Global hotspots and trends of nutritional supplements for sick populations from 2000 to 2024 by Chaofan Shi, Haitao Liu, Haitao Liu, Haitao Liu, Te Fu, Yuanquan Li, Haichang Zhao, Feiyue Liu

“…Research focuses on dietary supplementation, oxidative stress, in vitro injections, development, antioxidant activity, double-blind trials, lipid supplements, functional foods, the health of diseased populations, and the risks of NS.ConclusionDifferent supplements each possess unique benefits and should be chosen according to the type of disease to ensure they contain the corresponding nutrients. …”
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Mechanical Strain-Mediated Tenogenic Differentiation of Mesenchymal Stromal Cells Is Regulated through Epithelial Sodium Channels by Hui Yin Nam, Malliga Raman Murali, Raja Elina Ahmad, Belinda Pingguan-Murphy, Hanumantha Rao Balaji Raghavendran, Tunku Kamarul

“…It has been suggested that mechanical strain may elicit cell differentiation in adult somatic cells through activation of epithelial sodium channels (ENaC). However, such phenomenon has not been previously demonstrated in mesenchymal stromal cells (MSCs). …”
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A Brand-New Algorithm for Mapping Algal Biomass in Lakes by Zhengyang Yu, Ronghua Ma, Minqi Hu, Kun Xue, Zhigang Cao, Junfeng Xiong

“…It can be summarized in step 1: inversion of surface chlorophyll a (Chla), step 2: inversion of diffuse attenuation coefficient of the photosynthetic active radiation [Kd(PAR)], and step 3: estimation of algal biomass with a pretrained generalized additive model. …”
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Valproic Acid Enhances Venetoclax Efficacy in Targeting Acute Myeloid Leukemia by Renshi Kawakatsu, Kenjiro Tadagaki, Kenta Yamasaki, Yasumichi Kuwahara, Tatsushi Yoshida

“…This combination also led to the cleavage of poly (ADP-ribose) polymerase (PARP), a substrate of caspases, indicating activation of apoptosis. VPA treatment upregulated the expression of Bax and Bak, further supporting apoptosis induction. …”
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Systematic review: characteristics of myocarditis followed by fixed drug eruption and dry eye syndrome in patients who have been vaccinated with monkeypox in children and adults by R. Mohamad Javier, Stephanie Angela Prijanto, Vallexa Septina Yora, Desak Gede Yuliana Eka Pratiwi, Errini Sabilla Lilhawa Ditsi, Bella Adelia, Verika Christabela Tansuri, Hendry Wijaya, Georaldhy Yussufy Caecarma, Intan Trikumala Damayanti, Anisa Ramadhanti, Atika Rahmaputri, Chabib Fachry Albab, Afif Ferdian, Fatih Farabi, Fadila Risang Ayu, Ni Putu Ika Regina Maharani, Andika Prasetyo Arifin, Eko Setyo Herwanto, Saidah Rahmat A, Safira Dita Arviana, Syifa Nur Lathifah, Nanda Rizki Yulinar, Laksmitha Saktiono Safitri, Basyar Adnani, M. Rizki Fazrian Danu, Natasya Naomi, Dayu Dwi Deria, Aulia Syifa, Panca Andana, Adrian Prasetya, Fachira Rachel Agfata, Magistra Cylvia Margaretha, Subandono Bambang Indrasto, Sukirman, Rachmanto, Hayatun Nufus, Pertiwi Febriana Chandrawati, Aan Dwi Prasetyo, Lucky Sutanto, Moch Aleq Sander

“…Risk factors for infection include sexual activity, STD diagnosis, sexual encounters, and workplace exposure to orthopoxviruses. …”
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lncRNA HHIP-AS1 Promotes the Osteogenic Differentiation Potential and Inhibits the Migration Ability of Periodontal Ligament Stem Cells by Qianyi Qin, Haoqing Yang, Chen Zhang, Xiao Han, Jing Guo, Zhipeng Fan, Jie Guo

“…Then, we found that the alkaline phosphatase activity, in vitro mineralization, and expression levels of bone sialoprotein, osteocalcin, and osterix were increased in PDLSCs by HHIP-AS1. …”
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Performance and gut microbiota of catfish (Clarias gariepinus) fed powdered Moringa oleifera leave as additive (Probiotics) by Jerimoth Kesena Ekelemu, Arnold Ebuka Irabor, Ruth Elohor Anderson

