The Effect of Alcoholism on Food Security in Rural Areas: A Case Study of Bufundi Subcounty Rubanda District Uganda. by Natukunda, Ruth

“…The study recommends that; there is a need to enormously implement government policies such as the New Alcohol Control Bill 2016 of the Liquor Act, Cap. 93 which prohibits the selling of alcohol anywhere in Uganda to persons below 18 years without a license and this will reduce alcoholic beverages to the community members which reduces their income.…”
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The Use of Orature in the Depiction of the Conflict Between the Luo and the Lang’o in the Play Lwanda Magere by Okoiti Omtatah. by Tayebwa, Shyness

“…The play Lwanda Magere acts as the main research instrument and the use of documentary guides has been successfully incorporated. …”
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Supervision and Employee Performance: A Case Study of Lyamujungu SACCO Kabale District. by Atukunda, Emily

“…Lastly, the study revealed that there is a relationship between supervision and employee performance as supervision is an extremely vital part of a workplace, poor supervision leads to limited responsibility for taking action for the prevention of problems, mistakes, accidents, and injuries, poor supervision also opens the door for unethical behaviors within a company, effective supervision in workplaces acts as a motivating factor and increases job satisfaction, offering employee’s feedback on their work is an effective way of monitoring their progress, individual meetings between supervisors and their employees, poor supervision doesn’t only mean that there isn’t enough supervision, supervision entails overseeing the activities of the junior members to ensure that they are in line with an organization’s policies, supervision for subordinates increases employee productivity and overall performance. …”
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Performance Management Innovations and Local Government Employees Performance in Kabale District: A case Study of Kabale District Local Government Administration. by Alex, Museveni

“…The study found out that performance management innovations employed to improve employee’s performance include Various Acts and statutory guidelines ,Local governments need for constant feedback from service-users , The White Paper on Local Government, conforming to Integrated Development Plan (IDP) framework , broader framework in place to improve financial management in local government and development of a guide, that performance management innovations have improved employee’s performance in the following ways: Review of the performance of staff, regular review meetings have increased, targets have been maintained, submission of reports, that the Challenges met during the implementation of performance management innovations are, Difficulty in measuring performance, The lack of clear roles and responsibilities, Political factors, non-performance culture and Organizational factors. …”
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Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma by Zihao Deng, Lixia Liu, Guantai Xie, Zhenming Zheng, Jieyou Li, Wenchong Tan, Yaotang Deng, Jinxin Zhang, Manfeng Liang, Yingxia Wu, Zhifeng Zhou, Yan Li, Yukui Chen, Yaling Huang, Hairou Su, Guibing Wu, Xiongjie Shi, Shengpei Cen, Yandan Liao, Yilin Liu, Fei Zou, Xuemei Chen

“…Heat shock protein 90 (Hsp90) acts as a chaperone to maintain the stability and activity of the client proteins. …”
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Pac-Man-Shaped Patch-Driven Broadband Circularly Polarized Metasurface Antenna With CMA-Based Quadruple-Mode Excitation by Deepak K. Naik, Dhruba Charan Panda, Rajanikanta Swain, Arjuna Muduli, Sambhudutta Nanda

“…For a quadruple-mode excitation, the antenna uses a unique pac-man-shaped patch (PSP) as the primary CP radiator and above it a <inline-formula> <tex-math notation="LaTeX">$4\times 4$ </tex-math></inline-formula> sized rectangular MTS, which acts as the secondary radiator. Characteristic mode analysis (CMA)-based mode manipulation approach facilitates effortless separation of two orthogonal modes (OMs) of PSP, creating a 90&#x00B0; phase difference for circular polarization. …”
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Development of face image recognition algorithm using CNN in airport security checkpoints for terrorist early detection by Eca Indah Anggraini, Fachdy Nurdin, Mohammad Obie Restianto, Sudarti Dahsan, Andini Aprilia Ardhana, Asep Adang Supriyadi, Yahya Darmawan, Syachrul Arief, Agus Haryanto Ikhsanudin

“…Ensuring airport security is of paramount importance to safeguard the lives of passengers and prevent acts of terrorism. In this context, developing advanced technology for early terrorist detection is crucial. …”
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Expectorant Effects of <i>Atractylodes japonica</i> Koidz. ex Kitam Root Extracts on Particulate Matter-Induced Pulmonary Injury in Mice by Junho Lee, Sana Mansoor, Jeongjun Lee, Hunsuk Chung, Young-Sam Kwon, Khawaja Muhammad Imran Bashir, Jae-Suk Choi, Sae-Kwang Ku

