Diosgenin and solasodine-based saponins and sapogenines—Effects of structural modifications on Panagrellus redivivus, Spodoptera littoralis and Trichoderma reesei by Christina Rodler, Johann Schinnerl, Miriam Schalamun, Wolfgang Hinterdobler, Lothar Brecker

“…The same reaction was applied to (22R,25R)-spirost-5-en-3β-yl α-d-3′,4′,6′-tri-O-acetyl-glucopyranoside and (22R,25R)-spirost-5-en-3β-yl β-d-2′,3′,6′-tri-O-acetyl-glucopyranosyl-(1 → 4)-β-d-8′,9′,10′,12′-tetra-O-acetyl-glucopyranoside, leading to new compounds. …”
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The role of isoniazid dosage and NAT2 gene polymorphism in the treatment of tuberculous meningitis by Yi Jian, Yuhang Bao, Fashuang Yang, Mei Zhu

“…The NAT2 genotypes were distributed as follows: 34 (28.6%) fast acetylators (FA), 73 (61.3%) intermediate acetylators (IA), and 12 (10.1%) slow acetylators (SA). …”
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Fast Hadamard-Encoded 7T Spectroscopic Imaging of Human Brain by Chan Hong Moon, Frank S. Lieberman, Hoby P. Hetherington, Jullie W. Pan

“…Linear regressions of creatine/N-acetyl aspartate and glutamate/N-acetyl aspartate with tissue gray matter content are consistent with literature values. …”
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A Novel Synthesis of 1,2,3-Benzotriazinones from 2-(o-Aminophenyl)oxazolines by Fernando Rocha-Alonzo, Daniel Chávez, Adrián Ochoa-Terán, David Morales-Morales, Enrique F. Velázquez-Contreras, Miguel Parra-Hake

“…The crystal structure of the acetyl derivative of one of the 1,2,3-benzotriazinones provided additional support for the spectroscopic structural characterization of the title compounds.…”
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Cyanuric Chloride as an Efficient Catalyst for the Synthesis of 2,3-Unsaturated O-Glycosides by Ferrier Rearrangement by Xiaojuan Yang, Na Li

“…Cyanuric chloride has been found to be an efficient catalyst for the synthesis of 2,3-unsaturated O-glycosides from the reaction of 3,4,6-tri-O-acetyl-D-glucal and a wide range of alcohols in dichloromethane at room temperature. …”
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Novel 2,3-unsaturated O-glycosides containing an alkynyl function in their aglycones by Adriana C.N. de Melo, Natália M. Bezerra, Rajendra M. Srivastava, Carlos Alberto de Simone

“…Two compounds, namely, (R)-(+)-3-butyn-2-yl 4,6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside, 3d, and (R)-(+)-3-butyn-2-yl 4,6-di-O-acetyl-2,3-dideoxy-α-D-threo-hex-2-enopyranoside, 4d, were subjected to X-ray diffraction analyses and their experimental values compared with the calculated values obtained by molecular orbital calculations. …”
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Modulation of cytokine production by carnitine by Nicola M. Kouttab, Claudio De Simone

“…The results showed that at 50 μg/ml of acetyl L-carnitine the most significant response was obtained for TNFα. …”
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A Multidisciplinary Investigation to Determine the Structure and Source of Dimeric Impurities in AMG 517 Drug Substance by Maria Victoria Silva Elipe, Zhixin Jessica Tan, Michael Ronk, Tracy Bostick

“…Further investigation revealed that these two dimeric impurities originated from existing impurities in the AMG 517 starting material, N-acetyl benzothiazole. The characterization of these two dimeric impurities allowed for better quality control of new batches of the N-acetyl benzothiazole starting material. …”
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Semisynthesis of Derivatives of Oleanolic Acid from Syzygium aromaticum and Their Antinociceptive and Anti-Inflammatory Properties by Sibusiso Rali, Opeoluwa O. Oyedeji, Olukayode O. Aremu, Adebola O. Oyedeji, Benedicta N. Nkeh-Chungag

“…In the formalin-induced pain test, the derivatives showed better analgesic effects compared to their precursor, whereas, in the tale flick test, oleanolic acid proved to be superior in analgesic effects compared to all its derivatives with the exception of the acetyl derivative. Acute inflammatory tests showed that acetyl derivatives possessed better anti-inflammatory activity compared to the other compounds. …”
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Determination of Polar Pesticides Based on a Modified QuPPe with Liquid Chromatography Coupled to Tandem Mass Spectrometry by Gözde Türköz Bakirci

“…Maleic hydrazide, glyphosate, glufosinate N-acetyl, glufosinate ammonium, fosetyl Al, ethephon, chlormequat chloride, aminomethyl phosphonic acid N-acetyl, aminomethyl phosphonic acid, cyanuric acid, ethylene thiourea, phosphonic acid, propylene thiourea, and acidified methanol solution were used to extract tomato, wheat, olive, sunflower, and herbal tea samples. …”
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Effect of Hemp Fibre Surface Treatment on the Fibre-Matrix Interface and the Influence of Cellulose, Hemicellulose, and Lignin Contents on Composite Strength Properties by Mohammad Mazedul Kabir, Mohammad Yousef Alhaik, Saud Hamad Aldajah, Kin Tak Lau, Hao Wang, Md Mainul Islam