“…The antimicrobial activity of powdered Moringa oleifera leaves on the performance of Clarias gariepinus juveniles was investigated. …”
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The Maternal Cytokine and Chemokine Profile of Naturally Conceived Gestations Is Mainly Preserved during In Vitro Fertilization and Egg Donation Pregnancies by Alicia Martínez-Varea, Begoña Pellicer, Vicente Serra, David Hervás-Marín, Alicia Martínez-Romero, José Bellver, Alfredo Perales-Marín, Antonio Pellicer

“…The main outcome measures were, firstly, to follow up plasma levels of interleukin (IL) 1beta, IL2, IL4, IL5, IL6, IL8, IL10, IL17, interferon gamma, tumor necrosis factor-alpha (TNFα), transforming growth factor-beta (TGFβ), regulated upon activation normal T-cell expressed and secreted (RANTES), stromal cell-derived factor 1 alpha (SDF1α), and decidual granulocyte-macrophage colony-stimulating factor (GM-CSF) during the three trimesters of pregnancy during the three trimesters of pregnancy; secondly, to evaluate if the cytokine and chemokine pattern of ED pregnant women differs from that of those with autologous oocytes and, thirdly, to assess if women with preeclampsia show different cytokine and chemokine profile throughout pregnancy versus women with uneventful pregnancies. …”
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Exploring the association between caffeine intake and benign prostatic hyperplasia: results from the NHANES 2005–2008 by Fei Zhang, Fei Zhang, Fei Zhang, Andong Zhang, Andong Zhang, Andong Zhang, Junyue Tao, Junyue Tao, Junyue Tao, Meng Zhang, Meng Zhang, Meng Zhang, Chaozhao Liang, Chaozhao Liang, Chaozhao Liang

“…BackgroundCoffee is a physiologically active food component prevalent throughout the world, but the association between caffeine intake and benign prostatic hyperplasia (BPH) has been limited in extensive epidemiological studies.MethodsWe conducted a cross-sectional study to evaluate the association between caffeine intake and BPH in adults in the United States using data from the National Health and Nutrition Examination Survey (NHANES) 2005–2008. …”
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Synergistic Antimicrobial Effect of Raspberry (Rubus idaeus L., Rosaceae) Preparations and Probiotic Bacteria on Enteric Pathogens by Justyna Bauza-Kaszewska, Ewa Żary-Sikorska, Andrzej Gugolek, Anna Ligocka, Monika Kosmala, Elżbieta Karlińska, Bartosz Fotschki, Jerzy Juśkiewicz

“…The aim of this research was to examine the antimicrobial activity of red raspberry pomace and seed preparations against enterohemorrhagic Escherichia coli (EHEC), Salmonella Typhimurium, Salmonella Enteritidis, Listeria monocytogenes , and probiotic Lactobacillus rhamnosus strain. …”
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Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis by Shumin Zhao, Shumin Zhao, Ranran Chen, Ranran Chen, Yi An, Yali Zhang, Yali Zhang, Cheng Ma, Ying Gao, Ying Gao, Yanchao Lu, Yanchao Lu, Fei Yang, Fei Yang, Xue Bai, Xue Bai, Jingjing Zhang, Jingjing Zhang, Jingjing Zhang

“…The phenotype onset date, life span, locomotor activity, and pathological changes in the spinal cord were determined and recorded subsequently. …”
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Divergent thinking in groups during cold-water immersion is impaired by cold stress not the cold shock response by Max Kailler Smith, Max Kailler Smith, Rebecca Weller, Rebecca Weller, Tony Duong, Tony Duong, Rebecca McClintock, Rebecca McClintock, Matthew Peterson, Nathaniel Barr, Douglas M. Jones, Timothy L. Dunn

“…To date, research shows that executive functioning is generally impaired by intense, acute stress, which implies the ability to think through potential actions to maximize survival would also be impaired by the cold shock response.MethodsTo examine whether the severity of cold shock response impairs higher-level thinking in a group, 29 active duty service members completed a group format Divergent Association Task (DAT; 4–5 per group) prior to and during a 13-min cold-water immersion (water temperature: 1.3°C, air temperature: −2.7°C).ResultsResults showed no relationship between cold shock response magnitude, indexed by peak heart rate, and DAT performance. …”
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Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases by Sandipan Dasgupta, Subhasundar Maji, Sanjay Dey, Moitreyee Chattopadhyay, Ananya Chanda, Satarupa Acharjee, Kousik Santra, Kazi Asraf Ali