“…The results of this study highlight the fact that AJ could act as a promising alternative for respiratory protection, with potential applications as a functional food ingredient. …”
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Hopping backward to move forward: Single-leg backward hopping can better detect decreased quadriceps strength induced by a fatigue protocol compared to forward and vertical hopping by Yu Song, Lauren Salsgiver, Kaden Van Valkenburg, Natalie Christofferson, Yessica Lo, Zhichen Feng, Brenna McGuinness, Boyi Dai

“…Conclusion: The greater sensitivity of the backward hopping to detect quadriceps fatigue suggests it may act as a better or at least an additional metric to evaluate quadriceps strength deficits. …”
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Biochemical Properties of the Acid Ectophosphatase Activity of <i>Phytomonas serpens</i> Involved in Cell Proliferation by Luiz Fernando Carvalho-Kelly, Anita Leocadio Freitas-Mesquita, Thaís Souza Silveira Majerowicz, José Roberto Meyer-Fernandes

“…Given that <i>P. serpens</i> can uptake inorganic phosphate (P_i) from the extracellular medium, it is likely that its ectophosphatase activity acts together with the transport systems in the P_i acquisition process. …”
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Freedom of expression, aspiration and gender: A cultuling in the student demonstration by Siti Nurbayani, Elly Malihah, Millary Agung Widiawaty, Moh. Dede, Bayu Iqbal Anshari, Asep Mahpudz, Erry Sukriah, Sri Wahyuni

“…Men and women demonstrators style their messages differently, but both express shared feelings of frustration and disappointment with the government and its policies. Speech acts that used creative linguistic strategies, emotional expressions that ranged from anger to satirical critique, and cultural values that reflected complex societal dynamics of power, gender, and social resistance. …”
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Tailoring Borate Mediator Species Enables Industrial CO Production with Improved Overall Energy Efficiency by Sustainable Molten Salt CO2 Electrolysis by Xinyu Li, Bowen Deng, Kaifa Du, Wenmiao Li, Di Chen, Xin Qu, Fangzhao Pang, Xiaodan Zhang, Hao Zha, Huayi Yin, Dihua Wang

“…This system involved a series of well‐designed target borate species (BO33−, BO2−, and B4O72−) that acted as mediators shuttling between the cathode and anode, favoring CO as the primary cathodic product. …”
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Cross-cultural insights into internet addiction and mental health: a network analysis from China and Malawi by Mengze Li, Yidi Wang, Bin Liu, Xiaoli Ni, Zhujing Ma, Fengzhan Li, Tifei Yuan, Hongyi Chen, Zhongying Wu, Qiannan Jia, Lei Song, Yinchuan Jin, Qun Yang

“…Bridge symptoms varied between the countries, with functional impairments (school work, daily work suffering and difficult to make decision) being more prominent in Malawi and emotional disturbances (daily work suffering, act annoyed and difficult to enjoy) in China. Conclusions The study highlights significant differences in the network structures of internet addiction and mental health between China and Malawi, which underscore the importance of culturally sensitive mental health interventions. …”
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Protocol for the development of a global core outcome set for the surgical treatment of differentiated thyroid cancer: a literature review and international Delphi survey by Anton F Engelsman, Romana T Netea-Maier, Christiaan F Mooij, Robin P Peeters, Menno R Vriens, A S Paul van Trotsenburg, Schelto Kruijff, Joep P M Derikx, Faridi S Jamaludin, Daniël J van de Berg, Hanneke M van Santen, Sarah C Clement, Eveline Bruinstroop, Frederik A Verburg, Angelique Seur, Els J M Nieveen van Dijkum

“…The final COS will be reported in accordance with the COS-Standards for Reporting statement.Ethics and dissemination The medical research ethics committee of the Amsterdam UMC confirmed that the Dutch Medical Research Involving Human Subjects Act (WMO) does not apply to this study and that full approval by the committee is not required. …”
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Hyperlipidemia May Synergize with Hypomethylation in Establishing Trained Immunity and Promoting Inflammation in NASH and NAFLD by Charles I. V. Drummer, Fatma Saaoud, Yu Sun, Diana Atar, Keman Xu, Yifan Lu, Ying Shao, Candice Johnson, Lu Liu, Huimin Shen, Nirag C. Jhala, Xiaohua Jiang, Hong Wang, Xiaofeng Yang

