LRP1 involvement in FHIT-regulated HER2 signaling in non-small cell lung cancer by Théophile Ponchel, Emma Loeffler, Julien Ancel, Audrey Brisebarre, Nathalie Lalun, Véronique Dalstein, Anne Durlach, Gaëtan Deslée, Stéphane Dedieu, Myriam Polette, Béatrice Nawrocki-Raby

“…These results suggest that LRP1 acts downstream of HER2 to induce EMT and tumor progression following FHIT loss. …”
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Tumor CEMIP drives immune evasion of colorectal cancer via MHC-I internalization and degradation by Ying Zhu, Jiao Li, Tao Zhang, Lei Zhao, Min Jin, Jinghua Ren, Jing Tang, Haihong Wang, Zhenyu Lin, Qing Liang, Ruiqi Li, Biying Zhang, Qingling Hua, Guojie Xu, Jiayuan Chen, Lanqing Wang, Dejun Zhang, Dandan Yu

“…Mechanistically, CEMIP acted as an adaptor for the interaction betweenMHC-I and clathrin, which drove MHC-I internalization via clathrin-dependent endocytosis. …”
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Electroacupuncture Improves Cognitive Function in Senescence-Accelerated P8 (SAMP8) Mice via the NLRP3/Caspase-1 Pathway by Zhitao Hou, Ruijin Qiu, Qingshuang Wei, Yitian Liu, Meng Wang, Tingting Mei, Yue Zhang, Liying Song, Xianming Shao, Hongcai Shang, Jing Chen, Zhongren Sun

“…The aims of this study were to observe the effect of EA on cognitive function and explore the potential mechanism by which EA acts on the NLRP3/caspase-1 signaling pathway. Main Methods. …”
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The iGains4Gains model guides irrigation water conservation and allocation to enhance nexus gains across water, food, carbon emissions, and nature by Bruce Lankford, Nafn Amdar, Matthew McCartney, Tafadzwanashe Mabhaudhi

“…Second, with the insight that water conservation is a distributive/allocative act, we ask who between four paracommoners (the proprietor irrigation system, neighbouring irrigation systems, society, and nature) benefits hydrologically from changes in irrigation efficiency? …”
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Aquaponics model can provide better productivity: Microorganisms affect the growth and health of tilapia by Dingyue Fan, Huimin Xu, Shunlong Meng, Limin Fan, Chao Song, Liping Qiu, Dandan Li, Longxiang Fang, Zhuping Liu, Xuwen Bing

“…In the present study, three aquaponics systems were established, and three same sized recirculating aquaculture systems (RAS) were constructed to act as controls. To evaluate bacterial community diversity and compositions across different microhabitats in the two systems, we used amplicon-based high-throughput sequencing technique targeting the 16S rRNA gene. …”
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TGF-β3 Induces Autophagic Activity by Increasing ROS Generation in a NOX4-Dependent Pathway by Yun Zhang, Hong-Mei Tang, Chun-Feng Liu, Xie-Fang Yuan, Xiao-Yun Wang, Ning Ma, Guo-Feng Xu, Song-Ping Wang, Jun Deng, Xing Wang

“…The following study examined whether ROS act as upstream of autophagy activation in response to TGF-β3 induction. …”
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Gum Arabic (Acacia Senegal) Augmented Total Antioxidant Capacity and Reduced C-Reactive Protein among Haemodialysis Patients in Phase II Trial by Nour Elkhair Ali, Lamis AbdelGadir Kaddam, Suad Yousif Alkarib, Babikir Gabir Kaballo, Sami Ahmed Khalid, Abdalazim Higawee, Alaa AbdElhabib, Alaa AlaaAldeen, Aled O. Phillips, Amal Mahmoud Saeed

“…Gum Arabic (GA) has been claimed to act as an antioxidant and anti-inflammatory agent in experimental studies and clinical trials. …”
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Genetic interaction between oxidative stress and body mass index in a Spanish population by Francisco Lara-Hernández, Rebeca Melero, María Elena Quiroz-Rodríguez, Celeste Moya-Valera, Mariana de Jesús Gallardo-Espinoza, Luis Álvarez, Ingrid Lizeth Valarezo-Torres, Laisa Briongos-Figuero, Jessica Abadía-Otero, Francisco Javier Mena-Martin, Guillermo Saez, Josep Redon, Juan-Carlos Martín-Escudero, Ana-Bárbara García-García, Guillermo Ayala, Felipe Javier Chaves

“…Oxidative stress may act as a contributing factor in the development of an elevated body mass index (BMI). …”
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Interpretation of Recent Unrest Events (Bradyseism) at Campi Flegrei, Napoli (Italy): Comparison of Models Based on Cyclical Hydrothermal Events versus Shallow Magmatic Intrusive E... by A. Lima, R. J. Bodnar, B. De Vivo, F. J. Spera, H. E. Belkin

