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1741
Membrane-bound model of the ternary complex between factor VIIa/tissue factor and factor X
Published 2025-02-01“…Using a novel computational methodology combining rigid-body protein-protein docking and extensive nonequilibrium molecular dynamics simulations in the explicit presence of a membrane, we developed, to our knowledge, the first atomic-level model of the EC, taking full account of the role of the membrane. Rigid-body docking generated 1 000 000 protein-only structures that predict the binding of key EC domains. …”
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1742
Neutrophil to Lymphocyte Ratio as a Predictor of Adverse Outcome in Patients with Decompensated Liver Cirrhosis
Published 2019-03-01“…Current clinical and laboratory prognostic models, such as Child-Pugh and MELD scales, do not take into account immune dysregulation, as well as it potential impact on the LC decompensation and the survival. …”
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1743
Fundus camera-based precision monitoring of blood vitamin A level for Wagyu cattle using deep learning
Published 2025-02-01“…More importantly, a new method was exemplified to utilise visualisation heatmap for colour-related DNNs tasks, and it was found that chromatic features extracted from LRP heatmap highlighted-ROI could account for 70% accuracy for the prediction of vitamin A deficiency. …”
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1744
A hybrid stochastic-interval Mean–CVaR model for the wind-storage system offering strategy under uncertainties
Published 2025-04-01“…Secondly, an stochastic-interval MCVaR model is developed to account for the interval uncertainty of electricity price and the risk appetite of wind-storage system operators. …”
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1745
Based on network pharmacology and molecular docking to study the mechanisms of active ingredients of ginseng in the treatment of atopic dermatitis
Published 2025-01-01“…Among the cellular components, receptor complex and membrane rafts accounted for a large proportion. KEGG enrichment analysis identified 156 signaling pathways, including IL-17, TNF and other signaling pathways. …”
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1746
Deviation from the balanced time perspective and depression and anxiety symptoms: the mediating roles of cognitive-behavioral emotion regulation in a cross-cultural model
Published 2025-02-01“…A moderated mediation model was assessed, incorporating the exogenous variable of DBTP, with ER strategies as mediators, and endogenous variables of depressive and anxiety symptoms. The model accounted for cultural variations in the paths as a moderator.ResultsSignificant associations were found between DBTP, ER strategies, depression, and anxiety symptoms. …”
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1747
On occupational safety in Ukraine in the context of social risks of preserving human capital
Published 2023-05-01“…Such decisions should take into account the provisions of the Agreement on the Ukraine-EU Association, the International Labor Organization, ratified by Ukraine, the need to develop and implement new standards for professional risks management and their integration into the general management system of the enterprise, increasing the effectiveness of state control over compliance with labor legislation, and economic incentives for employers to provide decent working conditions following the Sustainable Development Goals…”
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1748
Factors affecting the risk of gender-based violence among 2SLGBTQIA+ adolescents and youth: a scoping review of climate change-related vulnerabilities
Published 2025-02-01“…The findings revealed the necessity for multi-level strategies that account for the compounded risks faced by 2SLGBTQIA+ adolescents and youth, including those introduced by environmental crises. …”
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1749
A qualitative exploration of owner experiences following dog adoption
Published 2025-01-01“…Future research should incorporate a longer time-frame to better understand how and when dogs adjust to a home, and as there is variation in dog behaviour during adjustment, it must also account for individual differences. As we develop a better understanding of how to characterise this period, adopters can be better prepared for the initial months of dog ownership, and interventions can be individualised to improve owner experience and dog welfare.…”
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1750
Knee rotation in patients with and without patellofemoral instability and its correlation with patellar tendon trochlear groove distance
Published 2024-05-01“…However, PTTG distance appears to be a composite measure that takes into account the influence of both the patellar tendon lateralisation as well as knee rotation on patellofemoral biomechanics. …”
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1751
Refined Urban Functional Zones Identification via Empirical Bayesian Kriging: A POI-Weighted Scoring Innovation
Published 2025-01-01“…Results indicate that: 1) The EBK interpolation method not only accounts for the spatial and directional distance relationships between known and unknown sample points, but also produces more accurate raster images and provides more precise estimates in unmeasured ranges. 2) The method successfully identifies UFZs for 99.5% of the buildings in the central urban area of Xuzhou. …”
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1752
Characterization and molecular biological identification of tick species in Nanjing city
Published 2024-12-01“…Parasitic ticks were collected from goats, dogs, and hedgehogs, which accounted for 55.79% (776 ticks), 9.35% (130), and 34.87% (485) of the 1 391 parasitic ticks collected, respectively. …”
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1753
Analysis of ADR reports of cetuximab based on the FDA adverse event reporting system database
Published 2025-02-01“…The main SOCs (Skin and subcutaneous tissue disorders, investigations, metabolism and nutrition disorders, and blood and lymphatic system disorders) accounted for 58.63%. Some AEs were not on the drug label: speech disorder, intervertebral discitis, glomerulonephritis rapidly progressive and disseminated intravascular coagulation. …”
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1754
Personalized treatment strategies for breast adenoid cystic carcinoma: A machine learning approach
Published 2025-02-01“…Background: Breast adenoid cystic carcinoma (BACC) is a rare subtype of breast cancer that accounts for less than 0.1 % of all cases. This study was designed to assess the efficacy of various treatment approaches for BACC and to create the first web-based tool to facilitate personalized treatment decisions. …”
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1755
‘It takes a village’: patient lived experiences of residential treatment for an eating disorder
Published 2025-03-01“…Conclusions Participant accounts of residential treatment emphasised the importance of holistic, person-centred and recovery-oriented care. …”
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1756
EARice10: a 10 m resolution annual rice distribution map of East Asia for 2023
Published 2025-02-01“…East Asia (EA), a major global rice-producing region, accounts for approximately 29.3 % of the world's rice production. …”
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1757
A comprehensive analysis of the epidemiological and genomic characteristics of global Serratia Marcescens
Published 2025-01-01“…Human clinical samples accounted for 73.5% of the isolates, primarily from blood (44.8%) and sputum (19.3%). …”
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1758
Advancing the accuracy of tyrosinase inhibitory peptides prediction via a multiview feature fusion strategy
Published 2025-02-01“…Abstract Tyrosinase plays a crucial role as an enzyme in the production of melanin, which is the pigment accountable for determining the color of the hair, eyes, and skin. …”
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1759
Filterable PM2.5, Metallic Elements, and Organic Carbon Emissions from the Exhausts of Diesel Vehicles
Published 2020-05-01“…Measuring the carbonaceous content, we found that the total carbon (TC), the organic carbon (OC), and the elemental carbon (EC) accounted for 3461 µg m−3, 1410 µg m−3, and 2051 µg m−3 of the PM2.5 concentration, respectively. …”
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1760
Aqueous foams in microgravity, measuring bubble sizes
Published 2023-05-01“…Once various pitfalls were identified and taken into account, all the three procedures yield identical results within error bars. …”
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