The BET inhibitor JQ1 targets fat metabolism and counteracts obesity by Claudia Fornelli, Alessia Sofia Cento, Lorenzo Nevi, Raffaella Mastrocola, Gustavo Ferreira Alves, Giuseppina Caretti, Massimo Collino, Fabio Penna

“…Introduction: Obesity, one of the most frequent health problems in the adult population, is a condition characterized by excessive white adipose tissue accumulation and accompanied by the increased risk to develop other disorders such as type II diabetes, cardiovascular disorders, physical disability, frailty and sarcopenia. …”
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Carbon Footprint of Beef Cattle in a Conventional Production System: a Case Study of a Large-Area Farming Enterprise in the Wielkopolska Region by Jerzy Bieńkowski, Radosław Dąbrowicz, Małgorzata Holka, Janusz Jankowiak

“…The diversity of animal production systems and accompanying diversification of technological processes, mean that specific production effects can be obtained at different levels of GHG emissions. …”
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Empire Seen from Within. Cinema Objects, Spaces and Edifices in the Limelight in Colonial India and Ceylon (1899-1950) by Vilasnee Tampoe-Hautin

“…And yet, nowhere is it more relevant to include conventional cinema hardware in scientific research given that in the first instance, cinema as an art, but also an industry with a massive following, came accompanied by a vast array of optical, audio and mechanical devices. …”
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Sinomenine attenuates uremia vascular calcification by miR-143-5p by Fengyi Yu, Zhong Peng, Ning Gao, Zixu Tang, Zihao Liao, Song Zhao, Shuzhu Zhong, Gloria Umwiza, Hong Huang, Wei Long, Zhangxiu He

“…Sinomenine inhibited vascular smooth muscle cells (VSMCs) calcification, accompanied with miR-143-5p upregulation. MiR-143-5p mimic decreased VSMCs calcification in high phosphate condition. …”
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A New X-Ray and Radio Burst Activity from the Magnetar SGR 1935+2154 by Noor S. Rehan, Alaa I. Ibrahim

“…SGR 1935+2154 has emerged as the most active magnetar in recent years, exhibiting X-ray burst activity nearly annually and emitting a fast radio burst (FRB 200428 (FRB1)) in its 2020 April activity, for the first time from a Milky Way source, accompanied by an X-ray burst (X _FRB1 ). The source was active again in 2021 September and 2022 January, but without emitting radio bursts. …”
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PSYCHOLOGICAL FEATURES OF PROFESSIONAL IDENTITY CRISIS EXPERIENCE BY TEACHERS by N. O. Sadovnikova, F. Zannoni

“…However, for many teachers, the experience of a professional crisis is accompanied by a reflection of the content of professional activity, the need for reflection of own experiences and states, finding new semantic reference points, perception of own professional prospect. …”
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HUMAN DESTRUCTIVENESS IN THE EXISTING PRACTICES OF LATE MODERNISM VIOLENCE: POSITIVE AND NEGATIVE DIMENSIONS by O. V. Marchenko, L. V. Martseniuk

“…The interdependence of the violence and nonviolence practices ensures the progressive movement of humanity towards society humanization. This progress is accompanied by a natural internal conflict of personality, which can be both progressive and regressive. …”
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A study on serum potassium and serum magnesium levels in acute myocardial infarction with special emphasis on rhythm disturbance by K.I.S.N. VAISHNAVI, Vignesh C., Mariraj I., N. Krishna Geetha, Gowri Shankar A.

“…Arrhythmias, such as bradyarrhythmia or tachyarrhythmia, commonly accompany MI, contributing to its morbidity and mortality. …”
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Effect of Artemisia annua on anticoccidial action, intestinal microbiota and metabolites of Hu lambs by Shuaiqi Liu, Shiheng Li, Shuqi Cheng, Manyu Liu, Jing Li, Senyang Li, Xiaoying Li, Longxian Zhang, Fuchun Jian

“…A. annua induced significant changes in gut microbiota, accompanied by corresponding changes in metabolites. …”
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Associations of CAG repeat polymorphism in the androgen receptor gene with steroid hormone levels and anthropometrics among men: the role of the ethnic factor by L. V. Osadchuk, G. V. Vasiliev, A. V. Osadchuk

“…Positive correlations were found between the length of AR CAG repeats and estradiol levels in Buryats and testosterone levels in Yakuts, while longer CAG repeats were accompanied by higher estradiol levels in Buryats and testosterone levels in Slavs and Yakuts. …”
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The effect of soaking heat-polymerized acrylic resin denture base in avocado seed extract (Persea americana Mill.) on the inhibition of denture-plaque microorganisms biofilm growth... by Siti Wahyuni, Thalia Angela, Susanna Halim

