Psychosocial distress, perceived need and utilization of psycho- social support services in patients in the early phase after the first cancer diagnosis by Hannah Zingler, Diana Steinmann, Jochen Ernst, Ute Goerling, Myriel Hermann, Beate Hornemann, Anja Mehnert-Theuerkauf, Tanja Zimmermann

“…Abstract Purpose Due to the growing number of new oncological diagnosis and the accompanying psychosocial burden, needs-based psycho-oncological care is important. …”
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The Role of Microelements of Lumbar Disc Degeneration in Patients Undergoing Lumbar Spine Surgery by Sadiq R. Karkush, Manal K. Rasheed, Ali T. Abdul Wahid, Ahmed R. Majeed

“…In addition to the discomfort of lower back pain, it can accompany pain in one or both legs. The lumbar spine and sacrum, consisting of five vertebrae and one bone, determine the spine's balance. …”
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Distribution, Risk Assessment, and Quantitative Source Analysis of Soil Heavy Metals in a Typical Agricultural City of East-Central China by Wenyue Du, Peng Zeng, Shi Yu, Fan Liu, Ping’an Sun

“…The land use in agricultural areas contributes to economic growth while concurrently accompanied by a series of environmental pollution issues. …”
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Laparoscopic suture repair for perforated peptic ulcer disease: a meta-review and trial sequential analysis by S. I. Panin, T. V. Nechay, I. V. Sazhin, K. Yu. Melnikov-Makarchuk, A. V. Sazhin, A. V. Puzikova, A. N. Akinchits, A. V. Bykov

“…Further trials with regard to mortality, surgical site infection, and intra-abdominal abscess are not very promising because the DARIS did not exceed 5% after combining the results of eight RCTs.ConclusionSummarization of evidence from systematic reviews and reanalysis using TSA confirmed sufficient evidence for only one outcome, namely, that laparoscopic suture repair of PPUs is accompanied by lower pain scores at 24–72 h. Regarding the issues of postoperative complications and mortality, achieving DARIS through additional studies seems unpromising.…”
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Automated process assessment of primary healthcare for hyperlipidemia: preliminary findings and implications form Anhui, China by Ningjing Yang, Yuning Wang, Ying Li, Dongying Xiao, Ruirui Cui, Nana Li, Rong Liu, Jing Chai, Xingrong Shen, Debin Wang

“…Results The study revealed interesting findings including: low and varied rates of visits for HL(from 0.01 to 1.43%) and visits by patients with EDHL/CNHL(from 0.13 to 20.54% or from 0.02 to 2.99%) between regions; large differences (5.14 to 22.20 times) between the mean or cumulative proportions of visits by patients with EDHL versus CNHL among clinician groups; consistent increase in the ratio of visits for HL in all cause visits over the study period (from 0.087 to 1.000%) accompanied with relatively stable proportions of patients with CNHL/EDHL; Relatively low scores in the procedure-based measures (ranged from 0.00 to 36.08% for specific procedures by seasons). …”
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Don’t move a mussel: The role of key environmental drivers and management scale in assessing spatial variation in dreissenid spread risk in the Missouri River basin by Joseph Raymond, Lucas S. Bair, Timothy D. Counihan, Wesley M. Daniel, Sofie Duntugan, Matthew E. Neilson, Michael Springborn

“…Another contribution is that the CRR index includes user-specified weights for certain parameters so that a user can adjust the relative importance of various factors to match their specific context. An accompanying web tool allows users to view the CRR results and adjust multiple parameters to see the resulting impacts on the CCR for watersheds in the Missouri River Basin.…”
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Political Crisis in France: «Gilets Jaunes» and the End of the «First Period» of the Emmanuel Macron’s Governance by E. O. Obichkina

“…The current crisis is partly a consequence of the protracted identity crisis at both extremes of French political spectrum, resulting from a long period of relatively conflict-free alternation of left and center-right parties in a relatively favorable economic environment that accompanies the development of a consumer society and a social state. …”
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PEDAGOGICAL CONTENT THREE-FACTOR MODEL OF EDUCATING HIGH-SCHOOL STUDENTS FOR PROFESSIONAL ACTIVITIES by T. A. Lopatukhina, A. V. Rynkevich

“…Their cooperation envisages the following stages: first, teacher’s strict guidance of a student; then – teacher’s soft support of a student; after this – teacher’s accompanying a student at a special request and, at last, – wise consulting a student if needed. …”
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Achievements and prospects of applying high-throughput sequencing techniques to potato genetics and breeding by I. V. Bykova, N. A. Shmakov, D. A. Afonnikov, A. V. Kochetov, E. K. Khlestkina

“…This review gives analysis of databases containing potato genome and transcriptome sequencing results, as well as accompanying resources. This information should prove useful while planning comparative assays of potato transcriptome or application of DNA-markers. …”
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Study on Mechanical Performance of Prestressed UHPFRC U-Beam Bridges by Mengying Liu, Eugen Brühwiler, Fengkun Cui, Yue Xu

“…The bending failure of a U-shaped beam belongs to the group of ductile failures, which is characterized by the main crack along the central rib and the loading center, which is accompanied by multiple microcracks. The failure process can be divided into four stages: linear deformation, microcracks development, main cracks development, and bearing capacity decline. …”
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Immunogenicity of recombinant fragment of orthopoxvirus p35 protein in mice by Ya. A. Khlusevich, A. L. Matveev, E. P. Goncharova, I. K. Baykov, N. V. Tikunova

“…However, providing a high level of protection, the vaccination is often accompanied by serious post-vaccination complications, the probability of which is particularly great for individuals with compromised immunity. …”
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Efficient recovery of rare metal lanthanum from water by MOF-modified biochar: DFT calculation and dynamic adsorption by Qilan Huang, Qianru Zhang, Shuwen Zhao, Chuchen Zhang, Huixin Guan, Jianqiao Liu

