Why PD-L1 expression varies between studies of lung cancer: results from a Bayesian meta-analysis by Preston Ngo, Wendy A. Cooper, Stephen Wade, Kwun M. Fong, Karen Canfell, Deme Karikios, Marianne Weber

“…We developed a statistical model to reconcile conflicting estimates of PD-L1 prevalence by accounting for between-study variation in test sensitivity, specimen age, and laboratory count. …”
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Economic Evaluation of a Novel Lung Cancer Diagnostic in a Population of Patients with a Positive Low-Dose Computed Tomography Result by Michael J. Morris, Sheila A. Habib, Maggie L. Do Valle, John E. Schneider

“…In addition, scenario analysis accounting for false negative patients from a Medicare payer perspective yielded savings of $376 902 203 per cohort and $2720 per patient. …”
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Comparison of PM2.5 Chemical Compositions during Haze and Non-haze Days in a Heavy Industrial City in North China by Menghui Li, Liping Wu, Xiangyan Zhang, Xinwu Wang, Wenyu Bai, Jing Ming, Chunmei Geng, Wen Yang

“…Additionally, an elevated TE concentration was observed during the episode (exceeding the pre- and post-haze values by 54.70% and 31.98%, respectively), with crustal elements (K, Al, Ca, Si, Na, Fe and Mg), the most abundant elemental components, accounting for 88.64%. Carbonaceous species (OC and EC) contributed 15.45% of the PM2.5 on haze days and slightly more on non-haze days. …”
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Thermal radiation and thermo-diffusion in Casson-ferrofluid over a magnetized porous surface: RSM analysis by S. Manjunatha, J. Santhosh Kumar, Khalil Ur Rehman, Wasfi Shatanawi, S.V.K. Varma

“…This study takes into account factors such as thermal radiation, heat source/sink, first-order chemical reactions, Soret, and Dufour effects. …”
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Induction of labour outcomes in a tertiary hospital: the Ghanaian cervix and misoprostol 25ug (GCAM-25 STUDY)—a cross-sectional study by Teresa Aba Mensah, Kwaku Asah-Opoku, Kwame Adu-Bonsaffoh, Evans Kofi Agbeno

“…The commonest indication for caesarean section was failure to progress, accounting for 40% of cases. The proportion of postdate women that had vaginal delivery within 24 h of induction was 117/168 (69.6%) with a CI of 62.1–76.5. …”
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Land use transition and its driving mechanisms in China’s human-elephant conflict areas by WANG Yuan, WANG Yahui, YANG Aoxi, FAN Hui, XIE Fei

“…In the core conflict areas, a multi-crop structure dominated by rubber has formed (accounting for 69.8% of the planting area). (2) Land use in the core conflict zone exhibits relatively extensive patterns, with land transfer rates and input-output efficiency demonstrating significantly lower values compared to those observed in peripheral regions. (3) Land use transition is influenced by multiple factors, including Asian elephant activities, economic development, and agricultural policy adjustments. …”
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A specific role of village doctors in reducing disparities: a quantile regression analysis of end-of-life medical care by Yuan Fang, Shih-Ting Huang, Chengrui Xiao

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Personalized medicine: An alternative for cancer treatment by Devendra Singh, Vinay Kumar Dhiman, Minakshi Pandey, Vivek Kumar Dhiman, Avinash Sharma, Himanshu Pandey, Sunil Kumar Verma, Rajeev Pandey

“…Cancer is projected to be responsible for approximately 10 million deaths in 2020, accounting for one in six deaths globally. Prostate, colon, lung, and breast cancers are the most common types of cancer. …”
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Functional Outcome by Evaluation of DASH Score on Drop Hand Patient Treated with Jones’ Tendon Transfer: A Retrospective Study by Tito Sumarwoto, Seti Aji Hadinoto, Adhitya Indra Pradhana

“…The right arm was the most frequently injured, accounting for eight patients (72.7%), while the left arm was injured in three patients (27.3%). …”
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Tuberculosis Mimicking-Musculoskeletal Tumor of The Hand: An Uncommon Case of Extrapulmonary Tuberculosis by Andy Lesmana, Hapsari Retno Dewanti, Lenty BR Perangin Angin, Muhamad Irvan Muzakky, Stefi Geovani Valentin Hayon, Mentari Maratus Sholihah, Muhammad Ifham Hanif

“…Background: Musculoskeletal extrapulmonary tuberculosis is accounting for only 10-15% of all cases. Current attention has been focused on hand tuberculosis due to its increasing prevalence. …”
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Worth the effort? A practical examination of random effects in hidden Markov models for animal telemetry data by Brett T. McClintock

