Teachers’ responses to racism and racist bullying in Dutch primary schools by Karen M. A. Sieben-Aduful, Roy A. Willems, Trijntje Völlink, Nico van der Wiel, Maria Sapouna, Pieter de Bruijn, Gemma Blok, Gemma Blok, Arjan E. R. Bos, Arjan E. R. Bos, Giel van Lankveld

“…BackgroundEarly in life, children with a non-White skin color, or a non-Western cultural or religious background, are susceptible of experiencing acts of racism. Since they spend a significant time of their daily life in school, teachers have a crucial role in providing a safe and bias-free environment for these children. …”
Get full text

Oxidative balance scores and gallstone disease: mediating effects of oxidative stress by HaoPeng Zhu, Lei Jin, Zhe Zhang, Chao Lu, QiTao Jiang, YiPing Mou, WeiWei Jin

“…Conclusions A higher OBS is associated with a reduced risk of GSD, especially among higher education levels groups, and albumin, uric acid may act as mediators of this association. These findings underscore the potential role of oxidative stress in GSD and the significance of maintaining a healthy diet and lifestyle to decrease GSD risk.…”
Get full text

Designing a Model of Effective Factors on Creative Cultural Industries in Iran by Abbas Ghaedamini Harouni, Mehrdad Sadeghi Deh Cheshmeh, Sadegh Sadeghi Deh Cheshmeh, Narjes Mohsenifar

“…Therefore, a model of influential factors in creative cultural industries should be designed to produce new value audiences, properly use knowledge and technology, and act purposefully to create cultural products and services.…”
Get full text

Isolation, identification and characteristics of Aeromonas sobria from diseased rainbow trout (Oncorhynchus mykiss) by Li-Ping Liu, Li-Ping Liu, Ying-Dong Fang, Peng-Tian Kang, Xiang-Yun Gao, Guo-Wei Zhang, Jing Pan, Jia Lu, Ji-Xing Liu, Wang-Dong Zhang

“…In addition, eight virulence genes were screened from strain As012, including Act, Aer, AexT4, Alt, ahyB, ascV, Nuc and Hly. The strain As012 can grow in the environment with pH 1–11, temperature 8–43°C and NaCl concentration 0–8%. …”
Get full text

Antioxidant Effect of Beer Polyphenols and Their Bioavailability in Dental-Derived Stem Cells (D-dSCs) and Human Intestinal Epithelial Lines (Caco-2) Cells by Marina Di Domenico, Antonia Feola, Pasqualina Ambrosio, Federica Pinto, Giovanni Galasso, Armando Zarrelli, Giovanni Di Fabio, Marina Porcelli, Salvatore Scacco, Francesco Inchingolo, Lucio Quagliuolo, Andrea Ballini, Mariarosaria Boccellino

“…In the presence of an intense stressing event, cells activate specific responses to counteract cell death or senescence which is known to act as a key-task in the onset of age-related pathologies and in the loss of tissue homeostasis. …”
Get full text

Time-Restricted Feeding Reinforces Gut Rhythmicity by Restoring Rhythms in Intestinal Metabolism in a Jetlag Mouse ModelSummary by Hui Leng, Theo Thijs, Louis Desmet, Guillaume Vanotti, Mona Farhadipour, Inge Depoortere

“…Conclusions: This pioneering transcriptomic study demonstrates that TRF acts as a robust entrainer during chronic jetlag, realigning disturbances in the circadian clock and the transcriptome involved in metabolic functions in the jejunal mucosa. …”
Get full text

Thioredoxin‐interacting protein (TXNIP) is a substrate of the NEDD4‐like E3 ubiquitin‐protein ligase WWP1 in cellular redox state regulation of acute myeloid leukemia cells by Sara Giovannini, Yanan Li, Rosalba Pecorari, Claudia Fierro, Claudia Fiorilli, Federica Corigliano, Valeria Moriconi, Ji Zhou, Anna De Antoni, Artem Smirnov, Sara Rinalducci, Anna Maria Timperio, Massimiliano Agostini, Jinping Zhang, Yufang Shi, Eleonora Candi, Gerry Melino, Francesca Bernassola

