Radiation decreases bronchial epithelial progenitor function as assessed by organoid formation by Merian E. Kuipers, Dennis K. Ninaber, Krista C.J. van Doorn-Wink, Annelies M. Slats, Pieter S. Hiemstra

“…Despite an effect on organoid formation capacity, DNA breaks, P21/CDKN1A expression and reduced expression of MKI67 and E2F1, this effect was not accompanied by IR-induced cytotoxicity, or an increase in markers of inflammation or EMT. …”
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A methodology to compile multi-hazard interrelationships in a data-scarce setting: an application to the Kathmandu Valley, Nepal by H. E. Thompson, J. C. Gill, R. Šakić Trogrlić, F. E. Taylor, B. D. Malamud

“…These exemplars are collated into a Kathmandu Valley Single Hazards and Multi-Hazard Interrelationships Database (Thompson et al., 2024) accompanying this paper. We supplement these exemplars with multi-hazard interrelationship scenarios and multi-hazard impacts developed by practitioner stakeholders engaged in DRR research and practice in the Kathmandu Valley. …”
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Infusion of Autologous Retrodifferentiated Stem Cells into Patients with Beta-Thalassemia by Ilham Saleh Abuljadayel, Tasnim Ahsan, Huma Quereshi, Shakil Rizvi, Tamseela Ahmed, Sabiha Mirza Khan, Jawaid Akhtar, Ghazi Dhoot

“…Over 6 months, Infusion of 3-h autologous RSC subjected to hematopoietic-conducive conditions into patients with beta-thalassemia reduced mean blood transfusion requirement, increased mean fetal hemoglobin synthesis, and significantly lowered mean serum ferritin. This was always accompanied by an increase in mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) in such patients. …”
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Attitudes of polish medical students toward organ donation by Marzena Mikla, Anna Maria Cybulska, Antonio Rios, Mariusz Panczyk, Kamila Rachubińska, Artur Kotwas, Beata Karakiewicz, Elżbieta Grochans, Daria Schneider-Matyka

“…The reluctance to donate the organs of loved ones for transplantation is accompanied by a lack of a sense of moral obligation and a lack of solidarity with those in need. …”
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TERT de novo mutation-associated dyskeratosis congenita and porto-sinusoidal vascular disease: a case report by Ge Yu, Guijie Xin, Xu Liu, Wanyu Li, Chen Shao, Runping Gao

“…Case presentation A 16-year-old Han male patient experienced unexplained black stool for 7 days, accompanied by dizziness and fatigue. On examination, there were mesh pigmentations on the exposed areas of the skin on both hands and feet. …”
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CircBAZ1B stimulates myocardial ischemia/reperfusion injury (MI/RI) by modulating miR-1252-5p/ATF3-mediated ferroptosis by Ruili Wei, Tianxiao Yang, Weihong Li, Xiqian Wang

“…Results The results showed that MI/RI was accompanied by ferroptosis. We also found that activating transcription factor 3 (ATF3) knockdown promoted myocardial cell viability and inhibited ferroptosis. …”
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Study on influencing factors of age-adjusted Charlson comorbidity index in patients with Alzheimer's disease based on machine learning model by Jian Ding, Jian Ding, Zheng Long, Yiming Liu, Min Wang

“…BackgroundAlzheimer's disease (AD) is a widespread neurodegenerative disease, often accompanied by multiple comorbidities, significantly increasing the risk of death for patients. …”
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The regulatory effects of (p)ppGpp and indole on cAMP synthesis in <i>Escherichia coli</i> cells by N. M. Kashevarova, E. A. Khaova, A. G. Tkachenko

“…When tryptophan was added to the medium, both of these strains demonstrated high indole production, which was accompanied by a decrease in cAMP accumulation compared to the tryptophan-free control. …”
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Metronidazole-Induced Pancreatitis: Is There Underrecognition? A Case Report and Systematic Review of the Literature by Ibrahim Youssef, Naba Saeed, Mohammad El Abdallah, Kara Huevelhorst, Kais Zakharia

“…The most common presenting symptom and sign was moderate to severe epigastric pain and tenderness, accompanied by nausea/vomiting. Symptoms usually start within 2-7 days of starting the medication and usually resolve 2-5 days after discontinuation of therapy and pancreatitis treatment. …”
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Association between fasting blood glucose and psychotic symptoms in Chinese patients with first-episode drug-naïve major depressive disorder by Xingzhi Xia, Hanxu Deng, Wei Ren, Lin Yang, Yingzhao Zhu, Yaozhi Liu, Junjun Liu, Xueli Zhao, Fengnan Jia, Xiangdong Du, Xiangyang Zhang

“…Abstract Introduction Psychotic depression (PD) is a highly debilitating disorder characterized by hallucinations and/or delusions accompanied by depression. A variety of neurotransmitters, hormones and corresponding receptors in the endocrine system are involved in the onset and progression of depression, and fasting blood glucose (FBG) can be an important indicator for monitoring the stability of the endocrine system. …”
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Non-Alcoholic Fatty Liver Disease in Cardiac Patients with Overweight and Obesity by I. V. Logacheva, T. A. Ryazanova, V. R. Makarova, O. V. Surnina

“…The results of the study have revealeda connection between the NAFLD presence and the main markers of visceral fat depots (IAT, EAT, VAI), which is shown to increase the risk of cardio-vascular complications in such patients. NAFLD is accompanied by endothelial dysfunction and a change in the most significant parameters of cardiac and vascular remodelling. …”
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Psychosocial, physical, cognitive and quality of life aspects in primary restless legs syndrome by I. Jarašiūnaitė, R. Kaladytė-Lokominienė

