Effects of time-of-day on the noradrenaline, adrenaline, cortisol and blood lipidome response to an ice bath by Alexander Braunsperger, Maximilian Bauer, Chaima Ben Brahim, Lea Seep, Dominik Tischer, Mirko Peitzsch, Jan Hasenauer, Sieglinde Hechenbichler Figueroa, Anna Worthmann, Joerg Heeren, Kenneth A. Dyar, Karsten Koehler, Ana Soriano-Arroquia, Martin Schönfelder, Henning Wackerhage

“…Overall plasma lipid composition significantly differed in-between the morning and evening, and only in the morning ice bathing is accompanied by significantly increased plasma fatty acids from 5.1 ± 2.2% to 6.0 ± 2.4% (P = 0.029) 5 min after and to 6.3 ± 3.1% ( P = 0.008) 30 min after. …”
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IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury by Hongshuang Su, Xiaoxi Lin, Ayinuer Paredong, Ayinuer Paredong, Congcong Yao, Yan Zhang, Mengke Geng, Yuqian Guan, Lichao Gong, Feng Jiang, Qi Lv, Songtao Shou, Heng Jin

“…Inhibition of the IL-6 receptor by tocilizumab in these cells led to a reduction in cellular senescence, accompanied by decreased of the cell cycle regulatory proteins P53 and P21 in mRNA and protein levels, while alleviating cell cycle arrest. …”
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Using Human-Centered Design to Bridge Zero-Dose Vaccine Gap: A Case Study of Ilala District in Tanzania by Simon Martin Nzilibili, Hellen Maziku, Awet Araya, Ruthbetha Kateule, Millenium Anthony Malamla, Suna Salum, Furaha Kyesi, Lotalis Gadau, Tumaini Menson Haonga, Florian Tinuga, Rashid Mfaume, Zaitun Hamza, Georgina Joachim, Alice Geofrey Mwiru, Alex Benson, Oscar Kapela, Ona Machangu, Norman Jonas, Ntuli Kapologwe

“…A home-to-home interpersonal sensitization approach accompanied by the household delivery of vaccination services was employed. …”
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Neural Correlates of Balance Skill Learning in Young and Older Individuals: A Systematic Review and Meta-analysis by Lisanne B. M. Bakker, Claudine J. C. Lamoth, Tomas Vetrovsky, Markus Gruber, Simone R. Caljouw, Ward Nieboer, Wolfgang Taube, Jaap H. van Dieën, Urs Granacher, Tibor Hortobágyi

“…Conclusions Balance skill learning and the accompanying neural adaptations occur rapidly and independently of age with little to no training dose-dependence or correspondence between behavioral and neural adaptations. …”
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Derivation and validation of a clinical predictive model for longer duration diarrhea among pediatric patients in Kenya using machine learning algorithms by Billy Ogwel, Vincent H. Mzazi, Alex O. Awuor, Caleb Okonji, Raphael O. Anyango, Caren Oreso, John B. Ochieng, Stephen Munga, Dilruba Nasrin, Kirkby D. Tickell, Patricia B. Pavlinac, Karen L. Kotloff, Richard Omore

“…Model calibrations were assessed using Brier, Spiegelhalter’s z-test and its accompanying p-value. Results There was a significant difference in prevalence of LDD between the development and temporal validation cohorts (478 [32.3%] vs 69 [10.1%]; p < 0.001). …”
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HDAC and MEK inhibition synergistically suppresses HOXC6 and enhances PD-1 blockade efficacy in BRAFV600E-mutant microsatellite stable colorectal cancer by Xin Li, Peng Yang, Jin Gu, Nan Chen, Dengbo Ji, Jinhong Xia, Jinying Jia, Zhuang Sun, Mengyuan Shi, Hanyang Wang, Zhaoya Gao

“…Echoing the above findings, in vivo, HDAC and MEK inhibitors significantly improved PD-1 blockade efficacy, accompanied by increased CD8+ T-cell infiltration.Conclusions Our findings indicate that combining HDAC inhibitor, MEK inhibitor, and PD-1 blockade is a potential strategy for treating BRAFV600E-mutant MSS CRC, warranting further investigation in clinical settings.…”
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Critical depth prediction based on in-situ stress and gas content model of deep coalbed methane in Liupanshui Coalfield in China by Fang Lv, Ruidong Yang, Wei Gao, Lingyun Zhao, Yaohui Liu, Zhihua Yan, Fulun Shi, Binxin Zhang, Jingui Tang, Tongsheng Yi