“…MIL-88b@BC interacted better with La3+ than biochar or MOF did. Accompanying batch tests with the theoretical conjecture's verification demonstrated that the pseudo-second-order model and the Langmuir model, respectively, provided a good fit for the adsorption kinetics and isotherms. …”
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Association between adolescent obesity and early adulthood healthcare utilization—a two-cohort prospective study by Emilia Hagman, Vidar Halsteinli, Resthie R. Putri, Christina Hansen Edwards, Gudrun Waaler Bjørnelv, Claude Marcus, Rønnaug A. Ødegård

“…Results A total of 7592 individuals from Norway (5.7% with adolescent obesity) and 1543 individuals from Sweden with adolescent obesity, accompanied with 7330 matched general population comparators, were included. …”
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Inhibition of RAC1 activator DOCK2 ameliorates cholestatic liver injury via regulating macrophage polarisation and hepatic stellate cell activation by Jianli Qiu, Yitong Qu, Yinli Li, Cancan Li, Junling Wang, Lu Meng, Xiaojin Jing, Jiangping Fu, Yan Xu, Yuna Chai

“…In vitro experiments further demonstrated that DOCK2 knockdown suppressed M1 macrophage polarisation and HSC to myofibroblast transition, accompanied by inhibition of RAC1 activation. Conclusions In summary, this study demonstrates for the first time that the RAC1 activator DOCK2 regulates M1 macrophage polarisation and hepatic stellate cell activation to promote cholestasis-induced liver inflammation and fibrosis, suggesting that DOCK2 may be a potential therapeutic target in cholestatic liver injury.…”
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Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings... by Hassan Haghparast-Bidgoli, Michelle Heys, Caroline Crehan, Erin Kesler, Monica Lakhanpaul, Emma Wilson, Fabiana Lorencatto, Felicity Fitzgerald, Mario Cortina Borja, Msandeni Chiume, Hannah Gannon, Simbarashe Chimhuya, Gwendoline Chimhini, Tim Hull-Bailey, Tarisai Chiyaka, Yali Sassoon, Deliwe Nkhoma, Nushrat Khan, Alexander G. Stevenson, Kristina Curtis

“…Since 2014, we have worked in Bangladesh, Malawi, Zimbabwe and the UK to develop and pilot Neotree: an android app with accompanying data visualisation, linkage and export. …”
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Circulating MicroRNAs in Patients with Psoriasis Treated with Anti-IL-23: A Cohort Study by Federico Diotallevi, Giulia Matacchione, Anna Campanati, Elena Marinelli Busilacchi, Nadia Viola, Ilaria Pace, Beatrice Fontana, Roberta Roncarati, Massimiliano Bonafè, Manuela Ferracin, Jacopo Sabbatinelli, Fabiola Olivieri

“…Results Significant clinical improvement was observed in all patients after 1 year of treatment, accompanied by increased Treg counts and reduced levels of pro-inflammatory cytokines. …”
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Clinical features of cystic neutrophil granulomatous mastitis in 62 cases by Mengjie Wang, Dongxiao Zhang, Na Fu, Min Liu, Hongkai Zhang, Shuo Feng, Yifei Zeng, Wenjie Zhao, Jianchun Cui, Khattak Mazher Mansoor

“…The primary clinical manifestations were characterized by pain and palpable masses, accompanied by redness, ulceration, nipple discharge, and nipple retraction. …”
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Chloroquine and Rapamycin Augment Interleukin-37 Expression via the LC3, ERK, and AP-1 Axis in the Presence of Lipopolysaccharides by Xiaoyi Shi, Chunhui Lai, Lianyu Zhao, Mingying Zhang, Xi Liu, Shanqin Peng, Weizhong Guo, Qiuying Xu, Song Chen, Guang-xing Chen

“…Inductive IL-37 expression was accompanied with increased phosphorylated Erk1/2 and AP-1 and could be completely abolished by an Erk1/2 inhibitor or augmented by Erk1/2 agonists. …”
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Structured lactation support for mothers of very low birthweight preterm infants and establishment of human donor milk banks in German NICUs (Neo-MILK): protocol for a hybrid type... by Angela Kribs, Nicole Ernstmann, Nadine Scholten, Martin Hellmich, Antje Hammer, Eva Mildenberger, Andreas Müller, Dirk Horenkamp-Sonntag, Juliane Köberlein-Neu, Tim Ohnhäuser, Katja Matthias, Jens Ulrich Rüffer, Nicola Gabriela Dymek, Julia Jaschke, Anna Katharina Stirner, Isabella Schwab, Daniel Wiesen, Till Dresbach, Friederike Eyssel, Katharina Lugani, Anne Sunder-Plaßmann, Melanie Klein, Christoph Rupprecht

“…A process evaluation and an economic analysis will accompany the study. The data set comprises survey and interview data and routinely collected data from medical records. …”
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Therapeutic effects of cyclophosphamide, dsDNA preparations and combinations thereof against Krebs-2 ascites cancer cells and various cancer transplants by E. A. Potter, E. V. Dolgova, A. M. Minkevich, Ya. R. Efremov, O. S. Taranov, V. V. Omigov, V. P. Nikolin, N. A. Popova, A. S. Proskurina, E. I. Vereschagin, A. V. Kozel, V. A. Rogachev, D. B. Petrov, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, S. S. Bogachev

“…When Krebs-2 ascites are treated with human DNA 1-12 hours post CP injection, this results in either elimination of cells that internalize TAMRA-labeled DNA (TISCs) or alters their phenotype, which is accompanied with the loss of surface expression of CD34. …”
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