“…The fibres were treated with alkali (0–10% NaOH), acetyl, and silane chemicals. Long unidirectional fibre composites were prepared by vacuum-assisted resin transfer moulding (VARTM) process. …”
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Acute Low-Dose Hydralazine-Induced Lupus Pneumonitis by Sarah K. Holman, Donique Parris, Sarah Meyers, Jason Ramirez

“…While the majority of HIL cases occur with high doses and prolonged treatment, cases of low-dose HIL have been reported in patients who are slow acetylators.…”
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Effects of foliar applications of γ-polyglutamic acid and alginic acid on the quality and antioxidant activity of Marselan grapes and wines by Huawei Chen, Lijian Zhang, Bowei Yang, Miaomiao Wang, Litao Ma, Jingjing Shi, Zhenwen Zhang, Qingqing Zeng

“…Among these, PGA3 treatment significantly upregulated the levels of Delphinidin-3-O-(6-acetyl)-glucoside, Cyanidin-3-O-(6-acetyl)-glucoside, Peonidin-3-O-glucoside, and Malvidin-3-O-(trans-6-O-coumaryl)-glucoside in both years. …”
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Curcumin dietary supplementation enhances serum carbohydrate-degrading enzyme activities in buffaloes by Maima Matin, Natalia Ksepka, Kamil Wysocki, Michel-Edwar Mickael, Alpana Pande, Jarosław Olav Horbańczuk, Artur Jóźwik, Olga Adamska, Artur Stolarczyk, Laszlo Barna Iantovics, Yordanka Ilieva, Pencho Penchev, Atanas G. Atanasov

“…In this work, we aimed to study the effects of curcumin supplementation in Bulgarian Murrah buffaloes (Bubalus bubalis), on the serum activities of seven important carbohydrate-metabolizing enzymes, β-glucuronidase, α-galactosidase, α-glucosidase, β-glucosidase, β-galactosidase, N-acetyl-hexosaminidase, and mannosidase. Curcumin was supplemented at a dose of 50 g per animal, per day, and serum activities of the studied enzymes were determined at the start (day 0), middle (day 14), and end (day 28) of the supplementation period. …”
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Detection and Structural Characterization of Nucleophiles Trapped Reactive Metabolites of Limonin Using Liquid Chromatography-Mass Spectrometry by Yujie Deng, Yudong Fu, Shumin Xu, Ping Wang, Nailong Yang, Chengqian Li, Qing Yu

“…Three nucleophiles, glutathione (GSH), N-acetyl cysteine (NAC), and N-acetyl lysine (NAL), were used to trap the reactive metabolites of LIM in in vitro and in vivo models. …”
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Synthesis of Novel Azetidinone and Thiazolidinones Derivatives and Evaluation of Their Antimicrobial Efficacy by K. H. Patel, A. G. Mehta

“…These anils on cyclocondensation reaction with chloro acetyl chloride and thio glycolic acid (i.e. mercapto acetic acid) yields 2-azetidinones and 4-thiazolidinones respectively. …”
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Synthesis and Antimicrobial Activity of 1-[2-(10-p-Chlorobenzyl) phenothiazinyl]-3-(substituted aryl)-2-propen-1-ones by R. K. Upadhyay, Megha S. Upadhyay, S. Jain

“…Aiming at the development of antimicrobial agents, we have synthesized nine chlorobenzyl substituted phenothiazinyl chalcones by condensing 2-acetyl phenothiazine with aldehyde derivatives in dilute ethanolic sodium hydroxide solution at room temperature according to Claisen - Schmidt condensation and subsequent reaction of products with p-chlorobenzyl bromide. …”
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One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature by Zahed Karimi-Jaberi, Korosh Mohammadi

“…β-acetamido ketones were synthesized in excellent yields through one-pot condensation reaction of aldehydes, acetophenones, acetyl chloride, and acetonitrile in the presence of boric acid as a solid heterogeneous catalyst at room temperature. …”
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Novel inhibitors of the (VIBVN) NAT protein identified through pharmacophore modeling by Wei Wei, Xionghao Li, Ning Hou, Aowei Xie, Huicong Liang, Ting Gao, Xiaoli Jing, Liqin Li, Jiejie Hao, Ximing Xu

“…These enzymes catalyze the transfer of acetyl groups from acetyl-CoA to a variety of substrates including arylamines, arylhydrazines, and N-hydroxyarylamines. …”
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High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells by Hong Feng, Junling Gu, Fang Gou, Wei Huang, Chenlin Gao, Guo Chen, Yang Long, Xueqin Zhou, Maojun Yang, Shuang Liu, Shishi Lü, Qiaoyan Luo, Yong Xu

“…This study observed the expression of NLRP3 inflammasome signaling stimulated by high glucose, lipopolysaccharide, and reactive oxygen species (ROS) inhibitor N-acetyl-L-cysteine in glomerular mesangial cells, aiming to elucidate the mechanism by which the NLRP3 inflammasome signaling pathway may contribute to diabetic nephropathy. …”
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