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46141
Tacrolimus- and Mycophenolate-Mediated Toxicity: Clinical Considerations and Options in Management of Post-Transplant Patients
Published 2024-12-01“…For mycophenolate, monitoring inosine monophosphate dehydrogenase activity provides a pharmacodynamic approach to dose optimization, reducing gastrointestinal and hematologic toxicities. …”
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46142
Immunomodulatory Effects of Aerobic Training in Obesity
Published 2011-01-01“…In contrast, BDCA-2 expression at baseline was higher in ONE (ONE 0.25%; LNE 0.11%; LE 0.09%; 𝑃<.05) and decreased in ONE after the 10-week training period (−27%; 𝑃<.05). Gene activations of TLR-4 and TLR-7 with corresponding protein increase were found for all three groups (𝑃<.01/𝑃<.05) compared to pre training. …”
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46143
PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53
Published 2025-02-01“…At the molecular level, PTOV1 destabilized p53 by activating autophagy and recruiting p53 for the cargo receptor SQSTM1 directed autophagic degradation. …”
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46144
Advancements and trends in mangrove species mapping based on remote sensing: A comprehensive review and knowledge visualization
Published 2025-01-01“…China, the United States, and India lead in publishing research on mangrove species mapping, with researchers in the United States being particularly active in international collaborations. Mapping of mangrove species is predominantly concentrated on single time points and across 53 small regions, with the majority of research sites located in India and China. …”
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46145
Prevalence and clinical impact of disseminated intravascular coagulation in acute aortic dissection: a nationwide cohort study
Published 2025-01-01“…With the progression of coagulopathy, characterized by thrombocytopenia, elevated prothrombin time-international normalized ratio, prolonged activated partial thromboplastin time, increased D-dimer, and decreased fibrinogen levels, in-hospital mortality also increased. …”
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46146
Efficacy of Pre-mixed Fungicides Against Rhizoctonia solani and Macrophomina phaseolina Isolated from Soybean
Published 2025-01-01“…Five combo fungicides/ agrochemicals were tested based on their active ingredients at 50 and 100 ppm in four replications. …”
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46147
EIF4A3-induced circ_0022382 promotes breast cancer cell progression through the let-7a-5p/PI3K/AKT/mTOR signaling pathway and SLC7A11 axis
Published 2025-01-01“…In terms of regulatory mechanisms, circ_0022382 activated PI3K/AKT/mTOR signaling pathway and SLC7A11 by sponging let-7a-5p, while knockdown of circ_0022382 contributed to the occurrence of disulfidptosis. …”
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46148
Optimized Extraction of Resveratrol from Arachis repens Handro by Ultrasound and Microwave: A Correlation Study with the Antioxidant Properties and Phenol Contents
Published 2016-01-01“…We compared the efficiency of three different methodologies (conventional maceration [CM], ultrasound-assisted extractions [UAE], and microwave-assisted extractions [MAE]) concerning total phenolics (TP) and resveratrol (t-RSV) content, followed by antioxidant activity (AA) evaluation. By CM, at 1 h, the highest RSV content (1.024±0.036 mg/L) and, correspondingly, the highest DPPH capture (23.90±0.04%) were found. …”
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46149
Human Chorionic Plate-Derived Mesenchymal Stem Cells Restore Hepatic Lipid Metabolism in a Rat Model of Bile Duct Ligation
Published 2017-01-01“…CPT1A expression was changed via microRNA-33—a posttranscriptional regulator of CPT1A—in a peroxisome proliferator-activated receptor α-independent manner. Cellular adenosine triphosphate production—an indicator of mitochondrial function—was reduced after BDL and was restored by CP-MSC transplantation. …”
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46150
Perspectives on Structural, Physiological, Cellular, and Molecular Responses to Desiccation in Resurrection Plants
Published 2018-01-01“…It has also been observed that significant alterations in the process of photosynthesis and photosystem (PS) II activity along with changes in the antioxidant enzyme system also increased the cell wall and membrane fluidity resulting in DT. …”
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46151
An EED/PRC2‐H19 Loop Regulates Cerebellar Development
Published 2025-01-01“…Importantly, an obvious H3K27ac enrichment is found at Ctcf, a trans‐activator of H19, and H3K27me3 enrichment at the H19 imprinting control region (ICR), suggesting that EED regulates H19 in an H3K27me3‐dependent manner. …”
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46152
Low-Frequency Repetitive Transcranial Magnetic Stimulation for Stroke-Induced Upper Limb Motor Deficit: A Meta-Analysis
Published 2017-01-01“…Significant efficacy was found on finger flexibility (SMD = 0.75), hand strength (SMD = 0.49), and activity dexterity (SMD = 0.32), but not on body function (SMD = 0.29). …”
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46153
Impact of interventions on mpox transmission during the 2022 outbreak in Canada: a mathematical modeling study of three different cities
Published 2025-04-01“…Conclusions: Reduction in sexual activity, contact tracing/isolation, and vaccination all contributed to accelerating epidemic control. …”
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46154
The application of blockchain with a comparative approach and its impact on risk, flexibility and internal control evaluation
Published 2024-09-01“…Internal audit is an independent, realistic assurance and advisory activity designed to add value and improve the organization's operations. …”
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46155
Presenting Iran's new economic diplomacy model with an export approach for neighboring countries with an emphasis on cultural and media diplomacy capacities
Published 2024-12-01“…The research community includes businessmen active in neighbor countries, producers, exporters, high-ranking managers, and cultural and media activists. …”
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46156
Design and validation of consumer behavior model based on user-generated content in the banking industry
Published 2024-09-01“…Extended Abstract Introduction Engaging the audience in marketing activities has become one of the most important concerns of marketers, and in this regard, the use of user-generated content has received more attention than in the past (Liu et al, 2019). …”
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46157
The intellectual paradigm and scientific mapping of brand image in International Researches
Published 2025-02-01“…The results showed that the most research was in 2021 with 55 articles (13.8%), and America is the most active country in this field with 80 articles (20%). …”
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46158
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46159
Distinct expression profile reveals glia involvement in the trigeminal system attributing to post-traumatic headache
Published 2024-11-01“…Furthermore, immunohistochemical study revealed a close interaction between activated microglia and reactive astrocytes correlating with increased calretinin interneurons in the Sp5C. …”
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46160
The Recognition and Management of Adverse Effects in Electroconvulsive Therapy: Findings From a Finnish Survey Study
Published 2025-01-01“…This raises concern about whether these AEs are perceived as an insignificant issue in delivering ECT treatment, thus requiring no intervention, or if those AEs should be better recognized and and managed more actively. Conclusions AEs related to ECT treatment are common, but some still appear poorly recognized and treated. …”
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