Integrating genetics and transcriptomics to characterize shared mechanisms in digestive diseases and psychiatric disorders by Huanxin Ding, Yue Jiang, Qing Sun, Yingchao Song, Shuohui Dong, Qian Xu, Linzehao Li, Chuxuan Liu, Bingjun Li, Hengxuan Jiang, Bichen Peng, Shi Peng, Chumeng Zhang, Jiankang Zhu, Mingwei Zhong, Guangyong Zhang, Xiao Chang

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Characteristics and Influencing Factors of Soil CH4 and N2O Fluxes in Typical Broad-leaved Forests in the Yangtze River Delta Region, China by JIA Qinqi, XU Fei, CHEN Bingjiang, LU Yanran, CHEN Lihan, HU Jiahao, GUO Na, FANG Shuangxi

“…[Methods] Taking the typical broad-leaved forest soil in Hangzhou, Zhejiang Province as the research object, soil-air interface CH4 and N2O fluxes were continuously measured from November 2022 to November 2023 by the static chamber-gas chromatography method. …”
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Exploring Self-Management Behavior Profiles in Patients with Multimorbidity: A Sequential, Explanatory Mixed-Methods Study by Fu Y, Wu J, Guo Z, Shi Y, Zhao B, Yu J, Chen D, Wu Q, Xue E, Du H, Zhang H, Shao J

“…In the quantitative phase (August 2022 to May 2023), data were collected from 1,920 multimorbid patients across nine healthcare facilities in Zhejiang Province. Latent Profile Analysis (LPA) was used to identify distinct self-management behavior profiles. …”
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Oncolytic peptide LTX-315 induces anti-pancreatic cancer immunity by targeting the ATP11B-PD-L1 axis by Meng Wang, Xing Huang, Tingbo Liang, Tianyu Tang, Gang Zhang, Minghao Lu, Zhengtao Hong, Junming Huang, Xiao Zhi

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Gestational weight gain and adverse pregnancy outcomes: a prospective cohort study by Jun Zhang, Yuelin Wu, Sheng Wan, Shengyi Gu, Zhengqian Mou, Lingling Dong, Zhongcheng Luo, Xiaolin Hua

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Multi-Class Guided GAN for Remote-Sensing Image Synthesis Based on Semantic Labels by Zhenye Niu, Yuxia Li, Yushu Gong, Bowei Zhang, Yuan He, Jinglin Zhang, Mengyu Tian, Lei He

“…To evaluate the quality of image generation, we tested multiple models on two custom datasets (one from Chongzhou, Sichuan Province, and another from Wuzhen, Zhejiang Province, China) and a public dataset LoveDA. …”
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Role of metabolic characteristics in the co-occurrence of insomnia, Alzheimer’s disease, and Parkinson’s disease: a Mendelian randomization study by Chengyong Liu, Chi Wang, Jing Jiang, Yuyang Bo, Lixiu Nan, Ying Zhang, Kongxi Zhu, Xiaoqiu Wang, Xinxin Feng, Xiaoyang Lian, Shan Qin

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Enhanced Control Efficacy of Different Insecticides Mixed with Mineral Oil Against Asian Citrus Psyllid, <i>Diaphorina citri</i> Kuwayama, Under Varying Climates by Wei Hu, Kejing Wang, Xiaoyue Zhong, Pei Jiang, Shunchang Zhang, Zhanjun Lu, Zhixiang Zhang, Long Yi, Ning Zhang

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Functionality of bacterial communities in constructed wetlands used for water purification: influence of root components and seasonality by Yao Huang, Yao Huang, Weili An, Weili An, Tianzhu Ning, Zhiguang Ma, Yuelin Li, Ke Liu, Lingbo Ji, Lingbo Ji, Hongxiao Liu, Dafeng Hui, Hai Ren

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Cardiac resynchronization therapy via left bundle branch pacing in heart failure with complete left bundle branch block: is the defibrillator needed? by Dandan Yang, Dandan Yang, Qunchao Ma, Qunchao Ma, Hong Zhu, Lihua Wang, Meixiang Xiang, Meixiang Xiang, Jian’an Wang, Jian’an Wang, Jian’an Wang, Jian’an Wang, Xiaohong Pan, Xiaohong Pan

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The Clinical Characteristics, Patterns of Recurrence, and Long-Term Survival Outcomes of Dual-Phenotype Hepatocellular Carcinoma After Curative Liver Resection by Yu ZC, Fang ZK, Yu Y, Liu SY, Wang KD, Shi ZJ, Jin LM, Huang XK, Lu Y, Shen GL, Liu JW, Huang DS, Zhang CW, Liang L

“…Zi-Chen Yu,1,2 Zheng-Kang Fang,1,2 Yang Yu,3 Si-Yu Liu,4 Kai-Di Wang,1,5 Zhe-Jin Shi,1,5 Li-Ming Jin,1 Xiao-Kun Huang,1,2 Yi Lu,1 Guo-Liang Shen,1 Jun-Wei Liu,1 Dong-Sheng Huang,1 Cheng-Wu Zhang,1 Lei Liang1 1Department of Hepatobiliary & Pancreatic Surgery and Minimally Invasive Surgery, General Surgery, Cancer Center, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Postgraduate Training Base Alliance of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Urology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China; 4Department of Laboratory Medicine, The Key Laboratory of Imaging Diagnosis and Minimally Invasive Interventional Research of Zhejiang Province, Zhejiang University Lishui Hospital, Lishui, Zhejiang, People’s Republic of China; 5Department of the second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of ChinaCorrespondence: Lei Liang, General Surgery, Cancer Center, Department of Hepatobiliary and Pancreatic Surgery and Minimal Invasive Surgery, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, 310014, People’s Republic of China, Email liangl1992@hotmail.comBackground & Aims: Dual-phenotype hepatocellular carcinoma (DPHCC) is discernible from classical HCC (CHCC) in its morphology and is characterized by the co-expression of both CHCC and cholangiocyte markers. …”
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Key considerations based on pharmacokinetic/pharmacodynamic in the design of antibody-drug conjugates by Yangyang Gao, Yuwei Xia, Yixin Chen, Shiqi Zhou, Yingying Fang, Jieru Yu, Leyin Zhang, Leyin Zhang, Leitao Sun, Leitao Sun, Leitao Sun

