Company's diversification strategy and crash risk stock prices emphasizing operational slack and management ability by Majid Moradi, Roqaye Talebi, Hamid Reza Pakdaman

“…And according to the third hypothesis, management ability strengthens the negative relationship between diversification strategy and the risk of falling stock prices, not confirmed.Originality/Value: From the aspect of research innovation, we can mention the following: first, it showed that the diverse operations of companies act as a factor in reducing the risk of their collapse, thereby clarifying a new reason for companies to expand their operational scope. …”
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OVERCOMING THE ANTINOMIES OF HUMAN EXISTENCE: ONTOLOGY OF TRICKSTER by T. V. Danylova

“…This mediator is a trickster – bipolar character (good and evil at the same time). A trickster freely acts in unordered world of Chaos without Life – Death limitations. …”
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The synergistic effects of recycled polyethylene terephthalate fiber and fly ash on the ductility of one-part geopolymer stabilized soft soil by Zihan Zhou, Guo Hu, Qiang Zhu, Chuanqin Yao, Jun Wu

“…Additionally, FA in the OPG binder not only acted as a dispersant but also altered the orientation of PET fiber relative to the crack front. …”
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Genetic diversity of the immunoglobulin heavy chain locus in cohorts of patients affected with SARS-CoV-2 by Patrizia Malaspina, Carla Jodice, Bianca Maria Ciminelli, Michela Biancolella, Vito Luigi Colona, Andrea Latini, Francesca Leonardis, Paola Rogliani, Antonio Novelli, Giuseppe Novelli, Andrea Novelletto

“…Conclusions Two haplotypes seem to act as protective factors specifically in young individuals, counteracting the general increase in vulnerability with age. …”
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lncRNA SNHG15 as a ceRNA modulates Osteoclast Differentiation, Proliferation, and Metastasis by Sponging miR-381-3p/NEK2 Axis by YiFan Wang, GuanYin Zhu, Fang Pei, ZhiHe Zhao

“…Knockdown of miR-381-3p reversed the inhibitory effect of knockdown of NEK2 on the proliferation, migration, and differentiation of THP-1 cells induced by M-CSF/RANKL. Conclusion. SNHG15 acted as a ceRNA promoted the proliferation, migration, and differentiation of THP-1 cells induced by M-CSF/RANKL through sponging miR-381-3p to promote the expression of NEK2.…”
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System of Administrative and Legal Regulation of the Status of the Cabinet of Ministers of Ukraine in the Field of Scientific, Research and Technical Activity in Ukraine by V. S. Tarasenko

“…Thus, the mechanism of administrative and legal regulation of the status of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activities in Ukraine can be presented as follows: – administrative and legal norms that determine the administrative and legal status of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activities in Ukraine, their sources; – principles of the activity of the Cabinet of Ministers of Ukraine in the sphere of administrative relations in the field of science and technology in Ukraine; – interpretation of administrative and legal norms regulating the administrative and legal status of the Cabinet of Ministers of Ukraine in the field of scientific and scientific and technical activities in Ukraine; – the nature of administrative and legal relations in the field of scientific, research and technical activities, the participant of which is the Cabinet of Ministers of Ukraine; – individual acts of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activity; – forms of activity of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activity as the participant of administrative and legal relations; – methods of administrative and legal regulation of the status of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activities in Ukraine; – administrative and legal regimes regulating the status of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activities in Ukraine; – administrative procedures of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activities; – efficiency of administrative and legal regulation of the status of the Cabinet of Ministers of Ukraine in the field of scientific, research and technical activity.…”
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Distance Learning For Military Doctors in Crisis Situations: The DILEMMA Cross-Sectional Study Results by Nataliia Sydorova, Valerii Savytskyi, Taras Kuts

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ADAM-10 Regulates MMP-12 during Lipopolysaccharide-Induced Inflammatory Response in Macrophages by Yan Jiang, Qiming Gong, Jinmei Huang, Yuanxun Gong, Qiang Tang, Dalong Wei, Qianli Tang, Jingjie Zhao, Jian Song, Lingzhang Meng

“…Flow cytometry and immunofluorescence staining revealed that EX-ADAM 10 cells had increased iNOS expression, which acted as an IL-6 expression driver. In summary, we found that ADAM-10 is activated by LPS and positively participates in LPS-stimulated macrophage inflammatory responses by positively regulating MMP-12 during the inflammatory process.…”
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Regional Exploration and Characterisation of CO2 Storage Prospects in the Utsira-Skade Aquifer, North Viking Graben, North Sea by C. Lloyd, M. Huuse, B. J. Barrett, A. M. W. Newton

“…Other intra-aquifer mudstones were mainly interpreted to act as baffles to flow. Structural traps at the top Utsira and Skade Fms. yield fifteen prospects, with criteria of > 700 m depth and FRT storage capacity of > 5 Mt CO2. …”
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Immoral misdemeanor incompatible with the continuation of work as a ground for termination of the employment contract at the initiative of the owner or authorized body by V. V. Sychova

“…Emphasis is placed on the inexpediency of outlining at the legislative level an exhaustive list of acts that should be regarded as immoral, given their evaluative nature. …”
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ucumeropsis mannii seed oil protects against Bisphenol A- induced testicular mitochondrial damages by Patrick Maduabuchi, Aja, Hilary Akobi, Ogwoni, Peter Chinedu, Agu, Ejike Ugbala, Ekpono, Joshua Nonso, Awoke, Oliver Ugochukwu, Ukachi, Obasi Uche, Orji, Boniface Anthony, Ale, Chinonso Peter, Nweke, Esther Ugo, Alum, Darlington C., Chukwu, Christian E., Offor, Atamgba Agbor, Asuk, Ejike, Daniel Eze, Ojochenemi E., Yakubu, J. B., Akob, Onyedika Gabriel, Ani, Chinaza Godswill, Awuchi

