Crowned dens syndrome: A case series of 72 patients at eight teaching hospitals in Japan by Hiroki Isono, Haruka Kuno, Takunori Hozumi, Ken Emoto, Sho Nishiguchi, Masahiro Sakai, Madoka Ito, Koichi Kitamura, Kazuhito Hirose, Eiji Hiraoka, Naoto Ishimaru, Hiroyuki Kobayashi, Yasuharu Tokuda

“…Abstract Background Crowned dens syndrome (CDS) is characterized by calcification around the odontoid process, accompanied by neck pain. Although CDS is supposedly rare, we regularly diagnose and manage this condition, indicating a perception gap between previous studies and our experience. …”
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Matched Unrelated Donor Hematopoietic Cell Transplantation: Increased Usage and Improvements in Clinical Outcomes in Canada by Matthew D. Seftel, Grace Musto, David Allan, Oliver Bucher, Kevin Hay, Ivan Pasic, Tony Truong, Kristjan Paulson

“…Improvements in OS after MUD HCT were accompanied by corresponding reductions in the 2-year non-relapse mortality after MUD HCT. …”
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Human PBMC-based humanized mice exhibit myositis features and serve as a drug evaluation model by Akiko Nishidate, Kana Takemoto, Yuki Imura, Mikako Murase, Ryu Yamanaka, Manami Kikuchi, Junpei Anan, Sayuka Kato, Airi Akatsuka, Sachiko Mochizuki, Yuzo Koda

“…Abstract Idiopathic inflammatory myopathies (IIMs) are a group of autoimmune disorders characterized by immune cell infiltration of muscle tissue accompanied by inflammation. Treatment of IIMs is challenging, with few effective therapeutic options due to the lack of appropriate models that successfully recapitulate the features of IIMs observed in humans. …”
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Metal‐Mediated Chlorine Transfer for Molten Salt‐Driven Thermodynamic Change on Silicon Production by Minjun Je, Jin Chul Kim, Jiyeon Kim, Sungho Kim, Sunmin Ryu, Jaegeon Ryu, Sang Kyu Kwak, Soojin Park

“…., Mg) establishes additional energetic shortcuts in reaction pathways, where AlCl3 directly detaches an oxygen atom, accompanied by strong metal‐oxygen interactions and Cl* transfer within the same complex. …”
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Characterizing a complex buildup in the Pearl River Mouth Basin of the northern South China Sea: an interplay of carbonates and igneous rocks by Beichen Chen, Leyi Xu, Baojun Liu, Lili Zhang, Dong Xiao, Ya Gao, Ya Gao, Feng Wu, Xueqi Yang, Yaming Zou, Yongkun Ma, Yinglin Zhang

“…The evolution of the buildup is divided into three stages: (1) volcanic eruptions and carbonates development, (2) overflowing magma and reef shoal deposits, and (3) reef-bank deposition accompanied by igneous intrusion. We propose that volcanic rocks can be distinguished from carbonates by the temporal and spatial coupling of typical features: (a) surface volcanic rocks and subsurface intrusive bodies are inseparable, with igneous rocks identifiable through faults and volcanic conduits; (b) carbonates typically display symmetrical structures on both sides of the highland and exhibit better stratification away from igneous activity; (c) carbonates generally show a convex clinoform and steep slope at the platform margin, while volcanic mounds exhibit concave gentle slopes. …”
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Mendelian randomization analysis of the causal relationship between trimethylamine N-oxide and its precursors and Parkinson’s disease by Bei Zhang, Ruijie Zhang, Huiming Ren, Qiongfeng Guan, Weinv Fan, Liyuan Han

“…These SNPs were employed as instrumental variables in a random-effects model to evaluate the causal relationship between circulating concentrations of TMAO and its precursors and the risk of Parkinson’s disease, by estimating odds ratios with accompanying 95% confidence intervals. The primary analysis employed the inverse variance-weighted (IVW) method, which was complemented with MR-Egger regression analysis. …”
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Hidden cause of paralysis: tight filum terminale in spinal cord injury without radiographic abnormality by Yi Yuan, Yi Yuan, Zong Jian An, Fei Gao, Zhi Hui Li, Wei Li Xu, Yong Sun

