ANTIOXIDANT POTENTIAL OF TEMULAWAK (CURCUMA XANTHORRHIZA) EXTRACT GEL AS A CANDIDATE FOR WOUND HEALING by Reghita Claudia Malau, Sri Wahyuni Nasution, Ali Napiah Nasution, Wahyu Widowati, Faradhina Salfa Nindya, Hanna Sari Widya Kusuma

“…Curcuma xanthorrhiza is known to contain polyphenolic compounds, which include flavonoids acting as an antioxidant. Purpose: Examine the potential of C. xanthorrhiza extract (CXE) gel as a candidate for wound-healing by measuring its antioxidant activity. …”
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The effects of psychosocial aftercare following pediatric chronic pain treatment withstand the coronavirus disease 2019 pandemic: long-term outcomes of a randomized controlled tria... by Lisa-Marie Rau, Meltem Dogan, Gerrit Hirschfeld, Markus Blankenburg, Michael C. Frühwald, Rosemarie Ahnert, Sarah Braun, Ursula Marschall, Boris Zernikow, Julia Wager

“…Integrating PAC into routine health care to support families after IIPT should be prioritized to yield enduring treatment effects, acting as a buffer against the impacts of unpredictable adverse events.…”
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Selective suppression of influenza A/H5N1 virus replication <i>in vitro</i> using nanocomplexes consisting of siRNA and aminopropylsilanol nanoparticles by Marina N. Repkova, Asya S. Levina, Oleg Yu. Mazurkov, Elena V. Makarevich, Ekaterina I. Filippova, Natalya A. Mazurkova, Valentina F. Zarytova

“…The development of effective preparations capable of acting on target nucleic acids in cells is an urgent task. …”
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Compound identification of Shuangxinfang and its potential mechanisms in the treatment of myocardial infarction with depression: insights from LC-MS/MS and bioinformatic prediction by Yize Sun, Yize Sun, Haibin Zhao, Zheyi Wang

“…Molecular docking was modeled on AutoDock Vina software.ResultsThere were 142 bioactive compounds from PCF acting on 270 targets in a synergistic way. And a total of seven components migrating to blood were identified, including Miltionone I, Neocryptotanshinone, Danshenxinkun A, Ferulic acid, Valerophenone, Vanillic acid and Senkyunolide D. …”
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Analysis of Collective Behavior and the Psychology of the Masses. Case: October–2019, Ecuador by M. Espín, L. Vallejo, M. Gavilanez

“…The results of the investigation identified causes of the collective protests to decree 883 pronounced by the Ecuadorian government, whose effect was a series of collective behaviors, according to the psychology of the masses; these were: imitation, acting as followers, looking for affection or acceptance, frustration, repressed and controlled emotions, emotional contagion, feeling protected, defending their rights and being heard. …”
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Evolutionary and functional divergence of Sfx, a plasmid-encoded H-NS homolog, underlies the regulation of IncX plasmid conjugation by Avril Wang, Martha Cordova, William Wiley Navarre

“…Notably, we find evidence of positive selection acting on the ancestral Sfx lineage. Positively selected sites are located in the dimerization, oligomerization, and DNA-binding interfaces, many of which contribute to R6K repression activity—indicating that adaptive evolution drove the functional divergence of Sfx. …”
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Genetic Diversity, Repeat Motifs, and Natural Selection at the C-Terminal Knob-Associated Histidine Rich Protein (KAHRP) of Plasmodium falciparum Clinical Samples from Saudi Arabia by Saad M. Bin Dajem, Md Atique Ahmed, Marie Fe F Bohol, Syeda Wasfeea Wazid, Mohammed I. Shafeai, Fuad H. Rudiny, Ali M. Motaen, Kareem Morsy, Hani Alothaid, Ahmed A. Al-Qahtani

