NaP-TRAP reveals the regulatory grammar in 5’UTR-mediated translation regulation during zebrafish development by Ethan C. Strayer, Srikar Krishna, Haejeong Lee, Charles Vejnar, Nils Neuenkirchen, Amit Gupta, Jean-Denis Beaudoin, Antonio J. Giraldez

“…Through this approach we identified general and developmentally dynamic cis-regulatory elements, as well as potential trans-acting proteins. We find that U-rich motifs are general enhancers, and upstream ORFs and GC-rich motifs are global repressors of translation. …”
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Challenges in reducing grand multiparity rates in Ethiopia: an analysis of 2019 EDHS data using a multilevel model approach by Diriba Dibaba, Tesfaye Getachow Charkos

“…Significant individual-level factors associated with grand multiparity include wealth index, marital status, maternal education, non-use of family planning, use of short-acting family planning, age at first birth < 18 years, and short birth intervals. …”
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Customized Random Maintenance Policies After the Expiration of a Renewal Repair–Replacement Warranty with Random Charge by Lin Zhao, Lijun Shang, Baoliang Liu

“…In the RRRW-RC, the limited mission cycles, acting as a usage limit, are used as a measurement tool to recover the fractional replacement cost within the warranty stage. …”
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Neuroprotective Effects of Metformin and Berberine in Lipopolysaccharide-Induced Sickness-Like Behaviour in Mice by Triveni Kodi, Sharanya Praveen, Sravan Kumar Paka, Runali Sankhe, Adarsh Gopinathan, Nandakumar Krishnadas, Anoop Kishore

“…Metformin, an antidiabetic agent acting via AMPK activation, possesses anti-inflammatory properties. …”
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Diversification and recurrent adaptation of the synaptonemal complex in Drosophila. by Rana Zakerzade, Ching-Ho Chang, Kamalakar Chatla, Ananya Krishnapura, Samuel P Appiah, Jacki Zhang, Robert L Unckless, Justin P Blumenstiel, Doris Bachtrog, Kevin H-C Wei

“…The synaptonemal complex (SC) is a protein-rich structure essential for meiotic recombination and faithful chromosome segregation. Acting like a zipper to paired homologous chromosomes during early prophase I, the complex is a symmetrical structure where central elements are connected on two sides by the transverse filaments to the chromatin-anchoring lateral elements. …”
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Comparative Antiviral Efficacy of Generic Sofosbuvir versus Brand Name Sofosbuvir with Ribavirin for the Treatment of Hepatitis C by L. Tang, M. Kamat, A. Shukla, M. Vora, C. Kalal, S. Kottilil, S. Shah

“…Chronic hepatitis C infection is a major cause for liver failure and liver cancer and can be treated with highly effective all oral directly acting antiviral (DAA) drugs. Generic versions of these DAAs are available in India. …”
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Discussion on the Mechanism of Gandoufumu Decoction Attenuates Liver Damage of Wilson’s Disease by Inhibiting Autophagy through the PI3K/Akt/mTOR Pathway Based on Network Pharmacol... by Lulu Tang, Chenling Zhao, Jing Zhang, Ting Dong, Huaizhen Chen, Taohua Wei, Jiuxiang Wang, Wenming Yang

“…GDFMD imparted therapeutic effects on WD through autophagy suppression by acting through the PI3K/Akt/mTOR pathway.…”
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Chemogenetic engagement of different GPCR signaling pathways segregates the orexigenic activity from the control of whole-body glucose metabolism by AGRP neurons by Valerie Espinal Abreu, Rachel Barnes, Vishnupriya Borra, Jennifer Schurdak, Diego Perez-Tilve

“…The activity of these neurons is influenced by multiple signals including those acting on G-protein coupled receptors (GPCR) activating different intracellular signaling pathways. …”
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Features of Professional Activity Reflection of the Olympiad “I Am a Professional” Participants by A. K. Belolutskaya, I. S. Krishtofik, V. A. Mkrtchyan

“…The sample included 261 students from universities in Moscow and other Russian regions, and 78 independent experts among acting school teachers. The methods of questioning (oral and written), content analysis, case studies, focus groups, video analysis, observation were used. …”
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Pan-genome analysis and expression verification of the maize ARF gene family by Quan-cai Man, Yan-qun Wang, Shun-juan Gao, Zhi-chang Gao, Zheng-ping Peng, Jiang-hui Cui