“…For children with SCIWORA accompanied by tethered cord syndrome, we recommend early surgical intervention to perform laminectomy and release the tethered cord, which may aid in the recovery of neurological function.…”
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Evaporation-Induced Water and Solute Coupled Transport in Saline Loess Columns in Closed and Open Systems by Jian Xu, Wei Lan, Yanfeng Li, Wen-Chieh Cheng, Jun Yuan, Qinghai Tan

“…As the evaporation proceeded, a relatively stable water profile was reached as the intensity of water supply approached to that of evaporation, accompanied by a continual migration of solutes towards the surface. …”
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ENDOPROSTHESIS OF THE SHOULDER JOINT IN METASTATIC LESIONS OF THE PROXIMAL HUMERUS DURING IMMUNOSUPPRESSIVE THERAPY by M. V. Ivanova, V. Yu. Karpenko, A. V. Bukharov, V. A. Derzhavin

“…It must be emphasized that in the context of immunosuppression bacterial infection is much greater and is accompanied by greater mortality than in patients without immunosuppression. …”
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Echocardiographic Features of Cardiomyopathy in Emery-Dreifuss Muscular Dystrophy by Michał Marchel, Agnieszka Madej-Pilarczyk, Agata Tymińska, Roman Steckiewicz, Janusz Kochanowski, Julia Wysińska, Ewa Ostrowska, Paweł Balsam, Marcin Grabowski, Grzegorz Opolski

“…Emery-Dreifuss muscular dystrophy (EDMD) is a very rare type of muscular dystrophy characterized by musculoskeletal abnormalities accompanied by cardiac defects. Two most common genetic subtypes are EDMD1 due to EMD and EDMD2 caused by LMNA gene mutations. …”
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Functional connectivity in burnout syndrome: a resting-state EEG study by Natalia Afek, Dmytro Harmatiuk, Magda Gawłowska, João Miguel Alves Ferreira, Krystyna Golonka, Sergii Tukaiev, Sergii Tukaiev, Anton Popov, Anton Popov, Tadeusz Marek

“…This study presents an analysis of brain functional connectivity in a resting state, thus providing a deeper understanding of the mechanisms accompanying burnout syndrome. The sample consists of 49 burnout employees and 49 controls, matched by age, gender and occupation (Mage = 36.15, SD = 8.10; 59 women, 39 men). …”
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Do wolframin, P-glycoprotein, and GRP78/BiP cooperate to alter the response of L1210 cells to endoplasmic reticulum stress or drug sensitivity? by Simona Kurekova, Lucia Pavlikova, Mario Seres, Viera Bohacova, Jana Spaldova, Albert Breier, Zdena Sulova

“…However, this protein is frequently overexpressed in cells undergoing ERS and its expression may accompany changes in the above ERS markers. Therefore, our aim in this work was to investigate wolframin expression in P-gp-negative and P-gp-positive murine leukemia L1210 cells in relation to ERS related proteins in normal or ERS condition. …”
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Investigating Two-dimensional Horizontal Mesh Grid Effects on the Eulerian Atmospheric Transport Model Using Artificial Neural Network by Amine Ajdour, Brahim Ydir, Houria Bouzghiba, Ishaq Dimeji Sulaymon, Anas Adnane, Dris Ben Hmamou, Kenza Khomsi, Jamal Chaoufi, Gábor Géczi, Radouane Leghrib

“…The second aspect demonstrates: (4) CHIMERE-Artificial Neural Network (CHIMERE-ANN) demonstrates high accuracy in predicting ozone levels for Agadir and Casablanca, achieving improved correlation coefficients of 80% and 94%, respectively, accompanied by a notable decrease in Root Mean Square Error (RMSE) to 7.5 µg m–3 and 7.4 µg m–3. (5) Implementing CHIMERE-ANN with high spatial resolution concentrations (RA3 and RC3) enhances the accuracy of pollutant concentration forecasts. …”
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High-dose thiamine supplementation ameliorates obesity induced by a high-fat and high-fructose diet in mice by reshaping gut microbiota by Yu Xia, Yu Xia, Lulu Wang, Yanyan Qiu, Weihong Ge, Weihong Ge, Weihong Ge

