Urban green infrastructure index: Assessing supply of regulating and cultural ecosystem services at a megacity scale by Yury Dvornikov, Valentina Grigorieva, Vyacheslav Vasenev, Mikhail Varentsov, Olga Romzaykina, Olga Maximova, Anastasia Konstantinova, Victor Matasov, Ekaterina Kozlova

“…In this study, we have used open-source geospatial data to quantify regulating (air pollution/noise and stormwater runoff regulation, climate mitigation), and cultural (aesthetic values, recreational activities, observation of flora and fauna) ES at three spatial levels within the Moscow megacity (municipal areas (districts), residential areas (quarters), and regular grid). …”
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Evaluation of the extraction of antioxidant compounds from buriti pulp (Mauritia flexuosa L.) by response surface methodology by Gabriela Mota Nogueira, Flávia Aparecida Reitz Cardoso, Márcia Regina Ferreira Geraldo Perdoncini, Marcos Vieira da Silva, Eliane Sloboda Rigobello

“…The antioxidant capacity of the extracts, evaluated by DPPH, ABTS, and FRAP methods, ranged from 1.23 to 3.47 μmol ET g−1, 6.34–15.86 μmol ET g−1, and 4.74–11.95 μmol ET g−1, respectively, highlighting the broad diversity of antioxidant activities present in the extracts. Data modeling generated statistically significant mathematical models and contour graphs, which allowed the identification of the optimal extraction conditions for the compounds. …”
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A study on the differences in the gut microbiota and metabolism between male and female mice in different stress periods by Yajun Qiao, Yajun Qiao, Yajun Qiao, Juan Guo, Qi Xiao, Jianv Wang, Jianv Wang, Xingfang Zhang, Xingfang Zhang, Xinxin Liang, Xinxin Liang, Lixin Wei, Lixin Wei, Hongtao Bi, Tingting Gao, Tingting Gao

“…The results showed that female mice were highly active and prone to anxious behavior before stress, and the levels of f-Rikenellaceae, f-Ruminococcaceae and 16α-hydroxyestrone were significantly different from those in male mice. …”
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Harnessing the Dual photocatalytic and electrochemical capabilities of pure and Ni-Doped MgO nanostructures for diclofenac detection by V. Bhoomika, K.T. Monalisa, Syed Khasim, T.M. Sharanakuamr, C.R. Ravikumar, N. Basavaraju, T.R. Shashi Shekhar, H.C. Ananda Murthy, K.U. Aravind

“…MgO exhibited an enhanced photocatalytic activity of 68.7 % and MgO:NiO exhibited 81.9 %.According to these studies, the 6 mol% NiO doped MgO is a viable choice for the wastewater treatment and electrochemical detection of diclofenac.…”
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Integrating Analytical Procedures in Routine Practices of Centralized Antiblastic Compounding Units for Valorization of Residual Compounded Drugs by Rita Patrizia Aquino, Giovanni Falcone, Paola Russo, Fabrizio Dal Piaz, Giulia Auriemma, Ferdinando Maria de Francesco, Stefania Cascone, Eduardo Nava, Pasquale Del Gaudio

“…Specifically, the present research focused on fast stability analysis of Active Pharmaceutical Ingredients (APIs) in antiblastic residual compounded drugs with the purpose of demonstrating their potentialities as a resource for possible second-time use. …”
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Anti-Cyclic Citrullinated Peptide Antibodies and Severity of Interstitial Lung Disease in Women with Rheumatoid Arthritis by Alberto Daniel Rocha-Muñoz, Manuel Ponce-Guarneros, Jorge Ivan Gamez-Nava, Eva Maria Olivas-Flores, Mayra Mejía, Pablo Juárez-Contreras, Erika Aurora Martínez-García, Esther Guadalupe Corona-Sánchez, Tania Marlen Rodríguez-Hernández, Mónica Vázquez-del Mercado, Mario Salazar-Páramo, Arnulfo Hernan Nava-Zavala, Ernesto German Cardona-Muñoz, Alfredo Celis, Laura González-Lopez

“…In the logistic regression analysis after adjustment for age, disease duration (DD), smoke exposure, disease activity, functioning, erythrocyte sedimentation rate, and methotrexate (MTX) treatment duration, the characteristics associated with RA-ILD were higher anti-CCP2 titers (P=0.003) and + RF (P=0.002). …”
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Effectiveness of nurse-led volunteer support and technology-driven pain assessment in improving the outcomes of hospitalised older adults: protocol for a cluster randomised control... by Max K Bulsara, Christopher Etherton-Beer, Rosemary Saunders, Kate Crookes, Mustafa Atee, Caroline Bulsara, Beverley Ewens, Olivia Gallagher, Renee M Graham, Karen Gullick, Sue Haydon, Kim-Huong Nguyen, Bev O'Connell, Karla Seaman, Jeff Hughes, Seng Giap Marcus Ang, Debra Scaini