“…The lateral pressure coefficient conversion depth, in-situ stress conversion depth, and gas inversion depth are delineated, accompanied by a detailed exposition of their definition process, physical significance, and interrelations. …”
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Targeted intra-tumoral hyperthermia using uniquely biocompatible gold nanorods induces strong immunogenic cell death in two immunogenically ‘cold’ tumor models by Barry E. Kennedy, Erin B. Noftall, Cheryl Dean, Alexander Roth, Kate N. Clark, Darren Rowles, Kulbir Singh, Len Pagliaro, Carman A. Giacomantonio, Carman A. Giacomantonio, Carman A. Giacomantonio

“…IL-2 post-THT induced robust CD8+ T-cell infiltration and led to sustained tumor regression in both treated and distant tumors, accompanied by the emergence of memory T cells. However, IL-2-induced immunosuppressive T-reg populations were also sustained to tumor endpoint suggesting that therapy could be further enhanced. …”
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Translation and assessment of encultured meaning of the Multi-Dimensional Scale of Perceived Social Support in Din&eacute; bizaad (Navajo) using community-based participatory actio... by Tapati Dutta, Jon Agley, Camille Keith, Gregory Zimet

“…Further, such translations have not always been accompanied by cultural adaptation. Assessment of the encultured meaning of terms from a validated instrument is important alongside translation because words and terms related to perceived social support can be culturally specific. …”
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Neuropsychiatric profile in tuberous sclerosis complex patients with epilepsy by Mahmoud Fawzi Osman, Mahmoud Fawzi Osman, Faisal Hadid, Tawfeg ben Omran, Tawfeg ben Omran, Tawfeg ben Omran, Munira Aden, Fatima Al-Maadid, Sondos Altaraqji, Khalid Mohamed, Ruba Benini, Ruba Benini

“…Epilepsy is a common neurologic feature of TSC, frequently accompanied by neuropsychiatric comorbidities. Understanding the relationship between epilepsy severity, TSC-associated neuropsychiatric disorders (TAND), and cognitive outcomes is crucial for optimizing patient care.MethodsA retrospective study was conducted at a pediatric tertiary care hospital in Qatar, involving 38 TSC patients (20 female, 18 male) aged 1–18 years, diagnosed between October 2018 and March 2020. …”
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Hubungan Indeks Massa Tubuh (IMT) dengan Usia Menarche pada Siswi SMP Negeri 1 Padang by Rahmat Nurul Yuda Putra, Ermawati Ermawati, Arni Amir

“…Several studies have found </em><em>a </em><em>decrease in age of menarche is accompanied by an increase in </em><em>Basal Metabolism Index (</em><em>BM</em><em>I).…”
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Chronic Rhinosinusitis with Nasal Polyps and Biologics: A Call for Better Data Standardisation and Presentation in Clinical Studies by Kariyawasam HH, Langan D, Rimmer J

“…However, if researchers do choose this option, then estimates should be accompanied by a standard error or confidence interval. …”
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Pola Kasus dan Penatalaksanaan Peritonitis Akut di Bangsal Bedah RSUP Dr. M. Djamil Padang by Aiwi Japanesa, Asril Zahari, Selfi Renita Rusjdi

“…Peritonitis is usually accompanied by bacteremia or sepsis </em><em>that</em><em> can cause mortality</em><em>. …”
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Mechanism of deactivation processes of excited iron(III) thiocyanato complexes with benacen-type ligands

