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5881
Utilisation of ChatGPT and other Artificial Intelligence tools among medical faculty in Uganda: a cross-sectional study [version 2; peer review: 1 approved, 2 approved with reserva...
Published 2025-01-01“…ChatGPT has the potential to revolutionize medical education as it acts as an interactive virtual tutor and personalized learning assistant. …”
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5882
CASC8 activates the pentose phosphate pathway to inhibit disulfidptosis in pancreatic ductal adenocarcinoma though the c-Myc-GLUT1 axis
Published 2025-01-01“…Furthermore, we demonstrate that CASC8 acts as a crucial regulator of the pentose phosphate pathway and disulfidptosis, thereby promoting PDAC progression.…”
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5883
Electrochemotherapy with bleomycin, oxaliplatin, or cisplatin in mouse tumor models, from tumor ablation to in situ vaccination
Published 2025-02-01“…Our aim was to determine if ECT can act as in situ vaccination and thereby induce an abscopal effect. …”
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5884
Characterization and fungicides sensitivity of Colletotrichum species causing Hydrangea macrophylla anthracnose in Beijing, China
Published 2025-01-01“…Based on morphological characteristics and phylogenetic analysis of six genomic loci including rDNA-ITS, ACT, TUB2, CAL, CHS-1, and GAPDH, these isolates were identified as belonging to six Colletotrichum species. …”
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5885
Nutritional and antioxidative characterization, antimicrobial and sensorial stability of flaxseed powder supplemented mutton patties
Published 2025-01-01“…Conclusively, owing to better potential of FP in improving the nutritional and microbial quality of mutton patties, the study further suggests its ability to act as a novel functional ingredient of choice in shelf-life extension of other food products.…”
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5886
Modulation of DAPK1 expression by its alternative splice variant DAPK1-215 in cancer
Published 2025-01-01“…Mechanistically, DEAD-Box Helicase 3 X-Linked (DDX3X) stabilized both DAPK1-215 and DAPK1 mRNAs, suggesting that DAPK1-215 may act by competing for DDX3X binding to modulate DAPK1 mRNA stability. …”
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5887
Planetary health education in undergraduate medical education in Germany: results from structured interviews and an online survey within the national PlanetMedEd Project
Published 2025-02-01“…BackgroundIn light of the accumulating evidence, awareness and urgency to act upon the three planetary crises – climate change, biodiversity loss, and pollution – the concept of Planetary Health underscores their profound implications for health and promotes actionable solutions to advance both wellbeing and ecological sustainability. …”
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5888
Clinical manifestations, para-clinical features and outcome of Iranian adults with respiratory syncytial virus (RSV) infection: a report from hospitalized patients
Published 2025-02-01“…We suggest that RSV infection may act as a secondary factor in decompensating pre-existing liver failure, which was present in certain patients with underlying conditions, potentially leading to life-threatening consequences.…”
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5889
Experimental infection of wild boars (Sus scrofa) with Rickettsia rickettsii and evaluation of the transmission potential to Amblyomma sculptum ticks
Published 2025-01-01“…Conclusions Wild boars seroconverted to Rickettsia spp. after being infested with R. rickettsii-infected A. sculptum; however, they did not develop bacteremia and did not act as competent amplifying hosts of R. rickettsii for A. sculptum ticks. …”
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5890
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5891
ANO7 expression in the prostate modulates mitochondrial function and lipid metabolism
Published 2025-02-01“…The findings suggest that ANO7 may act as a key regulator of cellular lipid metabolism and mitochondrial function in the prostate, shedding light on a previously unknown aspect of ANO7’s biology.…”
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5892
Size distribution of extracellular vesicles in pretreatment ascites and plasma is correlated with primary treatment outcome in advanced high-grade serous carcinoma
Published 2025-02-01“…Patients were treated with primary cytoreductive surgery followed by adjuvant chemotherapy (ACT) (N = 15) or NACT followed by interval debulking surgery (IDS) when optimal cytoreduction was not feasible (N = 22). …”
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5893
Transgressive hybrids as hopeful holobionts
Published 2025-01-01“…In extreme cases, the effects of hybridization can transcend ecological timescales by introducing trait novelty upon which evolution can act. Indeed, hybridization can even have macroevolutionary consequences, for example, as a driver of adaptive radiations and evolutionary innovations. …”
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5894
Dual Role of α-MSH in Colitis Progression: Mediating Neutrophil Differentiation via Bone Marrow
Published 2025-02-01“…Additionally, we used flow cytometry, adeno-associated virus-mediated gene silence, parabiosis and single-cell RNA sequencing to uncover the specific roles and mechanisms of the HPA in colitis.Results: Our results indicate that colitis activates HPA secretion and increases α-MSH. α-MSH acts on the MC5R present on the surface of hematopoietic stem cells (HSCs) in the bone marrow, altering the bone marrow microenvironment and promoting HSCs proliferation and differentiation into neutrophils. …”
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5895
Exploring the Impact of Homophily Attitude, Physical, and Social Attractiveness on Purchase Intentions
Published 2024-03-01“…FindingsThe findings indicate that trustworthiness acts as a mediator in the relationship between Homophily attitude, physical and social attractiveness, and purchase intention. …”
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5896
Financial Cost of Treating Polytrauma in a Public Tertiary Hospital in the South-Eastern Democratic Republic of Congo: A Case Series Study
Published 2025-02-01“…The study was based on the operational definitions of Heinrich and the economic burden of care at the individual level was calculated by dividing the average direct costs by the GDP per capita, PPP of the country.Results: The present study comprised forty patients with polytrauma, with a mean age of 29.73 ± 9.9 years, ranging from 9 to 45 years.Approximately 65% of cases were attributed to road accidents, with a male predominance of 82.5%.The most frequently observed form of vital distress was neurological, accounting for 60% of cases, and le parage chirurgical comme acte chirurgical (28.11%). The overall survival rate was 7.50%, with a mean direct cost per patient of USD 608.77 ± 370.85 (range: USD 139.78 to USD 1826.34). …”
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5897
Anti-thermal-quenching and colour-tuneable Tb3+/Ce3+-doped phosphor from natural wollastonite
Published 2024-12-01“…In the xTb3+/0.06Ce3+/xLi+ (0.01 ≤ x ≤ 0.09) co-doped wollastonite phosphors, Ce3+ acted as a sensitizer and the energy transfer efficiency from Ce3+ to Tb3+ reached 62.5%. …”
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5898
Standards in Neurological Rehabilitation, June 1997
Published 1997-01-01“…The EFNS Task Force would be pleased to assist in the publication of such deliberations or to act as a focus for international education and research or for sharing of examples of good practice.…”
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5899
Lowering light intensity while extending photoperiod at a constant daily light integral synergistically interacts with warm temperature to enhance leaf expansion and crop yield in...
Published 2025-01-01“…IntroductionLow light intensity and far-red (FR) light act as shade signals to induce specific morphological changes mediated by plant photoreceptors phytochromes (PHYs). …”
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5900
Microbial assisted alleviation of nickel toxicity in plants: A review
Published 2025-01-01“…Nickel (Ni) is required in trace amounts (less than 500 µg kg−1) in plants to regulate metabolic processes, the immune system, and to act as an enzymatic catalytic cofactor. Conversely, when nickel is present in high concentration, it is considered as a toxic substance. …”
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