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Clinical Characteristics of Asymptomatic Patients with SARS-CoV-2 in Zhejiang: An Imperceptible Source of Infection by Wei Dai, Xinmiao Chen, Xiaoting Xu, Zhefeng Leng, Wenwen Yu, Hui Lin, Huiying Li, Jie Lin, Zhangwei Qiu, Yuanrong Dai

“…In this study, epidemiological investigations were conducted in the Zhejiang province to understand the epidemiology and clinical characteristics of asymptomatic patients with COVID-19. …”
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Innovative CO2-NBs-assisted ultrasonication for the phytochemical extraction of peanut (Arachis hypoga) shells: Synthesis and characterization of CO2-nanobubbles by Nayyar Iqbal, Miral Javed, Ramy M. Khoder, Areej Areej, Renyu Zheng, Shanbai Xiong, Ibrahim Khalifa, Hassan Barakat, Youming Liu

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Effects of Ciprofol and Propofol General Anesthesia on Postoperative Recovery Quality in Patients Undergoing Ureteroscopy: A Randomized, Controlled, Double-Blind Clinical Trial by Shi S, Wu J, Wu Y, Han X, Dai H, Chen X, Sun Z, Wang F

“…Shuqi Shi,1,2,&ast; Jimin Wu,1,&ast; Yini Wu,1 Xin Han,1 Hong Dai,1 Xuedong Chen,3 Zhangnan Sun,4 Faxing Wang1,2 1Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 2Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Urology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 4Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Faxing Wang, Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, No. 15, Dazhong Street, Lishui, Zhejiang Province, 323000, People’s Republic of China, Email wfx2023@wmu.edu.cn Zhangnan Sun, Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People’s Republic of China, Email 28703077@hebmu.edu.cnObjective: This study compares postoperative recovery quality between Ciprofol and Propofol, providing a reference for the clinical application of anesthetics.Methods: We randomized 112 patients undergoing ureteroscopic surgery into two groups: the Ciprofol group (Group C), with an induction dose of 0.4 mg/kg and a maintenance dose of 0.8– 1.5 mg/(kg·h), and the Propofol group (Group P), with an induction dose of 2 mg/kg and a maintenance dose of 4– 10 mg/(kg·h). …”
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Disturbed shear stress promotes atherosclerosis through TRIM21‐regulated MAPK6 degradation and consequent endothelial inflammation by Feng Wang, Shu‐Yu Wang, Yue Gu, Shuai Luo, Ai‐Qun Chen, Chao‐Hua Kong, Wen‐Ying Zhou, Li‐Guo Wang, Zhi‐Mei Wang, Guang‐Feng Zuo, Xiao‐Fei Gao, Jun‐Jie Zhang, Shao‐Liang Chen

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Whether Detection of Gene Mutations Could Identify Low- or High-Risk Papillary Thyroid Microcarcinoma? Data from 393 Cases Using the Next-Generation Sequencing by Lei Jin, Liang Zhou, Jian-Biao Wang, Li Tao, Xiao-Xiao Lu, Na Yan, Qian-Ming Chen, Li-Ping Cao, Lei Xie

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NSUN2 lactylation drives cancer cell resistance to ferroptosis through enhancing GCLC-dependent glutathione synthesis by Kaifeng Niu, Zixiang Chen, Mengge Li, Guannan Ma, Yuchun Deng, Ji Zhang, Di Wei, Jiaqi Wang, Yongliang Zhao

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Intervening Non-Small-Cell Lung Cancer Progression by Cell Membrane Coated Platycodin D via Regulating Hsa-miR-1246/FUT9/GSK3&beta; Pathway by Zheng S, Xie Z, Zhou Z, Wang S, Xin Y, Lin J, Cheng K, Lu T, Qi R, Guo Y

“…Shuyu Zheng,1,2 Zejuan Xie,1 Ziao Zhou,1 Shanshan Wang,1 Yanlin Xin,1 Jiamin Lin,1 Keyu Cheng,1 Tianming Lu,1 Ruogu Qi,1 Yuanyuan Guo1 1Department of Biochemistry and Molecular Biology, School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, People’s Republic of China; 2Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang Province, 310009, People’s Republic of ChinaCorrespondence: Ruogu Qi; Yuanyuan Guo, Department of Biochemistry and Molecular Biology, School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, People’s Republic of China, Email rqi@njucm.edu.cn; guoyy@njucm.edu.cnPurpose: Metastatic non-small cell lung cancer (NSCLC) remains a global health threat, with patients facing inevitable disease progression despite standard-of-care therapy. …”
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A cohort study of serum 25-hydroxyvitamin D levels and the risk of hyperlipidaemia in adults by Zi-yue Liu, Sha Liu, Xue Yao, Chun-yang Wang, Yunhao Song, Yan-ming Bi, Jin-Xiu Wang, Yang Li, Ta-la Shi, Wei Mi, Caiyun Chen, Zhi-Yong Hu

“…ObjectiveThis study aims to investigate the potential association between serum 25(OH)D levels and the risk of hyperlipidemia in adults through a prospective cohort study conducted in Zhejiang Province.MethodsBaseline surveys and follow-up studies were conducted to collect and analyze follow-up data over a three-year period. …”
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