Allosteric Fluorescent Detection of Saccharides and Biomolecules in Water from a Boronic Acid Functionalized Arene Ruthenium Assembly Hosting Fluorescent Dyes by Alaa Maatouk, Thibaud Rossel, Bruno Therrien

“…However, in the presence of naphthalene and pyrene, fluorescein⸦MR1 shows a different behavior, acting as an indicator displacement assay with the full recovery of fluorescence. …”
Get full text

Functionalized oligonucleotides, synthetic catalysts as enzyme mimics by Chardet, Crystalle, Serres, Sandra, Payrastre, Corinne, Escudier, Jean-Marc, Gerland, Béatrice

“…We will exemplify the development of FuON either presenting RNA-cleaving activity or acting as peroxidase or protease mimics and discuss the impact of the introduced modifications.…”
Get full text

Hepatitis C Virus Infection and Hospital-Related Outcomes: A Systematic Review by Michelle Ng, Patrizia Maria Carrieri, Lindila Awendila, Maria Eugenia Socías, Rod Knight, Lianping Ti

“…People living with hepatitis C infection (HCV) have a significant impact on the global healthcare system, with high rates of inpatient service use. Direct-acting antivirals (DAAs) have the potential to alleviate this burden; however, the evidence on the impact of HCV infection and hospital outcomes is undetermined. …”
Get full text

Towards Sustainability: Tracking Carbon Footprint Trends at Ezemvelo KZN Wildlife by Kgaphudi Wendy Madiope, Jacob Adedayo Adedeji, Sebataolo Rahlao

“…The findings of this study direct EKZNW toward ecologically conscious behaviors by acting as a catalyst for educated decision-making. …”
Get full text

SPATIAL PLANNING FOR RUBBER AND COFFEE DEVELOPMENT IN KONTUM PROVINCE by Nguyễn Duy Liêm, Trần Thị Mỹ Duyên

“…Thus, it can be seen that integration of the maximum limitation method of the FAO, cost-benefit analysis and GIS could be useful in quickly and accurately evaluating land for perennial agricultural crops, providing a scientific basis for the rational spatial planning of these crops and acting as a reference to land policy makers and land use planners.…”
Get full text

Prevalence of resistance-associated substitutions (RAS) in hepatitis C virus in the Former Soviet Union countries by Sten H Vermund, Salima Davlidova, Syed Hani Abidi, Syed Ali, Robert Heimer, Aidana Mustafa, Dinara Begimbetova

“…Objective The emergence of resistance-associated substitutions (RASs) poses a significant challenge to the effective treatment of hepatitis C virus (HCV) infection using direct-acting antivirals. This study’s objective was to observe the prevalence of HCV genotypes and RAS within the Former Soviet Union (FSU) countries.Methods We analysed 60 NS3, 313 NS5A and 1119 NS5B sequences of HCV deposited in open-access databases from 11 FSU countries for the prevalence of genotypes and the presence of RAS using the Geno2Pheno software.Results The following NS3 RASs were revealed through our analyses: 156P/S/T, 168del, 80K, 55A and 174S. …”
Get full text

Coupled Lateral and Torsional Vibration of Rub-Impact Rotor during Hovering Flight by Nan Zheng, Moli Chen, Guihuo Luo, Zhifeng Ye

“…When aircraft make a maneuvering during flight, additional loads acting on the engine rotor system are generated, which may induce rub-impact faults between the rotor and stator. …”
Get full text

The Empire of Amir Timur and His Political Successors: Kipchaks in Social and Administrative Structures by Rustam A. Abdumanapov

“…The considered sources attest to representatives of Kipchak tribes were close enough to associates of Amir Timur and would hold high positions, acting as emirs of diwans, tuvachis, emirs of tumens, seal keepers, etc. …”
Get full text

Subregional pedoclimatic conditions with contrasted UV-radiation shape host-microbiome and metabolome phenotypes in the grape berry by Viviana Martins, Cécile Abdallah, António Teixeira, Carolina Moreira, Márcio Nóbrega, Arnaud Lanoue, Hernâni Gerós

“…Metabarcoding showed a trade-off between bacteria and fungal diversity among subregions, with Pseudomonas, Lactobacillus, Aspergillus and Penicillium acting as intraregional microbial markers. The high phenotypic plasticity of berries and the role of microbes in this process are relevant upon current projections for increased UV radiation and temperature in Southern European viticulture, in a climate change scenario, with predicted impacts on regional wine quality and on the development of adaptation strategies for resilient viticulture.…”
Get full text

Exploration of the Potential Mechanisms of Wumei Pill for the Treatment of Ulcerative Colitis by Network Pharmacology by Jinke Huang, Yijun Zheng, Jinxin Ma, Jing Ma, Mengxiong Lu, Xiangxue Ma, Fengyun Wang, Xudong Tang