“…We performed a panoramic analysis on both human nonalcoholic steatohepatitis (NASH) microarray data and microarray/RNA-seq data from various mouse models of nonalcoholic fatty liver disease NASH/NAFLD with total 4249 genes examined and made the following findings: (i) human NASH and NAFLD mouse models upregulate both cytokines and chemokines; (ii) pathway analysis indicated that human NASH can be classified into metabolic and immune NASH; methionine- and choline-deficient (MCD)+high-fat diet (HFD), glycine N-methyltransferase deficient (GNMT-KO), methionine adenosyltransferase 1A deficient (MAT1A-KO), and HFCD (high-fat-cholesterol diet) can be classified into inflammatory, SAM accumulation, cholesterol/mevalonate, and LXR/RXR-fatty acid β-oxidation NAFLD, respectively; (iii) canonical and noncanonical inflammasomes play differential roles in the pathogenesis of NASH/NAFLD; (iv) trained immunity (TI) enzymes are significantly upregulated in NASH/NAFLD; HFCD upregulates TI enzymes more than cytokines, chemokines, and inflammasome regulators; (v) the MCD+HFD is a model with the upregulation of proinflammatory cytokines and canonical and noncanonical inflammasomes; however, the HFCD is a model with upregulation of TI enzymes and lipid peroxidation enzymes; and (vi) caspase-11 and caspase-1 act as upstream master regulators, which partially upregulate the expressions of cytokines, chemokines, canonical and noncanonical inflammasome pathway regulators, TI enzymes, and lipid peroxidation enzymes. …”
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Science-based communication and education needed to improve forest carbon science, policy, and management outcomes by Chad C Papa, Kylie Clay, Lauren T Cooper, Scott C Stark

“…Because forests stand to play a significant role in reaching net-zero emission targets, politicians and policymakers must act decisively to engineer a rapid paradigm shift that maintains forests’ resilience and adaptive capacity. …”
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Overcoming hypoxia-induced breast cancer drug resistance: a novel strategy using hollow gold-platinum bimetallic nanoshells by Lian-Ying Zhang, Xiao-Tong Chen, Rong-Tian Li, Wei Meng, Guo-Qin Huang, Yong-Jian Chen, Feng-Jun Ge, Qun Zhang, Yu-Jun Quan, Cai-Tao Zhang, Yi-Fei Liu, Ming Chen, Jin-Xiang Chen

“…Specifically, we synthesized a hollow gold (Au)-platinum (Pt) bimetallic nanoshell for the first time, which acted as a drug delivery system (DDS) for doxorubicin (DOX). …”
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A new potential of sodium anthraquinone-2-sulfonate as a corrosion inhibitor for carbon steel in 0.5 M H2SO4 by Nikolay Akatyev, Roza Kenzhegalieva, Meruyet Khapiyeva, Gauhar Uzakbay, Aruzhan Talapova, Ruben Vardanyan

“…Analysis of dynamic polarization curves showed that AQ2SNa acts as an inhibitor of a mixed nature. The results also indicate that AQ2SNa significantly increases the contact angle, indicating increased hydrophobicity due to the formation of a stable film on the metal surface. …”
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Achieving chronic hepatitis B functional cure: Factors and potential mechanisms by Jiarui Zheng, Zilong Wang, Linxiang Huang, Zixuan Qiu, Yandi Xie, Suzhen Jiang, Bo Feng

“…Spontaneous clearance of HBsAg is rare, while NAs can directly inhibit HBV DNA, they are unable to act on covalently closed circular DNA (cccDNA), hence inhibiting HBsAg production or clearing HBsAg is extremely challenging. …”
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DNA methylation of ACADS promotes immunogenic cell death in hepatocellular carcinoma by Ze Qian, Yifan Jiang, Yacong Wang, Yu Li, Lin Zhang, Xiaofeng Xu, Diyu Chen

“…Conclusions Our work clarified that ACADS acts as a putative tumour suppressor in HCC and confirmed that a nomogram including ACADS methylation had good predictive performance in HCC. …”
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