“…RLS has a significant impact on the quality of life. The syndrome is accompanied by nocturnal sleep disturbances and excessive daytime sleepiness. …”
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Case-area targeted interventions and free chlorine residual in household drinking water: An observational cohort study during a cholera outbreak in Northeast Nigeria. by Lindsay Salem-Bango, Jennifer OKeeffe, Michael R Desjardins, Daniele Lantagne, Chiara Altare, Gurpreet Kaur, Kanaganathan Rangaiya, Patricia Oke-Oghene Obroh, Ahmadu Audu, Chimda Emmanuel Solomon, Thomas Heath, Emmanuel Emeka Ihemezue, Solomon Aye, Baptiste Lecuyot, Mustafa Sikder, Shannon Doocy, Melody Xiao, Paul B Spiegel

“…During CATI response in Borno, Adamawa, and Yobe, research enumerators accompanied CATI teams to households and observed interventions (including provision of soap, Aquatabs, educational materials, and jerrycans; latrine and bedding disinfection; and hygiene promotion) and collected data on demographics, existing household water, sanitation, and hygiene, and household water free chlorine residual (FCR). …”
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Diversity of high-molecular-weight glutenin subunits and evaluation of genetic similarities in spring bread wheats from different breeding centers by M. U. Utebayev, N. A. Bome, E. C. Zemtsova, O. O. Kradetskaya, I. V. Chilimova

“…A single change in the Glu-1 subunit composition, 2*, 7+9 and 2+12, caused a reduction in grain quality (= 7 score); and the combination of Null, 7 and 5+10 was accompanied by the lowest (= 6) grain quality. The analysis showed that two loci, Glu-A1 and Glu-B1, induced significant differences between wheat accessions originated from Tyumen and Chelyabinsk, while the accessions from Chelyabinsk and East Kazakhstan differed significantly at the Glu-A1 and Glu-D1 loci.…”
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Sistem Deteksi Dini Penyakit Preeklampsia Melalui Perubahan Warna Urine Berdasarkan Protein dengan Menggunakan Metode Naïve Bayes Classifier by Fakhrul Allaam, Barlian Henryranu Prasetio, Rizal Maulana

“…This disease occurs due to high blood pressure, without edema or swelling and accompanied by protein in the urine (proteinuria). This condition can usually occur in the 2nd and 3rd trimester of pregnancy or later 20 weeks. …”
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Acid-Base Balance in Healthy Adults: Beneficial Effects of Bicarbonate and Sodium-Rich Mineral Water in a Randomized Controlled Trial: The BicarboWater Study by Katharina Mansouri, Theresa Greupner, Edda van de Flierdt, Inga Schneider, Andreas Hahn

“…HBS water consumption led to increased urinary pH (24-hour urine and spontaneous urine, both p<0.001) and bicarbonate levels (p<0.001), accompanied by reduced titratable acids (p<0.001) and ammonium (p<0.001), resulting in a lower renal net acid excretion (p<0.001). …”
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Astrocyte-Derived Interleukin 11 Modulates Astrocyte–Microglia Crosstalk via Nuclear Factor-κB Signaling Pathway in Sepsis-Associated Encephalopathy by Dandan Zhu, Peng Wang, Xiyue Chen, Kaituo Wang, Yunsong Wu, Min Zhang, Jianhua Qin

“…Upon LPS exposure for astrocytes, we detected that more microglia migrated to the central astrocyte culture compartment on the microfluidic device, accompanied by M1 polarization and increased cell motility in microglia. …”
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An Analysis of Land Use Conflicts and Strategies in the Harbin–Changchun Urban Agglomeration Based on the Production–Ecological–Living Space Theory and Patch-Generating Land Use Si... by Xiaomeng Wang, Yanjun Zhang, Xiaoyan Li, Shuwen Cao

“…The results indicate the following: (1) From 2000 to 2020 and different scenarios in 2030, the PELS of the HCUA is dominated by forest ecological space (E1) and agricultural production space (P1), with no substantial alterations in the overall spatial distribution of the PELS. (2) Absolute and relative conflicts between 2000 and 2020 are mainly concentrated in the plains of the western regions, characterized by conflicts arising from the encroachment of living space on production space; however, absolute conflicts have declined annually, accompanied by a notable enhancement in ecological quality. (3) The spatial pattern of absolute conflicts in 2030 exhibits minimal variation, illustrating higher values in the western regions compared to the eastern parts, with living space surpassing ecological space and plains showing higher conflict values than mountains. …”
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Medial Open-Wedge High Tibial Osteotomy with Partial Meniscectomy and Without Cyst Excision for Popliteal Cysts: A Case Series by Kang-Il Kim, Jun-Ho Kim

“…<b>Introduction:</b> Popliteal cysts (PCs) are occasionally accompanied by knee osteoarthritis (OA) and varus malalignment. …”
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Health utility value of overactive bladder in Japanese older adults by Takashi Yoshioka, Kenji Omae, Satoshi Funada, Tetsuji Minami, Rei Goto

“…Abstract Objectives To determine the health utility values (HUVs) of overactive bladder (OAB), defined as urinary urgency, usually accompanied by urinary daytime or nocturnal frequency, with or without urinary incontinence, among adults aged ≥65 years and to assess the HUV decrements (disutilities) of OAB according to its severity. …”
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