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7841
Transgressive hybrids as hopeful holobionts
Published 2025-01-01“…In extreme cases, the effects of hybridization can transcend ecological timescales by introducing trait novelty upon which evolution can act. Indeed, hybridization can even have macroevolutionary consequences, for example, as a driver of adaptive radiations and evolutionary innovations. …”
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7842
Dual Role of α-MSH in Colitis Progression: Mediating Neutrophil Differentiation via Bone Marrow
Published 2025-02-01“…Additionally, we used flow cytometry, adeno-associated virus-mediated gene silence, parabiosis and single-cell RNA sequencing to uncover the specific roles and mechanisms of the HPA in colitis.Results: Our results indicate that colitis activates HPA secretion and increases α-MSH. α-MSH acts on the MC5R present on the surface of hematopoietic stem cells (HSCs) in the bone marrow, altering the bone marrow microenvironment and promoting HSCs proliferation and differentiation into neutrophils. …”
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7843
Exploring the Impact of Homophily Attitude, Physical, and Social Attractiveness on Purchase Intentions
Published 2024-03-01“…FindingsThe findings indicate that trustworthiness acts as a mediator in the relationship between Homophily attitude, physical and social attractiveness, and purchase intention. …”
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7844
Feasibility study of an experimental social space-oriented rehabilitation concept for people with intellectual and/or multiple disabilities: a study protocol
Published 2025-01-01“…In line with this, the German Federal Participation Act has further developed the relevant disability policy at the national level. …”
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7845
The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Cont...
Published 2025-01-01“…The use of biologically active components derived from various sources, including minerals, synthetic materials, plants, and organic compounds, has a long history in the development of hemostatic agents. These components can act through various mechanisms, such as inducing platelet aggregation, activating the coagulation cascade, or promoting the formation of blood clots. …”
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7846
Financial Cost of Treating Polytrauma in a Public Tertiary Hospital in the South-Eastern Democratic Republic of Congo: A Case Series Study
Published 2025-02-01“…The study was based on the operational definitions of Heinrich and the economic burden of care at the individual level was calculated by dividing the average direct costs by the GDP per capita, PPP of the country.Results: The present study comprised forty patients with polytrauma, with a mean age of 29.73 ± 9.9 years, ranging from 9 to 45 years.Approximately 65% of cases were attributed to road accidents, with a male predominance of 82.5%.The most frequently observed form of vital distress was neurological, accounting for 60% of cases, and le parage chirurgical comme acte chirurgical (28.11%). The overall survival rate was 7.50%, with a mean direct cost per patient of USD 608.77 ± 370.85 (range: USD 139.78 to USD 1826.34). …”
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7847
Mechanism of <italic>Coptis chinensis</italic> in Treatment of Type 2 Diabetes Mellitus Based on Network Pharmacology and Molecular Docking
Published 2021-12-01“…In terms of cell components (CC), it involved the composition of enzyme regulated complex, cystic cavity, membrane microregion and membrane region. ③ Components-target-pathway network analysis showed that, the main potential active ingredients of <italic>Coptis chinensis</italic> in the treatment of type 2 diabetes mellitus were quercetin, berberine, etc. It can act on mitogen-activated proteinase 1 (MAPK1), serine/threonine protein kinase (AKT1), tumor protein p53 (TP53), transcription factor AP-1 (JUN), tumor necrosis factor (TNF), interleukin-6 (IL-6), which can regulate MAPK, AGEs-RAGE, PI3K-Akt, Toll-like receptors, HIF-1, TNF signaling pathways, etc. ④ The molecular docking results showed that, the molecular docking affinity between the active ingredients of <italic>Coptis chinensis</italic> and the above core targets was less than -7.0 kcal/mol (1 kca/mol=4.186 kJ/mol), and the binding activity was better.Conclusion<italic>Coptis chinensis</italic> may play an important role in the treatment of type 2 diabetes mellitus and its complications by regulating glucose and lipid metabolism, inflammatory response, cell proliferation and apoptosis and promoting oxidative stress, etc.…”
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7848
Compound weather and climate extremes in the Asian region: science-informed recommendations for policy
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7849
Anti-thermal-quenching and colour-tuneable Tb3+/Ce3+-doped phosphor from natural wollastonite
Published 2024-12-01“…In the xTb3+/0.06Ce3+/xLi+ (0.01 ≤ x ≤ 0.09) co-doped wollastonite phosphors, Ce3+ acted as a sensitizer and the energy transfer efficiency from Ce3+ to Tb3+ reached 62.5%. …”
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7850
Standards in Neurological Rehabilitation, June 1997
Published 1997-01-01“…The EFNS Task Force would be pleased to assist in the publication of such deliberations or to act as a focus for international education and research or for sharing of examples of good practice.…”
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7851
Lowering light intensity while extending photoperiod at a constant daily light integral synergistically interacts with warm temperature to enhance leaf expansion and crop yield in...
