An Emerging New Paradigm in Opioid Withdrawal: A Critical Role for Glia-Neuron Signaling in the Periaqueductal Gray by Handong Ouyang, Shue Liu, Weian Zeng, Roy C. Levitt, Keith A. Candiotti, Shuanglin Hao

“…Accumulating evidence suggests that glial activation leading to the release of proinflammatory molecules acting on neurons is important in the complex syndrome of opioid dependence and withdrawal. …”
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Tramadol Induced Adrenal Insufficiency: Histological, Immunohistochemical, Ultrastructural, and Biochemical Genetic Experimental Study by Shereen Abdelhakim Abdelaleem, Osama A. Hassan, Rasha F. Ahmed, Nagwa M. Zenhom, Rehab A. Rifaai, Nashwa F. El-Tahawy

“…Tramadol is a synthetic, centrally acting analgesic. It is the most consumed narcotic drug that is prescribed in the world. …”
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Time-varying 3D optical torque via a single beam by Yi-Jing Wu, Jing-Han Zhuang, Pan-Pan Yu, Yi-Fan Liu, Zi-Qiang Wang, Yin-Mei Li, Cheng-Wei Qiu, Lei Gong

“…Here, we demonstrate full control of the 3D optical torque acting on a trapped microparticle by tailoring the vectorial SAM transfer. …”
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Simeprevir and Sofosbuvir Combination Treatment in a Patient with HCV Cirrhosis and HbS Beta 0-Thalassemia: Efficacy and Safety despite Baseline Hyperbilirubinemia by Nikolaos Papadopoulos, Melanie Deutsch, Athanasios Georgalas, Helias Poulakidas, Lazaros Karnesis

“…She was considered as illegible for pegylated-interferon-free treatment with direct acting antivirals and a course with simeprevir and sofosbuvir (SOF) combination for twelve weeks was planned. …”
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A Bi‐level stacked LSTM‐DNN‐based decoder network for AGC dispatch under regulation market framework in presence of VPP and EV aggregators by Kingshuk Roy, Sanjoy Debbarma, Siddhartha Deb Roy, Liza Debbarma

“…Abstract The consideration of mileage settlement in the frequency regulation market has encouraged fast‐acting units, such as converter‐interfaced generators (CIG) and electric vehicle stations, to actively participate in load‐generation balancing through automatic generation control (AGC). …”
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BeSnake: A Routing Algorithm for Scalable Spin-Qubit Architectures by Nikiforos Paraskevopoulos, Carmen G. Almudever, Sebastian Feld

“…Employing a simple breadth-first search approach, beSnake effectively manages the restrictions created by diverse topologies and qubit positions acting as obstacles for up to 72% qubit density. …”
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Role of Opioid Ligands in the Irritable Bowel Syndrome by Enrico Corazziari

“…The kappa receptor agonist fedotozine exerts its antinociceptive effect by acting on peripheral nerve endings of sensory vagal and nonvagal afferent pathways. …”
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Willingness-to-pay to access Ingenol Mebutate Gel for Actinic Keratosis Treatment in the U.S. Setting by Michael Willis, Sandra Erntoft, Sofie Persson, Jenny M. Norlin, Ulf Persson

“…**Conclusions:** Patients diagnosed with AK indicated an unmet need for fast-acting topical treatment with shorter LSR resolution time.…”
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The dawn of preventing respiratory syncytial virus lower respiratory tract infections in children by Z Dangor, S A Madhi, H Zar, D Demopoulos

“…Recently, two new RSV prevention strategies have emerged: nirsevimab, a long-acting monoclonal antibody, and a maternal RSV vaccine. …”
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Does Ménière's Disease in the Elderly Present Some Peculiar Features? by R. Teggi, A. Meli, M. Trimarchi, F. LiraLuce, M. Bussi

“…Particularly, the lower rate of migrainous history and positivity for autoantibodies often associated with MD, in our opinion, support the hypothesis of a vascular disorder acting as a predisposing factor for MD in elderly.…”
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Integrated gene expression and alternative splicing analysis in human and mouse models of Rett syndrome by Silvia Gioiosa, Silvia Gasparini, Carlo Presutti, Arianna Rinaldi, Tiziana Castrignanò, Cecilia Mannironi

“…MeCP2 is a global gene expression regulator, acting at transcriptional and post-transcriptional levels. …”
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Phosphate valorization by dry chlorination route by Kanari N., Menad N., Diot F., Allain E., Yvon J.

