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161
Exploring the distribution and fate of bisphenol A in an aquatic microcosm combined with a multimedia model
Published 2025-01-01“…In this study, a four-compartment system [water, sediment, biota (zebrafish), and submerged aquatic vegetation (Vallisneria natans)] of a point source continuous discharge microcosm was established to investigate the distribution and fate of BPA in an aquatic microcosm. …”
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162
Preservation of Aquatic Environmental DNA Using Cationic Detergents
Published 2024-11-01“…In this study, we assessed the effect of short‐ and long‐term water storage using three different cationic surfactants on the half‐life of zebrafish (Danio rerio) mitochondrial DNA (mtDNA) in mesocosm water. …”
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163
Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry for Identification of In Vitro and In Vivo Metabolites of Bornyl Gallate in Rats
Published 2013-01-01“…Previous studies have strongly suggested that BG is worthy of further investigation due to antioxidant, antiatherosclerosis activities, and obvious activity of stimulating intersegmental vessel growth in zebrafish. This work was designed to elucidate the metabolic profile of BG through analyzing its metabolites in vitro and in vivo by a chromatographic separation coupled with a mass spectrometry. …”
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164
miR-126 and miR-126*: New Players in Cancer
Published 2010-01-01“…Knock-out studies in zebrafish and mice suggested a major role of miR-126 in angiogenesis and vascular integrity, which was mediated by the repression of inhibitors of VEGF-induced proliferation in endothelial cells. …”
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165
Molecular Modulation of Fetal Liver Hematopoietic Stem Cell Mobilization into Fetal Bone Marrow in Mice
Published 2020-01-01“…We discussed the molecular regulations of fetal HSC expansion in mouse and zebrafish. It is also unknown how HSCs from the fetal liver mobilize, circulate, and reside into the fetal bone marrow niche. …”
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166
Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson’s Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo
Published 2020-01-01“…We also verified the effect of suramin in the zebrafish PD model. Treatment with suramin could significantly reverse 6-OHDA-induced locomotor deficits and improved tyrosine hydroxylase (TH) via attenuating endoplasmic reticulum (ER) stress biomarkers. …”
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167
Natural Pigments from Gardenia jasminoides J. Ellis and Peristrophe bivalvis (L.) Merr for Food Coloring
Published 2024-01-01“…In addition, toxicity tests on zebrafish embryos indicated that these extracts had low toxic activities with high LD50 values of 1.31 g/L for Gardenia extract and 0.74 g/L for Peristrophe extract. …”
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168
Unveiling the toxicity of JWH-018 and JWH-019: Insights from behavioral and molecular studies in vivo and vitro
Published 2025-01-01“…JWH-018 induced time- and dose-dependent cannabinoid-like effects in mice (administration dosages: 0.02, 0.1, and 0.5 mg/kg, i.p.), and yielded dose-dependent anxiogenic effects and lower aggression behavior in zebrafish (administration dosages: 0.01, 0.05, and 0.25 µg/g, i.p.), unlike JWH-019. …”
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169
<i>Aspergillus oryzae</i> Fermented <i>Plumula Nelumbinis</i> Against Atopic Dermatitis Through AKT/mTOR and Jun Pathways
Published 2024-12-01“…Moreover, FPN can also alleviate SDS-induced inflammation in zebrafish. It is also found that the anti-inflammatory activity of <i>Plumula Nelumbinis</i> was enhanced by <i>Aspergillus oryzae</i> fermentation, and the oil phase of the fermentation product showed better activity, which may be due to microbial fermentation changing the structure of the original alkaloids. …”
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170
Thymosin β4 Improves Differentiation and Vascularization of EHTs
Published 2017-01-01“…Furthermore, we demonstrated, in a zebrafish model of embryonic vascular development, that Tβ4 is crucial for the proper execution of lymphatic and angiogenic vessel sprouting. …”
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171
Hematopoietic stem cell discovery: unveiling the historical and future perspective of colony-forming units assay
Published 2025-01-01“…In this review, we explore the fundamental discoveries concerning the CFUs assay by covering the following aspects: (i) the historical overview of the CFUs assay for the study of clonal hematopoiesis involving multilineage potential of HSPCs, (ii) its use in various experimental models comprising humans, mice/rodents, zebrafish and induced pluripotent stem cells (iPSCs) and (iii) research gaps and future direction concerning the role of CFUs assay in clinical and basic sciences. …”
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172
AcfA Regulates the Virulence and Cell Envelope Stress Response of <i>Vibrio parahaemolyticus</i>
Published 2024-12-01“…The deletion of <i>acfA</i> had no effect on bacterial growth but resulted in a significant reduction in biofilm formation, hemolytic activity, mucus adhesion, and the accumulated mortality of zebrafish, compared to the wild-type strain and the complementary strain <i>acfA</i><sup>+</sup>. …”
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173
Creating burdock polysaccharide-oleanolic acid-ursolic acid nanoparticles to deliver enhanced anti-inflammatory effects: fabrication, structural characterization and property evalu...