“…Furthermore, oral administration of high-dose thiamine also regulated HFFD-induced gut microbiota dysbiosis by reshaping its structure and composition of gut microbiota, such as increasing the relative abundance of Actinobacteria and Bifidobacterium pseudolongum, and reducing the relative abundance of Proteobacteria and Ruminococcus gnavus, accompanied by decreased level of gut-derived endotoxin. …”
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Neurotoxic Effect of Myricitrin in Copper-Induced Oxidative Stress Is Mediated by Increased Intracellular Ca²⁺ Levels and ROS/p53/p38 Axis by Ignacija Vlašić, Antonio Krstačić-Galić, Anđela Horvat, Nada Oršolić, Anja Sadžak, Lucija Mandić, Suzana Šegota, Maja Jazvinšćak Jembrek

“…The myricitrin-induced decrease in survival was accompanied with increased reactive oxygen species (ROS) production, reduced superoxide dismutase activity, and a lower GSH/GSSG ratio. …”
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Analgesic Appraisal of Bidens pilosa (Asteraceae) Leaf Extracts Used in Management of Oral Lesion Pain in HIV/AIDS Patients in Rodents by Joseph Obiezu, Chukwujekwu Ezeonwumelu, Muhammad, Ntale, Steve, Okwudili Ogbonnia, Ezera, Agwu, Julius, Kihdze Tanayen, Ahmed, Adebowale Adedeji, Okonkwo, Chukwudi Onyeka, Ambrose, Amamchukwu Akunne, Jennifer, Chibuogwu Ebosie, Frederick, Byarugaba

“…HIV/AIDS infection complications include tissue damage from oral lesions accompanied with pains. Pain is a disagreeable sensory and sensitive experience associated with actual or potential tissue damage. …”
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Gonadal health benefits of black cumin (Nigella sativa) seed oil on chronic lead-exposed male Wistar rats by Afrina Mustari, Mahabub Alam, Samia Rashid, A.G.M.Sofi Uddin Mahamud, Mohammad Alam Miah, Emdadul Hauqe Chowdhury

“…Moreover, Pb exposure led to a notable reduction in sperm motility, sperm concentration, testis weight, and testis diameter, accompanied by seminiferous tubule degeneration. However, the administration of NSO effectively counteracted the adverse effects induced by chronic Pb exposure in rats. …”
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Influences of Infrared Dye Content and Laser Energy Density on Laser Propulsion Performance of ADN-Based Liquid Propellants by Lizhi Wu, Jinle Cao, Jingyuan Zhang, Jingwei Zeng, Yue Pan

“…Significantly luminous plasma appears in the ablation plume at higher laser energy densities, accompanied by higher-velocity plasma shock waves. Compared to the factor of the infrared dye content, the laser energy density contributes more to the ablation efficiency, especially when the increase in laser energy density promotes the full release of chemical energy from the liquid propellant, which, in turn, also enhances the impulse, impulse coupling coefficient, and the plasma detonation velocity. …”
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Quantitative Approach for Determining Reproductive Life‐History Strategies of Parasitic Plants: A Case Study in Balanophora by Trevor Padgett, Huei‐Jiun Su, Shu‐Hui Wu, Li‐yen Huang, Yiching Lin

“…No primary study investigated the question, and no determination was accompanied by reference. Between 2021 and 2024, we tested a hypothesis of perenniality (109 individuals, 135 patches) and cryptic perenniality (73 host samples), monitored population dynamics (whole population), and potential for endophytic/dormant haustorial tissue (101 roots) across five isolated populations of Balanophora fungosa ssp. fungosa in Taiwan. …”
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Battling time restrictions with collective discourse: collaborative quizzes in a condensed human anatomy course by Zi Guo, Natascha Heise

“…The exponential growth of medical knowledge, accompanied by societal changes and expectations for the upcoming generation of physicians, is placing immense pressure on academic institutions to reform their curricula, particularly foundational courses such as human anatomy. …”
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