“…Reaction rate of Ca2P2O7 by Cl2+CO+N2 at 950°C is slowed down due to the formation of a CaCl2 liquid layer acting as a barrier for the diffusion of the reactive gases and further reaction progress. …”
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Research on the Development Approach for Reusable Model in Parallel Discrete Event Simulation by Jianbo Li, Yiping Yao, Wenjie Tang, Feng Zhu

“…By standardizing model’s external interfaces, Reusable Component Model Framework (RCMF) achieves the model reusability acting as an interface specification. However, the RCMF model is presently developed just through manual programing. …”
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India’s Policies in Support of the New Space by I. V. Danilin, E. P. Shavlay

“…We use comparative analysis to assess the current state and prospects of the industry and its possible implications for the Indian global positions.The study shows that New Delhi aims to embrace new realities amidst ambitious economic targets, social challenges, and growing geopolitical tensions with China, with the pandemic acting as a catalyst. Thanks to innovative measures, India has already become one of the central space players, but it still falls short of leadership in the New Space due to its resourceconstrained and state-centered course. …”
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Nurses’ Behaviors, Perceptions and Diagnoses in the Diagnosing Phase of the Nursing Process within the Scope of a Case Study: A Mixed Type Study by Arzu Akman Yılmaz, Ahu Çırlak

“…Introduction: The nursing process is a systematic, dynamic problem-solving process that expresses the way of thinking and acting that nurses use in performing their practices.Aim: It aims to examine nurses' perceptions of nursing diagnoses, their behaviors regarding the diagnosis phase, and their ability to identify appropriate diagnoses within the scope of a case study.Method: 103 nurses working in a private hospital in Ankara participated in the study. …”
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Further Developments of Bessel Functions via Conformable Calculus with Applications by Mahmoud Abul-Ez, Mohra Zayed, Ali Youssef

“…We establish several important formulas of the fractional Laplace Integral operator acting on the CFBFs of the first kind. With this in hand, we discuss the solutions of a generalized class of fractional kinetic equations associated with the CFBFs in view of our proposed fractional Laplace transform. …”
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Opicapone, a Novel Catechol-O-methyl Transferase Inhibitor, for Treatment of Parkinson's Disease "Off" Episodes by Amnon A. Berger, Ariel Winnick, Jonathan Izygon, Binil M. Jacob, Jessica S. Kaye, Rachel J. Kaye, Elisa E. Neuchat, Adam M. Kaye, Edward S. Alpaugh, Elyse M. Cornett, Andrew H. Han, Alan D. Kaye

“…Opicapone is a novel, peripherally acting Catechol-O-methyl transferase (COMT) inhibitor that is used as adjunctive therapy to carbidopa/levodopa for treatment and prevention of "off episodes." …”
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The Correlation Between Electrodiagnostic Severity and Patient-Reported Disability Among Carpal Tunnel Syndrome Patients by Gülay Soykök, Emel Güler

“…Conclusion: In addition to the electrophysiological data, self-report measures may help to pursue a multidirectional approach in patient management by acting as a reference for the diagnosis, treatment, and monitoring of CTS. …”
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A comprehensive review on integrated photo rechargeable batteries- supercapacitors, and their techno-economic feasibility by Jyoti Bhattacharjee, Subhasis Roy

“…The importance and impact of photoactive nanomaterials acting as photoelectrodes in embedded photo batteries result from their structure, topology, and pertinent for photo charging and Li-ion storage; this photo battery uses highly photosensitive two-dimensional lead halide perovskites. …”
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Criminal law sanctions for misappropriation, embezzlement or seizure of property through abuse of office by I. I. Cherkashyn, Yu. V. Filei

“…It has been concluded that a sanction is a mandatory component of an article (or part of an article) of the Special Part of the Criminal Code of Ukraine which contains a model of the type and scope of punishment which is adequate to the social danger of a criminal act. The sanction reveals the legal aspect of criminal punishment, indicating its type and scope, while acting as a model of criminal punishment provided for the crime. …”
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