Role of TNF-Alpha, IFN-Gamma, and IL-10 in the Development of Pulmonary Tuberculosis by Yone Vila Nova Cavalcanti, Maria Carolina Accioly Brelaz, Juliana Kelle de Andrade Lemoine Neves, José Candido Ferraz, Valéria Rêgo Alves Pereira

“…In the process of control of the infection by mycobacteria, TNF-alpha seems to have a primordial function. This cytokine acts in synergy with IFN-gamma, stimulating the production of reactive nitrogen intermediates (RNIs), thus mediating the tuberculostatic function of macrophages, and also stimulating the migration of immune cells to the infection site, contributing to granuloma formation, which controls the disease progression. …”
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Seismic Random Noise Suppression Using Optimal ANFIS as an Adaptive Self-Tuning Filter and Wavelet Thresholding by K. Geetha, Malaya Kumar Hota

“…These parameters are determined optimally using the Honey badger algorithm with mean square error value as an objective function. Here, OANFIS acts as an adaptive self-tuning filter that extracts the appropriate seismic signal information without any knowledge of the amount of noise in the contaminated signal. …”
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Examining Examples and Elements of Illegal Competition and Anti-Competitive Practices with an Emphasis on the Resulting Civil Liability by Leila Ghaemi, Hossein Ghorbanian, Alireza Hasani

“…In this research, first the examples and elements of these acts and then the civil responsibility resulting from them are examined. …”
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Novel Antibiotic Combinations of Diverse Subclasses for Effective Suppression of Extensively Drug-Resistant Methicillin-Resistant Staphylococcus aureus (MRSA) by Shumyila Nasir, Muhammad Sufyan Vohra, Danish Gul, Umm E Swaiba, Maira Aleem, Khalid Mehmood, Saadia Andleeb

“…Levofloxacin-ceftazidime acted synergistically in 80% of the tested clinical MRSA isolates. …”
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Heterogeneity in Seed Samples from Vineyards and Natural Habitats Along the Eurasian <i>Vitis vinifera</i> Range: Implications for Domestication and Hybridization by Diego Rivera, Javier Valera, David Maghradze, Maia Kikvadze, Anna Nebish, Rafael Ocete, Carlos Álvar Ocete, Claire Arnold, Emilio Laguna, Francisco Alcaraz, Diego José Rivera-Obón, Gianni Lovicu, Massimino Farci, Concepción Obón

“…The study identified mixed populations across the Iberian Peninsula, Italy, and the South Caucasus, which act as significant gene reservoirs. A domestication gradient is evident, with higher domestication rates in the South Caucasus compared to Western Europe and East Asia. …”
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Intestinal Helminth Infections Among Domesticated Cats in Malate, Manila, Philippines by Jan Michael Chan, Mary Jane Flores, Eligio Santiago Maghirang, Helenar Chan

“…Due to the zoonotic potential of some intestinal helminths, cats, and other mammalian species with direct contact to humans may act as reservoir hosts and provide a medium for the transmission of zoonotic infections. …”
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Antioxidant and anti-inflammatory roles of tea polyphenols in inflammatory bowel diseases by Van-Long Truong, Woo-Sik Jeong

“…This review focuses on established antioxidant and anti-inflammatory properties of tea polyphenols and underlying mechanisms of their involvement in inflammatory bowel diseases (IBD). Tea polyphenols act as efficient antioxidants by inducing an endogenous antioxidant defense system and maintaining intracellular redox homeostasis. …”
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Studies on the biological effects of ozone: 8. Effects on the total antioxidant status and on interleukin-8 production by V. Bocci, G. Valacchi, F. Corradeschi, G. Fanetti

“…This is in line with the current idea that hydrogen peroxide, as a byproduct of O3 decomposition, acts as a messenger for the cytokine induction.…”
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Multistability Analysis and Function Projective Synchronization in Relay Coupled Oscillators by Ahmad Taher Azar, Ngo Mouelas Adele, Kammogne Soup Tewa Alain, Romanic Kengne, Fotsin Hilaire Bertrand

“…The second aspect of this study presents the synchronization of systems that act as mediators between two dynamical units that, in turn, show function projective synchronization (FPS) with each other. …”
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Aquathermolysis of heavy oil catalyzed by transition metal salts and clay by Du, Yingna, Zhang, Liyuan, Jing, Rui, Li, Yongfei, Yang, Bo, Chen, Gang

