Refining δ15N isotopic fingerprints of local NOx for accurate source identification of nitrate in PM2.5 by Hao Xiao, Qinkai Li, Shiyuan Ding, Wenjing Dai, Gaoyang Cui, Xiaodong Li

“…Here, we systematically determined and refined δ15N values for six categories of NOx sources in Tianjin using an active sampling method. Moreover, the δ15N values of NO3– in PM2.5 were measured during pre-heating, mid-heating and late-heating periods, which are the most heavily polluted in Tianjin. …”
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Closer adult child–parent relations the stronger the vaccine hesitancy: A cross-sectional study of adult Children’s attitudes toward pneumococcal vaccination of elderly parents and... by Qiqi Wu, Haiyuan Zhu, Runquan Zhang, Cuizhi Li, Qin Xiao, Yuqing Jin, Xiaofeng Liang, Xiongfei Chen, Xiaomei Dong

“…Conversely, those with high income (OR = 0.35) and parents with difficulties in activities of daily living (OR = 0.44) were less likely to exhibit vaccine hesitancy. …”
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Isolation of Helicobacter pylori from Gastric Biopsy of Dyspeptic Patients in Ghana and In Vitro Preliminary Assessment of the Effect of Dissotis rotundifolia Extract on Its Growth by Michael Buenor Adinortey, Charles Ansah, Cynthia Ayefoumi Adinortey, Ansumana Sandy Bockarie, Martin Tangnaa Morna, Damian H. Amewowor

“…It also shows that DRE possess an in vitro anti-H. pylori activity and that DRE has some therapeutic potential against H. pylori infection.…”
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Repurposing of phosphodiesterase-5 inhibitor sildenafil as a therapeutic agent to prevent gastric cancer growth through suppressing c-MYC stability for IL-6 transcription by Zhenzhan Zhang, Wuqing Huang, Donghua Huang, Zhou Xu, Qingfeng Xie, Xin Tan, Wenjun He, Weihao Yang, Guoxin Li, Jianguang Ji, Hao Liu

“…Mechanistically, sildenafil restrained GC growth by directly activating PKG through PDE5 inhibition for regulating c-MYC expression via its phosphorylation and ubiquitination degradation, thereby suppressing c-MYC stability for IL-6 transcription within the downstream IL-6/JAK/STAT3 signalling pathway. …”
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Hemorrhagic syndrome at liver cirrhosis by I. A. Kurkina, O. S. Volkova, M. V. Mayevskaya, V. T. Ivashkin

“…Standard complex tests for hemostasis lose their diagnostic value in this group of patients. Active search of the laboratory methods is conducted, allowing to estimate the risk of bleeding in liver cirrhosis patients. …”
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Hydrocarbon contaminated water remediation using a locally constructed multi-stage bioreactor incorporated with media filtration by S. Antwi-Akomea, B. Fei-Baffoe, E.J.D. Belford, M. Borigu

“…Media filters applied comprised three locally manufactured candle filters two of which were respectively impregnated with granular activated charcoal and sand. The coupling effect of biodegradation and media filtration recorded over 99 % (> 8.7 mg/L) total petroleum hydrocarbon removal. …”
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Chronic cannabis use differentially modulates neural oscillations serving the manipulate versus maintain components of working memory processing by Peihan J. Huang, Jake J. Son, Yasra Arif, Jason A. John, Lucy K. Horne, Mikki Schantell, Seth D. Springer, Maggie P. Rempe, Hannah J. Okelberry, Abraham D. Killanin, Ryan Glesinger, Anna T. Coutant, Thomas W. Ward, Madelyn P. Willett, Hallie J. Johnson, Elizabeth Heinrichs-Graham, Tony W. Wilson

“…In this study, we leveraged magnetoencephalography (MEG) to investigate neurophysiological activity in 45 participants (22 heavy cannabis users) during a numerical WM task, whereby participants were asked to either maintain or manipulate (i.e., rearrange in ascending order) a group of visually presented numbers. …”
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Cardiac Rehabilitation in Women and Men after an Acute Myocardial Infarction by Elizabeth Sellén Sanchén, Vivian Gil García, Nordan Pedroso Almarales, Yunior Rodríguez López, Joaquín Sellén Crombet

“…Symptom-limited maximal stress test was performed to determine risk stratification, functional capacity, activity prescription and provide information to the patient. …”
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An Ultra-Low-Power 2.4 GHz All-Digital Phase-Locked Loop With Injection-Locked Frequency Multiplier and Continuous Frequency Tracking by Muhammad Riaz Ur Rehman, Arash Hejazi, Imran Ali, Muhammad Asif, Seongjin Oh, Pervesh Kumar, Younggun Pu, Sang-Sun Yoo, Keum Cheol Hwang, Youngoo Yang, Yeonjae Jung, Hyungki Huh, Seokkee Kim, Joon-Mo Yoo, Kang-Yoon Lee

“…It consumes only 0.46 mW power with an active area of 0.129 mm².…”
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Development of therapeutic supplement using roasted-cashew-nut to protect cerebral vasoconstriction injury triggered by mixture of petroleum hydrocarbons in the hypothalamus and hi... by J.K. Akintunde, V.O. Akomolafe, R.N. Ugbaja, A.M. Olude, A.D. Folayan