“…Silver and curcumin-based nanocomposites provide controlled release of active ingredients over extended periods, protecting bioactive compounds from degradation. …”
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A software module to assess the metabolic potential of mutant strains of the bacterium <i>Corynebacterium glutamicum</i> by F. V. Kazantsev, M. F. Trofimova, T. M. Khlebodarova, Yu. G. Matushkin, S. A. Lashin

“…One of the bacterial species actively used in biotechnological production is Co­rynebacterium glutamicum. …”
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Evaluation of Groundwater for Arsenic Contamination Using Hydrogeochemical Properties and Multivariate Statistical Methods in Saudi Arabia by Abdullah S. Al-Farraj, Mohammad I. Al-Wabel, Mohamed Hamza El-Saeid, Ahmed H. El-Naggar, Zaheer Ahmed

“…Spatial evaluation of the PCA results indicated that this secondary mechanism of arsenic mobilization may be active and correlates positively with total organic carbon. …”
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Exploring the Anticancer Potential of MonoHER (7-Mono-O-(β-Hydroxyethyl)-Rutoside): Mitochondrial-Dependent Apoptosis in HepG2 Cells by Chujie Li, Yue Wang, Jian Liang, Guido R. M. M. Haenen, Yonger Chen, Zhengwen Li, Ming Zhang, Ludwig J. Dubois

“…Conclusion: MonoHER can inhibit cell growth and induce apoptosis especially in HepG2 human liver cancer cells by triggering the mitochondrial signal transduction pathway, leading to the release of cytochrome C in the cytoplasm and the subsequent activation of caspase-9 and caspase-3. Future research should further explore MonoHER’s mechanism of action, efficacy, and potential for clinical translation.…”
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Rapid assessment of the osteogenic capacity of hydroxyapatite/aragonite using a murine tibial periosteal ossification model by Emma Steijvers, Yunshong Shi, Hong Lu, Weixin Zhang, Yitian Zhang, Feihu Zhao, Baichuan Wang, Louise Hughes, Jake E. Barralet, Giulia Degli-Alessandrini, Igor Kraev, Richard Johnston, Zengwu Shao, Frank H. Ebetino, James T. Triffitt, R. Graham G. Russell, Davide Deganello, Xu Cao, Zhidao Xia

“…To understand the biodegradation and the cellular activity at the cell/biomaterial interfaces, non-decalcified specimens were resin embedded and sections subjected to combined scanning electron microscopy (SEM)/electron backscatter diffraction (EBSD)/energy dispersive X-ray spectrometry (EDS) analysis. …”
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Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue by Jiahui Chang, Jiahui Chang, Jiahui Chang, Wanyu Wu, Wanyu Wu, Wanyu Wu, Ping Qian, Zhaoxu Lu, Xuejia He, Fang Wang, Ting Zhang, Ting Zhang, Ting Zhang

“…Enrichment analysis showed that the lactylation of proteins Atp5mg, and Atp5po exhibited ATP hydrolysis activity. Mtatp8 and Atp5po were involved in biological processes such as mitochondrial transmembrane transport, and Mtatp8, Atp5mg, and Atp5po participate in oxidative phosphorylation and thermogenesis pathways. …”
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Screening of Efficient Antifreeze Agents to Prevent Low-Temperature Stress in Vines by Yali Zhang, Mengyao Han, Langjie Wu, Haoyu Wang, Yanying Liang, Xianhang Wang, Zhumei Xi

“…Compared to the control (water), all four antifreeze agents significantly reduced the relative conductivity and malondialdehyde content in the tender shoots of both grape varieties, increased the Fv/Fm ratio, enhanced osmotic adjustment substance levels, and improved antioxidant enzyme activity. Moreover, relative conductivity and malondialdehyde content were significantly lower, and the Fv/Fm ratio was higher when the antifreeze agents were applied 24 h before frost compared to 48 h. …”
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Effect of DLPFC rTMS on anhedonia and alpha asymmetry in depressed patients by Reza Kazemi, Reza Rostami, Abed L. Hadipour, Ahmad Zandbagleh, Sanaz Khomami, Nasim Kiaee, John P. Coetzee, Angela Philips, Maheen Mausoof Adamson

“…BS and US both reduced anhedonia symptoms in the active compared to the sham group. Even non-responders in the BS group showed a decreased anhedonia. …”
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