“…Therefore it is reasonable to believe that the minerals in reservoirs may act as a catalyst support with the metal-containing catalyst added from outside during the thermal recovery of heavy oil. …”
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Synthesis, Characterization and Antimicrobial Activity of Mixed Schiff Base Ligand Complexes of Co(II), Ni(II), Cu(II) and Zn(II) by A. K. Mapari, M. S. Hate, K. V. Mangaonkar

“…The resulting complexes were characterized by elemental analysis, thermogravimetric analysis, magnetic moment measurements, conductivity measurements, 1H NMR, IR, UV-visible and ESR spectral studies. The Schiff bases acts as bidentate monobasic ligands, coordinating through deprotonated phenolic oxygen and azomethine nitrogen atoms. …”
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Distribution and composition of redox-active species and dissolved organic carbon in Arctic lacustrine porewaters by Danhui Xin, Jeffrey M. Hudson, Anthony Sigman-Lowery, Yu-Ping Chin

“…In lacustrine porewaters, many redox-active species exist in their reduced form, while DOC acts as a substrate and an electron acceptor. Understanding the types and abundance of redox-active species in porewaters along with their complementary DOC substrate is pivotal for gaining insights into benthic processes, particularly in regions susceptible to climate change. …”
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Beliefs about Pedophilia and the Attribution of Punishment for Child Sexual Abusers by Gabriela GROZA, Codruța Anamaria RÎNDAȘU

“…However, when thinking about people with pedophilic sexual interests, people often consider them abusers (even if they did not act against children and did not commit any offense). …”
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Blood Genome-Wide Transcriptional Profiles of HER2 Negative Breast Cancers Patients by Ovidiu Balacescu, Loredana Balacescu, Oana Virtic, Simona Visan, Claudia Gherman, Flaviu Drigla, Laura Pop, Gabriela Bolba-Morar, Carmen Lisencu, Bogdan Fetica, Oana Tudoran, Ioana Berindan-Neagoe

“…Tumors act systemically to sustain cancer progression, affecting the physiological processes in the host and triggering responses in the blood circulating cells. …”
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Finite Element Modelling Based Studies for Dental Implants: Systematic Review by Shahad Mohammed Shakir, Saja Ali Muhsin, Raad Al Marza

“…Finite element methods not only give speedy and reliable data on the patients under investigation, but they also act as essential guidance for many clinical trials. …”
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Nutrition Therapy for Liver Diseases Based on the Status of Nutritional Intake by Kenichiro Yasutake, Motoyuki Kohjima, Manabu Nakashima, Kazuhiro Kotoh, Makoto Nakamuta, Munechika Enjoji

“…Moreover, addition of some nutrients that act to suppress viral proliferation is recommended. …”
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Antibacterial properties of substituted phenethylamine-based β-lactam derivatives in oral infections by Merve Yildirim, Elif Aksakal, Taha Yasin Bayram, Eda Irmak, Harun Gun, Bunyamin Ozgeris, Arzu Gormez

“…Streptococcus and Lactobacillus bacteria are the primary causative agents in dental caries. These bacteria act as opportunistic pathogens, potentially leading to serious diseases. …”
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Computational Study of Trisindoline 5 Against Overexpressed EGFR Protein on Breast Cancer Stem Cell by Nurhayati A.P.D., Fatoni M., Santoso M., Wati F.A.

“…The existing inhibitory drugs used to treat the EGFR that act as the master regulator of the signaling network still have a limited response in breast cancer. …”
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Tumor Site‐Specific In Vivo Theranostics Enabled by Microenvironment‐Dependent Chemical Transformation and Self‐Amplifying Effect by Yunfei Zuo, Pei Li, Wen‐Jin Wang, Changhuo Xu, Shuting Xu, Herman H. Y. Sung, Jianwei Sun, Guorui Jin, Weiping Wang, Ryan T. K. Kwok, Jacky W. Y. Lam, Ben Zhong Tang

“…Remarkably, TQ‐HA also acts as a self‐amplifier, autocatalytically activating TQ‐H2 by generating ·OH under light exposure. …”
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Evidence of Presynaptic Localization and Function of the c-Jun N-Terminal Kinase by Silvia Biggi, Lucia Buccarello, Alessandra Sclip, Pellegrino Lippiello, Noemi Tonna, Cristiano Rumio, Daniele Di Marino, Maria Concetta Miniaci, Tiziana Borsello

“…By means of modelling design, we found that JNK, via the JBD domain, acts as a physiological effector on T-SNARE proteins; then using biochemical approaches we demonstrated the interaction between Syntaxin-1-JNK, Syntaxin-2-JNK, and Snap25-JNK. …”
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