Research on Correlations of lncRNA ST7-AS1 with Progression and Therapeutic Targets of Esophageal Cancer by Xiao Lin, Sijia Sun, JiWen Zhang, Yan Cai, Quan Cheng

“…Mechanistically, ST7-AS1 acted as a sponge for miR-4262, affecting the progression of esophageal cancer. …”
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Using Inverse Distance Weighting to Determine Spatial Distributions of Airborne Chemical Elements. Case Study: Douala, Cameroon by Joseph Magloire Fossokeng Mouafo, Claudiu Tănăselia, André Nana Yakam, Jules Richard Priso, Mohammed Ketata, Alexandru-Ionut Petrisor

“…These findings bring additional evidence that trees can act as bio-indicators and bio-accumulators in urban environments.…”
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The landscape of nucleotide diversity in Drosophila melanogaster is shaped by mutation rate variation by Barroso, Gustavo V, Dutheil, Julien Y

“…However, the mechanisms of evolution do not act in isolation, and integrative models that simultaneously consider the influence of multiple factors on diversity are lacking; without them, confounding factors lurk in the estimates. …”
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Development and Utilization of Domino Card Media in Thematic Learning of Mathematics for Elementary School Students by Siti Asiya, Khotibul Umam, Andi Suhardi, Alcher J. Arpilleda

“…Learning media attract students' attention and act as a conduit for messages between educators and students. …”
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Legal and Ethical Challenges of the Use of Nuclear Technologies in Space: Risks and Opportunities by Larysa Soroka, Anna Danylenko, Maksym Sokiran

“…In particular, it has been stated that the presence of a nuclear arsenal can act as a deterrent, forcing potential aggressors to reevaluate their actions. …”
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Plasma-derived exosomal miR-326, a prognostic biomarker and novel candidate for treatment of drug resistant pediatric acute lymphoblastic leukemia by Neda Saffari, Soheila Rahgozar, Elaheh Faraji, Fikrettin Sahin

“…Co-culture studies on drug resistant patient primary cells and B-ALL cell lines suggested that exosomes with high miR-326 level act as vehicles for reducing cells viability. B-ALL cell line transfection with naked miR-326 mimic confirmed the results, and fluorescence microscopy validated uptake and internalization of exosomes by target cells. …”
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Quantitative impact of immunomodulation versus oncolysis with cytokine-expressing virus therapeutics by Peter S. Kim, Joseph J. Crivelli, Il-Kyu Choi, Chae-Ok Yun, Joanna R. Wares

“…In addition, we found that combinations of specialist viruses that express either IL-12 or 4-1BBL might initially act more potently against tumors than a generalist virus that simultaneously expresses both, but the advantage is likely not large enough to replace treatment using the generalist virus. …”
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Quantifying forest disturbance regimes within caribou (Rangifer tarandus) range in British Columbia by James C. Maltman, Nicholas C. Coops, Gregory J. M. Rickbeil, Txomin Hermosilla, A. Cole Burton

“…Additionally, we utilize this data to investigate harvesting rates since the implementation of the Species at Risk Act (SARA) and publication of recovery strategies for caribou in BC. …”
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Design and Experimental Assessment of a 2D Microwave Imaging System for Brain Stroke Monitoring by Jorge A. Tobon Vasquez, Rosa Scapaticci, Giovanna Turvani, Gennaro Bellizzi, Nadine Joachimowicz, Bernard Duchêne, Enrico Tedeschi, Mario R. Casu, Lorenzo Crocco, Francesca Vipiana

“…The device is a 2D version of the 3D system, currently under construction, and consists of an array of 12 printed monopole antennas connected to a two-port vector network analyzer through a switching matrix so that each antenna can act as a transmitter or receiver, thereby allowing the acquisition of the entire multistatic multiview scattering matrix required for the imaging. …”
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Interleukin-6 and interleukin-6 receptor secretion by chronic lymphatic leukaemia and normal B lymphocytes: effect of PMA and PWM by I. Drucker, A. Klajman, M. Revel, Y. Manor, S. Ben-Efraim, D. Novick

“…The results are consistent with the view that B-CLL cells produce spontaneously IL-6 which could act in an autocrine fashion to cause shedding of surface IL-6R and account for the correlation found between serum levels of sIL-6R and B-CLL lymphocyte numbers. …”
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BMP4 Cooperates with Retinoic Acid to Induce the Expression of Differentiation Markers in Cultured Mouse Spermatogonia by Yongguang Yang, Yanmin Feng, Xue Feng, Shangying Liao, Xiuxia Wang, Haiyun Gan, Lixian Wang, Xiwen Lin, Chunsheng Han

