Emotional stress increases GluA2 expression and potentiates fear memory via adenylyl cyclase 5 by Qian Yang, Ahmad Abdulla, Muhammad Farooq, Yoshihiro Ishikawa, Siqiong June Liu

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A potential VEGF-driven hypothesis of calvarial centripetal proliferation in cerebral proliferative angiopathy by Shigeta Miyake, Timo Krings, Tze Phei Kee, Thierry A. G. M. Huisman

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Is a quantifier mismatch a problem for L1 Japanese learners of English? by Paul N. Nehls, Kodai Aramaki, Tomohiro Fujii

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Tadalafil treatment for fetuses with early-onset growth restriction: a protocol for a multicentre, randomised, placebo-controlled, double-blind phase II trial (TADAFER IIb) by Hiroaki Tanaka, Yasuhiro Tanaka, Yoichi Aoki, Masayuki Endo, Tomoaki Ikeda, Shintaro Maki, Masafumi Nii, Kayo Tanaka, Satoshi Tamaru, Toru Ogura, Yuki Nishimura, Tomomi Kotani, Akihiko Sekizawa, Masahiko Nakata, Koji Nakamura, Kenji Nagao, Ichiro Yasuhi, Hiroshi Kawamura, Sho Takakura, Mayumi Kotera, Takafumi Ushida, Norihiko Kikuchi, Tadatsugu Kinjo, Mayumi Takano, Sachie Suga, Michi Kasai, Osamu Yasui, Yuka Maegawa, Shigeru Aoki, Yoshio Yoshida

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Characteristics and clinical significance of immune cells in omental milky spots of patients with gastric cancer by Yasunobu Mano, Yasunobu Mano, Yuka Igarashi, Yuka Igarashi, Keisuke Komori, Keisuke Komori, Itaru Hashimoto, Itaru Hashimoto, Hayato Watanabe, Kosuke Takahashi, Kazuki Kano, Hirohito Fujikawa, Takanobu Yamada, Hidetomo Himuro, Hidetomo Himuro, Taku Kouro, Taku Kouro, Feifei Wei, Feifei Wei, Kayoko Tsuji, Kayoko Tsuji, Shun Horaguchi, Shun Horaguchi, Shun Horaguchi, Mitsuru Komahashi, Mitsuru Komahashi, Mitsuru Komahashi, Takashi Oshima, Tetsuro Sasada, Tetsuro Sasada

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Adult Nephroblastoma with Predominant Epithelial Component: A Differential Diagnostic Candidate of Papillary Renal Cell Carcinoma and Metanephric Adenoma—Report of Three Cases by Shiho Watanabe, Hiroshi Naganuma, Michio Shimizu, Satoshi Ota, Shin-ichi Murata, Naoki Nihei, Jun Matsushima, Shuji Mikami, Naoto Kuroda, Yoji Nagashima, Yukio Nakatani

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Impact of the First Wave of COVID-19 on the Number of General Anesthesia Cases in 34 Tertiary Hospitals in Japan: A Multicenter Retrospective Study by Tomonori Takazawa, Yuki Sugiyama, Yasuhiro Amano, Tetsuhito Hara, Eiki Kanemaru, Takao Kato, Takashi Kawano, Tsukasa Kochiyama, Tatsuya Tsuji, Shigeru Saito

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Examining sufficiency and equity in the geographic distribution of physicians in Japan: a longitudinal study by Yuichi Imanaka, Susumu Kunisawa, Koji Hara, Tetsuya Otsubo

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Factors associated with ABCDEF bundle implementation for critically ill patients: An international cross-sectional survey in 54 countries by Junpei Haruna, Takeshi Unoki, Keibun Liu, Kensuke Nakamura, Shigeaki Inoue, Osamu Nishida

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A mouse model of deep vein thrombosis by inferior vena cava hypoperfusion using ameroid constrictors by Hiroko Tadokoro, Yukihide Ota, Mari Uomoto, Shiro Koizume, Shinya Sato, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Yoko Endo-Takahashi, Yoichi Negishi, Etsuko Miyagi, Yohei Miyagi