“…The drug-ingredient-target gene network revealed 52 active ingredients of WMP acting on 73 targets related to UC. GO analysis revealed that biological processes were mainly associated with oxidative stress, such as, reactive oxygen species metabolic processes, response to oxidative stress, cellular response to oxidative stress, response to reactive oxygen species, and regulation of reactive oxygen species metabolic processes. …”
Get full text

Numerical study on a supercritical vortex drop shaft with a spiral inlet by Gaetano Crispino, Filomena Maietta, Michele Iervolino, Corrado Gisonni

“…New insights on the pressure forces acted by the swirling flow across the vertical shaft were also provided. …”
Get full text

Resolution of depression: Antidepressant actions of resolvins by Satoshi Deyama, Katsuyuki Kaneda, Masabumi Minami

“…Although recent studies have demonstrated that ketamine, an N-methyl-D-aspartate receptor antagonist, produces rapid antidepressant effects in treatment-resistant patients, it also has undesirable side effects. Hence, rapid-acting antidepressants that have fewer adverse effects than ketamine are urgently required. …”
Get full text

Can Superabsorbent Polymers Improve Plants Production in Arid Regions? by Mohsen Jahan, Mehdi Nassiri Mahallati

“…Superabsorbent polymers (SAPs) have shown to be quite effective and useful in acting as a reservoir for water and some nutrients in arid and semiarid regions. …”
Get full text

Lewy body diseases and the gut by Timothy R. Sampson, Malú Gámez Tansey, Andrew B. West, Rodger A. Liddle

“…Experimental LBD models have implicated important contributions from the intrinsic gut microbiome, the intestinal immune system, and environmental toxicants, acting as triggers and modifiers to GI pathologies. …”
Get full text

Behavior of platinum in the system of the matte-slag in the processing of copper-nickel materials by Amdur A., Selivanov E., Fedorov S., Pavlov V., Krasikov S.

“…The conditions for the rise of a matte drop, together with a bubble in the slag, consist in the fact that the adhesive force of the drop with the bubble and the buoyancy force acting on the bubble must be greater than the gravity of the drop.…”
Get full text

Peran Dokter sebagai Saksi Ahli Di Persidangan by Rika Susanti

“…In providing expert information, the doctor should follow the applicable provisions in Council of Indonesia, so it is important for the doctor to know the ordinances and the attitude of doctors acting as medical witnesses.<br />Keywords: Doctors as medical expert witnesses,legal basis, court, guidelines for expert witness.…”
Get full text

Bacterial Exopolysaccharides as Reducing and/or Stabilizing Agents during Synthesis of Metal Nanoparticles with Biomedical Applications by Carlos Enrique Escárcega-González, Javier A. Garza-Cervantes, Augusto Vázquez-Rodríguez, José Rubén Morones-Ramírez

“…In this context, bacterial EPSs have been explored as agents to aid in a greener production of a myriad of metal nanoparticles, since they have the ability to reduce metal ions to form nanoparticles and stabilize them acting as capping agents. In addition, by incorporating EPS to the metal nanoparticles, the EPS confers them biocompatibility. …”
Get full text

Seismic Responses and Damage Mechanisms of Deep-Buried Underground Powerhouse in Layered Rock Mass by Meng Zhao, Ming Xiao, Juntao Chen, Hancheng Jin

“…It can convert the seismic wave input problem into the problem of solving equivalent nodal force acting on the artificial boundaries. Based on the characteristics of dynamic interaction between interlayers in layered rock mass, an explicit dynamic contact force method considering the seismic deterioration effect and bond-slip characteristics of interface is also presented to simulate various contact states such as bond, separation, and sliding. …”
Get full text

Role of nitric oxide synthase on brain GABA transaminase activity and GABA levels by Vega Rasgado Lourdes A., Reyes Guillermo Ceballos, Vega Díaz Fernando

“…Different effects of NO on GABA-T activity and on GABA levels, depending on the NOS isoform involved, may explain its contradictory role in seizures, the endothelial NOS acting as an anticonvulsant and the neuronal NOS as a proconvulsant. nNOS inhibitors may represent a new generation of antiepileptics.…”
Get full text

Dual AAV/IL-10 Plus STAT3 Anti-Inflammatory Gene Delivery Lowers Atherosclerosis in LDLR KO Mice, but without Increased Benefit by Maohua Cao, Junaid A. Khan, Bum-Yong Kang, Jawahar L. Mehta, Paul L. Hermonat

“…Both IL-10 and STAT3 are in the same signal transduction pathway, with IL-10-bound IL10 receptor (R) acting through STAT3 for anti-inflammatory effect. …”
Get full text