“…here has been increasing search for the ameliorative properties of seed oils against toxicants. bisphenol A acts as an estrogenic endocrine-disrupting chemical capable of causing male infertility. …”
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The Impact of Sex Education Towards Moral Development Among Pupils in Kebisoni Sub-County Rukungiri District. by Kamagara, Annet

“…According to the findings, 100% of the respondents agreed that there are the impact of sex education towards moral development among pupils in the Kebisoni sub-county Rukungiri district and these included sexuality education is not damaging to children or adolescents, sexuality education open attitude towards sexuality among youth, provides a more robust framework for developing and measuring sex, children are aware of and recognize these relationships long before they act on their sexuality, provides adolescents with the information and skills they need to navigate relationships. …”
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The Impact of ICT on Student's Academic Performance in Selected Secondary Schools in Kabale District: A Case Study of Katuna Town Council. by Muzahura, Onesmus

“…The factors affecting the implementation of ICT study programmes in secondary schools, included; lack of qualification development, insufficient financing, lack of support from school I organisation or management, shortage of time and limited accessibility whereas the possible solutions to the challenges included political decisions, support from the school management committee, teachers should act as learners, time issue, peer support and increasing funding. …”
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MRTX1133 attenuates KRASG12D mutated-colorectal cancer progression through activating ferroptosis activity via METTL14/LINC02159/FOXC2 axis by Junwei Zou, Xiuhua Shi, Zhaoying Wu, Siyuan Zuo, Xiaolei Tang, Hailang Zhou, Yong Huang

“…In vitro and in vivo experiments suggest that LINC02159 acts as a tumour suppressor in CRC progression. Specifically, LINC02159 knockdown negated the inhibitory effects of MRTX1133 on tumourigenesis and its promotive effect on ferroptosis in KRASG12D-mutated CRC cells. …”
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Bioinorganic Synthesis of Polyrhodanine Stabilized Fe3O4/Graphene Oxide in Microbial Supernatant Media for Anticancer and Antibacterial Applications by Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Navid Omidifar, Maryam Zarei, Sonia Bahrani, Khadije Yousefi, Wei-Hung Chiang, Aziz Babapoor

“…Consequently, based on the results, it can be concluded that this novel polyrhodanine-based nanocompound can act as drug carriers due to their low toxic effects and may open a new window on the antibacterial agents.…”
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Normalization of tumor vasculature by imiquimod: proposal for a new anticancer therapeutic indication for a TLR7 agonist by Jarosz-Biej Magdalena, Czapla Justyna, Ciepła Joanna, Smolarczyk Ryszard, Drzyzga Alina, Sprus-Lipka Dorota, Pilny Ewelina, Matuszczak Sybilla, Cichoń Tomasz

“…Abstract Imiquimod (IMQ), a drug from aminoquinoline group, is the toll-like receptor 7 (TLR7) agonist. It acts as an immunostimulant and radio-sensitizing agent. …”
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MicroRNA-140-5p inhibits cellular proliferation, migration and invasion by downregulating AKT/STAT3/NF-κB pathway in breast carcinoma cells by Hou Lingli, Liu Qi, Zhao Ying, Yang Hongwei, Meng Qingying, Yu Fei

“…Taken the present study results together, we can conclude that miR-140-5p may act as a novel target in microRNA-targeting anticancer strategy for the treatment of breast cancer.…”
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Effect of Reforestation Tree Species on the Distribution and Stability of Purple Soil Aggregates by ZHONG Yujian, HE Feng, HAN Guangzhong, ZHAO Xia, YANG Fan

“…[Conclusion] The weathering of purple soil following afforestation provides the material foundation for aggregate formation, while the humus formed in the soil of artificial forests acts as a binding agent, promoting the formation of large aggregates and the maintenance of their stability.…”
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Metabolic Profiling by UPLC–Orbitrap–MS/MS of Liver from C57BL/6 Mice with DSS-Induced Inflammatory Bowel Disease by Zhongquan Xin, Zhenya Zhai, Hongrong Long, Fan Zhang, Xiaojun Ni, Jinping Deng, Lunzhao Yi, Baichuan Deng

“…Spearman correlation analysis showed that the majority of the biomarkers have a significant correlation with cytokines (TNF-α, IL-1β, IL-6, and IL-10), indicating that those biomarkers may act as potential targets to interact directly or indirectly with cecropin A and antibiotics to affect liver inflammation. …”
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Synergistic anti-oxidative/anti-inflammatory treatment for acute lung injury with selenium based chlorogenic acid nanoparticles through modulating Mapk8ip1/MAPK and Itga2b/PI3k-AKT... by Huizhen Xing, Xinwei Bai, Xiaoying Pei, Yuqi Zhang, Xueying Zhang, Shujun Chen, Dan Li, Bin Lv, Xiaoying Wang, Xiaoli Wu

“…Further mechanistic research revealed that CHSe NPs directly acted on and modulated the expression of Mapk8ip1 and Itga2b, which were upstream proteins of MAPK signaling pathway and PI3K-Akt signaling pathway, therefore impeding the cyclic synergy between oxidative stress and inflammatory dysregulation. …”
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