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Development of the membrane ceiling method for in vitro spermatogenesis by Maki Kamoshita, Hiroki Shirai, Hiroko Nakamura, Tetsuya Kishimoto, Yuki Hatanaka, Daisuke Mashiko, Katsuhiro Esashika, Jingjing Yang, Satoshi Yamasaki, Takehiko Ogawa, Hiroshi Kimura, Masahito Ikawa

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Corneal Topographic Changes Due to Pediatric Epiblepharon Surgery by Shindo J, Matsumura N, Nakamura J, Asano M, Ohno T, Mizuki N

“…Jun Shindo,1,2 Nozomi Matsumura,1 Jutaro Nakamura,2 Mizuki Asano,1 Tomoko Ohno,1 Nobuhisa Mizuki2 1Department of Ophthalmology, Kanagawa Children’s Medical Center, Yokohama, Kanagawa, 232-8555, Japan; 2Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, 236-0004, JapanCorrespondence: Jun Shindo, Department of Ophthalmology, Kanagawa Children’s Medical Center, Mutsukawa, Yokohama, Kanagawa, 232-8555, Japan, Tel +81 45 711 2351, Fax +81 45 721 3324, Email junjunon.nike.6228@gmail.comPurpose: This study aimed to investigate changes in corneal morphology following pediatric lower-lid epiblepharon surgery using a topographic modeling system 5 (TMS-5®).Patients and Methods: A randomized controlled trial compared two surgical interventions for pediatric epiblepharon: incisional (modified Hotz procedure with lid margin splitting) and nonincisional. …”
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Utilisation of outpatient care immediately before emergency admission for ambulatory care-sensitive conditions in Japan: a retrospective observational study by Hirotaka Kato, Rei Goto, Ryotaro Nagashima, Tatsuya Matsuzaki, Takayoshi Nagahama

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Management of Anterior Choroidal Artery Aneurysms: A Retrospective Cohort Study by Andrew Falzon, Shigeta Miyake, Tze Phei Kee, Hugo Andrade-Barazarte, Timo Krings

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Differences between frequent emergency department users in a secondary rural hospital and a tertiary suburban hospital in central Japan: a prevalence study by Makoto Kaneko, Masashi Okubo, Michael D Fetters, Machiko Inoue, Allison K Cullen Furgal, Benjamin F Crabtree

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A high fraction of inspired oxygen does not mitigate atelectasis-induced lung tissue hypoxia or injury in experimental acute respiratory distress syndrome by Kentaro Tojo, Takuya Yazawa

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Proposed carbohydrate antigen 19-9 (CA19-9) cut-off values for the detection of pancreatic cancer in patients with poorly controlled diabetes: a real-world study by Taku Yamada, Taichi Minami, Masayo Yamada, Yasuo Terauchi

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Efficacy and safety of pharmacotherapy for cancer cachexia: A systematic review and network meta‐analysis by Hao Chen, Masashi Ishihara, Hiroki Kazahari, Ryusuke Ochiai, Shigeru Tanzawa, Takeshi Honda, Yasuko Ichikawa, Nobuyuki Horita, Hisashi Nagai, Kiyotaka Watanabe, Nobuhiko Seki

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Efficacy and safety of super selective bronchial artery coil embolisation for haemoptysis: a single-centre retrospective observational study by Daijiro Kabata, Ayumi Shintani, Masanori Akira, Masahiko Hara, Hideo Ishikawa, Misaki Ryuge, Jun Takafuji, Mihoko Youmoto, Yukio Nagasaka, Kouji Yamamoto

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Intravenous immunoglobulin for mortality and inflammatory status in patients with sepsis: a retrospective database study by Hayabusa Takano, Hayabusa Takano, Naoki Kanda, Naoki Kanda, Yuji Wakimoto, Hiroyuki Ohbe, Kensuke Nakamura, Kensuke Nakamura

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