“…Formation of polystyrene containing bonded NCS group when irradiating the complexes in the presence of styrene monomer used as a radical scavenger indicates that the primary photoreduction of Fe(III) to Fe(II) is accompanied by the oxidation of NCS<mml:math alttext="$^ - $"> <mml:mrow> <mml:msup> <mml:mi/> <mml:mo>&#x2212;</mml:mo> </mml:msup> </mml:mrow> </mml:math> ligand to <mml:math alttext="$^ ullet $"> <mml:mrow> <mml:msup> <mml:mi/> <mml:mo>&#x2022;</mml:mo> </mml:msup> </mml:mrow> </mml:math>NCS radical. 4-R-benacen-ligands behave as an innocent moiety virtually not participating in the photoinduced redox processes. …”
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Dietary supplementation with compound microecological preparations: effects on the production performance and gut microbiota of lactating female rabbits and their litters by Chengcheng Zhao, Youhao Li, Hui Wang, Ahamba Ifeanyi Solomon, Shuhui Wang, Xianggui Dong, Bing Song, Zhanjun Ren

“…ABSTRACT Early weaning is frequently accompanied by a significant increase in diarrhea and mortality rates, which reduces rabbits’ performance. …”
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Polymorphic variants of the genes for enzymes of the antioxidant system, apoptosis and inflammation as potential predictors of myocardial infarction by T. R. Nasibullin, V. V. Erdman, Y. R. Timasheva, I. A. Tuktarova, A. A. Petinseva, G. F. Korytina

“…Accordingly, the contribution of each of them separately is usually not large and may significantly depend on the state of other accompanying factors. The purpose of the study was to search for informative predictors of MI risk based on polygenic analysis of polymorphic variants of (1) the antioxidant defense enzyme genes PON1 (rs662), PON2 (rs7493), CAT (rs1001179), MSRA (rs10098474) and GSTP1 (rs1695); (2) the apoptosis genes CASP8 (rs3834129), TP53 (rs1042522) and BCL2 (rs12454712); and (3) the inflammation genes CRP (rs1205), CX3CR1 (rs3732378), IL6 (rs1800795) and CCL2 (rs1024611). 591 DNA samples were used in the study (280 patients with the onset at 30 to 60 years, with an average age of 46.02 ± 6.17, and 311 control subjects aged 30 to 62, with an average age of 44.65 ± 7.07). …”
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A novel nomogram for predicting mortality risk in young and middle-aged patients undergoing maintenance hemodialysis: a retrospective study by Lei Sun, Lei Sun, Yue Zhang, Yue Zhang, Xinliang Zuo, Xinliang Zuo, Yongmei Liu

“…ObjectivesThe annual growth in the population of maintenance hemodialysis (MHD) patients is accompanied by a trend towards younger age groups among new cases. …”
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Pengembangan Fast Render Objek Grafis Menggunakan Shader dan Non-Shader Berbasis WebGL dari Primitive Object untuk Membuat Raw Metaverse Material Objek Skybox 3D di Filkom UB by Imam Cholissodin, Eriq Muhammad Adams Jonemaro, Bayu Rahayudi, Willyan Eka Ksatria, Annisa Sukmawati, Muhammad Farid Muzayyani

“…The development problems that arise are usually related to the speedy rendering process of object engineering which in this study is making raw metaverse material in the form of adding basic 3D graphic objects (balls, cubes, torus, cylinders, and others) to the Skybox as part of augmented reality accompanied by effects of texture mapping, mirroring, coloring gradations, and animation control of object movements. …”
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State-of-the-art of loading and unloading tests for glaucoma: potentialities and informative value by O.S. Myakonkaya, A.S. Sarkisyan, A.V. Seleznev, A.V. Kuroyedov, I.R. Gazizova

“…., M-cholinomimetic or prostaglandin analog). Visual changes accompanying loading and unloading tests are recorded by visual acuity measurement, IOP measurement (tono metry and tonography, visual field testing (campimetry, angioscotometry), adaptometry, retinal tomography, and electrophysiology (visually evoked potentials). …”
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Prediction model and experimental verification of coal and gas outburst shock wave based on Shock tube theory by Xuelin YANG, Guangcai WEN, Haitao SUN, Fazhi YAN, Huiming YANG, Jie CAO, Xiaoyang CHENG, Jun LU, Huhu LI

“…The coal and gas outburst process is frequently accompanied by strong dynamic effects, and the generating outburst shock wave will cause certain casualties, even damage ventilation facilities such as air doors, thus expanding the scope of accidents. …”
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