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5921
Web-based interventions for fear of cancer recurrence: A scoping review with a focus on suggestions for the development and evaluation of future interventions.
Published 2024-01-01“…The most common theoretical framework for interventions is cognitive behavioural therapy (CBT), followed by mindfulness-based and mixed CBT, mindfulness, acceptance and commitment therapy (ACT), relaxation approaches. FCR was the primary focus/measure in 19 Studies, in 9 studies FCR was a secondary/related outcome/measure. …”
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5922
Meta-synthesizing of Practices of Corporate Social Responsibility: External Stake-holders Approach
Published 2024-06-01“…Additionally, the expectations of stakeholders compel banks not only to act ethically towards their suppliers and competitors but also to avoid any unethical practices. …”
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5923
Human Umbilical Cord-Derived Mesenchymal Stem Cell Therapy Ameliorates Nonalcoholic Fatty Liver Disease in Obese Type 2 Diabetic Mice
Published 2019-01-01“…The two conditions can act synergistically to produce adverse outcomes. …”
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5924
tiRNA-Gln-CTG is Involved in the Regulation of Trophoblast Cell Function in Pre-eclampsia and Serves as a Potent Biomarker
Published 2025-01-01“…Plasma from pregnant women with suspected PE was analyzed to assess the potential of tsRNA to act as a predictive marker of PE. …”
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5925
Mitochondrial Gene Expression of Three Different Dragonflies Under the Stress of Chlorpyrifos
Published 2025-01-01“…The present study underscores the response of mitochondrial gene expression in larvae of three different species in response to CPF pollutants, indicating that pesticide influences can potentially alter mitochondrial gene expression and potentially act as a method for assessing aquatic ecosystem health.…”
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5926
Understanding “Alert Fatigue” in Primary Care: Qualitative Systematic Review of General Practitioners Attitudes and Experiences of Clinical Alerts, Prompts, and Reminders
Published 2025-02-01“…However, not all CRs are acted upon, and many are disregarded by general practitioners (GPs), a chronic issue commonly referred to as “alert fatigue.” …”
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5927
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5928
Sport values and sustainability?
Published 2025-01-01“… Introduction United Nations call for all nations to act together towards the Sustainable Development Goals (SDGs) and recalls that this collective transformation requires the development of shared values into citizens that are in line with SDGs. …”
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5929
A workplace-based HIV self-testing intervention as a determinant for self-testing knowledge, beliefs, and use among unskilled workers in Wakiso Uganda
Published 2025-01-01“…Organizations, alongside HIV testing implementing partners, should awaken people operating in risky environments and those engaging in risky sexual acts on the threat of succumbing to HIV as this greatly increases HIVST and repeat testing.…”
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5930
Effects of Corporal Punishments on Pupils Learning of English in Selected Primary Schools in Kyanamira Sub-County Kabale District Western Uganda.
Published 2024“…The majority of respondents (51%) who agreed that corporal punishment to be used in primary schools came with the grounds that corporal punishment acted as a catalyst for motivating learners to study by themselves, enhance learners to close their studies, refrain learners from issues that break school laws as well as maintaining punctuality among learners. …”
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5931
Insights from a Pilot Study of Naloxone Education
Published 2019-12-01“…Results: Both the controlled and the experimental sessions increased participants’ confidence to use first aid skills, specific confidence in an overdose situation and willingness to act. The educators reported low levels of learner literacy, which may have affected the reliability of the data gathered. …”
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5932
Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury
Published 2025-01-01“…Here, we examine how hypoxia and IL-1β act in synergy to augment maladaptive proximal tubular epithelial cell (PTEC) repair in human CKD. …”
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5933
Long non-coding RNA Malat1 modulates CXCR4 expression to regulate the interaction between induced neural stem cells and microglia following closed head injury
Published 2025-01-01“…Results Our results indicated that Malat1 could act as a sponge of miR-139-5p to modulate the expression of CXCR4 that exerted significant influence on the immunoregulatory effects of iNSCs on the secretion of CXCL12, TNF-α and IGF-1 by activated microglia. …”
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5934
Shed antigen-induced blocking effect on CAR-T cells targeting Glypican-3 in Hepatocellular Carcinoma
Published 2021-04-01“…In animal models, mice carrying Hep3B xenograft tumors expressing sGPC3 exhibited a worse response to the treatment with CAR-T cells under both a low and high tumor burden. sGPC3 bound to CAR-T cells but failed to induce the effective activation of CAR-T cells. Therefore, sGPC3 acted as dominant negative regulators when competed with cell surface GPC3 to bind anti-GPC3 CAR-T cells, leading to an inhibitory effect on CAR-T cells in HCC.Conclusions We provide a proof-of-concept study demonstrating that GPC3 shedding might cause worse response to CAR-T cell treatment by competing with cell surface GPC3 for CAR-T cell binding, which revealed a new mechanism of tumor immune escape in HCC, providing a novel biomarker for patient enrolment in future clinical trials and/or treatments with GPC3-targeted CAR-T cells.…”
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5935
The palmitoyl-CoA ligase Fum16 is part of a Fusarium verticillioides fumonisin subcluster involved in self-protection
Published 2025-02-01“…FUM16 (palmitoyl-CoA ligase), FUM17, and FUM18 (ceramide synthases) enzymatically supplement ceramide biosynthesis, while FUM19 (ATP-binding cassette transporter) acts as a repressor of the FUM cluster. The evolutionary conservation of FUM15 (P450 monooxygenase) in Fusarium and Aspergillus FUM clusters is discussed, and its effect on extracellular FB1 levels in both native (F. verticillioides) and heterologous (Saccharomyces cerevisiae) hosts is highlighted. …”
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5936
MLL4 regulates postnatal palate growth and midpalatal suture development
Published 2025-01-01“…MLL4, also known as KMT2D, is a histone methyltransferase that acts as an important epigenetic regulator in various organogenesis programs. …”
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5937
NLRP3: a key regulator of skin wound healing and macrophage-fibroblast interactions in mice
Published 2025-01-01“…Supplementing NLRP3−/− conditioned media with PGE2 partially restored the impaired functions, suggesting that PGE2 acts as a downstream mediator of NLRP3-regulated macrophage-myofibroblast interactions. …”
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5938
RETRACTED: Long non‐coding RNA Sox2OT promotes coronary microembolization‐induced myocardial injury by mediating pyroptosis
Published 2022-06-01“…Compared with the sham group (1.05 ± 0.32), lncRNA Sox2OT level (4.41 ± 0.67) in the CME group was elevated (P < 0.05). Sox2OT acted as a competitive endogenous RNA (ceRNA) of miR‐23b to regulate TLR4. …”
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5939
Corrosion behavior of Fe amorphous/Al-12Si piston composites with core-shell structure
Published 2025-01-01“…Spherical Fe amorphous particles act as “balls bearings” during hot extrusion, enhancing flowability and promoting the formation of a core-shell structure FACS with uniform composition distribution, high relative density, and low porosity when doping with 2–10% Fe amorphous particles. …”
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5940
Calidad del cuidado de enfermería en la unidad de cuidados intensivos durante la COVID-19: estudio cualitativo
Published 2025-02-01“…The pandemic was a complex emotional event, with tensions between values and emotions, caused by precarious working conditions, increasing morbimortality, the feeling that sometimes the effort was not recognized, the moral anguish of feeling that one could not act according to one's own principles and the imperious decision of having to choose which patients to save and care for, which had a negative impact on the quality of care. …”
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