“…Continuous random effect models performed reasonably well with data generated under discrete random effects, but not vice versa. Random effects accounting for unexplained individual variation can improve estimation of state transition probabilities and measurable covariate effects, but discrete random effects can be a relatively poor (and potentially misleading) approximation for continuous variation. …”
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Assessing the dynamics of  Mycobacterium bovis infection in three French badger populations by Calenge, Clément, Payne, Ariane, Réveillaud, Édouard, Richomme, Céline, Girard, Sébastien, Desvaux, Stéphanie

“…We developed a Bayesian model of prevalence accounting for the spatial structure of the cases, the imperfect and variable sensitivity of the diagnostic tests, and the correlation of the infection status of badgers in the same commune caused by local factors (e.g., social structure and proximity to infected farms). …”
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Identification of meibomian gland testosterone metabolites produced by tissue-intrinsic intracrine deactivation activity by Khanh Tien Nguyen Pham, Takahito Miyake, Tomo Suzuki, Shigeru Kinoshita, Yuki Hamada, Hikari Uehara, Mamiko Machida, Takeshi Nakajima, Emi Hasegawa, Masao Doi

“…Here, we performed radioactive tracer studies in combination with pharmacological enzyme inhibition, followed by targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis, and found three androgen metabolites—androstanedione, androsterone, and epiandrosterone—in mouse and human meibomian glands. Accounting for the enzymatic conversion, we show tissue-endogenous 3α/3β-ketosteroid reductase expression. …”
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Validation of the Food Safe Zone questionnaire for families of individuals with Prader-Willi syndrome by Elisabeth M. Dykens, Elizabeth Roof, Hailee Hunt-Hawkins, Theresa V. Strong

“…Results Principal component analyses revealed that 21 FSZ items loaded onto 5 factors that were readily interpretable, accounting for 67% of test variance: Alerting Others and Food Supervision in the Community; Locking or Restricting Food Sources; Checking for Food; At Home Supervision and Meals; and Avoiding Food Settings. …”
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Analysis of the 2016 – 2025 fiscal budget of U.S. Centers for Disease Control and Prevention by Nana LIU, Lieyu HUANG, Yuan DANG, Zekai YU, Qianqiu LIU, Yan GUO

“…From 2016 to 2025, the allocation of basic funds/project budgets mainly focused on areas such as "HIV/AIDS, Viral Hepatitis, STD, and TB Prevention," "Chronic Disease Prevention and Health Promotion," and "Immunization and Respiratory Diseases," all accounting for more than 10% of the total budget. Among them, the budget for "HIV/AIDS, Viral Hepatitis, STD, and TB Prevention" showed significant fluctuations (US$ 0.934 billion to US$ 1.553 billion), while the budget for "Immunization and Respiratory Diseases" remained at a relatively high level with minor fluctuations (US$ 0.701 billion to US$ 1.256 billion). …”
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Economic Burden of HIV in a Commercially Insured Population in the United States by Cindy Y. Chen, Prina Donga, Alicia K. Campbell, Babafemi Taiwo

“…All-cause costs PPPM for adults with PrEP were $1761 ($1938), with pharmacy costs accounting for 71%. **Conclusions:** Despite advances in ART, patients with newly diagnosed HIV and at-risk patients receiving PrEP continue to incur HRU costs. …”
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Spatiotemporal clusters of acute respiratory infections associated with socioeconomic, meteorological, and air pollution factors in South Punjab, Pakistan by Munazza Fatima, Ibtisam Butt, Shahab MohammadEbrahimi, Behzad Kiani, Oliver Gruebner

“…Results Our results indicate that in the central and northern regions of Pakistan, two spatial clusters of ARI were present, accounting for 28.5% of the total cases. A spatiotemporal cluster with a relative risk of 1.57 was discovered in the northeastern area. …”
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Pollution Characterization, Meteorological Effects, and Sources of Carbon Aerosols in PM2.5 in Urban Xiangtan during Winter by Lizhi He, Zhenghui Xiao, Cheng Xie, Yangfei Ou, Sisi Wang

“…The average winter concentrations of OC and EC were 10.75 ± 5.75 µg m–3 and 1.92 ± 0.77 µg m‒3, respectively, which accounted for 16.5% and 3.5% of the total PM2.5, respectively. …”
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Retrotrans-genomics identifies aberrant THE1B endogenous retrovirus fusion transcripts in the pathogenesis of sarcoidosis by Shunsuke Funaguma, Aritoshi Iida, Yoshihiko Saito, Jantima Tanboon, Francia Victoria De Los Reyes, Kyuto Sonehara, Yu-ichi Goto, Yukinori Okada, Shinichiro Hayashi, Ichizo Nishino

“…Abstract Transposon-like human element 1B (THE1B) originates from ancient retroviral sequences integrated into the primate genome approximately 50 million years ago, now accounting for at least 27,233 copies in the human genome, suggesting their extensive influence on human genomic architecture. …”
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