“…Thus, this study aimed to assess the allelic variations, genetic diversity, and natural selection acting at the C-terminal PfKAHRP between parasite isolates from Saudi Arabia. …”
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Exosomes Play an Important Role in the Progression of Plasma Cell Mastitis via the PI3K-Akt-mTOR Signaling Pathway by Xiaohong Wang, Yong Han, Jian Liu, Yingzhe Zhang, Kai Cheng, Jiwei Guo, Qingqun Guo, Song Liu, Hongguang Sun, Yitong Hua, Guoqiang Zhang, Shujian Xu, Fengli Guo, Zhenlin Yang

“…Our results revealed the role of exosomes acting as critical signal introduction facilitators in the progression of plasma cell mastitis and identified potential key genes in the regulation of this process. …”
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Molecular response to multiple trace element contamination of the European sardine by Beauvieux, Anaïs, Fromentin, Jean-Marc, Saraux, Claire, Romero, Diego, Couffin, Nathan, Brown, Adrien, Metral, Luisa, Bertile, Fabrice, Schull, Quentin

“…The results of this study and particularly the complex changes in protein expression demonstrate the need for future studies to test the concomitant effects of multiple stressors acting simultaneously, including large scale contamination.…”
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Genome-Wide Identification and Expression Analysis of the <i>CAMTA</i> Gene Family in Roses (<i>Rosa chinensis</i> Jacq.) by Wanyi Su, Yuzheng Deng, Xuejuan Pan, Ailing Li, Yongjie Zhu, Jitao Zhang, Siting Lu, Weibiao Liao

“…Conservative motif analysis reveals the presence of motif 1, motif 3, motif 5, motif 7, and motif 10 in all the <i>RcCAMTA</i> genes. The cis-acting element prediction results show that the rose <i>CAMTA</i> gene family contains phytohormone-signaling response elements, abiotic stress responses, light responses, and other elements, most of which are hormone-signaling response elements. …”
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Evidence for Activation of Toll-Like Receptor and Receptor for Advanced Glycation End Products in Preterm Birth by Taketoshi Noguchi, Toshiyuki Sado, Katsuhiko Naruse, Hiroshi Shigetomi, Akira Onogi, Shoji Haruta, Ryuji Kawaguchi, Akira Nagai, Yasuhito Tanase, Shozo Yoshida, Takashi Kitanaka, Hidekazu Oi, Hiroshi Kobayashi

“…The interactions between the TLR-mediated acute inflammation and RAGE-mediated chronic inflammation have clear implications for preterm birth via the TLR and RAGE system, which may be acting collectively. Conclusions. TLR and RAGE expression and their ligands, signaling, and functional activation are increased in preterm birth and may contribute to the proinflammatory state.…”
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Effect of Different Anti-hypertensive Drugs on Circadian Blood Pressure Profile in Elderly Hypertensive Patients by Bingqing YU, Jinping ZHOU, Zhongxian FENG, Junxia XU

“…According to the survey of drug use, 204 elderly hypertension patients who were treated in cadre's wards of Fuzhou General Hospital were divided into five groups: 1) long-acting calcium channel blockers (CCB group)(<italic>n</italic>=50);2) angiotensin converting enzyme inhibitors (ACEIs) or angiotensinⅡreceptor blockers (ARBs)(AA group)(<italic>n</italic>=22);3) treated with joint anti-hypertensive scheme including ACEIs or ARBs (but not including diuretics)(AAND group)(<italic>n</italic>=60);4) treated with joint anti-hypertensive scheme including diuretics (but not including ACEIs or ARBs)(DNAA group)(<italic>n</italic>=19);5) treated with joint anti-hypertensive scheme including diuretics and ACEIs or ARBs group (DAA group)(<italic>n</italic>=53), to observe the profile on circadian blood pressure in each group, binary <italic>Logistic</italic> regression analysis was used to evaluate the correlation between circadian blood pressure profile and its influencing factors.Results:Compared to the CCB group, the level of all day average SBP and daytime SBP in the DAA group were both lower (all <italic>P</italic>&lt;0.01), the decreasing level of SBP at night in the DAA group was higher (<italic>P</italic>&lt;0.05). …”
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Literature study of Zn supplementation in feed for optimizing Nile tilapia Oreochromis niloticus growth by Muhammad Agus Suprayudi, Hendri Inarto, Julie Ekasari