“…In conclusion, BMP4 may exert autocrine effects and act cooperatively with RA to induce the differentiation of spermatogonia in vivo.…”
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Disappearance of the Polar Cap Ionosphere During Geomagnetic Storm on 11 May 2019 by H.‐J. Kwon, K.‐H. Kim, G. Jee, J. Seon, C. Lee, Y.‐B. Ham, J. Hong, E. Kim, T. Bullett, H.‐U. Auster, W. Magnes, S. Kraft

“…From these observations we suggest that transpolar ionospheric currents connected to the field‐aligned currents flowing on a substorm wedge‐shaped circuit act as a source of polar atmospheric heating during the moderate geomagnetic storm interval and that elevated heavy molecular gases (O2 and N2) by atmospheric heating contribute to the electron density depletion via increased recombination rate.…”
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Activation of Glycine and Extrasynaptic GABAA Receptors by Taurine on the Substantia Gelatinosa Neurons of the Trigeminal Subnucleus Caudalis by Thi Thanh Hoang Nguyen, Janardhan Prasad Bhattarai, Soo Joung Park, Seong Kyu Han

“…Taurine showed non-desensitizing and repeatable membrane depolarizations and inward currents which remained in the presence of amino-acid receptors blocking cocktail (AARBC) with tetrodotoxin, indicating that taurine acts directly on the postsynaptic SG neurons. Further, application of taurine at different doses (10 μM to 3 mM) showed a concentration dependent depolarizations and inward currents with the EC50 of 84.3 μM and 723 μM, respectively. …”
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Unraveling the Role of Ubiquitin-Conjugating Enzyme UBE2T in Tumorigenesis: A Comprehensive Review by Chang Gao, Yan-Jun Liu, Jing Yu, Ran Wang, Jin-Jin Shi, Ru-Yi Chen, Guan-Jun Yang, Jiong Chen

“…Increasing evidence suggests that UBE2T acts as an oncogene and could serve as a promising therapeutic target in cancer treatment. …”
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Gene Expression Profiling in Lungs of Chronic Asthmatic Mice Treated with Galectin-3: Downregulation of Inflammatory and Regulatory Genes by Esther López, M. Paz Zafra, Beatriz Sastre, Cristina Gámez, Carlos Lahoz, Victoria del Pozo

“…Suppressors of cytokine signaling (SOCS) proteins act as negative regulators of cytokine signaling. …”
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Rationalising blood tests in a resource-limited emergency unit: A quality improvement project by Renette Esterhuizen, Lilani I. Tribelhorn, Danielle M.J. Thomas, Eugenne Elliott, Talat Habib, Arun Nair

“…Methods: The Plan-Do-Study-Act (PDSA) method was employed. Pre- and post-intervention data were collected. …”
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GEORGIA'S ECONOMY IN THE SPACE OF CONTRADICTIONS BETWEEN REGIONAL POWERS by A. S. Degtev, A. Margoev, A. A. Tokarev

“…The CIS surpasses the EU in commodity turnover with Georgia, however it is in fact an amorphous organization that formally combines its member-states and lacks for common economic policy, unlike the European Union that acts as an integration association. Third, Chinese investment in Georgian infrastructure within the "New Silk Way" project serves as a ponderable alternative to Russian financial flow. …”
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Deregulation mechanisms and therapeutic opportunities of p53-responsive microRNAs in diffuse large B-cell lymphoma by Elena N. Voropaeva, Yuriy L. Orlov, Anastasia B. Loginova, Olga B. Seregina, Vladimir N. Maksimov, Tatiana I. Pospelova

“…Many of them play a crucial role in carcinogenesis and may act as oncogenes or suppressor of tumor growth. …”
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Microalga <i>Nannochloropsis gaditana</i> as a Sustainable Source of Bioactive Peptides: A Proteomic and In Silico Approach by Samuel Paterson, Laura Alonso-Pintre, Esperanza Morato-López, Sandra González de la Fuente, Pilar Gómez-Cortés, Blanca Hernández-Ledesma

“…Seven of twenty-seven peptides showed ≥20% intestinal absorption, suggesting potential systemic effects, while the rest could act at local level. Molecular docking demonstrated strong affinities with key enzymes such as MPO, ACE, and DPPIV. …”
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Immune-endocrine crossroads: the impact of nuclear receptors in Tuberculosis and Chagas disease by Ana R. Pérez, Ana R. Pérez, Oscar A. Bottasso, Oscar A. Bottasso, Oscar A. Bottasso, Natalia E. Santucci, Natalia E. Santucci

“…Nuclear Receptors (NRs) comprise a superfamily of proteins with essential roles in cell signaling, survival, proliferation, and metabolism. They act as transcription factors and are subclassified into families based on their ligands, DNA-binding sequences, tissue specificity, and functions. …”
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