“…The HECT‐type E3 ubiquitin WWP1 (also known as NEDD4‐like E3 ubiquitin‐protein ligase WWP1) acts as an oncogenic factor in acute myeloid leukemia (AML) cells. …”
Get full text

Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma Neurospheres by Natália Hogetop Freire, Alice Laschuk Herlinger, Julia Vanini, Matheus Dalmolin, Marcelo A. C. Fernandes, Carolina Nör, Vijay Ramaswamy, Caroline Brunetto de Farias, André Tesainer Brunetto, Algemir Lunardi Brunetto, Lauro José Gregianin, Mariane da Cunha Jaeger, Michael D. Taylor, Rafael Roesler

“…Valproic acid (VPA) is an antiepileptic drug that acts partially by inhibiting histone deacetylases (HDACs) and could be repurposed as an epigenetic anticancer therapy. …”
Get full text

Self-beneficial transactional social dynamics for cooperation in Shwachman-Diamond syndrome: a mixed-subject analysis using computational pragmatics by Arthur Trognon, Arthur Trognon, Arthur Trognon, Natacha Stortini, Natacha Stortini, Coralie Duman, Coralie Duman, Nami Koïdé, Ewa Skupinska, Ewa Skupinska, Hamza Altakroury, Alizée Poli, Alizée Poli, Loann Mahdar-Recorbet, Loann Mahdar-Recorbet, Blandine Beaupain, Jean Donadieu, Michel Musiol, Michel Musiol, Michel Musiol

“…Using computational pragmatics, we aimed to identify the underlying principles guiding their social behavior.MethodsA cohort of 10 children (5 SDS, 5 matched controls) participated in ecological and cognitive tasks, including the WISC-V “Comprehension” subtest, NEPSY-II social perception tasks, and the Trognon Ecological Side Task for the Assessment of Speech-Act Processing (TEST-ASAP). Dialogues were analyzed using the Topological and Kinetic (2TK) model and a Recurrent Neural Network (RNN), enabling fine-grained computational insights into their interaction patterns.ResultsChildren with SDS exhibited cooperative behaviors shaped by perceived economic benefits, often at the expense of established social norms. …”
Get full text

Striatal-cortical dysconnectivity underlies somatosensory deficits in Parkinson's disease: Insights from rhythmic auditory-motor training by Cheng-Wei Huang, Hsin-Yun Tsai, Yi-Hsuan Lin, Wen-Wei Lin, Chin-Hsien Lin, Ming-Tsung Tseng

“…Rhythmic auditory-motor training acts to recover striatal connectivity, improving PD patients' somatosensory deficits.…”
Get full text

Nociceptor-localized KCC2 suppresses brachial plexus avulsion-induced neuropathic pain and related central sensitization by Hang Xian, Huan Guo, Yuan-Ying Liu, Sui-Bin Ma, Rui Zhao, Jian-Lei Zhang, Hang Zhang, Rou-Gang Xie, Xu-Cheng Guo, Jie Ren, Sheng-Xi Wu, Ceng Luo, Rui Cong

“…The synthesis and release of brain-derived neurotrophic factor (BDNF) was also proved reduction through overexpression of KCC2 in DRG, which indicates BDNF can also act as the downstream role in this pain state. As in human-derived tissues, we found decreased expression of KCC2 and increased expression of BDNF and TrκB in avulsed roots of BPA patients compared with normal human DRGs. …”
Get full text

Transcriptomic analysis of Medicago truncatula calli with MtWOX9-1 overexpression by V. E. Tvorogova, E. Y. Krasnoperova, A. A. Kudriashov, K. A. Kuznetsova, E. A. Potsenkovskaya, Y. A. Fedorova, L. A. Lutova

“…These genes  are putative targets of MtWOX9-1, and they may act in the same pathway with this regulator during SE.…”
Get full text

Enhanced energy storage performance in Ag(Nb,Ta)O3 films via interface engineering by Xiao Zhai, Jun Ouyang, Weijie Kuai, Yinxiu Xue, Kun Wang, Nengneng Luo, Hongbo Cheng, Hanfei Zhu, Chao Liu, Limei Zheng