“…Data will be collected on admission, at discharge and at 30 days post discharge, with additional data collected during hospitalisation comprising records of pain assessment and volunteer support activity. The primary outcome of this study will be the change in frailty between both admission and discharge, and admission and 30 days, and secondary outcomes include length of stay, adverse events, discharge destination, quality of life, depression, cognitive function, functional independence, pain scores, pain management intervention (type and frequency) and unplanned 30-day readmissions. …”
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Redox-mediated reverse water gas shift integrated with ammonia cracking over Ni/La0.75Sr0.25Cr0.5Mn0.5O3−δ by Martin Keller, Shih-Yuan Chen, Atul Sharma

“…The mixture of LSCM and Ni catalyst at a weight ratio of 10:1 increases the NH3 cracking activity fivefold compared to using only LSCM. Because the reduction of LSCM proceeds through a two-step mechanism that requires the prior cracking of NH3, it also substantially increases the redox reactivity of LSCM. …”
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Effects of photobiomodulation therapy in patients with chronic non-specific low back pain: protocol for a randomised placebo-controlled trial by Lucíola da Cunha Menezes Costa, Shaiane Silva Tomazoni, Leonardo Oliveira Pena Costa, Layana de Souza Guimarães, Amanda Costa Araujo, Dafne Port Nascimento, Flávia Cordeiro de Medeiros, Marina Athayde Avanzi

“…Treatment sessions will be provided three times a week for 4 weeks (totaling 12 sessions) with patients receiving either placebo or active PBMT. For ethical reasons, all patients, regardless of treatment allocation, will also receive an information booklet based on ‘The Back Book’. …”
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Combination of potassium oxonate with anti-PD-1 for the treatment of colorectal cancer by Yuanyuan Wang, Chenxi Hu, Tianpeng Du, Jiawen Li, Kaiyuan Hui, Xiaodong Jiang

“…The TME were tended to an environment beneficial for killing tumors by enhancing chemotactic factor release, increasing CD8+ T cell infiltration and activation, and decreasing the amount of regulatory T cells. …”
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Geological Conditions and Sedimentary Models of Oligocene and Eocene Effective Source Rocks in the Northern Yinggehai Basin by Jianxiang Pei, Gaowei Hu, Zhipeng Huo, Zhihong Chen, Yabing Chen, Xiaofei Fu, Weihong Wang, Haiyu Liu, Yanan Wang, Jingshuang Luo, Guofei Chen

“…Finally, the sedimentary models for the effective source rocks are established. The tectonic activity controlled the formation of the sedimentary deep depression and the migration of the sedimentary trough center, which migrated from east to west and then south from the Eocene to the Oligocene, leading to the sedimentary migration of good muddy source rocks. …”
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The combined effectiveness of acoustic indices in measuring bird species richness in biodiverse sites in Cyprus, China, and Australia by Christos Mammides, Pan Wuyuan, Guohualing Huang, Rachakonda Sreekar, Christina Ieronymidou, Aiwu Jiang, Eben Goodale, Harris Papadopoulos

“…Human activities are accelerating biodiversity loss, necessitating tools capable of monitoring biodiversity patterns over large spatial and temporal scales. …”
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HnRNPR-mediated UPF3B mRNA splicing drives hepatocellular carcinoma metastasis by Hong Wang, Dong Qian, Jiabei Wang, Yao Liu, Wenguang Luo, Hongyan Zhang, Jingjing Cheng, Heng Li, Yang Wu, Wuhan Li, Jing Wang, Xia Yang, Tianzhi Zhang, Dong Han, Qinyao Wang, Chris Zhiyi Zhang, Lianxin Liu

“…Mechanistically, UPF3B-S protein targets the 3′-UTR of CDH1 mRNA to enhance the degradation of CDH1 mRNA, which results in the downregulation of E-cadherin and the activation of epithelial–mesenchymal transition. Overexpression of UPF3B-S enhances the dephosphorylation of LATS1 and the nuclear accumulation of YAP1 to trigger the Hippo signaling pathway. …”
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SF1-specific deletion of the energy sensor AMPKγ2 induces obesity by Óscar Freire-Agulleiro, Ánxela Estévez-Salguero, Vitor Ferreira, Cassie Lynn Holleman, Julia García-Currás, Ismael González-García, Rubén Nogueiras, Manuel Tena-Sempere, Cristina García-Cáceres, Carlos Diéguez, Miguel López