Published 2025-01-01“…IntroductionLow light intensity and far-red (FR) light act as shade signals to induce specific morphological changes mediated by plant photoreceptors phytochromes (PHYs). …”
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7852
Microbial assisted alleviation of nickel toxicity in plants: A review
Published 2025-01-01“…Nickel (Ni) is required in trace amounts (less than 500 µg kg−1) in plants to regulate metabolic processes, the immune system, and to act as an enzymatic catalytic cofactor. Conversely, when nickel is present in high concentration, it is considered as a toxic substance. …”
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7853
Aesthetic Transformation of Morsal (Simple) Prose Texts with an Emphasis upon Semantics
Published 2022-03-01“…Stylistic studies of Morsal prose texts revealed that the aesthetic aspects of such works rely on the content of language, within which syntactic elements act as a rhetorical device and give the works aesthetic value. …”
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7854
WORLD EXPERIENCE IN ADMINISTRATIVE AND LEGAL SUPPORT OF FOOD SECURITY
Published 2024-12-01“…The government has adopted a number of laws, regulations, acts and measures to improve food security and economic sustainability. …”
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7855
Humanities education reform exploration and practice under outcomes-based education (OBE)
Published 2020-03-01“…The curricula, educational process, its methods, tools are adjusted, rebuilt and replaced if they do not contribute to the development of such skills, e. g. the results of the training determine its system and act not as a goal, but as a means of achieving it. …”
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7856
Assessing the Causal Relationship Between Various Immune Cells and Attention Deficit Hyperactivity Disorder: Mendelian Randomization Study
Published 2025-01-01“…Immune cell phenotypes that may act as a safeguard against ADHD included CD3 on resting Treg (OR = 0.925, 95% CI = 0.888–0.963, p = 1.5E−4) and SSC‐A on monocytes (OR = 0.951, 95% CI = 0.924–0.980, p = 8.5E−4), among others. …”
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7857
Sistem Berbasis Private Blockchain sebagai Penyedia Layanan Autentikasi Publisher-Broker-Subscriber Pada Protokol Message Queue Telemetry Transport
Published 2022-08-01“…With Ethereum blockchain user can upload a smart contract to the blockchain that acts as a mini program. Because of this the writer propose to make a smart contract that functions as an authentication server. …”
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7858
Les Jeunes Tunisiens, une contre-expérience de la minoration ? Politisation des langues dans la presse francophone en Tunisie coloniale (1907-1912)
Published 2022-06-01“…The status of the language was based on Tunisian actors who needed French to act as intermediaries and to occupy official positions within the colonial administration. …”
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7859
The Predictive Value of Growth Differentiation Factor-15 in Recurrence of Atrial Fibrillation after Catheter Ablation
Published 2020-01-01“…Our study indicated increased preprocedural GDF-15 is associated with left atrial remodeling and acts as a predictor of AF recurrence after ablation.…”
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7860
La mort de l’auteur selon Friedrich Kittler
Published 2018-01-01“…Une partie de la littérature ne se préoccupe plus d’ouvrir à un monde de l’imagination accessible par-delà les lettres écrites, et explore au contraire l’écriture automatique ou le pouvoir de signifiants qui font obstacle à l’intentionnalité de l’acte d’écriture. Mais un auteur qui ne se reconnaît plus dans ce qu’il écrit est-il encore un auteur ? …”
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