“…Bradyseism is governed by an impermeable shallow layer (B-layer), which is the cap of an anticlinal geological structure culminating at Pozzuoli, where maximum uplift is recorded. This B-layer acts as a throttling valve between the upper aquifer and the deeper hydrothermal system that experiences short (1-102 yr) timescale fluctuations between lithostatic/hydrostatic pressure. …”
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Metal-Based Antibacterial and Antifungal Agents: Synthesis, Characterization, and In Vitro Biological Evaluation of Co(II), Cu(II), Ni(II), and Zn(II) Complexes with Amino Acid-Der... by Zahid H. Chohan, M. Arif, Muhammad A. Akhtar, Claudiu T. Supuran

“…Ligands (L1)–(L5) were derived by condensation of β-diketones with glycine, phenylalanine, valine, and histidine and act as bidentate towards metal ions (cobalt, copper, nickel, and zinc) via the azomethine-N and deprotonated-O of the respective amino acid. …”
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OVERCOMING THE ANTINOMIES OF HUMAN EXISTENCE: ONTOLOGY OF TRICKSTER by T. V. Danylova

“…This mediator is a trickster – bipolar character (good and evil at the same time). A trickster freely acts in unordered world of Chaos without Life – Death limitations. …”
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Effect of Traditional Chinese Medicine on Inflammatory Mediators in Pediatric Asthma by Hui Du, Yonghong Wang, Yumin Shi, Jian Yu, Wen Sun, Yiqun Zhang

“…The difference of the level of IL-17 was negatively correlated with the change of C-ACT score in TCM group and SM group. Conclusion. …”
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Poldip2/Nox4 Mediates Lipopolysaccharide-Induced Oxidative Stress and Inflammation in Human Lung Epithelial Cells by Yueguo Wang, Zhenxing Ding, Youhui Tu, Xu Wu, Wenying Zhang, Shuang Ji, Jilong Shen, Li Zhang, Huimei Wu, Guanghe Fei

“…The present study demonstrated that LPS stimulation significantly increased the protein levels of Poldip2 and Nox4 and proved that Poldip2 interacted with Nox4 proved by Co-IP. Importantly, Poldip2 acted as an upstream regulator of Nox4. The increased expression of Nox4 and COX-2; NADPH enzymatic activity; production of ROS, PGE2, TNF-α, and IL-1β; and decreased HO-1 expression were significantly suppressed by lentiviral Poldip2 shRNA downregulation but were increased by lentiviral upregulation of Poldip2. …”
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Metabolic Syndrome Is Associated With Poor Prognosis in Patients With Breast Cancer Receiving Neoadjuvant Therapy by Youzhao Ma, Jingyang Zhang, Dechuang Jiao, Xiuchun Chen, Zhenzhen Liu

“…In the Cox proportional risk model, MetS acted as an independent factor associated with DFS (HR = 1.705, 95% CI: 1.201–2.421, p = 0.003) and OS (HR = 1.874, 95% CI: 1.149–3.055, p = 0.012). …”
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Pengaruh Timbal (Pb) Terhadap Kadar MDA Serum Tikus Putih Jantan by Endrinaldi ., Asterina .

“…Pb toxicityinhibitsan enzyme that acts as an antioxidant and liver cell damage.<br />The purpose of this study was to observe the effect of lead (Pb) on levels of malondialdehyde (MDA) male whiterats. …”
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Danish Digital Design and the Gradual Erosion of Technology Neutral Administrative Law by Michael Gøtze

“…Another finding of the article is that the proactive digital focus of the new regulation (acts and general administrative regulation) may come at a cost, potentially reducing the flexibility and adaptive quality of regulatory templates that are crucial to the rule of law. …”
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Optimization Study of Pneumatic–Electric Combined Braking Strategy for 30,000-ton Heavy-Haul Trains by Mingtao Zhang, Congjin Shi, Kun Wang, Pengfei Liu, Guoyun Liu, Zhiwei Wang, Weihua Zhang

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The essence and purpose of the social state in the context of the legal experience of modern Ukraine: theoretical and legal analysis by S. S. Polesov

“…The simultaneous application in relation to Ukraine of its constitutional definition as a social state and, next to it, as a democratic and legal state leads to the presence of complex relationships between these characteristics, where each of them acts as an independent manifestation of the current and prospective state existence of Ukraine, but at the same time, all these manifestations have a constitutional and legal character and reflect a certain section of the essence of this state. …”
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Wave erosion, frontal bending, and calving at Ross Ice Shelf by N. B. Sartore, T. J. W. Wagner, M. R. Siegfried, N. Pujara, L. K. Zoet

“…Stresses from foot-induced bending are likely not sufficient to initiate crevassing but rather act to propagate existing crevasses. In addition, our results support recent findings by <span class="cit" id="xref_text.1"><a href="#bib1.bibx12">Buck</a> (<a href="#bib1.bibx12">2024</a>)</span> that additional bending moments, likely due to temperature gradients in the ice, may play a role in driving frontal deflections. …”
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Antibacterial and photocatalytic activities of biosynthesized zinc oxide nanoparticle using novel plant P. macrosolen L. leaf extract by Abel Saka Gungure, Leta Tesfaye Jule, N. Nagaprasad, Krishnaraj Ramaswamy, Shanmugam Ramaswamy

“…The presence of flavonoids in P. macrosolen L. extracts was confirmed by phytochemical tests, indicating that flavonoids primarily acted as reducing agents during nanoparticle formation. …”
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