“…Objective: AMP-activated protein kinase (AMPK) is a heterotrimer complex consisting of a catalytic α subunit (α1, α2) with a serine/threonine kinase domain, and two regulatory subunits, β (β1, β2) and γ (γ1, γ2, γ3), encoded by different genes. …”
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Immune system effectors as biomarkers of prognosis after acute burns in a case-control study by Alejandro Ferrari, Lorena Di Croce, Sabrina Saavedra, Marisel Hartwig, Omar Perrone, María Alejandra Guzmán

“…Laboratory determinations were immunoglobulin G (IgG), immunoglobulin M (IgM), C-reactive protein (CRP), complement C4 protein (C4), total serum protein (TP), albumin, prealbumin, cholesterol (CHOL), pseudocholinesterase activity (CHE), and transferrin. Patients in the deceased group (DG) showed lower initial IgG levels (p < 0.05) than patients in the survivor group (SG), with a negative predictive value (NPV) of 0.86, and this difference persisted during the hospitalization period. …”
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Increased Expression of the Pro-Protein Convertase Furin Predicts Decreased Survival in Ovarian Cancer by Robert E. Page, Andrés J. P. Klein-Szanto, Samuel Litwin, Emmanuelle Nicolas, Raid Al-Jumaily, Peter Alexander, Andrew K. Godwin, Eric A. Ross, Russell J. Schilder, Daniel E. Bassi

“…Background: Proprotein convertases (PCs) are serine proteases that after restricted proteolysis activate many proteins that play a crucial role in cancer such as metalloproteinases, growth factors and growth factor receptors, adhesion molecules, and angiogenic factors. …”
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Systemic Therapy of Neuroendocrine Neoplasia: Single Center Experience from a Cohort of 110 Consecutive Cases by Karin Mayer, Selina Kiry, Anna Yordanova, Hojjat Ahmadzadehfar, Florian C. Gaertner, Ralph A. Bundschuh, Markus Essler, Maria A. Gonzalez-Carmona, Christian P. Strassburg, Hanno Matthaei, Philipp Lingohr, Savita Bisht, Peter Brossart, Georg Feldmann

“…Histological grading, Ki67 proliferation index, functional activity, and presence of metastases were identified as prognostic markers. 10-year overall survival rates were 92%, 44%, and 0% for G1, G2, and G3 tumors, and 60%, 39%, 69%, 53%, and 0% for Ki67 <2%, 3–5%, 6–20%, 21–49%, and >50%, respectively. …”
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Effect of Acupuncture on Neuroplasticity of Stroke Patients with Motor Dysfunction: A Meta-Analysis of fMRI Studies by Qiuyi Lv, Guixing Xu, Yuxin Pan, Tongtong Liu, Xiaodong Liu, Linqing Miao, Xing Chen, Lan Jiang, Jie Chen, Yingjia He, Rong Zhang, Yihuai Zou

“…To analyze the pattern of intrinsic brain activity variability that is altered by acupuncture compared with conventional treatment in stroke patients with motor dysfunction, thus providing the mechanism of stroke treatment by acupuncture. …”
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Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis by Virginie Carrière, Muhammad Imran Arshad, Jacques Le Seyec, Benjamin Lefevre, Muhammad Farooq, Aurélien Jan, Christelle Manuel, Laurence Touami-Bernard, Catherine Lucas-Clerc, Valentine Genet, Hugues Gascan, Jean-Philippe Girard, Frédéric Chalmel, Lucie Lamontagne, Claire Piquet-Pellorce, Michel Samson

“…A transcriptomic study of inflammatory and cell-signaling genes revealed the overexpression of IL-6, TNFα, and several chemokines involved in recruitment/activation of neutrophils (CXCL2, CXCL5, CCL2, and CCL6) at 72 h PI in IL-33 KO mice. …”
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Single-nucleus RNA sequencing reveals distinct pathophysiological trophoblast signatures in spontaneous preterm birth subtypes by Cherilyn Uhm, Jianlei Gu, Weina Ju, Stephanie Pizzella, Hande Oktay, Joyce Yao-Chun Peng, Sararose Guariglia, Yong Liu, Hongyu Zhao, Yong Wang, Ramkumar Menon, Nanbert Zhong

“…In pPROM, heightened inflammation, oxidative stress, and vascular dysregulation with key pathways including tumor necrosis factor signaling, matrix metalloproteinase activation, and integrin-mediated cell adhesion, highlighted an invasive EVT profile potentially driven by hypoxic conditions and immune cell recruitment. …”
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