Published 2023-03-01“…Compared with ALPs, ALP-OA/UA nanoparticles showed enhanced anti-inflammatory activity (especially at a dose of 100 μg/mL) in a CuSO4-induced zebrafish inflammation model via down-regulating the NF-κB signalling pathway and gene expression of associated transcription factors and cytokines (TNF-α, IL-1β and IL-8). …”
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174
Characterization of polyethylene and polyurethane microplastics and their adsorption behavior on Cu2+ and Fe3+ in environmental matrices
Published 2025-02-01“…The zeta-potential measurements as a function of pH provided insights into the dispersion behavior of microplastics (MPs) in freshwaters, suitable for the growth of Zebrafish (Egg water) and Daphnia magna (Elendt M7 Water). …”
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175
Gelatin/PLA-loaded gold nanocomposites synthesis using Syzygium cumini fruit extract and their antioxidant, antibacterial, anti-inflammatory, antidiabetic and anti-Alzheimer’s acti...
Published 2025-01-01“…The anti-Alzheimer activity was confirmed by inhibition of the AChE (76.37 ± 1.18%) and BChE (85.94 ± 1.38%) enzymes. In vivo studies of zebrafish embryos showed that Ge/PLA/AuNCs have excellent biocompatibility and nontoxicity. …”
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176
MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology
Published 2025-02-01“…We also studied the functional expression of the MCU complex in Drosophila, Zebrafish, and Caenorhabditis elegans. These analyses provide a basis for exploring potential treatment strategies targeting the MCU complex and provide strong support for the development of future precision medicine and treatments. …”
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177
Ru(II) Complexes Bearing O, O-Chelated Ligands Induced Apoptosis in A549 Cells through the Mitochondrial Apoptotic Pathway
Published 2020-01-01“…Notably, complex Ru-1 showed low toxicity to developing zebrafish embryos. The obtained results suggest that these new synthetic complexes have the potential to be developed as low-toxicity agents for lung cancer treatment.…”
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178
Rapid method for identification of transgenic fish zygosity
Published 2007-07-01“…In this experiment, we applied a quantitative real-time PCR (qr-PCR) method to analyze zygosity in a stable line of transgenic zebrafish (Danio rerio) carrying masu salmon, Oncorhynchus masou D6-desaturase-like gene. …”
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179
A rare deleterious missense mutation in the AXIN2 gene in Chinese women with polycystic ovary syndrome
Published 2025-12-01“…The evolutionary conservation analysis of the identified Axin-2 mutant was analyzed among 15 vertebrates from human to zebrafish. The protein structure change was analyzed between the wild-type and mutation-type. …”
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180
Modulation of DAPK1 expression by its alternative splice variant DAPK1-215 in cancer
Published 2025-01-01“…Cell migration, invasion, and proliferation assays were conducted in vitro, and a zebrafish model was employed to evaluate metastatic potential. …”
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