alemdağ

“…The mining activities, one of the most important uses of natural resources, which causes environmental degradation and different effects depending on the mining operation type and size. …”
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Crucial Genes in Aortic Dissection Identified by Weighted Gene Coexpression Network Analysis by Hongliang Zhang, Tingting Chen, Yunyan Zhang, Jiangbo Lin, Wenjun Zhao, Yangyang Shi, Huichong Lau, Yang Zhang, Minjun Yang, Cheng Xu, Lijiang Tang, Baohui Xu, Jianjun Jiang, Xiaofeng Chen

“…DEGs were rich in certain categories such as MHC class II receptor activity, MHC class II protein complex, and immune response genes. …”
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Unveiling the potential of spirulina algal extract as promising antibacterial and antibiofilm agent against carbapenem-resistant Klebsiella pneumoniae: in vitro and in vivo study by Mohamed I. Selim, Tarek El-banna, Fatma Sonbol, Walaa A. Negm, Engy Elekhnawy

“…Moreover, A. maxima algal extract revealed an antibiofilm activity by crystal violet assay and qRT-PCR. A murine pneumonia model was employed for the in vivo assessment of the antibacterial action of the algal extract. …”
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A Nomogram for Predicting Physical Restraint of Patients in Intensive Care Unit by Yun Wang, Ying Liu, Ya-Li Tian, Su-Lian Gu

“…Age (B = 0.036, odds ratio [OR]: 1.037, 95% confidence interval [CI]: 1.022–1.052, P<0.001), consciousness disorder (B = 0.770, OR: 2.159, 95% CI: 1.216–3.832, P=0.009), coma (B = −1.666, OR: 0.189, 95% CI: 0.101–0.353, P<0.001), passive activity (B = 1.014, OR: 2.756, 95% CI: 1.644–4.618, P<0.001), delirium (B = 0.993, OR: 2.699, 95% CI: 1.097–6.642, P=0.031), −3 < Richmond Agitation Sedation Scale (RASS) score <2 (B = 0.698, OR: 2.009, 95% CI: 1.026–3.935, P=0.042), RASS score ≥2 (B = 1.253, OR: 3.499, 95% CI: 1.126–10.875, P=0.030), and mechanical ventilation (B = 1.696, OR: 5.455, 95% CI: 2.804–10.611, P<0.001) were identified as independent risk factors for PR in the ICU (P<0.05) and included in the nomogram. …”
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Genotypic variability of Pinus sylvestris L. on the drought-resistance attribute by E. Yu. Amineva, A. P. Gureev, T. M. Tabatskaya, O. S. Mashkina, V. N. Popov

“…Based on the results obtained for the selection of Scots pine drought-resistant genotypes we suggest applying a system of criteria characterizing both the ability of the vegetative sphere to survive in drought conditions on the basis of the tissue culture method in vitro (callus tissue formation speed, its viability, frequency of callusogenesis), and the state of the generative sphere with the help of cytogenetic analysis of seed progeny (frequency of mitosis pathologies, the proportion of cells with micronuclei, mitotic activity). The expediency of applying the biotechnological approach was proved by analysis of the gene expression level of stress proteins: the level of AbaH gene expression correlates greatly with the indicator of the viability of callus cultures, including ones on a nutrient medium with an additional stress agent (NaCl). …”
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Peculiarities of the special knowledge application in the investigation of taking a government official or law enforcement officer as hostage by O. Yu. Prokopenko

“…It has been argued that one of the ways to improve the efficiency of detection and investigation of crimes is to use specialised knowledge in the activities of law enforcement agencies. In particular, when investigating the taking of a government official or a law enforcement officer as a hostage, special knowledge should be considered as skills and abilities in a particular area which are used in criminal proceedings and contribute to establishing the truth in the case, which contributes to the effective completion of the investigation. …”
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The effect of triple CFTR modulator therapy and azithromycin on ion channels and inflammation in cystic fibrosis by Suhad Bani Melhim, Lisa E.J. Douglas, James A. Reihill, Damian G. Downey, S. Lorraine Martin

“…As AZ has been reported to require CF transmembrane conductance regulator (CFTR) to be able to reduce interleukin (IL)-8 and given the emergence of highly effective CFTR “triple” modulator therapy (elexacaftor/tezacaftor/ivacaftor; ETI), the aim of this study was to investigate the effect of AZ and ETI, singly and in combination, on ion channel activity and to assess the potential anti-inflammatory effects. …”
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Systematic Evaluation of IMU Sensors for Application in Smart Glove System for Remote Monitoring of Hand Differences by Amy Harrison, Andrea Jester, Surej Mouli, Antonio Fratini, Ali Jabran

“…Hand differences can significantly impair dexterity and independence in daily activities. Accurate assessment of hand function, particularly digit movement, is vital for effective intervention and rehabilitation. …”
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Chemical Changes Under Heat Stress and Identification of Dendrillolactone, a New Diterpene Derivative with a Rare Rearranged Spongiane Skeleton from the Antarctic Marine Sponge <i>... by Andrea Prófumo, Conxita Avila, Adele Cutignano

“…Despite being a species capable of inhabiting volcanically active areas, with frequent water temperature fluctuations due to the existing fumaroles, the results show that diterpenes such as deceptionin, cadlinolide C, membranolide, and tetrahydroaplysulphurin-1 seem to be susceptible to the temperature increase, resulting in a trend to higher concentrations. …”
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