“… Micro minerals play a crucial role in the physiological processes of fish, acting as enzyme cofactors and stabilizing enzyme and protein structures. …”
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Cloning and Functional Analysis of <i>BraTSD2</i> Associated with Root Swelling in Turnip (<i>Brassica rapa</i> L.) by Wenyue Huang, Shifan Zhang, Fei Li, Hui Zhang, Rifei Sun, Guoliang Li, Shujiang Zhang

“…Analysis of the promoter cis-acting elements of the <i>BraTSD2</i> gene revealed that the promoter is regulated by signals associated with light response, abscisic acid, stress, salicylic acid, and MYBHI. …”
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Coupling mechanism of seepage and coal and rock mass destruction during coal and gas outburst by Shiling ZHANG, Junfei CUI, Shudong HE

“…The seepage force does not act uniformly in the coal wall, but concentrated in the thin layer less than 0.1 m near the exposed face of the coal wall. …”
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An experimental and numerical study of the ballistic behavior of an epoxy matrix hybrid composite reinforced with aramid fabric and fique fabric by Bernardo Soares Avila de Cêa, Raí Felipe Pereira Junio, Douglas Santos Silva, Fábio da Costa Garcia Filho, Sergio Neves Monteiro, Lucio Fabio Cassiano Nascimento

“…The Contact Force graph allowed observing all the interaction that occurred between the projectile and the test specimen, with the greatest acting force of 6794.7 N, until the moment in which the interaction between the bodies is considered null.…”
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Psychological and autonomous nervous system features of functional gastric dyspepsia and irritable bowel syndrome, duloxetine treatment efficacy by A. P. Pogromov, G. M. Dyukova, M. L. Leonova

“…Treatment of patients with the functional diseases by double-acting antidepressant duloxetine not only reduces psychological and autonomous nervous system disorders substantially, but also relieves main gastro-intestinal symptoms. …”
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Early selective attention to the articulating mouth as a potential female-specific marker of better language development in autism: a review by Itziar Lozano, Charlotte Viktorsson, Elena Capelli, Teodora Gliga, Valentina Riva, Przemysław Tomalski

“…If so, then sex-specific early behavioral markers, potentially acting as protective markers of language, may compensate for some genetic risk markers affecting this population. …”
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Characterization and Comparative Analysis of RWP-RK Proteins from Arachis duranensis, Arachis ipaensis, and Arachis hypogaea by Chenyang Liu, Dongliang Yuan, Tong Liu, Mengge Xing, Wenying Xu, Huiying Zhang, Hanqi Jin, Chunmei Cai, Shuai Li

“…Moreover, different numbers of cis-acting elements in the RWP-RK promoters were found in wild and cultivated species (87 in A. duranensis, 89 in A. ipaensis, and 92 in A. hypogaea), and as a result, many RWP-RK genes showed distinct expression patterns in different tissues. …”
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Predictors of biochemical and structural response to medical therapy in patients with active acromegaly following surgery: a real-world perspective by Maryam Rafieemanesh, Manizhe Ataee Kachuee, Ali Zare Mehrjardi, Alireza Khajavi, Mohammad Ghorbani, Mohammad Reza Mohajeri-Tehrani, Nahid Hashemi-Madani, Mohammad E. Khamseh

“…Methods This retrospective cohort study included 58 patients with active acromegaly following surgery treated with Octreotide long-acting release (LAR) (± Cabergoline). Biochemical outcomes were defined as the tight biochemical response (TBR; normal insulin-like growth factor-1(IGF-1)) and biochemical control (BC; IGF-1 ≤ 1.2 upper limit of normal (ULN)). …”
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