“…A Ag(Nb,Ta)O3/BaTiO3 bilayer film is proposed, where the BaTiO3 layer acts as a p-type semiconductor while Ag(Nb,Ta)O3 layer is n-type, together with the n-type LaNiO3 buffer layer on the substrate, forming an n-p-n heterostructure. …”
Get full text

The association of sexual frequency with cardiovascular diseases incidence and all-cause mortality by Tian-Qi Teng, Jing Liu, Meng-Meng Wang, De-Gang Mo, Rui Chen, Jia-Chao Xu, Zi-Han Dong, Ning Zhang, Hai-Chu Yu

“…After adjusting for confounders, sexual frequency was found to be associated with CVD incidence and all-cause mortality among young and middle-aged individuals. Those with sexual acts less than 12 times/year faced the highest risks of CVD incidence and all-cause mortality, as frequency increased, the risks gradually decreased, reaching a nadir at approximately 52–103 times/year, but then a negative correlation began to emerge. …”
Get full text

CCL-2 and CXCL-8: Potential Prognostic Biomarkers of Acute Kidney Injury after a Bothrops atrox Snakebite by Juliana Costa Ferreira Neves, Hiochelson Najibe Santos Ibiapina, Fábio Magalhães-Gama, Jacqueline Almeida Gonçalves Sachett, Iran Mendonça Silva, Kerolaine Fonseca Coelho, Eliane Campos Alves, Andréa Monteiro Tarragô, Luiz Carlos de Lima Ferreira, Adriana Malheiro, Wuelton Marcelo Monteiro, Allyson Guimarães Costa

“…These soluble immunological molecules act by modulating the inflammatory response; however, the mechanisms associated with the development of AKI are still poorly understood. …”
Get full text

RETRACTED: The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model by Yukihiro Hiramatsu, Koichiro Suzuki, Takashi Nishida, Naoki Onoda, Takashi Satoh, Shizuo Akira, Masahito Ikawa, Hiroko Ikeda, Junzo Kamei, Sandra Derouiche, Makoto Tominaga, Yasuhiko Horiguchi

“…Bradykinin induced by LOS sensitized a transient receptor potential ion channel, TRPV1, which acts as a sensor to evoke the cough reflex. Vag8 further increased bradykinin levels by inhibiting the C1 esterase inhibitor, the major downregulator of the contact system, which generates bradykinin. …”
Get full text

Prescribed Minimum Benefits complaints: a five-year retrospective review by Lindelwa Mitchele Ngobeni, Lucky Moropeng, Evelyn Thsehla

“… Background: No matter which benefit option members have chosen, medical schemes are required by the Medical Schemes Act no. 131 of 1998 to pay costs associated with the diagnosis, treatment, or care of a specified set of benefits known as Prescribed Minimum Benefits (PMBs). …”
Get full text

GDNF family receptor alpha-like (GFRAL) expression is restricted to the caudal brainstem by Cecilia Hes, Lu Ting Gui, Alexandre Bay, Fernando Alvarez, Pierce Katz, Tanushree Paul, Nadejda Bozadjieva-Kramer, Randy J. Seeley, Ciriaco A. Piccirillo, Paul V. Sabatini

“…Objective: Growth differentiation factor 15 (GDF15) acts on the receptor dimer of GDNF family receptor alpha-like (GFRAL) and Rearranged during transfection (RET). …”
Get full text

Plasma Asprosin Levels Are Associated with Glucose Metabolism, Lipid, and Sex Hormone Profiles in Females with Metabolic-Related Diseases by Xing Li, Mingyu Liao, Rufei Shen, Linlin Zhang, Hua Hu, Jun Wu, Xiuli Wang, Hua Qu, Shaodong Guo, Min Long, Hongting Zheng

“…Binary logistic regression analysis revealed that plasma asprosin level acted as an independent risk factor for T2DM or PCOS. …”
Get full text

Default mode network-basal ganglia network connectivity predicts the transition to postherpetic neuralgia by Ying Wu, Chao Wang, Wei Qian, Lieju Wang, Lina Yu, Minming Zhang, Min Yan

“…Conclusions: Our results provide evidence that DMN-BGN connectivity during the acute period confers a risk for the development of chronic pain and can act as a neuroimaging biomarker to predict the outcome of patients with HZ.…”
Get full text