“…The research data were analyzed using a univariant test, and a one-way ANOVA test, accompanied by Welch ANOVA on non-homogenous data. Results In this research, it was found that the MBIC50 of avocado seed extract against the mono-species of C. albicans (5%), C. glabrata (5%), A. odontolyticus (15%), S. gordonii (15%), S. aureus (10%), while against polymicrobial was 20%. …”
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Month-to-Month Variability of Autumn Sea Ice in the Barents and Kara Seas and Its Relationship to Winter Air Temperature in China by Chuhan Lu, Kaili Li, Shaoqing Xie, Zhaomin Wang, Yujing Qin

“…The retreat of autumn Arctic sea ice is typically accompanied by negative anomalous winter temperatures over the Eurasian and North American continents. …”
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Entropy generation and heat convection analysis of second-grade viscoelastic nanofluid flow in a tilted lid-driven square enclosure: A finite difference approach by Anil Ahlawat, Mukesh Kumar Sharma, K. Loganathan

“…Moreover, with Eckert number (Ec) average Nusselt number diminishes, accompanied by an increase in both Ns and Beavg. Heat convection and entropy production are enhanced with forward inclination of the square enclosure and is slightly diminished with backward inclination.…”
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Sneak Peek: Food, Waste, and Packaging Characteristics of South Australian School Children’s Lunchboxes by Neha Kishan Lalchandani, Clare Hume, Lynne Giles, Shona Crabb, Jo Hendrikx, Caroline Miller

“…Conclusions: Sandwiches, fruits, and various snacks are typical lunchbox foods, often accompanied by single-use packaging. Considering both health and environmental factors in lunchbox choices could benefit children and sustainability efforts in schools. …”
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The usage of personalized scheme of fentanyl administration during coronary artery stenting by D.О. Dziuba

“…The usage of a personalized scheme of fentanyl administration for stenting of the coronary arteries, compared to the standard sedation using combination of diazepam and fentanyl, was accompanied by better indicators of intraoperative blood saturation with oxygen and carbon dioxide (respectively (103.67 ± 22.05) and (39.64 ± 6.85) mm Hg in group 1, (105.70 ± 31.64) and (37.68 ± 7.11) in group 2 and (109.42 ± 34.36) and (36.25 ± 6.52) mm Hg in patients of the 3rd group), lower blood pressure after surgery ((127.85 ± 9.87)/(79.64 ± 8.62) mm Hg in patients of group 1, (129.48 ± 8.73)/(81.05 ± 7.92) mm Hg in group 2 and (131.15 ± 10.64)/(82.68 ± 9.72) mm Hg in group 3), lower level of stress markers (blood cortisol during surgery in patients of the 1st group (8.83 ± 4.58) mmol/L, in patients of the 2nd group – (7.73 ± 2.79) mmol/L, in patients of the 3rd group – (7.55 ± 4.35) mmol/L), as well as lower frequency of detecting episodes of perioperative pain of various origins. …”
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Specificity of psychological readiness for changes and personality’s maturity of the employees of the state criminal and executive service by O. V. Mitroshkina

“…In both groups, the growth of personality maturity is accompanied by a facilitation of psychological readiness for changes. …”
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Professional Self-Determination and Professional Identity of Students-Teachers in the Conditions of Individualisation of Education by E. G. Belyakova, I. G. Zakharova

“…The model, previously designed by the authors to accompany professional self-determination of teachers-students, is clarified. …”
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Remote symptom monitoring with patient-reported outcomes and nudges during lung cancer immunotherapy in China (PRO-NET): protocol for a randomised controlled trial by Ping He, Yanan Luo, Zhenyu Shi, Yiqi Xia, Xiaolong Guan

“…For advanced NSCLC, immunotherapy offers substantial survival benefits but is often accompanied by severe immune-related adverse events symptoms, significantly affecting health-related quality of life (HRQoL). …”
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IL-13 Augments Histone Demethylase JMJD2B/KDM4B Expression Levels, Activity, and Nuclear Translocation in Airway Fibroblasts in Asthma by Khuloud Bajbouj, Mahmood Y. Hachim, Rakhee K. Ramakrishnan, Huwaida Fazel, Jumana Mustafa, Shahed Alzaghari, Mahmoud Eladl, Jasmin Shafarin, Ronald Olivenstein, Qutayba Hamid

“…Furthermore, IL-13 stimulation induced JMJD2B expression and further demethylation of H3K36me3 in asthmatic fibroblasts. This was accompanied by increased translocation of JMJD2B into the nucleus. …”
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Regulation of innate immune response by miRNAs up-regulated in Stevens-Johnson syndrome with severe ocular complications by Mayumi Ueta, Hiromi Nishigaki, Hokoru Yoshioka, Shigeru Kinoshita, Chie Sotozono

“…Abstract Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe mucocutaneous disorders characterized by extensive tissue necrosis; they are often accompanied by severe ocular complications (SOC). The regulatory role of microRNAs (miRNAs) in modulating immune responses in SJS/TEN is not fully understood, particularly in relation to chronic SOC. …”
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