“…Petroleum-related activities have been a health global risk concern, particularly in the limbic disorders. …”
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DHX37 Impacts Prognosis of Hepatocellular Carcinoma and Lung Adenocarcinoma through Immune Infiltration by Yanni Xu, Qiongchao Jiang, Hejun Liu, Xiaoyun Xiao, Dinghong Yang, Phei Er Saw, Baoming Luo

“…These results indicate that DHX37 can serve as a prognostic biomarker in LIHC and LUAD while having an important role in immune tolerance by activating the function of Tregs, MDSC, and T cell exhaustion.…”
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An Evidence-Based Update on the Impact of Local Antimicrobials as Adjunct to Periodontal Therapy by Nabaz Yahya Hussein, Sadat Abdulla Aziz, Twana Mohammed M. Ways, Omed Amiri, Hisham Al-Obaidi, Dianne Ford

“…CHX demonstrated the greatest clinical improvement due to its broad-spectrum antimicrobial activity, strong substantivity, and its application in sustained-release formulations. …”
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Plant Coping with Cold Stress: Molecular and Physiological Adaptive Mechanisms with Future Perspectives by Yan Feng, Zengqiang Li, Xiangjun Kong, Aziz Khan, Najeeb Ullah, Xin Zhang

“…This review summarizes the mechanisms of how plants respond to cold stress, covering four main signal transduction pathways, including the abscisic acid (ABA) signal transduction pathway, Ca²⁺ signal transduction pathway, ROS signal transduction pathway, and mitogen-activated protein kinase (MAPK/MPK) cascade pathway. …”
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Young TPI: empowering animal-free science among the next- generation of scientists by Marta G. Valverde, Marta G. Valverde, Fatima Zohra Abarkan, Fatima Zohra Abarkan, Rebecca Van Eijden, Rebecca Van Eijden, Julia M. L. Menon, Julia M. L. Menon, Nikolas Gaio, Nikolas Gaio, Aarti Ramchandran, Aarti Ramchandran, Victoria C. De Leeuw, Victoria C. De Leeuw

“…This manuscript describes the conception, establishment, and progress of Young TPI from its start to present, detailing its strategy for communication, activities, and funding mechanisms, and ongoing endeavors to enlist new members and forge strategic alliances in pursuit of its mission.…”
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Skin Lesion Classification Through Test Time Augmentation and Explainable Artificial Intelligence by Loris Cino, Cosimo Distante, Alessandro Martella, Pier Luigi Mazzeo

“…To improve the interpretability of the models’ decision-making processes, techniques such as t-distributed Stochastic Neighbor Embedding (t-SNE) and Gradient-weighted Class Activation Mapping (Grad-CAM) are employed. t-SNE is utilized to visualize the high-dimensional latent features of the CNNs in a two-dimensional space, providing insights into how the models group different skin lesion classes. …”
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Melatonin Ameliorates Organellar Calcium Homeostasis, Improving Endoplasmic Reticulum Stress-Mediated Apoptosis in the Vastus Lateralis Muscle of Both Sexes of Obese Diabetic Rats by Diego Salagre, Miguel Navarro-Alarcón, Luis Gerardo González, Mohamed A. Elrayess, Marina Villalón-Mir, Rocío Haro-López, Ahmad Agil

“…Flame atomic absorption spectrometry results showed that melatonin restored VL intraorganellar calcium homeostasis, increasing calcium levels in mitochondria and reducing them in the ER by raising the activity and expression of calcium transporters in both sexes of ZDF rats. …”
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Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women by Veronica Tisato, Paola Secchiero, Gloria Bonaccorsi, Carlo Bergamini, Pantaleo Greco, Giorgio Zauli, Carlo Cervellati

“…The panel of adipokines included interleukin- (IL-) 6, IL-8, IL-1β, adipsin, lipocalin-2/neutrophil gelatinase-associated lipocalin (ngal), TNF-alpha, monocyte chemoattractant protein-1, plasminogen activator inhibitor-1, hepatocyte growth factor, resistin, leptin, adiponectin, and nerve growth factor. …”
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Melanin-like nanoparticles slow cyst growth in ADPKD by dual inhibition of oxidative stress and CREB by Yongzhan Sun, Quan Zou, Huizheng Yu, Xiaoping Yi, Xudan Dou, Yu Yang, Zhiheng Liu, Hong Yang, Junya Jia, Yupeng Chen, Shao-Kai Sun, Lirong Zhang

“…In summary, our findings identify an intracellular target of MMPP and demonstrate its potential for treating ADPKD by simultaneously targeting oxidative stress and CREB transcriptional activity.…”
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JAK2, STAT3 Gene Polymorphisms in Turkish Patients with Behçet’s Disease by Darya Farhoomand Aksoy, Rahime Aksoy, Sevim Gönen, Ümit Ölmez

“…Janus kinase-2 (JAK2) and signal transducer and activator of transcription 3 (STAT3) are intracellular signal transduction molecules that increase the risk of developing some autoimmune diseases. …”
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Effects of Chinese Herbal Medicines on Growth Performance, Antioxidant Capacity, and Liver and Intestinal Health of Hybrid Snakehead (<i>Channa maculata</i> ♀ × <i>Channa. argus</i... by Jiamin Kang, Shuzhan Fei, Junhao Zhang, Haiyang Liu, Qing Luo, Mi Ou, Langjun Cui, Tao Li, Jian Zhao

“…Compared to the control group, the activity of superoxide dismutase (SOD) in plasma and intestine was significantly increased in the FSE and CHMM groups, whereas the content of malondialdehyde (MDA) in plasma and liver was significantly reduced in the SCE group. …”
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