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45821
Omega-3 fatty acids: molecular weapons against chemoresistance in breast cancer
Published 2025-01-01“…Omega-3 (ω-3) polyunsaturated fatty acids (PUFAs), including docosahexaenoic and eicosapentaenoic acids, have drawn attention for their antitumoral properties and their preventive activities against chemotherapy-induced toxicities in breast cancer. …”
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45822
FGF23-related hypophosphatemia in a patient with small cell lung cancer: a case report and literature review
Published 2023-10-01“…Because the octreotide loading test did not present a suppressive effect on ACTH or FGF23 levels, the patient was treated with phosphate supplementation, active vitamin D and metyrapone, which partially improved the serum phosphate and cortisol levels. …”
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45823
Harmonizing the past: EEG-based brain network unveil modality-specific mechanisms of nostalgia
Published 2025-01-01“…Additionally, nostalgia through the auditory channel induced higher activity intensity in the theta and gamma bands and increased brainwave amplitudes in the alpha bands. …”
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45824
Synthetic Hydrogel Dilutes <i>Serratia plymuthica</i> Growth— Promoting Effect on <i>Brassica napus</i> L. Under Drought Conditions
Published 2025-01-01“…The seed viability test, reactive oxygen species accumulation, and SOD activity showed no adverse effects of applying hydrogel to canola seeds. …”
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45825
Structural and functional changes of Post-Stroke Depression: A multimodal magnetic resonance imaging study
Published 2025-01-01“…This study investigated changes in gray matter volume (GMV), white matter microstructure, and spontaneous brain activity in post-stroke depression (PSD) using multiple MRI techniques, including neurite orientation dispersion and density imaging (NODDI). …”
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45826
Nanomolar detection of essential amino acid in dairy products using a novel electrochemical sensor based on zinc cobaltite nanoflowers embedded porous 3D reduced graphene oxide
Published 2024-01-01“…With a low detection limit of 3 nM, high sensitivity of 19.53 μAμM−1cm−2, and a broad linear range of 0.08–5.93; 5.93–87.18 μM, the sensor demonstrated promising electrocatalytic activity towards L-Trp. Further, the reliability of the sensor was proved by analyzing its stability, repeatability, reproducibility, and selectivity towards L-Trp. …”
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45827
An adenosine analog shows high antiviral potency against coronavirus and arenavirus mainly through an unusual base pairing mode
Published 2024-12-01“…Here, we show that HNC-1664, an adenosine analog with modifications both in ribose and base, has broad-spectrum antiviral activity against positive-strand coronaviruses and negative-strand arenaviruses. …”
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45828
Multimodal neurophenomenology of advanced concentration absorption meditation: An intensively sampled case study of Jhana
Published 2025-01-01“…Our study shows that ACAM-J states induce reliable changes in conscious experience and that these experiences are related to neural activity. Using resting-state fMRI functional connectivity, we found that ACAM-J is associated with decreased within-network modularity, increased global functional connectivity (GFC), and desegregation of the default mode and visual networks. …”
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45829
Development of the Whole Day Matters Toolkit for Primary Care: a consensus-building study to mobilize national public health guidelines in practice
Published 2025-01-01“… IntroductionStrategic knowledge mobilization efforts are needed to enhance uptake and use of the Canadian 24-Hour Movement Guidelines (24HMG), which describe optimal amounts of physical activity, sedentary behaviour and sleep each day for overall health. …”
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45830
Small Extracellular Vesicles from Inflamed Adipose Derived Stromal Cells Enhance the NF-κB-Dependent Inflammatory/Catabolic Environment of Osteoarthritis
Published 2022-01-01“…In comparison with sEVs isolated from unstimulated ADSC, the IL-1β primed sEVs were able to propagate NF-κB activation in bystander joint cells. The effects were more prominent on synoviocytes, possibly because of a higher expression of binding molecules such as CD44. …”
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45831
Noggin Combined With Human Dental Pulp Stem Cells to Promote Skeletal Muscle Regeneration
Published 2024-01-01“…Moreover, BMP4 inhibited Pax7 expression and activated p-Smad1/5/9, while Noggin eliminated BMP4-induced p-Smad1/5/9 in DPSCs. …”
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45832
The effect of resveratrol on the cryopreservation of Mongolian horse semen
Published 2025-01-01“…Proteomics analysis identified 10 differential proteins between the control and optimal RSV concentration groups, with 7 upregulated proteins primarily involved in antioxidant activity and maintaining intracellular redox balance. …”
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45833
Effect of Pressure, Post-Pressing Time, and Polymerization Cycle on the Degree of Conversion of Thermoactivated Acrylic Resin
Published 2018-01-01“…Herein, the effect of different post-pressing times and pressure in two cycles of polymerization on the degree of conversion (DC) of thermally activated acrylic resin (TRRA) is analyzed to optimize the polymerization of this material. …”
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45834
Mesenchymal stem cell‐derived exosomes mitigate amyloid β‐induced retinal toxicity: Insights from rat model and cellular studies
Published 2025-01-01“…Proteomic analysis indicated a decrease in the retinal levels of heat‐shock proteins activated by pathogenic Aβ fibrils following AT‐MSC‐Exosome treatment. …”
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45835
Quality of life in idiopathic pulmonary fibrosis in Latin American countries
Published 2025-01-01“…The total SGRQ-I score was 49 ± 23, with a higher score in the activity domain of 70 ± 23. Torvan index average was 17 ± 6. …”
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45836
Fn14 Deficiency Ameliorates Anti-dsDNA IgG-Induced Glomerular Damage in SCID Mice
Published 2018-01-01“…Recently, it was found that activation of the fibroblast growth factor-inducible 14 (Fn14) signaling pathway damages glomerular filtration barrier in MRL/lpr lupus-prone mice. …”
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45837
Peptide platform for 3D-printed Ti implants with synergistic antibacterial and osteogenic functions to enhance osseointegration
Published 2025-02-01“…Transcriptome sequencing further explored the molecular mechanisms underlying the synergistic effects of 3DTi-NFP, revealing activation of the focal adhesion and PI3K-Akt signaling pathways-key contributors to cell adhesion, matrix formation, and new bone formation. …”
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45838
Lactoferrin: a secret weapon in the war against pathogenic bacteria
Published 2024-10-01“…Moreover, cleavage of the Lf molecule could promote the production of lactoferricins (Lfcins) and lactoferrampin (Lfampin) from the N-terminal end, which are known to often have stronger antimicrobial effects than the native molecule, as well as analogous peptides, such as HLopt2, which have also shown enhanced antimicrobial activity. Bovine Lf (bLf) has been approved by the US Food and Drug Administration (FDA), and the European Food Safety Authority for its use as a dietary supplement in food products. …”
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45839
Variabilities in Retinal Hemodynamics Across the Menstrual Cycle in Healthy Women Identified Using Optical Coherence Tomography Angiography
Published 2024-12-01“…In order to be able to highlight pathological aspects of systemic diseases with ocular activity, it is necessary to understand how physiological fluctuations can influence circulation at the retinal level. …”
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45840
Enhanced humidity-sensing performance of (Zr4+/Sb5+)-codoped TiO2 ceramics with giant dielectric properties
Published 2025-01-01“…The point defects of SbTi⋅ and VO⋅⋅ were claimed to be active centers for water absorption. Furthermore, impedance spectroscopy (IS) analysis revealed that changes in the dielectric properties with varying RH levels were also influenced by interfacial polarization at the surface layer and grain boundaries.…”
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