“…Simultaneously, the structural variation also influenced the conserved domain and cis-acting elements of the gene. Further combining the transcriptome data and RT-qPCR found that, The expression levels of ARF family members in maize were higher at the early stage of embryo and grain development, and the expression levels of each member in embryo and grain were complementary, and the ARF4 plays an important role in abiotic stress. …”
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Anti-constitutional activities and cover organisations of national-socialist movement in Klaipėda region in 1935-1937 by Mindaugas Valiukevičius

“…The whole movement had been de-centralised - national-socialist information distribution sources had been established in almost all legally acting organizations in Klaipėda region. Religious, youth and sports organizations were the most politically engaged and propagandistic. …”
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Like milk on the stove: Healthcare professionals navigating uncertainty when caring for families with 22q11DS. by Sophie Ayoub, Eva De Clercq, Cheryl Cytrynbaum, Luzius A Steiner, Bernice S Elger

“…After data analysis, four themes (and many sub-themes) were identified that were all related to the topic of uncertainty: acknowledging uncertainty, sharing uncertainty, acting on uncertainty and coping with uncertainty. …”
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Ground Testing of a Miniature Turbine Jet Engine for Specific Flight Conditions by Ryszard Chachurski, Łukasz Omen, Andrzej J. Panas, Piotr Zalewski

“…The test program assumed and considered the acting loads and forces in both standard and specific flight conditions, including scenarios for a heavy rain. …”
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Overweight and Obesity Coexist with Thinness among Lao’s Urban Area Adolescents by Katiya Ivanovitch, Sonemany Keolangsy, Nontiya Homkham

“…Results also indicated that, in 47.3% of the cases, teachers, acting as a source of health and nutrition information, can prevent the risk of adolescents’ overweight/obesity (aOR = 2.05, 95% CI = 1.11–3.80) but not their thinness (aOR = 0.4, 95% CI = 0.17–0.88). …”
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Functional study on the regulation of adventitious root formation by PpSAT4 gene in peach rootstock ‘GF 677’ by HAO Lanlan, WANG Hong, ZHANG Fan, ZHANG Xuebing, YANG Yang

“…Phylogenetic analysis showed that PpSAT4 had the closest relationship with European sweet cherries and almonds. Analysis of cis-acting elements showed the presence of response elements such as light, auxin, and gibberellin in the PpSAT4 sequence. (2) The overexpression vector Pp- SAT4-CAM-FLAG was constructed and transformed P . domestica and A . thaliana, and the transgenic lines were obtained. (3) qRT-PCR analysis showed that the expression level of PpSAT4 in the transgenic lines was higher than that of the wild-type. …”
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Trauma centers: an underfunded but essential asset to the community by Nasim Ahmed, Joseph L Fracasso

“…Legislations providing patients with expanded access to healthcare such as the Affordable Healthcare Act have failed to deliver on their intended purposes, and managed care organizations have moved to protect their own interest at the expense of trauma patient mortality. …”
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Observational pilot using a Data to Care intervention strategy to promote HCV re-engagement and cure for persons with HIV/HCV co-infection who are out of care by Maximilian Wegener, Deborah Gosselin, Ralph Brooks, Suzanne Speers, Merceditas Villanueva

“…Abstract Background With Direct Acting Antivirals for Hepatitis C virus (HCV), cure is possible in > 95% including those with HIV/HCV co-infection. …”
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Real-Time Resonance Detection and Active Damping in Energy Recovery Railways Applications by Giovanni Marini, Alessandro Lidozzi, Marco di Benedetto, M. Moranchel Perez, Luca Solero

“…This method estimates the dc-side resonant frequency, isolates the dc voltage oscillations around the resonant frequency, and finally attenuates the related effects by acting on the inverter current control strategy. Experimental tests are shown to validate the method using the hardware-in-the-loop real-time emulator. …”
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Social anxiety disorder and its impact in undergraduate students at Jazan University, Saudi Arabia by Ramzi M. Hakami, Mohamed S. Mahfouz, Abdulrahman M. Adawi, Adeebah J. Mahha, Alaa J. Athathi, Hadi H. Daghreeri, Hatim H. Najmi, Nuha A. Arishi

“…Students reported several clinical manifestations that affected their functioning and social life. Acting, performing or giving a talk in front of an audience was the most commonly feared situation. …”
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Multifaceted functions of the Wilms tumor 1 protein: From its expression in various malignancies to targeted therapy by Qing Nian, Yan Lin, Jinhao Zeng, Yanna Zhang, Rongxing Liu

“…Wilms tumor 1 (WT1) is a multifaceted protein with dual functions, acting both as a tumor suppressor and as a transcriptional activator of oncogenes. …”
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